Targeting the tetraspanin CD81 blocks monocyte transmigration and ameliorates EAE

Neurobiology of Disease

Volumn 31, Issue 3, 2008, Pages 413-421

  Dijkstra, S ^a,c   Kooij, G ^a   Verbeek, R ^c   van der Pol, S M A ^a   Amor, S ^a   Geisert Jr , E E ^b   Dijkstra, C D ^a   van Noort, J M ^c   Vries, H E de ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c TNO   (Netherlands)

Author keywords

CD81; EAE; Multiple sclerosis; Tetraspanins; Therapeutic antibodies; Transendothelial migration

Indexed keywords

CD81 ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1 3 3 22; MONOCLONAL ANTIBODY 1D6; MONOCLONAL ANTIBODY 2F7; MONOCLONAL ANTIBODY AMP1; MONOCLONAL ANTIBODY CD81; MONOCLONAL ANTIBODY EAT2; MONOCLONAL ANTIBODY JS81; MONOCLONAL ANTIBODY TA2; TETRASPANIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 4 ANTIBODY;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; MONOLAYER CULTURE; MOUSE; MYELITIS; NEUROLOGIC DISEASE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RAT; TREATMENT OUTCOME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; BLOOD-BRAIN BARRIER; CELL LINE, TRANSFORMED; CEREBRAL ARTERIES; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; ENDOTHELIAL CELLS; FEMALE; HUMANS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE AGENTS; MICE; MONOCYTES; MULTIPLE SCLEROSIS; RATS; TREATMENT OUTCOME;

EID: 49449102743     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.05.018     Document Type: Article

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