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Volumn 34, Issue 7, 2006, Pages 2056-2066

dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA (APURINIC OR APYRIMIDINIC SITE) LYASE; GENOMIC DNA; GLYCINE; MUTANT PROTEIN; PROTEIN DUT1 1; SACCHAROMYCES CEREVISIAE PROTEIN; SERINE; UNCLASSIFIED DRUG; URACIL DNA GLYCOSYLTRANSFERASE; DUTP PYROPHOSPHATASE; FUNGAL DNA; INORGANIC PYROPHOSPHATASE; URACIL;

EID: 33645924354     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl139     Document Type: Article
Times cited : (54)

References (50)
  • 1
    • 0348140585 scopus 로고    scopus 로고
    • Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisiae
    • Boiteux,S. and Guillet,M. (2004) Abasic sites in DNA: Repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst), 3, 1-12.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1-12
    • Boiteux, S.1    Guillet, M.2
  • 2
    • 0037013854 scopus 로고    scopus 로고
    • Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae
    • Guillet,M. and Boiteux,S. (2002) Endogenous DNA abasic sites cause cell death in the absence of Apn1, Apn2 and Rad1/Rad10 in Saccharomyces cerevisiae. EMBO J., 21, 2833-2841.
    • (2002) EMBO J. , vol.21 , pp. 2833-2841
    • Guillet, M.1    Boiteux, S.2
  • 3
    • 4444281763 scopus 로고    scopus 로고
    • Requirement of yeast Rad1-Rad10 nuclease for the removal of 3′-blocked termini from DNA strand breaks induced by reactive oxygen species
    • Guzder,S.N., Torres-Ramos,C., Johnson,R.E., Haracska,L., Prakash,L. and Prakash,S. (2004) Requirement of yeast Rad1-Rad10 nuclease for the removal of 3′-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev., 18, 2283-2291.
    • (2004) Genes Dev. , vol.18 , pp. 2283-2291
    • Guzder, S.N.1    Torres-Ramos, C.2    Johnson, R.E.3    Haracska, L.4    Prakash, L.5    Prakash, S.6
  • 4
    • 18844375357 scopus 로고    scopus 로고
    • Abrogation of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks in Saccharomyces cerevisiae
    • Karumbati,A.S. and Wilson,T.E. (2005) Abrogation of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks in Saccharomyces cerevisiae. Genetics, 169, 1833-1844.
    • (2005) Genetics , vol.169 , pp. 1833-1844
    • Karumbati, A.S.1    Wilson, T.E.2
  • 5
    • 10944251591 scopus 로고    scopus 로고
    • Repair and genetic consequences of endogenous DNA base damage in mammalian cells
    • Barnes,D.E. and Lindahl,T. (2004) Repair and genetic consequences of endogenous DNA base damage in mammalian cells. Annu. Rev. Genet., 38, 445-476.
    • (2004) Annu. Rev. Genet. , vol.38 , pp. 445-476
    • Barnes, D.E.1    Lindahl, T.2
  • 6
    • 0242412184 scopus 로고    scopus 로고
    • Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae
    • Guillet,M. and Boiteux,S. (2003) Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol. Cell Biol., 23, 8386-8394.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 8386-8394
    • Guillet, M.1    Boiteux, S.2
  • 7
    • 0011731413 scopus 로고
    • Enzymatic synthesis of deoxyribonucleic acid, III. The incorporation of pyrimidine and purine analogues into deoxyribonucleic acid
    • Bessman,M.J., Lehman,I.R., Adler,J., Zimmerman,S.B., Simms,E.S. and Kornberg,A. (1958) Enzymatic synthesis of deoxyribonucleic acid, III. The incorporation of pyrimidine and purine analogues into deoxyribonucleic acid. Proc. Natl Acad. Sci. USA, 44, 633-640.
    • (1958) Proc. Natl Acad. Sci. USA , vol.44 , pp. 633-640
    • Bessman, M.J.1    Lehman, I.R.2    Adler, J.3    Zimmerman, S.B.4    Simms, E.S.5    Kornberg, A.6
  • 8
    • 0017866954 scopus 로고
    • Deoxyuridine triphosphatase of Escherichia coli. Purification, properties and use as a reagent to reduce uracil incorporation into DNA
    • Shlomai,J. and Kornberg,A. (1978) Deoxyuridine triphosphatase of Escherichia coli. Purification, properties and use as a reagent to reduce uracil incorporation into DNA. J. Biol. Chem., 253, 3305-3312.
    • (1978) J. Biol. Chem. , vol.253 , pp. 3305-3312
    • Shlomai, J.1    Kornberg, A.2
  • 9
    • 0018802403 scopus 로고
    • Utilization in vitro of deoxyuridine triphosphate in DNA synthesis by DNA polymerases alpha and beta from calf thymus
    • Yoshida,S. and Masaki,S. (1979) Utilization in vitro of deoxyuridine triphosphate in DNA synthesis by DNA polymerases alpha and beta from calf thymus. Biochim. Biophys Acta, 561, 396-402.
    • (1979) Biochim. Biophys Acta , vol.561 , pp. 396-402
    • Yoshida, S.1    Masaki, S.2
  • 10
    • 0023949768 scopus 로고
    • Purification and characterization of porcine liver DNA polymerase gamma: Utilization of dUTP and dTTP during in vitro DNA synthesis
    • Mosbaugh,D.W. (1988) Purification and characterization of porcine liver DNA polymerase gamma: Utilization of dUTP and dTTP during in vitro DNA synthesis. Nucleic Acids Res., 16, 5645-5659.
    • (1988) Nucleic Acids Res. , vol.16 , pp. 5645-5659
    • Mosbaugh, D.W.1
  • 12
    • 0023967987 scopus 로고
    • Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli
    • el-Hajj,H.H., Zhang,H. and Weiss,B. (1988) Lethality of a dut (deoxyuridine triphosphatase) mutation in Escherichia coli. J. Bacteriol., 170, 1069-1075.
    • (1988) J. Bacteriol. , vol.170 , pp. 1069-1075
    • el-Hajj, H.H.1    Zhang, H.2    Weiss, B.3
  • 13
    • 0017886373 scopus 로고
    • Escherichia coli mutants deficient in deoxyuridine triphosphatase
    • Hochhauser,S.J. and Weiss,B. (1978) Escherichia coli mutants deficient in deoxyuridine triphosphatase. J. Bacteriol., 134, 157-166.
    • (1978) J. Bacteriol. , vol.134 , pp. 157-166
    • Hochhauser, S.J.1    Weiss, B.2
  • 14
    • 1542616353 scopus 로고    scopus 로고
    • Chromosomal fragmentation in dUTPase-deficient mutants of Escherichia coli and its recombinational repair
    • Kouzminova,E.A. and Kuzminov,A. (2004) Chromosomal fragmentation in dUTPase-deficient mutants of Escherichia coli and its recombinational repair. Mol. Microbiol., 51, 1279-1295.
    • (2004) Mol. Microbiol. , vol.51 , pp. 1279-1295
    • Kouzminova, E.A.1    Kuzminov, A.2
  • 15
    • 0019921462 scopus 로고
    • Role of exonuclease III in the base excision repair of uracil-containing DNA
    • Taylor,A.F. and Weiss,B. (1982) Role of exonuclease III in the base excision repair of uracil-containing DNA. J. Bacteriol., 151, 351-357.
    • (1982) J. Bacteriol. , vol.151 , pp. 351-357
    • Taylor, A.F.1    Weiss, B.2
  • 16
    • 0013608322 scopus 로고
    • Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA
    • Tye,B.K., Nyman,P.O., Lehman,I.R., Hochhauser,S. and Weiss,B. (1977) Transient accumulation of Okazaki fragments as a result of uracil incorporation into nascent DNA. Proc. Natl Acad. Sci. USA, 74, 154-157.
    • (1977) Proc. Natl Acad. Sci. USA , vol.74 , pp. 154-157
    • Tye, B.K.1    Nyman, P.O.2    Lehman, I.R.3    Hochhauser, S.4    Weiss, B.5
  • 17
    • 0022443767 scopus 로고
    • Deoxyuridine misincorporation causes site-specific mutational lesions in the lac1 gene of Escherichia coli
    • Sedwick,W.D., Brown,O.E. and Glickman,B.W. (1986) Deoxyuridine misincorporation causes site-specific mutational lesions in the lac1 gene of Escherichia coli. Mutat Res., 162, 7-20.
    • (1986) Mutat Res. , vol.162 , pp. 7-20
    • Sedwick, W.D.1    Brown, O.E.2    Glickman, B.W.3
  • 18
    • 0019475150 scopus 로고
    • Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli
    • Warner,H.R., Duncan,B.K., Garrett,C. and Neuhard,J. (1981) Synthesis and metabolism of uracil-containing deoxyribonucleic acid in Escherichia coli. J. Bacteriol., 145, 687-695.
    • (1981) J. Bacteriol. , vol.145 , pp. 687-695
    • Warner, H.R.1    Duncan, B.K.2    Garrett, C.3    Neuhard, J.4
  • 19
    • 0027426749 scopus 로고
    • dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae
    • Gadsden,M.H., McIntosh,E.M., Game,J.C., Wilson,P.J. and Haynes,R.H. (1993) dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae. EMBO J., 12, 4425-4431.
    • (1993) EMBO J. , vol.12 , pp. 4425-4431
    • Gadsden, M.H.1    McIntosh, E.M.2    Game, J.C.3    Wilson, P.J.4    Haynes, R.H.5
  • 20
    • 0036788148 scopus 로고    scopus 로고
    • Roles of uracil-DNA glycosylase and dUTPase in virus replication
    • Chen,R., Wang,H. and Mansky,L.M. (2002) Roles of uracil-DNA glycosylase and dUTPase in virus replication. J. Gen. Virol., 83, 2339-2345.
    • (2002) J. Gen. Virol. , vol.83 , pp. 2339-2345
    • Chen, R.1    Wang, H.2    Mansky, L.M.3
  • 21
    • 0034734383 scopus 로고    scopus 로고
    • Structure and function in the uracil-DNA glycosylase superfamily
    • Pearl,L.H. (2000) Structure and function in the uracil-DNA glycosylase superfamily. Mutat Res., 460, 165-181.
    • (2000) Mutat Res. , vol.460 , pp. 165-181
    • Pearl, L.H.1
  • 22
  • 23
    • 0032837333 scopus 로고    scopus 로고
    • Evolution and horizontal transfer of dUTPase-encoding genes in viruses and their hosts
    • Baldo,A.M. and McClure,M.A. (1999) Evolution and horizontal transfer of dUTPase-encoding genes in viruses and their hosts. J. Virol., 73, 7710-7721.
    • (1999) J. Virol. , vol.73 , pp. 7710-7721
    • Baldo, A.M.1    McClure, M.A.2
  • 24
    • 0034234872 scopus 로고    scopus 로고
    • dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: Association with survival and response to 5-fluorouracil in colorectal cancer
    • Ladner,R.D., Lynch,F.J., Groshen,S., Xiong,Y.P., Sherrod,A., Caradonna,S.J., Stoehlmacher,J. and Lenz,H.J. (2000) dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer. Cancer Res., 60, 3493-3503.
    • (2000) Cancer Res. , vol.60 , pp. 3493-3503
    • Ladner, R.D.1    Lynch, F.J.2    Groshen, S.3    Xiong, Y.P.4    Sherrod, A.5    Caradonna, S.J.6    Stoehlmacher, J.7    Lenz, H.J.8
  • 25
    • 0036731991 scopus 로고    scopus 로고
    • dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae
    • Tinkelenberg,B.A., Hansbury,M.J. and Ladner,R.D. (2002) dUTPase and uracil-DNA glycosylase are central modulators of antifolate toxicity in Saccharomyces cerevisiae. Cancer Res., 62, 4909-4915.
    • (2002) Cancer Res. , vol.62 , pp. 4909-4915
    • Tinkelenberg, B.A.1    Hansbury, M.J.2    Ladner, R.D.3
  • 26
    • 0020803243 scopus 로고
    • Genetic effects of UV irradiation on excision-proficient and -deficient yeast during meiosis
    • Resnick,M.A., Game,J.C. and Stasiewicz,S. (1983) Genetic effects of UV irradiation on excision-proficient and -deficient yeast during meiosis. Genetics, 104, 603-618.
    • (1983) Genetics , vol.104 , pp. 603-618
    • Resnick, M.A.1    Game, J.C.2    Stasiewicz, S.3
  • 27
    • 0025978950 scopus 로고
    • Micromanipulation and dissection of asci
    • Sherman,F. and Hicks,J. (1991) Micromanipulation and dissection of asci. Methods Enzymol., 194, 21-37.
    • (1991) Methods Enzymol. , vol.194 , pp. 21-37
    • Sherman, F.1    Hicks, J.2
  • 28
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Gietz,D., St Jean,A., Woods,R.A. and Schiestl,R.H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res., 20, 1425.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1425
    • Gietz, D.1    St Jean, A.2    Woods, R.A.3    Schiestl, R.H.4
  • 29
    • 0028586017 scopus 로고
    • Regulatable promoters of Saccharomyces cerevisiae: Comparison of transcriptional activity and their use for heterologous expression
    • Mumberg,D., Muller,R. and Funk,M. (1994) Regulatable promoters of Saccharomyces cerevisiae: Comparison of transcriptional activity and their use for heterologous expression. Nucleic Acids Res., 22, 5767-5768.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 5767-5768
    • Mumberg, D.1    Muller, R.2    Funk, M.3
  • 30
    • 0025129813 scopus 로고
    • Cloning by function: An alternative approach for identifying yeast homologs of genes from other organisms
    • Kranz,J.E. and Holm,C. (1990) Cloning by function: An alternative approach for identifying yeast homologs of genes from other organisms. Proc. Natl Acad. Sci. USA, 87, 6629-6633.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6629-6633
    • Kranz, J.E.1    Holm, C.2
  • 31
    • 0025785410 scopus 로고
    • A family of low and high copy replicative, integrative and single-stranded S. cerevisiae/E. coli shuttle vectors
    • Bonneaud,N., Ozier-Kalogeropoulos,O., Li,G.Y., Labouesse,M., Minvielle-Sebastia,L. and Lacroute,F. (1991) A family of low and high copy replicative, integrative and single-stranded S. cerevisiae/E. coli shuttle vectors. Yeast, 7, 609-615.
    • (1991) Yeast , vol.7 , pp. 609-615
    • Bonneaud, N.1    Ozier-Kalogeropoulos, O.2    Li, G.Y.3    Labouesse, M.4    Minvielle-Sebastia, L.5    Lacroute, F.6
  • 34
    • 4644303632 scopus 로고    scopus 로고
    • The post-replication repair RAD18 and RAD6 genes are involved in the prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine n Saccharomyces cerevisiae
    • de Padula,M., Slezak,G., Auffret van Der Kemp,P. and Boiteux,S. (2004) The post-replication repair RAD18 and RAD6 genes are involved in the prevention of spontaneous mutations caused by 7,8-dihydro-8-oxoguanine n Saccharomyces cerevisiae. Nucleic Acids Res. 32, 5003-5010.
    • (2004) Nucleic Acids Res. , vol.32 , pp. 5003-5010
    • de Padula, M.1    Slezak, G.2    Auffret van Der Kemp, P.3    Boiteux, S.4
  • 35
    • 0021906691 scopus 로고
    • Genetic analysis of the mitotic transmission of minichromosomes
    • Koshland,D., Kent,J.C. and Hartwell,L.H. (1985) Genetic analysis of the mitotic transmission of minichromosomes. Cell, 40, 393-403.
    • (1985) Cell , vol.40 , pp. 393-403
    • Koshland, D.1    Kent, J.C.2    Hartwell, L.H.3
  • 36
    • 33745210986 scopus 로고    scopus 로고
    • Use of yeast for detection of endogenous abasic lesions, their source and tehir repair
    • in press
    • Boiteux,S. and Guillet,M. (2006) Use of yeast for detection of endogenous abasic lesions, their source and tehir repair. Methods Enzymol., 408, in press.
    • (2006) Methods Enzymol. , pp. 408
    • Boiteux, S.1    Guillet, M.2
  • 37
    • 0034108218 scopus 로고    scopus 로고
    • Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast
    • Torres-Ramos,C.A., Johnson,R.E., Prakash,L. and Prakash,S. (2000) Evidence for the involvement of nucleotide excision repair in the removal of abasic sites in yeast. Mol. Cell Biol., 20, 3522-3528.
    • (2000) Mol. Cell Biol. , vol.20 , pp. 3522-3528
    • Torres-Ramos, C.A.1    Johnson, R.E.2    Prakash, L.3    Prakash, S.4
  • 38
    • 5644258283 scopus 로고    scopus 로고
    • Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase
    • Barabas,O., Pongracz,V., Kovari,J., Wilmanns,M. and Vertessy,B.G. (2004) Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase. J. Biol. Chem., 279, 42907-42915.
    • (2004) J. Biol. Chem. , vol.279 , pp. 42907-42915
    • Barabas, O.1    Pongracz, V.2    Kovari, J.3    Wilmanns, M.4    Vertessy, B.G.5
  • 39
    • 0024969622 scopus 로고
    • Molecular cloning and primary structure of the uracil-DNA-glycosylase gene from Saccharomyces cerevisiae
    • Percival,K.J., Klein,M.B. and Burgers,P.M. (1989) Molecular cloning and primary structure of the uracil-DNA-glycosylase gene from Saccharomyces cerevisiae. J. Biol. Chem., 264, 2593-2598.
    • (1989) J. Biol. Chem. , vol.264 , pp. 2593-2598
    • Percival, K.J.1    Klein, M.B.2    Burgers, P.M.3
  • 40
    • 0025790276 scopus 로고
    • The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair
    • Impellizzeri,K.J., Anderson,B. and Burgers,P.M. (1991) The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair. J. Bacteriol., 173, 6807-6810.
    • (1991) J. Bacteriol. , vol.173 , pp. 6807-6810
    • Impellizzeri, K.J.1    Anderson, B.2    Burgers, P.M.3
  • 41
    • 0026711129 scopus 로고
    • Multiple mutant of Escherichia coli synthesizing virtually thymineless DNA during limited growth
    • el-Hajj,H.H., Wang,L. and Weiss,B. (1992) Multiple mutant of Escherichia coli synthesizing virtually thymineless DNA during limited growth. J. Bacteriol., 174, 4450-4456.
    • (1992) J. Bacteriol. , vol.174 , pp. 4450-4456
    • el-Hajj, H.H.1    Wang, L.2    Weiss, B.3
  • 42
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl,T. (1993) Instability and decay of the primary structure of DNA. Nature, 362, 709-715.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 43
    • 0037178748 scopus 로고    scopus 로고
    • Interfaces between the detection, signaling and repair of DNA damage
    • Rouse,J. and Jackson,S.P. (2002) Interfaces between the detection, signaling and repair of DNA damage. Science, 297, 547-551.
    • (2002) Science , vol.297 , pp. 547-551
    • Rouse, J.1    Jackson, S.P.2
  • 47
    • 0036924972 scopus 로고    scopus 로고
    • Difference between deoxyribose- and tetrahydrofuran-type abasic sites in the in vivo mutagenic responses in yeast
    • Otsuka,C., Sanadai,S., Hata,Y., Okuto,H., Noskov,V.N., Loakes,D. and Negishi,K. (2002) Difference between deoxyribose- and tetrahydrofuran-type abasic sites in the in vivo mutagenic responses in yeast. Nucleic Acids Res., 30, 5129-5135.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5129-5135
    • Otsuka, C.1    Sanadai, S.2    Hata, Y.3    Okuto, H.4    Noskov, V.N.5    Loakes, D.6    Negishi, K.7
  • 48
    • 15544386652 scopus 로고    scopus 로고
    • The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer
    • Gibbs,P.E., McDonald,J., Woodgate,R. and Lawrence,C.W. (2005) The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer. Genetics, 169, 575-582.
    • (2005) Genetics , vol.169 , pp. 575-582
    • Gibbs, P.E.1    McDonald, J.2    Woodgate, R.3    Lawrence, C.W.4
  • 49
    • 29144433943 scopus 로고    scopus 로고
    • Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA
    • Auerbach,P., Bennett,R.A., Bailey,E.A., Krokan,H.E. and Demple,B. (2005) Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA. Proc. Natl Acad. Sci. USA, 102, 17711-17716.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 17711-17716
    • Auerbach, P.1    Bennett, R.A.2    Bailey, E.A.3    Krokan, H.E.4    Demple, B.5
  • 50
    • 0026603423 scopus 로고
    • Uracil interference, a rapid and general method for defining protein-DNA interactions involving the 5-methyl group of thymines: The GCN4-DNA complex
    • Pu,W.T. and Struhl,K. (1992) Uracil interference, a rapid and general method for defining protein-DNA interactions involving the 5-methyl group of thymines: The GCN4-DNA complex. Nucleic Acids Res., 20, 771-775.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 771-775
    • Pu, W.T.1    Struhl, K.2


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