Negative regulation of FcεRI-mediated degranulation by CD81

Journal of Experimental Medicine

Volumn 186, Issue 8, 1997, Pages 1307-1314

  Fleming, Tony J ^a   Donnadieu, Emmanuel ^a   Song, Chang Ho ^a   Van Laethem, Francois ^a,b   Galli, Stephen J ^a   Kinet, Jean Pierre ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; ANTIGEN; CALCIUM; CD81 ANTIGEN; FC RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; LEUKOTRIENE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; PHOSPHATASE; PROTEIN TYROSINE KINASE; TYROSINE;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; ENZYME IMMUNOASSAY; FLOW CYTOMETRY; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOBLOTTING; MAST CELL; MAST CELL DEGRANULATION; NONHUMAN; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SKIN ANAPHYLAXIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; CELL DEGRANULATION; CLONING, MOLECULAR; DOWN-REGULATION; IMMUNOGLOBULIN E; LEUKEMIA, BASOPHILIC, ACUTE; MALE; MAST CELLS; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; PASSIVE CUTANEOUS ANAPHYLAXIS; PEPTIDES; RATS; RATS, WISTAR; RECEPTORS, IGE; TUMOR CELLS, CULTURED;

EID: 0030728260     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.186.8.1307     Document Type: Article

References (57)

1. Jouvin, M.-H., M. Adamczewski, R. Numerof, O. Letourneur, A. Valle, and J.-P. Kinet. 1994. Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor. J. Biol. Chem. 269:5918-5925.
2. Penhallow, R.C., K. Class, H. Sonoda, J.B. Bolen, and R.B. Rowley. 1995. Temporal activation of nontransmembrane protein-tyrosine kinases following mast cell Fc epsilonRI engagement. J. Biol. Chem. 270:23362-23365.
3. Scharenberg, A.M., S. Lin, B. Cuenod, H. Yamamura, and J.-P. Kinet. 1995. Reconstitution of interactions between tyrosine kinases and the high affinity IgE receptor are controlled by receptor clustering. EMBO (Eur. Mol. Biol. Organ.) J. 14:3385-3394.
4. Lin, S., C. Cicala, A.M. Scharenberg, and J.-P. Kinet. 1996. The Fc∈RIβ subunit functions as an amplifier of Fc∈RIγ-mediated cell activation signals. Cell. 85:985-995.
5. Paul, W.E., R.A. Seder, and M. Plaut. 1993. Lymphokine and cytokine production by Fc∈RI+ cells. Adv. Immunol. 53: 1-29.
6. Kawakami, Y., L. Yao, T. Mirua, S. Tsukada. O.N. Witte, and T. Kawakami. 1994. Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc∈RI cross-linking. Mol. Cell. Biol. 14:5108-5113.
7. Kawakami, Y., L. Yao, M. Tashiro, S. Gibson, G.B. Mills, and T. Kawakami. 1995. Activation and interaction with protein kinase C of a cytoplasmic tyrosine kinase, Itk/Tsk/ Emt, on Fc epsilon RI cross-linking on mast cells. J. Immunol. 155:3556-3562.
8. Hamawy, M.M., S.E. Mergenhagen, and R.P. Siraganian. 1993. Tyrosine phosphorylation of pp125FAK by the aggregation of high affinity immunoglobulin E receptors requires cell adherence. J. Biol. Chem. 268:6851-6854.
9. 2+ and purified isozymes in washed permeabilized cells. J. Biol. Chem. 268:1749-1756.
10. Hirasawa, N., A. Scharenberg, H. Yamamura, M.A. Beaven, and J.-P. Kinet. 1995. A requirement for syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor. J. Biol. Chem. 270:10960-10967.
11. Ota, Y., L.O. Beitz, A.M. Scharenberg, J.A. Donovan, J.-P. Kinet, and L.E. Samelson. 1996. Characterization of cbl tyrosine phosphorylation and a cbl-syk complex in RBL-2H3 cells. J. Exp. Med. 184:1713-1723.
12. Jabril-Cuenod, B., C. Zhang, A.M. Scharenberg, R. Paolini, R. Numerof, M.A. Beaven, and J.-P. Kinet. 1996. Syk-dependent phosphorylation of Shc. A potential link between Fc∈RI and the ras/mitogen-activated protein kinase signaling pathway through Sos and Grb2. J. Biol. Chem. 271:16268-16272.
13. Flaswinkel, H., M. Barner, and M. Reth. 1995. The tyrosine actrivation motif as a target of protein tyrosine kinases and SH2 domains. Semin. Immunol. 7:21-27.
14. Cambier, J.C. 1995. Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM). J. Immunol. 155:3281-3285.
15. Johnson, S.A., C.M. Pleiman, L. Pao, J. Schneringer, K. Hippen, and J.C. Cambier. 1995. Phosphorylated immunoreceptor signaling motifs (ITAMs) exhibit unique abilities to bind and activate Lyn and Syk tyrosine kinases. J. Immunol. 155: 4596-4603.
16. Kimura, T., H. Kihara, S. Bhattacharyya, H. Sakamoto, E. Appella, and R.P. Siraganian. 1996. Downstream signaling molecules bind to different phosphorylated immunoreceptor tyrosine-based activation motif (ITAM) peptides of the high affinity IgE receptor. J. Biol. Chem. 271:27962-27968.
17. Zhang, J., E.H. Berenstein, R.L. Evans, and R.P. Siraganian. 1996. Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells. J. Exp. Med. 184:71-79.
18. Taylor, J.A., J.L. Karas, M.K. Ram, O.M. Green, and C. Seidel-Dugan. 1995. Activation of the high affinity immunoglobulin E receptor Fc∈RI in RBL-2H3 cells is inhibited by syk SH2 domains. Mol. Cell. Biol. 15:4149-4157.
19. Scharenberg, A.M., and J.-P. Kinet. 1996. The emerging field of receptor mediated inhibitory signaling: SHP or SHIP? Cell. 87:961-964.
20. Cambier, J.C. 1997. Inhibitory receptors abound? Proc. Natl. Acad. Sci. USA. 94:5993-5995.
21. Ono, M., S. Bolland, P. Tempst, and J.V. Ravetch. 1996. Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB. Nature (Lond.). 383:263-266.
22. Gupta, N., A.M. Scharenberg, D.N. Burshtyn, N. Wagtmann, M.N. Lioubin, L.R. Rorhschneider, J.-P. Kinet, and E.O. Long. 1997. Negative signaling pathways of the killer cell inhibitory receptor and FcγRIIb1 require distinct phosphatases. J. Exp. Med. 186:473-478.
23. Burshtyn, D.N., A.M. Scharenberg, N. Wagtmann, S. Rajagopalan, K. Berrada, T. Yi, J.-P. Kinet, and E.O. Long. 1996. Recruitment of tyrosine phosphatase HCP by the killer cell inhibitory receptor. Immunity. 4:77-85.
24. Binstadt, B.A., K.M. Brumbaugh, C.J. Dick, A.M. Scharenberg, B.L. Williams, M. Colonna, L.L. Lanier, J.-P. Kinet, R.T. Abraham, and P.J. Leibson. 1996. Sequential involvement of Lck and SHP-1 with MHC-recognizing receptors on NK cells inhibits FcR-initiated tyrosine kinase activation. Immunity. 5:629-638.
25. Young, J.D.-E., C.-C. Liu, G. Butler, Z.A. Cohn, and S.J. Galli. 1987. Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor. Proc. Natl. Acad. Sci. USA. 84:9175-9179.
26. Paolini, R., M.-H. Jouvin, and J.-P. Kinet. 1991. Phosphorylation and dephosphorylation of the high-affinity receptor for immunoglobulin E immediately after receptor engagement and disengagement. Nature (Lond.). 353:855-858.
27. Daëron, M., C. Bonnerot, S. Latour, and W.H. Fridman. 1992. Murine recombinant FcγRIII, but not FcγRII, trigger serotonin release in rat basophilic leukemia cells. J. Immunol. 149:1365-1373.
28. Ortega Soto, E., and I. Pecht. 1988. A monoclonal antibody that inhibits secretion from rat basophilic leukemia cells and binds to a novel membrane component. J. Immunol. 141: 4324-4332.
29. Geisert, E.E., Jr., T.P. Murphy, M.H. Irwin, and H. Larjava. 1991. A novel cell adhesion molecule, G-CAM, found on cultured rat glia. Neurosci. Lett. 133:262-266.
30. Irwin, M.H., and E.E. Geisert, Jr. 1993. The upregulation of a glial cell surface antigen at the astrocytic scar in the rat. Neurosci. Lett. 154:57-60.
31. Geisert, E.E., Jr., L. Yang, and M.H. Irwin. 1996. Astrocyte growth, reactivity, and the target of the antiproliferative antibody. TAPA. J. Neurosci. 16:5478-5487.
32. Dombrowicz, D., V. Flamand, I. Miyajima, J.V. Ravetch, S.J. Galli, and J.-P. Kinet. 1997. Absence of Fc∈RI alpha chain results in upregulation of FcγRIII-dependent mast cell degranulation and anaphylaxis. Evidence of competition between Fc∈RI and FcγRIII for limiting amounts of FcR β and γ chains. J. Clin. Invest. 99:915-925.
33. Wright, M.D., and M.G. Tomlinson. 1994. The ins and outs of the transmembrane 4 superfamily. Immunol. Today. 15: 588-594.
34. Fearon, D.T., and R.H. Carter. 1995. The CD19/CD2/ TAPA-1 complex of B lymphocytes: linking natural to acquired immunity. Annu. Rev. Immunol. 13:127-149.
35. Behr, S., and F. Schriever. 1995. Engaging CD19 or target of antiproliferative antibody 1 on human B lymphocytes induces binding of B cells to the interfollicular stroma of human tonsils via integrin α4/β1 and fibronectin. J. Exp. Med. 182: 1191-1199.
36. Maecker, H.T., and S. Levy. 1997. Normal lymphocyte development but delayed humoral immune response in CD81-null mice. J. Exp. Med. 185:1505-1510.
37. Secrist, H., S. Levy, R.H. DeKruyff, and D.T. Umetsu. 1996. Ligation of TAPA-1 (CD81) or major histocompatibility complex class II in co-cultures of human B and T lymphocytes enhances interleukin-4 synthesis by antigen-specific CD4+ T cells. Eur. J. Immunol. 26:1435-1442.
38. Todd, S.C., S.G. Lipps, L. Crisa, D.R. Saloman, and C.D. Tsoukas. 1996. CD81 expressed on human thymocytes mediates integrin activation and interleukin-2-dependent proliferation. J. Exp. Med. 184:2055-2060.
39. Oren, R., S. Takahashi, C. Doss, R. Levy, and S. Levy. 1990. TAPA-1, the target of an antiproliterative antibody, defines a new family of transmembrane proteins. Mol. Cell. Biol. 10:4007-4015.
40. Boismenu, R., M. Rhein, W.H. Fischer, and W.L. Havran. 1996. A role for CD81 in early T cell development. Science (Wash. DC). 271:198-200.
41. Imai, T., M. Kakizaki, M. Nishimura, and O. Yoshie. 1995. Molecular analysis of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82. J. Immunol. 155:1229-1239.
42. Angelisova, P., I. Hilgert, and V. Horejsi. 1994. Association of four antigens of the tetraspan family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins. Immunogenetics. 39:249-256.
43. Mannion, B.A., F. Berditchevski, S.K. Kraeft, L.B. Chen, and M.E. Hemler. 1996. Transmembrane-4 superfamily proteins CD81 (TAPA-1), CD82, CD63, and CD53 specifically associated with integrin α4 β1 (CD49d/CD29). J. Immunol. 157:2039-2047.
44. Berditchevski, F., K.F. Tolias, K. Wong, C.L. Carpenter, and M.E. Hemler. 1997. A novel link between integrins, transmembrane-4 superfamily proteins (CD63 and CD81), and phosphatidylinositol 4-kinase. J. Biol. Chem. 272:2595-2598.
45. Schick, M.R., V.Q. Nguyen, and S. Levy. 1993. Anti-TAPA-1 antibodies induce protein tyrosine phosphorylation that is prevented by increasing intracellular thiol levels. J. Immunol. 151:1918-1925.
46. 2+-sensitive cytosolic phospholipase A2 in MCII mast cells mediated by high-affinity Fc receptor for IgE. Biochem. J. 304: 923-928.
47. Ali, A., A.W. Ford-Hutchinson, and D.W. Nicholson. 1994. Activation of protein kinase C down-regulates and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells. J. Immunol. 153:776-788.
48. Marengere, L.E., P. Waterhouse, G.S. Duncan, H.W. Mittrucker, G.S. Feng, and T.W. Mak. 1996. Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science (Wash. DC). 272:1170-1173.
49. Law, C.L., S.P. Sidorenko, K.A. Chandran, Z. Zhao, S.H. Shen, E.H. Fischer, and E.A. Clark. 1996. CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation. J. Exp. Med. 183: 547-560.
50. Katz, H.R., and K.F. Austen. 1997. A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family. J. Immunol. 158: 5065-5070.
51. Kubagawa, H., P.D. Burrows, and M.D. Cooper. 1997. A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc. Natl. Acad. Sci. USA. 94:5261-5266.
52. Kharitonenkov, A., Z. Chen, I. Sures, H. Wang, J. Schilling, and A. Ullrich. 1997. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature (Lond.). 386: 181-186.
53. Nakamura, M.C., E.C. Niemi, M.J. Fisher, L.D. Shultz, W.E. Seaman, and J.C. Ryan. 1997. Mouse Ly-49A interrupts early signaling events in natural killer cell cytotoxicity with the SHP-1 tyrosine phosphatase. J. Exp. Med. 185:673-684.
54. Houchins, J.P., L.L. Lanier, E.C. Niemi, J.H. Phillips, and J.C. Ryan. 1997. Natural killer cell cytolytic activity is inhibited by NKG2-A and activated by NKG2-C. J. Immunol. 158:3603-3609.
55. Guthmann, M.D., M. Tal, and I. Pecht. 1995. A secretion inhibitory signal transduction molecule on mast cells is another C-type lectin. Proc. Natl. Acad. Sci. USA. 92:9397-9401.
56. Wershil, B.K., G.T. Furuta, J.A. Lavigne, A.R. Choudhury, Z.S. Wang, and S.J. Galli. 1995. Dexamethasone or cyclosporin A suppress mast cell-leukocyte cytokine cascades. Multiple mechanisms of inhibition of IgE-and mast cell-dependent cutaneous inflammation in the mouse. J. Immunol. 154:1391-1398.
57. Weber, S., M. Babina, G. Feller, and B.M. Henz. 1997. Human leukaemic (HMC-1) and normal skin mast cells express beta 2-integrins: characterization of beta 2-integrins and ICAM-1 on HMC-1 cells. Scand. J. Immunol. 45:471-481.