Protein kinase B (PKB/Akt) is required for the completion of meiosis in mouse oocytes

Developmental Biology

Volumn 314, Issue 1, 2008, Pages 215-223

  Hoshino, Yumi ^a   Sato, Eimei ^a  

^a TOHOKU UNIVERSITY   (Japan)

Author keywords

Akt protein kinase B; Fertilization; Meiotic maturation; Microinjection; Mouse oocyte; Peptide; Polar body emission; SH 6 Akt inhibitor III; Spindle

Indexed keywords

PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CHROMOSOME; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FERTILIZATION; MEIOSIS; MICROTUBULE; MOUSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

EID: 38349088626     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2007.12.005     Document Type: Article

References (34)

1. Alessi D.R., Andjelkovic M., Caudwell B., Cron P., Morrice N., Cohen P., and Hemmings B.A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 15 (1996) 6541-6551
2. Beaujean N., Bouniol-Baly C., Monod C., Kissa K., Jullien D., Aulner N., Amirand C., Debey P., and Käs E. Induction of early transcription in one-cell mouse embryos by microinjection of the nonhistone chromosomal protein HMG-I. Dev. Biol. 221 (2000) 337-354
3. Cheng J.Q., Altomare D.A., Klein M.A., Lee W.C., Kruh G.D., Lissy N.A., and Testa J.R. Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis. Oncogene 14 (1997) 2793-2801
4. Cho H., Mu J., Kim J.K., Thorvaldsen J.L., Chu Q., Crenshaw III E.B., Kaestner K.H., Bartolomei M.S., Shulman G.I., and Birnbaum M.J. Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science 292 (2001) 1728-1731
5. Cho H., Thorvaldsen J.L., Chu Q., Feng F., and Birnbaum M.J. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276 (2001) 38349-38352
6. Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes Dev. 13 (1999) 2905-2927
7. Dumont J., Million K., Sunderland K., Rassinier P., Lim H., Leader B., and Verlhac M.H. Formin-2 is required for spindle migration and for the late steps of cytokinesis in mouse oocytes. Dev. Biol. 301 (2007) 254-265
8. Easton R.M., Cho H., Roovers K., Shineman D.W., Mizrahi M., Forman M.S., Lee V.M., Szabolcs M., de Jong R., Oltersdorf T., Ludwig T., Efstratiadis A., and Birnbaum M.J. Role for Akt3/protein kinase Bgamma in attainment of normal brain size. Mol. Cell. Biol. 25 (2005) 1869-1878
9. Eyster C.A., Duggins Q.S., Gorbsky G.J., and Olson A.L. Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility. J. Biol. Chem. 281 (2006) 39719-39727
10. Favaro P.M., de Souza Medina S., Traina F., Bassères D.S., Costa F.F., and Saad S.T. Human leukocyte formin: a novel protein expressed in lymphoid malignancies and associated with Akt. Biochem. Biophys. Res. Commun. 311 (2003) 365-371
11. Feng J., Park J., Cron P., Hess D., and Hemmings B.A. Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J. Biol. Chem. 279 (2004) 41189-41196
12. Garofalo R.S., Orena S.J., Rafidi K., Torchia A.J., Stock J.L., Hildebrandt A.L., Coskran T., Black S.C., Brees D.J., Wicks J.R., McNeish J.D., and Coleman K.G. Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta. J. Clin. Invest. 112 (2003) 197-208
13. Hanada M., Feng J., and Hemmings B.A. Structure, regulation and function of PKB/AKT-a major therapeutic target. Biochim. Biophys. Acta 1697 (2004) 3-16
14. Hoshino Y., Yokoo M., Yoshida N., Sasada H., Matsumoto H., and Sato E. Phosphatidylinositol 3-kinase and Akt participate in the FSH-induced meiotic maturation of mouse oocytes. Mol. Reprod. Dev. 69 (2004) 77-86
15. Kalous J., Solc P., Baran V., Kubelka M., Schultz R.M., and Motlik J. PKB/AKT is involved in resumption of meiosis in mouse oocytes. Biol. Cell 98 (2006) 111-123
16. Kandel E.S., Skeen J., Majewski N., Di Cristofano A., Pandolfi P.P., Feliciano C.S., Gartel A., and Hay N. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Mol. Cell. Biol. 22 (2002) 7831-7841
17. Kim S., Jee K., Kim D., Koh H., and Chung J. Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1. J. Biol. Chem. 276 (2001) 12864-12870
18. Lawlor M.A., and Alessi D.R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?. J. Cell. Sci. 114 (2001) 2903-2910
19. Majumder P.K., Febbo P.G., Bikoff R., Berger R., Xue Q., McMahon L.M., Manola J., Brugarolas J., McDonnell T.J., Golub T.R., Loda M., Lane H.A., and Sellers W.R. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. Nat. Med. 10 (2004) 594-601
20. Matsumoto H., Ma W., Smalley W., Trzaskos J., Breyer R.M., and Dey S.K. Diversification of cyclooxygenase-2-derived prostaglandins in ovulation and implantation. Biol. Reprod. 64 (2001) 1557-1565
21. Nicholson K.M., and Anderson N.G. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal. 14 (2002) 381-395
22. Onishi K., Higuchi M., Asakura T., Masuyama N., and Gotoh Y. The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes Cells 12 (2007) 535-546
23. Peng X.D., Xu P.Z., Chen M.L., Hahn-Windgassen A., Skeen J., Jacobs J., Sundararajan D., Chen W.S., Crawford S.E., Coleman K.G., and Hay N. Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev. 17 (2003) 1352-1365
24. Riley J.K., Carayannopoulos M.O., Wyman A.H., Chi M., Ratajczak C.K., and Moley K.H. The PI3K/Akt pathway is present and functional in the preimplantation mouse embryo. Dev. Biol. 284 (2005) 377-386
25. Sarbassov D.D., Guertin D.A., Ali S.M., and Sabatini D.M. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307 (2005) 1098-1101
26. Scheid M.P., Marignani P.A., and Woodgett J.R. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B. Mol. Cell. Biol. 22 (2002) 6247-6260
27. Shtivelman E., Sussman J., and Stokoe D. A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle. Curr. Biol. 12 (2002) 919-924
28. Troussard A.A., Mawji N.M., Ong C., Mui A., St-Arnaud R., and Dedhar S. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J. Biol. Chem. 278 (2003) 22374-22378
29. Tschopp O., Yang Z.Z., Brodbeck D., Dummler B.A., Hemmings-Mieszczak M., Watanabe T., Michaelis T., Frahm J., and Hemmings B.A. Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis. Development 132 (2005) 2943-2954
30. Vanhaesebroeck B., and Alessi D.R. The PI3K-PDK1 connection: more than just a road to PKB. Biochem. J. 346 Pt 3 (2000) 561-576
31. Viniegra J.G., Martínez N., Modirassari P., Losa J.H., Parada Cobo C., Lobo V.J., Luquero C.I., Alvarez-Vallina L., Ramón y Cajal S., Rojas J.M., and Sánchez-Prieto R. Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM. J. Biol. Chem. 280 (2005) 4029-4036
32. Wakefield J.G., Stephens D.J., and Tavaré J.M. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J. Cell. Sci. 116 (2003) 637-646
33. Wang X., Liu X.T., Dunn R., Ohl D.A., and Smith G.D. Glycogen synthase kinase-3 regulates mouse oocyte homologue segregation. Mol. Reprod. Dev. 64 (2003) 96-105
34. Yang Z.Z., Tschopp O., Hemmings-Mieszczak M., Feng J., Brodbeck D., Perentes E., and Hemmings B.A. Protein kinase B alpha/Akt1 regulates placental development and fetal growth. J. Biol. Chem. 278 (2003) 32124-32131