Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major

Protein Science

Volumn 10, Issue 7, 2001, Pages 1426-1433

  Hidalgo Zarco, Fernando ^a   Camacho, Ana G ^a   Bernier Villamor, Victor ^a   Nord, Johan ^b   Ruiz Pérez, Luis Miguel ^a   González Pacanowska, Dolores ^a  

^a INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Competitive inhibition; dUDPase; dUTPase; Leishmania major; Nucleotide metabolism; Uracil

Indexed keywords

ALPHA BETA IMIDO DEOXYURIDINE TRIPHOSPHATE; DEOXYURIDINE DIPHOSPHATE PYROPHOSPHATASE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; NUCLEOSIDE TRIPHOSPHATE; PARATHION; PYROPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; DISSOCIATION; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; HYDROLYSIS; LEISHMANIASIS; MICHAELIS CONSTANT; PRIORITY JOURNAL; SPECTROPHOTOMETRY; TRYPANOSOMA;

ANIMALS; CATIONS; DEOXYURACIL NUCLEOTIDES; DIMERIZATION; HYDROGEN-ION CONCENTRATION; KINETICS; LEISHMANIA MAJOR; PYROPHOSPHATASES; SUBSTRATE SPECIFICITY; TEMPERATURE;

BACTERIA (MICROORGANISMS); EUKARYOTA; LEISHMANIA MAJOR; PROTOZOA; TRYPANOSOMA; TRYPANOSOMATIDAE;

EID: 0034966740     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.48801     Document Type: Article

References (32)

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