Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase implication for inhibitor specificity

Journal of Biological Chemistry

Volumn 277, Issue 41, 2002, Pages 38797-38802

  Munshi, Sanjeev ^a   Kornienko, Maria ^a   Hall, Dawn L ^a   Reid, John C ^a   Waxman, Lloyd ^a   Stirdivant, Steven M ^a   Darke, Paul L ^a   Kuo, Lawrence C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOLOGICAL MEMBRANES; CHEMICAL ACTIVATION; CONFORMATIONS; ENZYMES; MONOMERS; X RAYS;

RECEPTORS;

INSULIN;

ADENOSINE TRIPHOSPHATE; DNA; INSULIN RECEPTOR KINASE; SOMATOMEDIN C RECEPTOR;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME PURIFICATION; ENZYME STRUCTURE; INSECT CELL; LEPIDOPTERA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; INSECTS; MODELS, MOLECULAR; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 1;

INSECTA; LEPIDOPTERA;

EID: 0037064032     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205580200     Document Type: Article

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