The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition

Biochemistry

Volumn 44, Issue 21, 2005, Pages 7757-7767

  Hwang, Shin Rong ^a   Stoka, Veronika ^b   Turk, Vito ^b   Hook, Vivian Y H ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JO EF STEFAN INSTITUTE   (Slovenia)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSS-CLASS INHIBITION; ELASTASE; MOLECULAR CLONING; PAPAIN;

CLONING; ENZYME INHIBITION; HYDROPHOBICITY; RATE CONSTANTS; STOICHIOMETRY; SUBSTRATES;

PROTEINS;

CATHEPSIN L; CYSTEINE PROTEINASE; ELASTASE; ENDOPIN 2C; PAPAIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CATTLE; DNA CLEAVAGE; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; GENE AMPLIFICATION; LIVER; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; STOICHIOMETRY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CATHEPSINS; CATTLE; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PANCREATIC ELASTASE; PAPAIN; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE PROTEINASE INHIBITORS; SERPINS; SUBSTRATE SPECIFICITY;

BOVINAE; EQUUS ASINUS;

EID: 19644394871     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050053z     Document Type: Article

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