Lower phosphoinositide 3-kinase (PI 3-kinase) activity and differential expression levels of selective catalytic and regulatory PI 3-kinase subunit isoforms in prefrontal cortex and hippocampus of suicide subjects

Neuropsychopharmacology

Volumn 33, Issue 10, 2008, Pages 2324-2340

  Dwivedi, Yogesh ^a   Rizavi, Hooriyah S ^a   Teppen, Tara ^a   Zhang, Hui ^a   Mondal, Amal ^a   Roberts, Rosalinda C ^b   Conley, Robert R ^c   Pandey, Ghanshyam N ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c MARYLAND PSYCHIATRIC RESEARCH CENTER   (United States)

Author keywords

Depression; Gene expression; Human postmortem brain; Immunolabeling; PI 3 kinase; Suicide

Indexed keywords

MESSENGER RNA; NEUROTROPHIC FACTOR; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P110; PROTEIN P110 BETA; PROTEIN P110ALPHA; PROTEIN P85; PROTEIN P85ALPHA; PROTEIN P85BETA; PROTEIN TYROSINE KINASE A; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; NERVE CELL PLASTICITY; POLYMERASE CHAIN REACTION; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUICIDE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADULT; AGED; AGED, 80 AND OVER; CATALYTIC DOMAIN; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HIPPOCAMPUS; HUMANS; ISOENZYMES; MALE; MIDDLE AGED; MOLECULAR WEIGHT; MOOD DISORDERS; PREFRONTAL CORTEX; PROTEIN SUBUNITS; RNA, MESSENGER; SUICIDE;

EID: 49549121134     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301641     Document Type: Article

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