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Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 22, 2004, Pages 5543-5546

Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors

(16) Zhao, Hongyu a Liu, Gang a Xin, Zhili a Serby, Michael D a Pei, Zhonghua a Szczepankiewicz, Bruce G a Hajduk, Philip J a Abad Zapatero, Cele a Hutchins, Charles W a Lubben, Thomas H a Ballaron, Stephen J a Haasch, Deanna L a Kaszubska, Wiweka a Rondinone, Cristina M a Trevillyan, James M a Jirousek, Michael R a

a ABBOTT LABORATORIES (United States)

Author keywords

Cell permeable; PTP1B; Selective

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; ISOXAZOLE DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR;

ARTICLE; CELL MEMBRANE PERMEABILITY; CRYSTAL STRUCTURE; DRUG BINDING SITE; DRUG CONFORMATION; DRUG POTENCY; DRUG SELECTIVITY; HYDROPHILICITY; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

EID: 5144220756 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2004.08.063 Document Type: Article

Times cited : (82)

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