-
1
-
-
0027232325
-
Comparison of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases
-
Cameron CE, Grinde B, Jacques P, Jentoft J, Leis J, Wlodawer A, Weber IT. 1993. Comparison of the substrate binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases. J Biol Chem 268:11711-11720.
-
(1993)
J Biol Chem
, vol.268
, pp. 11711-11720
-
-
Cameron, C.E.1
Grinde, B.2
Jacques, P.3
Jentoft, J.4
Leis, J.5
Wlodawer, A.6
Weber, I.T.7
-
2
-
-
0027082783
-
Mechanism of inhibition of the retroviral protease by a RSV peptide substrate representing the cleavage site between the gag p2 and p10 proteins
-
Cameron C, Grinde B, Jentoft J, Leis J, Weber I, Copeland T, Wlodawer A. 1992. Mechanism of inhibition of the retroviral protease by a RSV peptide substrate representing the cleavage site between the gag p2 and p10 proteins. J Biol Chem 33:23735-23741.
-
(1992)
J Biol Chem
, vol.33
, pp. 23735-23741
-
-
Cameron, C.1
Grinde, B.2
Jentoft, J.3
Leis, J.4
Weber, I.5
Copeland, T.6
Wlodawer, A.7
-
4
-
-
0002554107
-
Multifractal measures
-
Peitgen HO, Jurgens H, Saupe D, eds. New York: Springer-Verlag
-
Evertsz CJG, Mandelbrot BB. 1992. Multifractal measures. In: Peitgen HO, Jurgens H, Saupe D, eds. Chaos and fractals. New York: Springer-Verlag. pp 948-949.
-
(1992)
Chaos and Fractals
, pp. 948-949
-
-
Evertsz, C.J.G.1
Mandelbrot, B.B.2
-
7
-
-
0027485083
-
Comparison of conformational characteristics in structurally similar protein pairs
-
Flores TP, Orengo CA, Moss DS, Thornton JM. 1993. Comparison of conformational characteristics in structurally similar protein pairs. Protein Sci 2:1811-1826.
-
(1993)
Protein Sci
, vol.2
, pp. 1811-1826
-
-
Flores, T.P.1
Orengo, C.A.2
Moss, D.S.3
Thornton, J.M.4
-
8
-
-
0002038716
-
The mechanism of the catalytic action of pepsin and related acid proteinases
-
Neuberger A, Brocklehurst K, eds. Amsterdam, The Netherlands: Elsevier Science Publishers
-
Fruton JS. 1987. The mechanism of the catalytic action of pepsin and related acid proteinases. In: Neuberger A, Brocklehurst K, eds. Hydrolytic enzymes. Amsterdam, The Netherlands: Elsevier Science Publishers. pp 1-37.
-
(1987)
Hydrolytic Enzymes
, pp. 1-37
-
-
Fruton, J.S.1
-
9
-
-
0026778802
-
Analysis of substrate interactions of the Rous sarcoma virus and human immunodeficiency virus-1 proteases using a set of systematically altered peptide substrates
-
Grinde B, Cameron CE, Leis J, Weber I, Wlodawer A, Burstein H, Skalka AM. 1992. Analysis of substrate interactions of the Rous sarcoma virus and human immunodeficiency virus-1 proteases using a set of systematically altered peptide substrates. J Biol Chem 267:9491-9498.
-
(1992)
J Biol Chem
, vol.267
, pp. 9491-9498
-
-
Grinde, B.1
Cameron, C.E.2
Leis, J.3
Weber, I.4
Wlodawer, A.5
Burstein, H.6
Skalka, A.M.7
-
10
-
-
0028180528
-
Energy calculations and analysis of HIV-1 protease-inhibitor crystal structures
-
Gustchina A, Sansom C, Prevost M, Richelle J, Wodak SY, Wlodawer A, Weber IT. 1994. Energy calculations and analysis of HIV-1 protease-inhibitor crystal structures. Protein Eng 7:309-317.
-
(1994)
Protein Eng
, vol.7
, pp. 309-317
-
-
Gustchina, A.1
Sansom, C.2
Prevost, M.3
Richelle, J.4
Wodak, S.Y.5
Wlodawer, A.6
Weber, I.T.7
-
11
-
-
84944815610
-
Sayre's equation is a Chernov bound to maximum entropy
-
Harrison RW. 1986. Sayre's equation is a Chernov bound to maximum entropy. Acta Crystallogr A 43:428-430.
-
(1986)
Acta Crystallogr A
, vol.43
, pp. 428-430
-
-
Harrison, R.W.1
-
12
-
-
0001048849
-
Stiffness and energy conservation in the molecular dynamics - An improved integrator
-
Harrison RW. 1993. Stiffness and energy conservation in the molecular dynamics - An improved integrator. J Comp Chem 14:1112-1122.
-
(1993)
J Comp Chem
, vol.14
, pp. 1112-1122
-
-
Harrison, R.W.1
-
13
-
-
0029587028
-
Analysis of six protein structures predicted by comparative modeling techniques
-
Harrison RW, Chatterjee D, Weber IT. 1995. Analysis of six protein structures predicted by comparative modeling techniques. Proteins Struct Funct Genet 23:463-471.
-
(1995)
Proteins Struct Funct Genet
, vol.23
, pp. 463-471
-
-
Harrison, R.W.1
Chatterjee, D.2
Weber, I.T.3
-
14
-
-
0028173594
-
Molecular dynamics simulation of HIV-1 protease with peptide substrate
-
Harrison RW, Weber IT. 1994. Molecular dynamics simulation of HIV-1 protease with peptide substrate. Protein Eng 7:1353-1363.
-
(1994)
Protein Eng
, vol.7
, pp. 1353-1363
-
-
Harrison, R.W.1
Weber, I.T.2
-
15
-
-
0029995624
-
VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands
-
Head RD, Smythe ML, Oprea TI, Waller CL, Green SM, Marshall GR. 1996. VALIDATE: A new method for the receptor-based prediction of binding affinities of novel ligands. J Am Chem Soc 118:3959-3969.
-
(1996)
J Am Chem Soc
, vol.118
, pp. 3959-3969
-
-
Head, R.D.1
Smythe, M.L.2
Oprea, T.I.3
Waller, C.L.4
Green, S.M.5
Marshall, G.R.6
-
16
-
-
0029063951
-
A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site
-
Holloway MK, Wai JM, Halgren TA, Fitzgerald PM, Vacca JP, Dorsey BD, Levin RB, Thompson WJ, Chen LJ, deSolms SJ, Gaffin N, Ghosh AK, Giuliani EA, Graham SL, Guare JP, Hungate RW, Lyle TA, Sanders WM, Tucker TJ, Wiggins M, Wiscount CM, Woltersdorf OW, Young SD, Darke PL, Zugay JA. 1995. A priori prediction of activity for HIV-1 protease inhibitors employing energy minimization in the active site. J Med Chem 38:305-317.
-
(1995)
J Med Chem
, vol.38
, pp. 305-317
-
-
Holloway, M.K.1
Wai, J.M.2
Halgren, T.A.3
Fitzgerald, P.M.4
Vacca, J.P.5
Dorsey, B.D.6
Levin, R.B.7
Thompson, W.J.8
Chen, L.J.9
DeSolms, S.J.10
Gaffin, N.11
Ghosh, A.K.12
Giuliani, E.A.13
Graham, S.L.14
Guare, J.P.15
Hungate, R.W.16
Lyle, T.A.17
Sanders, W.M.18
Tucker, T.J.19
Wiggins, M.20
Wiscount, C.M.21
Woltersdorf, O.W.22
Young, S.D.23
Darke, P.L.24
Zugay, J.A.25
more..
-
17
-
-
0026005186
-
Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism
-
Hyland LJ, Tomaszek TA, Meek TD. 1991. Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism. Biochemistry 30:8454-8463.
-
(1991)
Biochemistry
, vol.30
, pp. 8454-8463
-
-
Hyland, L.J.1
Tomaszek, T.A.2
Meek, T.D.3
-
18
-
-
0025298840
-
Structure of the aspartic protease from Rous sarcoma retrovirus refined at 2 Å resolution
-
Jaskólski M, Miller M, Mohana Rao JK, Leis J, Wlodawer A. 1991. Structure of the aspartic protease from Rous sarcoma retrovirus refined at 2 Å resolution. Biochemistry 29:5889-5898.
-
(1991)
Biochemistry
, vol.29
, pp. 5889-5898
-
-
Jaskólski, M.1
Miller, M.2
Mohana Rao, J.K.3
Leis, J.4
Wlodawer, A.5
-
20
-
-
0028519286
-
Prediction of novel serine proteinase inhibitors
-
Kourinov I, Harrison RW. 1994. Prediction of novel serine proteinase inhibitors. Nature Struct Biol 1:735-743.
-
(1994)
Nature Struct Biol
, vol.1
, pp. 735-743
-
-
Kourinov, I.1
Harrison, R.W.2
-
22
-
-
0024492495
-
Crystal structure of a retroviral protease proves relationship to aspartic protease family
-
Miller M, Jaskólski M, Mohana Rao JK, Wlodawer A. 1989. Crystal structure of a retroviral protease proves relationship to aspartic protease family. Nature 337:576-579.
-
(1989)
Nature
, vol.337
, pp. 576-579
-
-
Miller, M.1
Jaskólski, M.2
Mohana Rao, J.K.3
Wlodawer, A.4
-
24
-
-
0026316549
-
Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid
-
Pettit SC, Simsic J, Loeb DD, Everitt L, Hutchinson CA III, Swanstrom R. 1991. Analysis of retroviral protease cleavage sites reveals two types of cleavage sites and the structural requirements of the P1 amino acid. J Biol Chem 266:14539-14547.
-
(1991)
J Biol Chem
, vol.266
, pp. 14539-14547
-
-
Pettit, S.C.1
Simsic, J.2
Loeb, D.D.3
Everitt, L.4
Hutchinson III, C.A.5
Swanstrom, R.6
-
25
-
-
0028070285
-
Substrate-dependent mechanisms in the catalysis of human immunodeficiency virus protease
-
Polgar L, Szeltner Z, Boros I. 1994. Substrate-dependent mechanisms in the catalysis of human immunodeficiency virus protease. Biochemistry 33:9351-9357.
-
(1994)
Biochemistry
, vol.33
, pp. 9351-9357
-
-
Polgar, L.1
Szeltner, Z.2
Boros, I.3
-
26
-
-
0004161838
-
-
Cambridge: Cambridge University Press
-
Press WH, Teukolsky SA, Vettering WT, Flannery BR. 1992. Numerical recipes in C, 2nd ed. Cambridge: Cambridge University Press. pp 636-639.
-
(1992)
Numerical Recipes in C, 2nd Ed.
, pp. 636-639
-
-
Press, W.H.1
Teukolsky, S.A.2
Vettering, W.T.3
Flannery, B.R.4
-
27
-
-
0042041206
-
UFF: A full periodic table force field for molecular mechanics and molecular dynamics simulations
-
Rappe AK, Casewit CJ, Colwell KS, Goddard WA III, Skiff WM. 1992. UFF: A full periodic table force field for molecular mechanics and molecular dynamics simulations. J Am Chem Soc 114:10024-10035.
-
(1992)
J Am Chem Soc
, vol.114
, pp. 10024-10035
-
-
Rappe, A.K.1
Casewit, C.J.2
Colwell, K.S.3
Goddard III, W.A.4
Skiff, W.M.5
-
28
-
-
0000082544
-
CHAIN - A cristallographic modeling program
-
Sack JS. 1988. CHAIN - A cristallographic modeling program. J Mol Graph 6:224-225.
-
(1988)
J Mol Graph
, vol.6
, pp. 224-225
-
-
Sack, J.S.1
-
30
-
-
0029911723
-
Comparative studies on the substrate specificities of avian myeloblastosis virus proteinase and lentivirus proteinases
-
Tozser J, Bagossi P, Weber IT, Oroszlan S. 1996. Comparative studies on the substrate specificities of avian myeloblastosis virus proteinase and lentivirus proteinases. J Biol Chem 271:6781-6788.
-
(1996)
J Biol Chem
, vol.271
, pp. 6781-6788
-
-
Tozser, J.1
Bagossi, P.2
Weber, I.T.3
Oroszlan, S.4
-
31
-
-
0025336093
-
Comparison of the crystal structures and intersubunit interactions of human immunodeficiency and Rous sarcoma virus proteases
-
Weber IT. 1990. Comparison of the crystal structures and intersubunit interactions of human immunodeficiency and Rous sarcoma virus proteases. J Biol Chem 265:10492-10496.
-
(1990)
J Biol Chem
, vol.265
, pp. 10492-10496
-
-
Weber, I.T.1
-
32
-
-
85045611231
-
Models of HIV-1 protease with peptides representing its natural substrates
-
Forthcoming
-
Weber IT, Cavanaugh DS, Harrison RW. 1997. Models of HIV-1 protease with peptides representing its natural substrates. J Mol Struct (Theochem). Forthcoming.
-
(1997)
J Mol Struct (Theochem)
-
-
Weber, I.T.1
Cavanaugh, D.S.2
Harrison, R.W.3
-
33
-
-
0029790550
-
Molecular mechanics calculations on HIV-1 protease with peptide substrates correlate with experimental data
-
Weber IT, Harrison RW. 1996. Molecular mechanics calculations on HIV-1 protease with peptide substrates correlate with experimental data. Protein Eng 9:679-690.
-
(1996)
Protein Eng
, vol.9
, pp. 679-690
-
-
Weber, I.T.1
Harrison, R.W.2
-
34
-
-
0027218692
-
Structure-based inhibitors of HIV-1 protease
-
Wlodawer A, Erickson JW. 1993. Structure-based inhibitors of HIV-1 protease. Annu Rev Biochem 62:543-585.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 543-585
-
-
Wlodawer, A.1
Erickson, J.W.2
-
35
-
-
0024412506
-
Conserved folding in retroviral proteases - Crystal structure of a synthetic HIV-1 protease
-
Wlodawer A, Miller M, Jaskolski M, Sathyanarayana BK, Baldwin E, Weber IT, Selk LM, Clawson L, Schneider J, Kent SBH. 1989. Conserved folding in retroviral proteases - Crystal structure of a synthetic HIV-1 protease. Science 245:616-621.
-
(1989)
Science
, vol.245
, pp. 616-621
-
-
Wlodawer, A.1
Miller, M.2
Jaskolski, M.3
Sathyanarayana, B.K.4
Baldwin, E.5
Weber, I.T.6
Selk, L.M.7
Clawson, L.8
Schneider, J.9
Kent, S.B.H.10
-
36
-
-
0023645954
-
Structure of form III crystals of bovine pancreatic trypsin inhibitor
-
Wlodawer A, Nachman J, Gilliland GL, Gallagher W, Woodward C. 1987. Structure of form III crystals of bovine pancreatic trypsin inhibitor. J Mol Biol 198:469-480.
-
(1987)
J Mol Biol
, vol.198
, pp. 469-480
-
-
Wlodawer, A.1
Nachman, J.2
Gilliland, G.L.3
Gallagher, W.4
Woodward, C.5
-
37
-
-
0029009275
-
Sugar specificity of human β-cell glucokinase - Correlation of molecular models with kinetic measurements
-
Xu LZ, Weber IT, Harrison RW, Gidh-Jain M, Pilkis SJ. 1995. Sugar specificity of human β-cell glucokinase - Correlation of molecular models with kinetic measurements. Biochemistry 34:6083-6092.
-
(1995)
Biochemistry
, vol.34
, pp. 6083-6092
-
-
Xu, L.Z.1
Weber, I.T.2
Harrison, R.W.3
Gidh-Jain, M.4
Pilkis, S.J.5
-
38
-
-
0028564999
-
The structures of RNase A complexed with 3′CMP and dCpA - Active site conformation and conserved water molecules
-
Zegers I, Maes D, Dao-Thi MH, Poortmans F, Palmer R, Wyns L. 1994. The structures of RNase A complexed with 3′CMP and dCpA - Active site conformation and conserved water molecules. Protein Sci 3:2322-2339.
-
(1994)
Protein Sci
, vol.3
, pp. 2322-2339
-
-
Zegers, I.1
Maes, D.2
Dao-Thi, M.H.3
Poortmans, F.4
Palmer, R.5
Wyns, L.6
|