Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation

Journal of Biological Chemistry

Volumn 277, Issue 15, 2002, Pages 13192-13201

  Irving, James A ^a   Shushanov, Sain S ^a   Pike, Robert N ^a   Popova, Evgenya Y ^b   Brömme, Dieter ^b   Coetzer, Theresa H T ^c   Bottomley, Stephen P ^c   Boulynko, Iaroslava A ^d   Grigoryev, Sergei A ^d   Whisstock, James C ^a  

^a MONASH UNIVERSITY   (Australia)

^b PENN STATE COLLEGE OF MEDICINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CELLS; CONDENSATION; DEGRADATION;

NUCLEAR TRANSPORT;

PROTEINS;

CATHEPSIN L; CATHEPSIN V; CYSTEINE PROTEINASE; MYELOID AND ERYTHROID NUCLEAR TERMINATION STAGE SPECIFIC PROTEIN; PAPAIN; RETINOBLASTOMA PROTEIN; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIRD; BLOOD CELL; CELL PROLIFERATION; CHROMATIN CONDENSATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; GENE DELETION; GENE MUTATION; HETEROCHROMATIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; AVIAN PROTEINS; BASE SEQUENCE; CATHEPSINS; CELL DIVISION; CELL LINE; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; DNA PRIMERS; HYDROLYSIS; MICE; MOLECULAR SEQUENCE DATA; PAPAIN; PROTEIN CONFORMATION; RETINOBLASTOMA PROTEIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA; AVES; MAMMALIA;

EID: 0037066736     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108460200     Document Type: Article

References (50)