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Volumn 78, Issue 6, 1998, Pages 833-839

Significance of plasminogen activator inhibitor 2 as a prognostic marker in primary lung cancer: Association of decreased plasminogen activator inhibitor 2 with lymph node metastasis

Author keywords

Lung cancer; Lymph node metastasis; Plasminogen activator inhibitor 2; Prognosis

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR 2; UROKINASE;

EID: 0031679213     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1998.588     Document Type: Article
Times cited : (46)

References (38)
  • 1
    • 0029833158 scopus 로고    scopus 로고
    • Molecular mechanisms governing tumour-necrosis-factor-mediated regulation of plasminogen activator inhibitor type-2 gene expression
    • Anthony ED, Shen Y, Ruegg M and Medcalf RL (1996) Molecular mechanisms governing tumour-necrosis-factor-mediated regulation of plasminogen activator inhibitor type-2 gene expression. Eur J Biochem 241: 93-100
    • (1996) Eur J Biochem , vol.241 , pp. 93-100
    • Anthony, E.D.1    Shen, Y.2    Ruegg, M.3    Medcalf, R.L.4
  • 2
    • 0025354463 scopus 로고
    • Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PA1-2 and subsequent effects on extracellular matrix degradation
    • Baker MS, Bleakley P, Woodrow GC and Doe F (1990) Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PA1-2 and subsequent effects on extracellular matrix degradation. Cancer Res 50: 4676-4684
    • (1990) Cancer Res , vol.50 , pp. 4676-4684
    • Baker, M.S.1    Bleakley, P.2    Woodrow, G.C.3    Doe, F.4
  • 3
    • 0023034044 scopus 로고
    • The receptor for urokinase-plasminogen activator
    • Blasi F, Stoppeli MP and Cubellis MV (1986) The receptor for urokinase-plasminogen activator. J Cell Biochem 32: 179-186
    • (1986) J Cell Biochem , vol.32 , pp. 179-186
    • Blasi, F.1    Stoppeli, M.P.2    Cubellis, M.V.3
  • 4
    • 0028127825 scopus 로고
    • Prognostic value of plasminogen activator (uPA) and plaminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas
    • Bouchet C, Spyratos F, Martin PM, Hacene K, Gentile A and Oglobine J (1994) Prognostic value of plasminogen activator (uPA) and plaminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas. Br J Cancer 69: 398-405
    • (1994) Br J Cancer , vol.69 , pp. 398-405
    • Bouchet, C.1    Spyratos, F.2    Martin, P.M.3    Hacene, K.4    Gentile, A.5    Oglobine, J.6
  • 5
    • 0025130717 scopus 로고
    • Plasminogen-activator inhibitor type 1 is a potent inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells
    • Cajot JF, Bamat J, Bergomelli GE, Kruithof EK, Medcalf RL, Testuz J and Sordat B (1990) Plasminogen-activator inhibitor type 1 is a potent inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells. Proc Natl Acd Sci USA 87: 6936-6943
    • (1990) Proc Natl Acd Sci USA , vol.87 , pp. 6936-6943
    • Cajot, J.F.1    Bamat, J.2    Bergomelli, G.E.3    Kruithof, E.K.4    Medcalf, R.L.5    Testuz, J.6    Sordat, B.7
  • 6
    • 0028090482 scopus 로고
    • Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies
    • Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Ainto G, Stoppelli MP and Salvatore M (1994) Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies. Cancer Res 54: 5445-5454
    • (1994) Cancer Res , vol.54 , pp. 5445-5454
    • Carriero, M.V.1    Franco, P.2    Del Vecchio, S.3    Massa, O.4    Botti, G.5    D'Ainto, G.6    Stoppelli, M.P.7    Salvatore, M.8
  • 7
    • 0025867052 scopus 로고
    • Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells
    • Cohen RL, Xi XP, Crewley CW, Lucas BK, Levinson AD and Schuman MA (1991) Effects of urokinase receptor occupancy on plasmin generation and proteolysis of basement membrane by human tumor cells. Blood 78: 479-487
    • (1991) Blood , vol.78 , pp. 479-487
    • Cohen, R.L.1    Xi, X.P.2    Crewley, C.W.3    Lucas, B.K.4    Levinson, A.D.5    Schuman, M.A.6
  • 8
    • 0007170020 scopus 로고
    • Multiple protein 4.1 isoforms produced by alternative splicing in human erythroid cells
    • Conboy JG, Chan J, Mohandas N and Kan YW (1988) Multiple protein 4.1 isoforms produced by alternative splicing in human erythroid cells. Proc Natl Acad Sci USA 85: 9062-9065
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9062-9065
    • Conboy, J.G.1    Chan, J.2    Mohandas, N.3    Kan, Y.W.4
  • 9
    • 0025273735 scopus 로고
    • Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1
    • Cubellis MV, Wun TC and Blasi F (1990) Receptor-mediated internalization and degradation of urokinase is caused by its specific inhibitor PAI-1. EMBO J 9: 1079-1085
    • (1990) EMBO J , vol.9 , pp. 1079-1085
    • Cubellis, M.V.1    Wun, T.C.2    Blasi, F.3
  • 13
    • 0025951467 scopus 로고
    • Plasminogen activation by receptor-bound urokinase
    • Ellis V and Dano K (1991) Plasminogen activation by receptor-bound urokinase. Semin Thromb Hemost 17: 194-200
    • (1991) Semin Thromb Hemost , vol.17 , pp. 194-200
    • Ellis, V.1    Dano, K.2
  • 16
    • 0023002645 scopus 로고
    • Degradation of glycoprotein and collagenous components of the basement membrane, studies with urokinase-type plasminogen activator, alfathrombin and plasmin
    • Goldfarb RH, Murano G, Brundage R, Siegal GP, Terranova V. Garbisa S and Liotta LA (1986) Degradation of glycoprotein and collagenous components of the basement membrane, studies with urokinase-type plasminogen activator, alfathrombin and plasmin. Thromb Hemostasis 12: 335-336
    • (1986) Thromb Hemostasis , vol.12 , pp. 335-336
    • Goldfarb, R.H.1    Murano, G.2    Brundage, R.3    Siegal, G.P.4    Terranova, V.5    Garbisa, S.6    Liotta, L.A.7
  • 17
    • 0028012079 scopus 로고
    • Dioxin-responsive genes, examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction
    • Heuvel JPV, Clark GC, Kohn MC, Tritscher AM, Greenlee WF, Lucier GW and Bell DA (1994) Dioxin-responsive genes, examination of dose-response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res 54: 62-68
    • (1994) Cancer Res , vol.54 , pp. 62-68
    • Heuvel, J.P.V.1    Clark, G.C.2    Kohn, M.C.3    Tritscher, A.M.4    Greenlee, W.F.5    Lucier, G.W.6    Bell, D.A.7
  • 18
    • 0026079414 scopus 로고
    • Urokinase-dependent proteolysis in cultured colon cancer is directed by its receptor
    • Hollas W and Boyd D (1991) Urokinase-dependent proteolysis in cultured colon cancer is directed by its receptor. Semin Thromb Hemost 17: 225-230
    • (1991) Semin Thromb Hemost , vol.17 , pp. 225-230
    • Hollas, W.1    Boyd, D.2
  • 19
    • 0029954446 scopus 로고    scopus 로고
    • Inverse correlation between mRNA expression of plasminogen activator inhibitor-2 and lymph node metastasis in human breast cancer
    • Ishikawa N, Endo Y and Sasaki T (1996) Inverse correlation between mRNA expression of plasminogen activator inhibitor-2 and lymph node metastasis in human breast cancer. Jpn J Cancer Res 87: 480-487
    • (1996) Jpn J Cancer Res , vol.87 , pp. 480-487
    • Ishikawa, N.1    Endo, Y.2    Sasaki, T.3
  • 20
    • 0024435761 scopus 로고
    • Functional characteristics of receptor-bound urokinase on human monocytes, catalytic efficiency and susceptibility to inactivation by plasminogen activation inhibitors
    • Kirchheimer JC and Remold HG (1989) Functional characteristics of receptor-bound urokinase on human monocytes, catalytic efficiency and susceptibility to inactivation by plasminogen activation inhibitors. Blood 74: 1396-1402
    • (1989) Blood , vol.74 , pp. 1396-1402
    • Kirchheimer, J.C.1    Remold, H.G.2
  • 21
    • 0027141760 scopus 로고
    • Inhibition of invasion of HT1080 sarcoma cells expressing recombinant plasminogen activator inhibitor 2
    • Laug WE, Cao XR, Yu YB, Shimada H and Kruithof EKO (1993)Inhibition of invasion of HT1080 sarcoma cells expressing recombinant plasminogen activator inhibitor 2. Cancer Res 53: 6051-6657
    • (1993) Cancer Res , vol.53 , pp. 6051-6657
    • Laug, W.E.1    Cao, X.R.2    Yu, Y.B.3    Shimada, H.4    Kruithof, E.K.O.5
  • 22
    • 0019850184 scopus 로고
    • Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane
    • Liotta LA, Goldfarb RH, Brundage R, Siegal GP, Terranova V and Garbisa S (1981) Effect of plasminogen activator (urokinase), plasmin, and thrombin on glycoprotein and collagenous components of basement membrane. Cancer Res 41: 4629-4636
    • (1981) Cancer Res , vol.41 , pp. 4629-4636
    • Liotta, L.A.1    Goldfarb, R.H.2    Brundage, R.3    Siegal, G.P.4    Terranova, V.5    Garbisa, S.6
  • 23
    • 0029979717 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor type 2 gene induction by tumor necrosis factor and phorbol ester involves transcriptional and post-transcriptional events, identification of a functional nonameric AU-rich motif in the 3′-untranslated region
    • Maurer F and Medcalf RL (1996) Plasminogen activator inhibitor type 2 gene induction by tumor necrosis factor and phorbol ester involves transcriptional and post-transcriptional events, identification of a functional nonameric AU-rich motif in the 3′-untranslated region. J Biol Chem 271: 26074-26080
    • (1996) J Biol Chem , vol.271 , pp. 26074-26080
    • Maurer, F.1    Medcalf, R.L.2
  • 24
    • 0028919172 scopus 로고
    • Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice
    • Mueller BM, Yu YB and Laug WE (1995) Overexpression of plasminogen activator inhibitor 2 in human melanoma cells inhibits spontaneous metastasis in scid/scid mice. Proc Natl Acad Sci USA 92: 205-209
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 205-209
    • Mueller, B.M.1    Yu, Y.B.2    Laug, W.E.3
  • 25
    • 0028325321 scopus 로고
    • Plasminogen activators and their inhibitors in non-small cell lung cancer, low content of type 2 plasminogen activator inhibitor associated with tumor dissemination
    • Nagayama M, Sato A, Hayakawa H, Urano T, Takada Y and Takada A (1994) Plasminogen activators and their inhibitors in non-small cell lung cancer, low content of type 2 plasminogen activator inhibitor associated with tumor dissemination. Cancer 73: 1398-1405
    • (1994) Cancer , vol.73 , pp. 1398-1405
    • Nagayama, M.1    Sato, A.2    Hayakawa, H.3    Urano, T.4    Takada, Y.5    Takada, A.6
  • 26
    • 0028812299 scopus 로고
    • Localization of urokinase-type plasminogen activator inhibitor-1,2 and plasminogen in colon cancer
    • Naitoh H, Eguchi Y, Ueyama H, Kodama M and Hattori T (1995)Localization of urokinase-type plasminogen activator inhibitor-1,2 and plasminogen in colon cancer. Jpn J Cancer Res 86: 48-56
    • (1995) Jpn J Cancer Res , vol.86 , pp. 48-56
    • Naitoh, H.1    Eguchi, Y.2    Ueyama, H.3    Kodama, M.4    Hattori, T.5
  • 27
    • 0022549709 scopus 로고
    • Plasminogen activators catalyze conversion of inhibitor from fibrosarcoma cells to an inactive form with a lower apparent molecular mass
    • Nielsen LS, Andreasen PA, Grondahl-Hansen J, Skriver L and Dano K (1986) Plasminogen activators catalyze conversion of inhibitor from fibrosarcoma cells to an inactive form with a lower apparent molecular mass. FEBS Lett 196: 269-273
    • (1986) FEBS Lett , vol.196 , pp. 269-273
    • Nielsen, L.S.1    Andreasen, P.A.2    Grondahl-Hansen, J.3    Skriver, L.4    Dano, K.5
  • 28
    • 0030038857 scopus 로고    scopus 로고
    • Relationship between expression of plasminogen activator system and metastatic ability in human cancers
    • Noguchi-Takino M, Endo Y, Yonemura Y and Sasaki T (1996) Relationship between expression of plasminogen activator system and metastatic ability in human cancers. Int J Oncol 8: 97-105
    • (1996) Int J Oncol , vol.8 , pp. 97-105
    • Noguchi-Takino, M.1    Endo, Y.2    Yonemura, Y.3    Sasaki, T.4
  • 29
    • 0026804627 scopus 로고
    • Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor
    • Olson D, Pöllänen J, Hoyer-Hansen G, Ronne E, Sakaguchi K and Wun TC (1992) Internalization of the urokinase-plasminogen activator inhibitor type-1 complex is mediated by the urokinase receptor. J Biol Chem 267: 9129-9133
    • (1992) J Biol Chem , vol.267 , pp. 9129-9133
    • Olson, D.1    Pöllänen, J.2    Hoyer-Hansen, G.3    Ronne, E.4    Sakaguchi, K.5    Wun, T.C.6
  • 30
    • 0024238269 scopus 로고
    • In vivo invasion of modified chorioallantoic membrane by tumor cells: The role of cell surface-bound urokinase
    • Ossowski L (1988) In vivo invasion of modified chorioallantoic membrane by tumor cells: the role of cell surface-bound urokinase. J Cell Biol 107: 2437-2445
    • (1988) J Cell Biol , vol.107 , pp. 2437-2445
    • Ossowski, L.1
  • 31
    • 0025234559 scopus 로고
    • Pro-urokinase activation on the surface of human rhabdomyosarcoma cells, localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class 2 plasminogen activator inhibitor
    • Pöllänen J, Vaheri A, Tapiovaara H, Riley E, Bertram K and Woodrew G (1990) Pro-urokinase activation on the surface of human rhabdomyosarcoma cells, localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class 2 plasminogen activator inhibitor. Proc Natl Acad Sci USA 87: 2230-2234
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2230-2234
    • Pöllänen, J.1    Vaheri, A.2    Tapiovaara, H.3    Riley, E.4    Bertram, K.5    Woodrew, G.6
  • 32
    • 0025945850 scopus 로고
    • Directed plasminogen activation at the surface of normal and malignant cells
    • Pöllänen J, Stephenes RW and Vaheri A (1991) Directed plasminogen activation at the surface of normal and malignant cells. Adv Cancer Res 57: 273-328
    • (1991) Adv Cancer Res , vol.57 , pp. 273-328
    • Pöllänen, J.1    Stephenes, R.W.2    Vaheri, A.3
  • 33
    • 0025853770 scopus 로고
    • Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasion foci in human colon adenocarcinomas
    • Pyke C, Kristensen P, Raltkiaer E, Grondahl-Hansen J and Brasi F (1991) Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasion foci in human colon adenocarcinomas. Am J Pathol 138: 1059-1067
    • (1991) Am J Pathol , vol.138 , pp. 1059-1067
    • Pyke, C.1    Kristensen, P.2    Raltkiaer, E.3    Grondahl-Hansen, J.4    Brasi, F.5
  • 34
    • 0014216684 scopus 로고
    • The peptide chains of human plasmin, mechanism of activation system of human plasminogen to plasmin
    • Robbins KC, Summaria L, Hsieh B and Shah RJ (1967) The peptide chains of human plasmin, mechanism of activation system of human plasminogen to plasmin. J Biol Chem 242: 2333-2342
    • (1967) J Biol Chem , vol.242 , pp. 2333-2342
    • Robbins, K.C.1    Summaria, L.2    Hsieh, B.3    Shah, R.J.4
  • 35
    • 0020431191 scopus 로고
    • Secretion of basement membrane collagen degrading enzyme and plasminogen activator by transformed cells - Role in metastasis
    • Salo T, Liotta LA, Keski-Oja J, Turpeenniem-Hujanen T and Tryggvason K (1982) Secretion of basement membrane collagen degrading enzyme and plasminogen activator by transformed cells - role in metastasis. Int J Cancer 30: 669-673
    • (1982) Int J Cancer , vol.30 , pp. 669-673
    • Salo, T.1    Liotta, L.A.2    Keski-Oja, J.3    Turpeenniem-Hujanen, T.4    Tryggvason, K.5
  • 36
    • 0025610853 scopus 로고
    • The role of urokinase-type plasminogen activator in aggressive tumor cell behavior
    • Testa JE and Quigley JP (1990) The role of urokinase-type plasminogen activator in aggressive tumor cell behavior. Cancer Metastasis Rev 9: 353-367
    • (1990) Cancer Metastasis Rev , vol.9 , pp. 353-367
    • Testa, J.E.1    Quigley, J.P.2
  • 38
    • 0025323133 scopus 로고
    • Urokinase receptors in lung cancer and normal lung
    • Veale D, Needham G and Harris AL (1990) Urokinase receptors in lung cancer and normal lung. Anticancer Res 10: 417-422
    • (1990) Anticancer Res , vol.10 , pp. 417-422
    • Veale, D.1    Needham, G.2    Harris, A.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.