메뉴 건너뛰기




Volumn 11, Issue 3, 2004, Pages 459-476

Targeting the androgen receptor: Improving outcomes for castration-resistant prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

17 ALLYLAMINO 17 DEMETHOXYGELDANAMYCIN; ANDROGEN RECEPTOR; ANDROSTANOLONE; ANDROSTENEDIOL; ANTIANDROGEN; BICALUTAMIDE; DIETHYLSTILBESTROL; ESTRADIOL; ESTROGEN; FLUTAMIDE; GELDANAMYCIN; GONADORELIN AGONIST; GONADORELIN ANTAGONIST; HYDROXYFLUTAMIDE; LEUPRORELIN; MEGESTROL ACETATE; NILUTAMIDE; PROSTATE SPECIFIC ANTIGEN; PROTEIN ARA54; PROTEIN ARA55; PROTEIN ARA70; REGULATOR PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 4944246790     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.00525     Document Type: Review
Times cited : (209)

References (118)
  • 2
    • 0031749852 scopus 로고    scopus 로고
    • Incidence and characteristics of antiandrogen withdrawal syndrome in prostate cancer after treatment with chlormadinone acetate
    • Akakura K, Akimoto S, Furuya Y & Ito H 1998 Incidence and characteristics of antiandrogen withdrawal syndrome in prostate cancer after treatment with chlormadinone acetate. European Urology 33 567-571.
    • (1998) European Urology , vol.33 , pp. 567-571
    • Akakura, K.1    Akimoto, S.2    Furuya, Y.3    Ito, H.4
  • 7
    • 2542638568 scopus 로고    scopus 로고
    • Differential modulation of androgen receptor transcriptional activity by the nuclear receptor corepressor (N-CoR)
    • Berrevoets CA, Umar A, Trapman J & Brinkmann AO 2004 Differential modulation of androgen receptor transcriptional activity by the nuclear receptor corepressor (N-CoR). Biochemical Journal 379 1147-1154.
    • (2004) Biochemical Journal , vol.379 , pp. 1147-1154
    • Berrevoets, C.A.1    Umar, A.2    Trapman, J.3    Brinkmann, A.O.4
  • 8
    • 0029027627 scopus 로고
    • Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbestrol
    • Bissada NK & Kaczmarek AT 1995 Complete remission of hormone refractory adenocarcinoma of the prostate in response to withdrawal of diethylstilbestrol. Journal of Urology 153 1944-1945.
    • (1995) Journal of Urology , vol.153 , pp. 1944-1945
    • Bissada, N.K.1    Kaczmarek, A.T.2
  • 12
    • 0035740251 scopus 로고    scopus 로고
    • Contribution of the androgen receptor to prostate cancer predisposition and progression
    • Buchanan G, Irvine RA, Coetzee GA & Tilley WD 2001a Contribution of the androgen receptor to prostate cancer predisposition and progression. Cancer Metastasis Reviews 20 207-223.
    • (2001) Cancer Metastasis Reviews , vol.20 , pp. 207-223
    • Buchanan, G.1    Irvine, R.A.2    Coetzee, G.A.3    Tilley, W.D.4
  • 18
    • 85047683640 scopus 로고    scopus 로고
    • Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor
    • Cheng S, Brzostek S, Lee SR, Hollenberg AN & Balk SP 2002 Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Molecular Endocrinology 16 1492-1501.
    • (2002) Molecular Endocrinology , vol.16 , pp. 1492-1501
    • Cheng, S.1    Brzostek, S.2    Lee, S.R.3    Hollenberg, A.N.4    Balk, S.P.5
  • 19
    • 0037211467 scopus 로고    scopus 로고
    • Squalene epoxidase as hypocholesterolemic drug target revisited
    • Chugh A, Ray A & Gupta JB 2003 Squalene epoxidase as hypocholesterolemic drug target revisited. Progress in Lipid Research 42 37-50.
    • (2003) Progress in Lipid Research , vol.42 , pp. 37-50
    • Chugh, A.1    Ray, A.2    Gupta, J.B.3
  • 20
    • 0033022342 scopus 로고    scopus 로고
    • A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase
    • Craft N, Shostak Y, Carey M & Sawyers CL 1999 A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase. Nature Medicine 5 280-285.
    • (1999) Nature Medicine , vol.5 , pp. 280-285
    • Craft, N.1    Shostak, Y.2    Carey, M.3    Sawyers, C.L.4
  • 21
    • 0028113415 scopus 로고
    • Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor
    • Culig Z, Hobisch A, Cronauer MV, Radmayr C, Trapman J, Hittmair A, Bartsch G & Klocker H 1994 Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor. Cancer Research 54 5474-5478.
    • (1994) Cancer Research , vol.54 , pp. 5474-5478
    • Culig, Z.1    Hobisch, A.2    Cronauer, M.V.3    Radmayr, C.4    Trapman, J.5    Hittmair, A.6    Bartsch, G.7    Klocker, H.8
  • 23
    • 0029007052 scopus 로고
    • Dramatic prostate specific antigen decrease in response to discontinuation of megestrol acetate in advanced prostate cancer: Expansion of the antiandrogen withdrawal syndrome
    • Dawson NA & McLeod DG 1995 Dramatic prostate specific antigen decrease in response to discontinuation of megestrol acetate in advanced prostate cancer: expansion of the antiandrogen withdrawal syndrome. Journal of Urology 153 1946-1947.
    • (1995) Journal of Urology , vol.153 , pp. 1946-1947
    • Dawson, N.A.1    McLeod, D.G.2
  • 27
    • 85047697645 scopus 로고    scopus 로고
    • Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor
    • Eder IE, Hoffmann J, Rogatsch H, Schafer G, Zopf D, Bartsch G & Klocker H 2002 Inhibition of LNCaP prostate tumor growth in vivo by an antisense oligonucleotide directed against the human androgen receptor. Cancer Gene Therapy 9 117-125.
    • (2002) Cancer Gene Therapy , vol.9 , pp. 117-125
    • Eder, I.E.1    Hoffmann, J.2    Rogatsch, H.3    Schafer, G.4    Zopf, D.5    Bartsch, G.6    Klocker, H.7
  • 30
    • 0019478982 scopus 로고
    • The response of metastatic adenocarcinoma of the prostate to exogenous testosterone
    • Fowler JE Jr & Whitmore WF Jr 1981 The response of metastatic adenocarcinoma of the prostate to exogenous testosterone. Journal of Urology 126 372-375.
    • (1981) Journal of Urology , vol.126 , pp. 372-375
    • Fowler Jr., J.E.1    Whitmore Jr., W.F.2
  • 31
    • 0021220507 scopus 로고
    • Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen therapy
    • Geller J, Albert JD, Nachtsheim DA & Loza D 1984a Comparison of prostatic cancer tissue dihydrotestosterone levels at the time of relapse following orchiectomy or estrogen therapy. Journal of Urology 132 693-696.
    • (1984) Journal of Urology , vol.132 , pp. 693-696
    • Geller, J.1    Albert, J.D.2    Nachtsheim, D.A.3    Loza, D.4
  • 33
    • 0036645414 scopus 로고    scopus 로고
    • Molecular biology of the androgen receptor
    • Gelmann EP 2002 Molecular biology of the androgen receptor. Journal of Clinical Oncology 20 3001-3015.
    • (2002) Journal of Clinical Oncology , vol.20 , pp. 3001-3015
    • Gelmann, E.P.1
  • 37
    • 0033672431 scopus 로고    scopus 로고
    • Modifying histones to tame cancer: Clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors
    • Gore SD & Carducci MA 2000 Modifying histones to tame cancer: clinical development of sodium phenylbutyrate and other histone deacetylase inhibitors. Expert Opinion on Investigational Drugs 9 2923-2934.
    • (2000) Expert Opinion on Investigational Drugs , vol.9 , pp. 2923-2934
    • Gore, S.D.1    Carducci, M.A.2
  • 40
    • 0032535307 scopus 로고    scopus 로고
    • Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes
    • Gregory CW, Hamil KG, Kim D, Hall SH, Pretlow TG, Mohler JL & French FS 1998 Androgen receptor expression in androgen-independent prostate cancer is associated with increased expression of androgen-regulated genes. Cancer Research 58 5718-5724.
    • (1998) Cancer Research , vol.58 , pp. 5718-5724
    • Gregory, C.W.1    Hamil, K.G.2    Kim, D.3    Hall, S.H.4    Pretlow, T.G.5    Mohler, J.L.6    French, F.S.7
  • 41
    • 0035300409 scopus 로고    scopus 로고
    • Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
    • Gregory CW, Johnson RT, Mohler JL, French FS & Wilson EM 2001a Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Research 61 2892-2898.
    • (2001) Cancer Research , vol.61 , pp. 2892-2898
    • Gregory, C.W.1    Johnson, R.T.2    Mohler, J.L.3    French, F.S.4    Wilson, E.M.5
  • 42
  • 46
    • 0035212580 scopus 로고    scopus 로고
    • Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide
    • Haapala K, Hyytinen ER, Roiha M, Laurila M, Rantala I, Helin HJ & Koivisto PA 2001 Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide. Laboratory Investigation 81 1647-1651.
    • (2001) Laboratory Investigation , vol.81 , pp. 1647-1651
    • Haapala, K.1    Hyytinen, E.R.2    Roiha, M.3    Laurila, M.4    Rantala, I.5    Helin, H.J.6    Koivisto, P.A.7
  • 47
    • 0035815749 scopus 로고    scopus 로고
    • Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer
    • Han G, Foster BA, Mistry S, Buchanan G, Harris JM, Tilley WD & Greenberg NM 2001 Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer. Journal of Biological Chemistry 276 11204-11213.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 11204-11213
    • Han, G.1    Foster, B.A.2    Mistry, S.3    Buchanan, G.4    Harris, J.M.5    Tilley, W.D.6    Greenberg, N.M.7
  • 52
    • 84928580276 scopus 로고
    • Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C & Hodges CV 1941 Studies on prostatic cancer: I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. Cancer Research 1 293-297.
    • (1941) Cancer Research , vol.1 , pp. 293-297
    • Huggins, C.1    Hodges, C.V.2
  • 53
    • 0001189211 scopus 로고
    • Studies on prostatic cancer. II. The effect of castration on advanced carcinoma of the prostate gland
    • Huggins C, Stevens RE & Hodges CV 1941 Studies on prostatic cancer. II. The effect of castration on advanced carcinoma of the prostate gland. Archives of Surgery 43 209-228.
    • (1941) Archives of Surgery , vol.43 , pp. 209-228
    • Huggins, C.1    Stevens, R.E.2    Hodges, C.V.3
  • 57
    • 0037404165 scopus 로고    scopus 로고
    • Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails
    • Kassouf W, Tanguay S & Aprikian AG 2003 Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails. Journal of Urology 169 1742-1744.
    • (2003) Journal of Urology , vol.169 , pp. 1742-1744
    • Kassouf, W.1    Tanguay, S.2    Aprikian, A.G.3
  • 58
    • 0031739928 scopus 로고    scopus 로고
    • Endocrine withdrawal syndrome and its relevance to the management of hormone refractory prostate cancer
    • Kelly WK 1998 Endocrine withdrawal syndrome and its relevance to the management of hormone refractory prostate cancer. European Urology 34 18-23.
    • (1998) European Urology , vol.34 , pp. 18-23
    • Kelly, W.K.1
  • 59
    • 0027477695 scopus 로고
    • Prostate specific antigen decline after antiandrogen withdrawal: The flutamide withdrawal syndrome
    • Kelly WK & Scher HI 1993 Prostate specific antigen decline after antiandrogen withdrawal: the flutamide withdrawal syndrome. Journal of Urology 149 607-609.
    • (1993) Journal of Urology , vol.149 , pp. 607-609
    • Kelly, W.K.1    Scher, H.I.2
  • 60
    • 0030929675 scopus 로고    scopus 로고
    • Steroid hormone withdrawal syndromes. Pathophysiology and clinical significance
    • Kelly WK, Slovin S & Scher HI 1997 Steroid hormone withdrawal syndromes. Pathophysiology and clinical significance. Urologic Clinics of North America 24 421-431.
    • (1997) Urologic Clinics of North America , vol.24 , pp. 421-431
    • Kelly, W.K.1    Slovin, S.2    Scher, H.I.3
  • 62
    • 0036141411 scopus 로고    scopus 로고
    • Androgen receptor expression and cellular proliferation during transition from androgen-dependent to recurrent growth after castration in the CWR22 prostate cancer xenograft
    • Kim D, Gregory CW, French FS, Smith GJ & Mohler JL 2002 Androgen receptor expression and cellular proliferation during transition from androgen-dependent to recurrent growth after castration in the CWR22 prostate cancer xenograft. American Journal of Pathology 160 219-226.
    • (2002) American Journal of Pathology , vol.160 , pp. 219-226
    • Kim, D.1    Gregory, C.W.2    French, F.S.3    Smith, G.J.4    Mohler, J.L.5
  • 63
    • 0032850869 scopus 로고    scopus 로고
    • Androgen receptor gene amplification increases tissue PSA protein expression in hormone-refractory prostate carcinoma
    • Koivisto PA & Helin HJ 1999 Androgen receptor gene amplification increases tissue PSA protein expression in hormone-refractory prostate carcinoma. Journal of Pathology 189 219-223.
    • (1999) Journal of Pathology , vol.189 , pp. 219-223
    • Koivisto, P.A.1    Helin, H.J.2
  • 66
    • 0345868307 scopus 로고    scopus 로고
    • Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy
    • Kojima S, Suzuki H, Akakura K, Shimbo M, Ichikawa T & Ito H 2004 Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy. Journal of Urology 171 679-683.
    • (2004) Journal of Urology , vol.171 , pp. 679-683
    • Kojima, S.1    Suzuki, H.2    Akakura, K.3    Shimbo, M.4    Ichikawa, T.5    Ito, H.6
  • 69
    • 0036682002 scopus 로고    scopus 로고
    • Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease
    • LaTulippe E, Satagopan J, Smith A, Scher H, Scardino P, Reuter V & Gerald WL 2002 Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Research 62 4499-4506.
    • (2002) Cancer Research , vol.62 , pp. 4499-4506
    • LaTulippe, E.1    Satagopan, J.2    Smith, A.3    Scher, H.4    Scardino, P.5    Reuter, V.6    Gerald, W.L.7
  • 70
    • 1842668004 scopus 로고    scopus 로고
    • Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells
    • Lee SO, Lou W, Hou M, De Miguel F, Gerber L & Gao AC 2003 Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells. Clinical Cancer Research 9 370-376.
    • (2003) Clinical Cancer Research , vol.9 , pp. 370-376
    • Lee, S.O.1    Lou, W.2    Hou, M.3    De Miguel, F.4    Gerber, L.5    Gao, A.C.6
  • 71
    • 0037216526 scopus 로고    scopus 로고
    • AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR
    • Li P, Lee H, Guo S, Unterman TG, Jenster G & Bai W 2003 AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. Molecular and Cellular Biology 23 104-118.
    • (2003) Molecular and Cellular Biology , vol.23 , pp. 104-118
    • Li, P.1    Lee, H.2    Guo, S.3    Unterman, T.G.4    Jenster, G.5    Bai, W.6
  • 74
    • 1542327277 scopus 로고    scopus 로고
    • Inhibitors of JAKs/STATs and the kinases: A possible new cluster of drugs
    • Luo C & Laaja P 2004 Inhibitors of JAKs/STATs and the kinases: a possible new cluster of drugs. Drug Discovery Today 9 268-275.
    • (2004) Drug Discovery Today , vol.9 , pp. 268-275
    • Luo, C.1    Laaja, P.2
  • 80
    • 0029814415 scopus 로고    scopus 로고
    • Activation of the human androgen receptor through a protein kinase A signaling pathway
    • Nazareth LV & Weigel NL 1996 Activation of the human androgen receptor through a protein kinase A signaling pathway. Journal of Biological Chemistry 271 19900-19907.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 19900-19907
    • Nazareth, L.V.1    Weigel, N.L.2
  • 82
    • 0028898510 scopus 로고
    • Withdrawal phenomenon with the antiandrogen casodex
    • Nieh PT 1995 Withdrawal phenomenon with the antiandrogen casodex. Journal of Urology 153 1070-1072.
    • (1995) Journal of Urology , vol.153 , pp. 1070-1072
    • Nieh, P.T.1
  • 83
    • 0027482359 scopus 로고
    • Dominant negative regulation of trans-activation by the rat androgen receptor: Roles of the N-terminal domain and heterodimer formation
    • Palvimo JJ, Kallio PJ, Ikonen T, Mehto M & Janne OA 1993 Dominant negative regulation of trans-activation by the rat androgen receptor: roles of the N-terminal domain and heterodimer formation. Molecular Endocrinology 7 1399-1407.
    • (1993) Molecular Endocrinology , vol.7 , pp. 1399-1407
    • Palvimo, J.J.1    Kallio, P.J.2    Ikonen, T.3    Mehto, M.4    Janne, O.A.5
  • 86
    • 0031932638 scopus 로고    scopus 로고
    • Image analysis of androgen receptor immunostaining in prostate cancer accurately predicts response to hormonal therapy
    • Prins GS, Sklarew RJ & Pertschuk LP 1998 Image analysis of androgen receptor immunostaining in prostate cancer accurately predicts response to hormonal therapy. Journal of Urology 159 641-649.
    • (1998) Journal of Urology , vol.159 , pp. 641-649
    • Prins, G.S.1    Sklarew, R.J.2    Pertschuk, L.P.3
  • 87
    • 0031444238 scopus 로고    scopus 로고
    • Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone
    • Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW & Pearl LH 1997 Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone. Cell 90 65-75.
    • (1997) Cell , vol.90 , pp. 65-75
    • Prodromou, C.1    Roe, S.M.2    O'Brien, R.3    Ladbury, J.E.4    Piper, P.W.5    Pearl, L.H.6
  • 88
    • 0034635553 scopus 로고    scopus 로고
    • Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway
    • Rowan BG, Weigel NL & O'Malley BW 2000 Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway. Journal of Biological Chemistry 275 4475-4483.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 4475-4483
    • Rowan, B.G.1    Weigel, N.L.2    O'Malley, B.W.3
  • 89
    • 0027536495 scopus 로고
    • Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Heterogeneity as a predictor of response to hormonal therapy
    • Sadi MV & Barrack ER 1993 Image analysis of androgen receptor immunostaining in metastatic prostate cancer. Heterogeneity as a predictor of response to hormonal therapy. Cancer 71 2574-2580.
    • (1993) Cancer , vol.71 , pp. 2574-2580
    • Sadi, M.V.1    Barrack, E.R.2
  • 90
    • 0037303769 scopus 로고    scopus 로고
    • Prostate carcinoma: Defining therapeutic objectives and improving overall outcomes
    • Scher HI 2003 Prostate carcinoma: defining therapeutic objectives and improving overall outcomes. Cancer 97 758-771.
    • (2003) Cancer , vol.97 , pp. 758-771
    • Scher, H.I.1
  • 91
    • 0027203411 scopus 로고
    • Flutamide withdrawal syndrome: Its impact on clinical trials in hormone-refractory prostate cancer
    • Scher HI & Kelly WK 1993 Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancer. Journal of Clinical Oncology 11 1566-1572.
    • (1993) Journal of Clinical Oncology , vol.11 , pp. 1566-1572
    • Scher, H.I.1    Kelly, W.K.2
  • 92
    • 0031048446 scopus 로고    scopus 로고
    • The antiandrogen withdrawal syndrome in relapsed prostate cancer
    • Scher HI & Kolvenbag GJ 1997 The antiandrogen withdrawal syndrome in relapsed prostate cancer. European Urology 31 3-7.
    • (1997) European Urology , vol.31 , pp. 3-7
    • Scher, H.I.1    Kolvenbag, G.J.2
  • 93
    • 0028805834 scopus 로고
    • Hormone-refractory (D3) prostate cancer: Refining the concept
    • Scher HI, Steineck G & Kelly WK 1995 Hormone-refractory (D3) prostate cancer: refining the concept. Urology 46 142-148.
    • (1995) Urology , vol.46 , pp. 142-148
    • Scher, H.I.1    Steineck, G.2    Kelly, W.K.3
  • 94
    • 0031205141 scopus 로고    scopus 로고
    • Re: Characterization of patients with androgen independent prostatic carcinoma whose serum prostate specific antigen decreased following flutamide withdrawal
    • Small EJ 1997 Re: Characterization of patients with androgen independent prostatic carcinoma whose serum prostate specific antigen decreased following flutamide withdrawal [letter; comment]. Journal of Urology 158 552.
    • (1997) Journal of Urology , vol.158 , pp. 552
    • Small, E.J.1
  • 95
    • 0028256111 scopus 로고
    • Prostate-specific antigen decline after casodex withdrawal: Evidence for an antiandrogen withdrawal syndrome
    • Small EJ & Carroll PR 1994 Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome. Urology 43 408-410.
    • (1994) Urology , vol.43 , pp. 408-410
    • Small, E.J.1    Carroll, P.R.2
  • 96
    • 0029084601 scopus 로고
    • The antiandrogen withdrawal syndrome. Experience in a large cohort of unselected patients with advanced prostate cancer
    • Small EJ & Srinivas S 1995 The antiandrogen withdrawal syndrome. Experience in a large cohort of unselected patients with advanced prostate cancer. Cancer 76 1428-1434.
    • (1995) Cancer , vol.76 , pp. 1428-1434
    • Small, E.J.1    Srinivas, S.2
  • 98
    • 0142125911 scopus 로고    scopus 로고
    • Hsp90 as a therapeutic target in prostate cancer
    • Solit DB, Scher HI & Rosen N 2003 Hsp90 as a therapeutic target in prostate cancer. Seminars in Oncology 30 709-716.
    • (2003) Seminars in Oncology , vol.30 , pp. 709-716
    • Solit, D.B.1    Scher, H.I.2    Rosen, N.3
  • 99
    • 0031005361 scopus 로고    scopus 로고
    • Crystal structure of an Hsp90-geldanamycin complex: Targeting of a protein chaperone by an antitumor agent
    • Stebbins CE, Russo AA, Schneider C, Rosen N, Hartl FU & Pavletich NP 1997 Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent. Cell 89 239-250.
    • (1997) Cell , vol.89 , pp. 239-250
    • Stebbins, C.E.1    Russo, A.A.2    Schneider, C.3    Rosen, N.4    Hartl, F.U.5    Pavletich, N.P.6
  • 101
    • 0030063211 scopus 로고    scopus 로고
    • Androgen receptor content of prostate carcinoma cells estimated by immunohistochemistry is related to prognosis of patients with stage D2 prostate carcinoma
    • Takeda H, Akakura K, Masai M, Akimoto S, Yatani R & Shimazaki J 1996 Androgen receptor content of prostate carcinoma cells estimated by immunohistochemistry is related to prognosis of patients with stage D2 prostate carcinoma. Cancer 77 934-940.
    • (1996) Cancer , vol.77 , pp. 934-940
    • Takeda, H.1    Akakura, K.2    Masai, M.3    Akimoto, S.4    Yatani, R.5    Shimazaki, J.6
  • 106
    • 1842318283 scopus 로고
    • Characterisation and expression of a cDNA encoding the human androgen receptor
    • Tilley WD, Marcelli M, Wilson JD & McPhaul 1989 Characterisation and expression of a cDNA encoding the human androgen receptor. PNAS 86 327-331.
    • (1989) PNAS , vol.86 , pp. 327-331
    • Tilley, W.D.1    Marcelli, M.2    Wilson, J.D.3    McPhaul4
  • 107
    • 0028111565 scopus 로고
    • Detection of discrete androgen receptor epitopes in prostate cancer by immunostaining: Measurement by color video image analysis
    • Tilley WD, Lim-Tio SS, Horsfall DJ, Aspinall JO, Marshall VR & Skinner JM 1994 Detection of discrete androgen receptor epitopes in prostate cancer by immunostaining: measurement by color video image analysis. Cancer Research 54 096-4102.
    • (1994) Cancer Research , vol.54 , pp. 096-4102
    • Tilley, W.D.1    Lim-Tio, S.S.2    Horsfall, D.J.3    Aspinall, J.O.4    Marshall, V.R.5    Skinner, J.M.6
  • 108
    • 0029915052 scopus 로고    scopus 로고
    • Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence
    • Tilley WD, Buchanan G, Hickey TE & Bentel JM 1996 Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence. Clinical Cancer Research 2 277-285.
    • (1996) Clinical Cancer Research , vol.2 , pp. 277-285
    • Tilley, W.D.1    Buchanan, G.2    Hickey, T.E.3    Bentel, J.M.4
  • 109
    • 3943079773 scopus 로고    scopus 로고
    • Androgen receptor signaling in prostate cancer
    • Eds BE Henderson, BA Ponder & RK Ross. New York: Oxford University Press
    • Tilley WD, Buchanan G & Coetzee GA 2003 Androgen receptor signaling in prostate cancer. In Hormones Genes and Cancer, pp 288-315. Eds BE Henderson, BA Ponder & RK Ross. New York: Oxford University Press.
    • (2003) Hormones Genes and Cancer , pp. 288-315
    • Tilley, W.D.1    Buchanan, G.2    Coetzee, G.A.3
  • 110
    • 0036510548 scopus 로고    scopus 로고
    • Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways
    • Ueda T, Bruchovsky N & Sadar MD 2002a Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways. Journal of Biological Chemistry 277 7076-7085.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 7076-7085
    • Ueda, T.1    Bruchovsky, N.2    Sadar, M.D.3
  • 111
    • 0037064106 scopus 로고    scopus 로고
    • Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells
    • Ueda T, Mawji NR, Bruchovsky N & Sadar MD 2002b Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells. Journal of Biological Chemistry 277 38087-38094.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 38087-38094
    • Ueda, T.1    Mawji, N.R.2    Bruchovsky, N.3    Sadar, M.D.4
  • 113
    • 0034671668 scopus 로고    scopus 로고
    • HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway
    • Wen Y, Hu MC, Makino K, Spohn B, Bartholomeusz G, Yan DH & Hung MC 2000 HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway. Cancer Research 60 6841-6845.
    • (2000) Cancer Research , vol.60 , pp. 6841-6845
    • Wen, Y.1    Hu, M.C.2    Makino, K.3    Spohn, B.4    Bartholomeusz, G.5    Yan, D.H.6    Hung, M.C.7
  • 115
    • 0032510686 scopus 로고    scopus 로고
    • From estrogen to androgen receptor: A new pathway for sex hormones in prostate
    • Yeh S, Miyamoto H, Shima H & Chang C 1998 From estrogen to androgen receptor: a new pathway for sex hormones in prostate. PNAS 95 5527-5532.
    • (1998) PNAS , vol.95 , pp. 5527-5532
    • Yeh, S.1    Miyamoto, H.2    Shima, H.3    Chang, C.4
  • 117
    • 0033545848 scopus 로고    scopus 로고
    • From HER2/Neu signal cascade to androgen receptor and its coactivators: A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells
    • Yeh S, Lin HK, Kang HY, Thin TH, Lin MF & Chang C 1999b From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells. PNAS 96 5458-5463.
    • (1999) PNAS , vol.96 , pp. 5458-5463
    • Yeh, S.1    Lin, H.K.2    Kang, H.Y.3    Thin, T.H.4    Lin, M.F.5    Chang, C.6
  • 118
    • 0036170838 scopus 로고    scopus 로고
    • Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
    • Zegarra-Moro OL, Schmidt LJ, Huang H & Tindall DJ 2002 Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Research 62 1008-1013.
    • (2002) Cancer Research , vol.62 , pp. 1008-1013
    • Zegarra-Moro, O.L.1    Schmidt, L.J.2    Huang, H.3    Tindall, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.