Characterization of substrate specificity of dog CYP1A2 using CYP1A2-deficient and wild-type dog liver microsomes

Drug Metabolism and Disposition

Volumn 36, Issue 9, 2008, Pages 1903-1908

  Mise, Masashi ^a   Hashizume, Takanori ^a   Komuro, Setsuko ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

9 CIS RETINAL OXIDASE; AMINOPYRINE N DEMETHYLASE; BUFURALOL; BUFURALOL 1' HYDROXYLASE; CAFFEINE; CYTOCHROME P450 1A2; ESTRADIOL 2 HYDROXYLASE; ETHOXYRESORUFIN DEETHYLASE; MELATONIN 6 HYDROXYLASE; MIDAZOLAM; MIDAZOLAM 1' HYDROXYLASE; PHENACETIN O DEETHYLASE; TACRINE; TACRINE 1 HYDROXYLASE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOG; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME ASSAY; ENZYME METABOLISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; GENOTYPE; HUMAN; HUMAN CELL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

ANIMALS; BASE SEQUENCE; CYTOCHROME P-450 CYP1A2; DNA PRIMERS; DOGS; HUMANS; MICROSOMES, LIVER; POLYMERASE CHAIN REACTION; SUBSTRATE SPECIFICITY;

CANIS FAMILIARIS;

EID: 50049103631     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.108.022301     Document Type: Article

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