-
1
-
-
0032945691
-
A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans
-
Nunoya KI, Yokoi T, Kimura K, Kainuma T, Satoh K, Kinoshita M, et al. A new CYP2A6 gene deletion responsible for the in vivo polymorphic metabolism of (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride in humans. J Pharmacol Exp Ther 1999; 289:437-442.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 437-442
-
-
Nunoya, K.I.1
Yokoi, T.2
Kimura, K.3
Kainuma, T.4
Satoh, K.5
Kinoshita, M.6
-
2
-
-
0029658591
-
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism
-
Sullivan-Klose TH, Ghanayem BI, Bell DA, Zhang ZY, Kaminsky LS, Shenfield GM, et al. The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism. Pharmacogenetics 1996; 6:341-349.
-
(1996)
Pharmacogenetics
, vol.6
, pp. 341-349
-
-
Sullivan-Klose, T.H.1
Ghanayem, B.I.2
Bell, D.A.3
Zhang, Z.Y.4
Kaminsky, L.S.5
Shenfield, G.M.6
-
3
-
-
0028260641
-
The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
-
de Morais SM, Wilkinson GR, Blaisdell J, Nakamura K, Meyer UA, Goldstein JA. The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J Biol Chem 1994; 269:15419-15422.
-
(1994)
J Biol Chem
, vol.269
, pp. 15419-15422
-
-
De Morais, S.M.1
Wilkinson, G.R.2
Blaisdell, J.3
Nakamura, K.4
Meyer, U.A.5
Goldstein, J.A.6
-
4
-
-
0025036544
-
Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes
-
Kagimoto M, Heim M, Kagimoto K, Zeugin T, Meyer UA. Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes. J Biol Chem 1990; 265:17209-17214.
-
(1990)
J Biol Chem
, vol.265
, pp. 17209-17214
-
-
Kagimoto, M.1
Heim, M.2
Kagimoto, K.3
Zeugin, T.4
Meyer, U.A.5
-
5
-
-
0012304444
-
Interindividual variation of P450 enzymes in vitro and its causes
-
Pacifici GM, Pelkonen O, editors. London: Taylor & Francis
-
Pelkonen O, Boobis AR, Kremers P, Ingelman-Sundberg M, Rane A. Interindividual variation of P450 enzymes in vitro and its causes. In: Pacifici GM, Pelkonen O, editors. Interindividual Variability in Human Drug Metabolism. London: Taylor & Francis; 2001. pp. 269-332.
-
(2001)
Interindividual Variability in Human Drug Metabolism
, pp. 269-332
-
-
Pelkonen, O.1
Boobis, A.R.2
Kremers, P.3
Ingelman-Sundberg, M.4
Rane, A.5
-
6
-
-
0032853122
-
Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib
-
Paulson SK, Engel L, Reitz B, Bolten S, Burton EG, Maziasz TJ, et al. Evidence for polymorphism in the canine metabolism of the cyclooxygenase 2 inhibitor, celecoxib. Drug Metab Dispos 1999; 27:1133-1142.
-
(1999)
Drug Metab Dispos
, vol.27
, pp. 1133-1142
-
-
Paulson, S.K.1
Engel, L.2
Reitz, B.3
Bolten, S.4
Burton, E.G.5
Maziasz, T.J.6
-
7
-
-
0031892910
-
Isolation of a new canine cytochrome P450 cDNA from the cytochrome P450 2C subfamily (CYP2C41) and evidence for polymorphic differences in its expression
-
Blaisdell J, Goldstein JA, Bai SA. Isolation of a new canine cytochrome P450 cDNA from the cytochrome P450 2C subfamily (CYP2C41) and evidence for polymorphic differences in its expression. Drug Metab Dispos 1998; 26:278-283.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 278-283
-
-
Blaisdell, J.1
Goldstein, J.A.2
Bai, S.A.3
-
8
-
-
0032169478
-
Expression and characterization of canine cytochrome P450 2D15
-
Roussel F, Duignan DB, Lawton MP, Obach RS, Strick CA, Tweedie DJ. Expression and characterization of canine cytochrome P450 2D15. Arch Biochem Biophys 1998; 357:27-36.
-
(1998)
Arch Biochem Biophys
, vol.357
, pp. 27-36
-
-
Roussel, F.1
Duignan, D.B.2
Lawton, M.P.3
Obach, R.S.4
Strick, C.A.5
Tweedie, D.J.6
-
9
-
-
0033860015
-
Cloning of canine cytochrome P450 2E1 cDNA: Identification and characterization of two variant alleles
-
Lankford SM, Bai SA, Goldstein JA. Cloning of canine cytochrome P450 2E1 cDNA: identification and characterization of two variant alleles. Drug Metab Dispos 2000; 28:981-986.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 981-986
-
-
Lankford, S.M.1
Bai, S.A.2
Goldstein, J.A.3
-
10
-
-
0842282544
-
Polymorphic expression of CYP1A2 leading to interindividual variability in metabolism of a novel benzodiazepine receptor partial inverse agonist in dogs
-
Mise M, Yadera S, Matsuda M, Hashizume T, Matsumoto S, Terauchi Y, et al. Polymorphic expression of CYP1A2 leading to interindividual variability in metabolism of a novel benzodiazepine receptor partial inverse agonist in dogs. Drug Metab Dispos 2004; 32:240-245.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 240-245
-
-
Mise, M.1
Yadera, S.2
Matsuda, M.3
Hashizume, T.4
Matsumoto, S.5
Terauchi, Y.6
-
11
-
-
0025223054
-
Isolation of cDNAs coding for three different forms of liver microsomal cytochrome P-450 from polychlorinated biphenyl-treated beagle dogs
-
Uchida T, Komori M, Kitada M, Kamataki T. Isolation of cDNAs coding for three different forms of liver microsomal cytochrome P-450 from polychlorinated biphenyl-treated beagle dogs. Mol Pharmacol 1990; 38:644-651.
-
(1990)
Mol Pharmacol
, vol.38
, pp. 644-651
-
-
Uchida, T.1
Komori, M.2
Kitada, M.3
Kamataki, T.4
-
12
-
-
0024445437
-
Human CYP1A2: Sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression
-
Ikeya K, Jaiswal AK, Owens RA, Jones JE, Nebert DW, Kimura S. Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression. Mol Endocrinol 1989; 3:1399-1408.
-
(1989)
Mol Endocrinol
, vol.3
, pp. 1399-1408
-
-
Ikeya, K.1
Jaiswal, A.K.2
Owens, R.A.3
Jones, J.E.4
Nebert, D.W.5
Kimura, S.6
-
14
-
-
0036842968
-
In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs
-
Graham RA, Downey A, Mudra D, Krueger L, Carroll K, Chengelis C, et al. In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs. Drug Metab Dispos 2002; 30:1206-1213.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1206-1213
-
-
Graham, R.A.1
Downey, A.2
Mudra, D.3
Krueger, L.4
Carroll, K.5
Chengelis, C.6
-
15
-
-
0030834058
-
Human cytochrome P450 enzymes: A status report summarizing their reactions, substrates, inducers, and inhibitors
-
Rendic S, Di Carlo FJ. Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors. Drug Metab Rev 1997; 29:413-580.
-
(1997)
Drug Metab Rev
, vol.29
, pp. 413-580
-
-
Rendic, S.1
Di Carlo, F.J.2
-
16
-
-
0025374597
-
Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s
-
Aoyama T, Korzekwa K, Nagata K, Gillette J, Gelboin HV, Gonzalez FJ. Estradiol metabolism by complementary deoxyribonucleic acid-expressed human cytochrome P450s. Endocrinology 1990; 126:3101-3106.
-
(1990)
Endocrinology
, vol.126
, pp. 3101-3106
-
-
Aoyama, T.1
Korzekwa, K.2
Nagata, K.3
Gillette, J.4
Gelboin, H.V.5
Gonzalez, F.J.6
-
17
-
-
0026451998
-
Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes
-
Kerlan V, Dreano Y, Bercovici JP, Beaune PH, Floch HH, Berthou F. Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes. Biochem Pharmacol 1992; 44:1745-1756.
-
(1992)
Biochem Pharmacol
, vol.44
, pp. 1745-1756
-
-
Kerlan, V.1
Dreano, Y.2
Bercovici, J.P.3
Beaune, P.H.4
Floch, H.H.5
Berthou, F.6
-
18
-
-
0031830896
-
Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes
-
Yamazaki H, Shaw PM, Guengerich FP, Shimada T. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes. Chem Res Toxicol 1998; 11:659-665.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 659-665
-
-
Yamazaki, H.1
Shaw, P.M.2
Guengerich, F.P.3
Shimada, T.4
-
19
-
-
0034129702
-
Fluvoxamine but not citalopram increases serum melatonin in healthy subjects - An indication that cytochrome P450 CYP1A2 and CYP2C19 hydroxylate melatonin
-
von Bahr C, Ursing C, Yasui N, Tybring G, Bertilsson L, Rojdmark S. Fluvoxamine but not citalopram increases serum melatonin in healthy subjects - an indication that cytochrome P450 CYP1A2 and CYP2C19 hydroxylate melatonin. Eur J Clin Pharmacol 2000; 56:123-127.
-
(2000)
Eur J Clin Pharmacol
, vol.56
, pp. 123-127
-
-
Von Bahr, C.1
Ursing, C.2
Yasui, N.3
Tybring, G.4
Bertilsson, L.5
Rojdmark, S.6
-
20
-
-
0035293495
-
Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes
-
Facciola G, Hidestrand M, von Bahr C, Tybring G. Cytochrome P450 isoforms involved in melatonin metabolism in human liver microsomes. Eur J Clin Pharmacol 2001; 56:881-888.
-
(2001)
Eur J Clin Pharmacol
, vol.56
, pp. 881-888
-
-
Facciola, G.1
Hidestrand, M.2
Von Bahr, C.3
Tybring, G.4
-
21
-
-
0029071846
-
Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2
-
Pineau T, Fernandez-Salguero P, Lee SS, McPhail T, Ward JM, Gonzalez FJ. Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2. Proc Natl Acad Sci U S A 1995; 92:5134-5138.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5134-5138
-
-
Pineau, T.1
Fernandez-Salguero, P.2
Lee, S.S.3
McPhail, T.4
Ward, J.M.5
Gonzalez, F.J.6
-
22
-
-
0029867020
-
Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism
-
Liang HC, Li H, McKinnon RA, Duffy JJ, Potter SS, Puga A, et al. Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism. Proc Natl Acad Sci U S A 1996; 93:1671-1676.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 1671-1676
-
-
Liang, H.C.1
Li, H.2
McKinnon, R.A.3
Duffy, J.J.4
Potter, S.S.5
Puga, A.6
-
23
-
-
0037838823
-
Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse
-
Smith AG, Davies R, Dalton TP, Miller ML, Judah D, Riley J, et al. Intrinsic hepatic phenotype associated with the Cyp1a2 gene as shown by cDNA expression microarray analysis of the knockout mouse. EHP Toxicogenomics 2003; 111:45-51.
-
(2003)
EHP Toxicogenomics
, vol.111
, pp. 45-51
-
-
Smith, A.G.1
Davies, R.2
Dalton, T.P.3
Miller, M.L.4
Judah, D.5
Riley, J.6
-
24
-
-
0042820015
-
Identification of a novel splice-site mutation in the CYP1A2 gene
-
Allorge D, Chevalier D, Lo-Guidice JM, Cauffiez C, Suard F, Baumann P, et al. Identification of a novel splice-site mutation in the CYP1A2 gene. Br J Clin Pharmacol 2003; 56:341-344.
-
(2003)
Br J Clin Pharmacol
, vol.56
, pp. 341-344
-
-
Allorge, D.1
Chevalier, D.2
Lo-Guidice, J.M.3
Cauffiez, C.4
Suard, F.5
Baumann, P.6
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