Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate Synthase-Inhibited cells using a modified DNA polymerase assay

Biochemical Pharmacology

Volumn 54, Issue 5, 1997, Pages 635-638

  Horowitz, Robert W ^a   Zhang, Hong yang ^a   Schwartz, Edward L ^a   Ladner, Robert D ^b   Wadler, Scott ^a,c  

^a ALBERT EINSTEIN CANCER CENTER   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^c MONTEFIORE MEDICAL CENTER   (United States)

Author keywords

Antifolate; Colon cancer; Deoxynucleotides; DNA polymerase; Thymidylate synthase

Indexed keywords

DEOXYURIDINE TRIPHOSPHATE DERIVATIVE; DNA POLYMERASE; RALTITREXED; THYMIDINE TRIPHOSPHATE; THYMIDYLATE SYNTHASE;

ARTICLE; CELL STRAIN HT29; COLON CARCINOMA; ENZYME INHIBITION; PRIORITY JOURNAL;

ADENOCARCINOMA; ANTIMETABOLITES, ANTINEOPLASTIC; COLONIC NEOPLASMS; DEOXYURACIL NUCLEOTIDES; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; KINETICS; PYROPHOSPHATASES; QUINAZOLINES; TEMPLATES, GENETIC; THIOPHENES; THYMIDYLATE SYNTHASE; THYMINE NUCLEOTIDES; TUMOR CELLS, CULTURED;

EID: 0030804554     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(97)00259-1     Document Type: Article

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