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Volumn 5, Issue , 2008, Pages

Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; LIVE VACCINE; SIMIAN IMMUNODEFICIENCY VIRUS VACCINE; TRANSACTIVATOR PROTEIN;

EID: 48949118745     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-5-44     Document Type: Article
Times cited : (24)

References (44)
  • 2
    • 0032146171 scopus 로고    scopus 로고
    • Protective immunity induced by live attenuated simian immunodeficiency virus
    • 10.1016/S0952-7915(98)80118-0 9722920
    • Johnson RP Desrosiers RC Protective immunity induced by live attenuated simian immunodeficiency virus Curr Opin Immunol 1998, 10:436-443. 10.1016/S0952-7915(98)80118-0 9722920
    • (1998) Curr Opin Immunol , vol.10 , pp. 436-443
    • Johnson, R.P.1    Desrosiers, R.C.2
  • 3
    • 0034633776 scopus 로고    scopus 로고
    • Live attenuated HIV vaccines: Proposal for further research and development
    • 10.1089/088922200750005976 11054258
    • Mills J Desrosiers R Rud E Almond N Live attenuated HIV vaccines: proposal for further research and development AIDS Res Hum Retroviruses 2000, 16:1453-1461. 10.1089/088922200750005976 11054258
    • (2000) AIDS Res Hum Retroviruses , vol.16 , pp. 1453-1461
    • Mills, J.1    Desrosiers, R.2    Rud, E.3    Almond, N.4
  • 4
    • 3042819783 scopus 로고    scopus 로고
    • Live attenuated HIV vaccines: Pitfalls and prospects
    • 10.1097/00001432-200402000-00004 15090885
    • Whitney JB Ruprecht RM Live attenuated HIV vaccines: Pitfalls and prospects Curr Opin Infect Dis 2004, 17:17-26. 10.1097/ 00001432-200402000-00004 15090885
    • (2004) Curr Opin Infect Dis , vol.17 , pp. 17-26
    • Whitney, J.B.1    Ruprecht, R.M.2
  • 5
    • 0028944667 scopus 로고
    • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
    • 10.1126/science.7892606 7892606
    • Baba TW Jeong YS Penninck D Bronson R Greene MF Ruprecht RM Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques Science 1995, 267:1820-1825. 10.1126/science.7892606 7892606
    • (1995) Science , vol.267 , pp. 1820-1825
    • Baba, T.W.1    Jeong, Y.S.2    Penninck, D.3    Bronson, R.4    Greene, M.F.5    Ruprecht, R.M.6
  • 7
    • 0037227694 scopus 로고    scopus 로고
    • A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication
    • 140812 12502842 10.1128/JVI.77.2.1245-1256.2003
    • Chakrabarti LA Metzner KJ Ivanovic T Cheng H Louis-Virelizier J Connor RI Cheng-Mayer C A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication J Virol 2003, 77:1245-1256. 140812 12502842 10.1128/ JVI.77.2.1245-1256.2003
    • (2003) J Virol , vol.77 , pp. 1245-1256
    • Chakrabarti, L.A.1    Metzner, K.J.2    Ivanovic, T.3    Cheng, H.4    Louis-Virelizier, J.5    Connor, R.I.6    Cheng-Mayer, C.7
  • 8
    • 0029031494 scopus 로고
    • Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence
    • 189330 7609080
    • Whatmore AM Cook N Hall GA Sharpe S Rud EW Cranage MP Repair and evolution of nef in vivo modulates simian immunodeficiency virus virulence J Virol 1995, 69:5117-5123. 189330 7609080
    • (1995) J Virol , vol.69 , pp. 5117-5123
    • Whatmore, A.M.1    Cook, N.2    Hall, G.A.3    Sharpe, S.4    Rud, E.W.5    Cranage, M.P.6
  • 9
    • 30344441124 scopus 로고    scopus 로고
    • Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source
    • 1346882 16379007 10.1128/JVI.80.2.1047-1052.2006
    • Churchill MJ Rhodes DI Learmont JC Sullivan JS Wesselingh SL Cooke IR Deacon NJ Gorry PR Longitudinal analysis of human immunodeficiency virus type 1 nef/long terminal repeat sequences in a cohort of long-term survivors infected from a single source J Virol 2006, 80:1047-1052. 1346882 16379007 10.1128/JVI.80.2.1047-1052.2006
    • (2006) J Virol , vol.80 , pp. 1047-1052
    • Churchill, M.J.1    Rhodes, D.I.2    Learmont, J.C.3    Sullivan, J.S.4    Wesselingh, S.L.5    Cooke, I.R.6    Deacon, N.J.7    Gorry, P.R.8
  • 10
    • 0032932711 scopus 로고    scopus 로고
    • Genetic instability of live-attenuated HIV-1 vaccine strains
    • 103934 9882315
    • Berkhout B Verhoef K van Wamel JLB Back B Genetic instability of live-attenuated HIV-1 vaccine strains J Virol 1999, 73:1138-1145. 103934 9882315
    • (1999) J Virol , vol.73 , pp. 1138-1145
    • Berkhout, B.1    Verhoef, K.2    van Wamel, J.L.B.3    Back, B.4
  • 11
    • 0035163747 scopus 로고    scopus 로고
    • Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat
    • 113994 11134311 10.1128/JVI.75.2.979-987.2001
    • Verhoef K Marzio G Hillen W Bujard H Berkhout B Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat J Virol 2001, 75:979-987. 113994 11134311 10.1128/ JVI.75.2.979-987.2001
    • (2001) J Virol , vol.75 , pp. 979-987
    • Verhoef, K.1    Marzio, G.2    Hillen, W.3    Bujard, H.4    Berkhout, B.5
  • 12
    • 0035943707 scopus 로고    scopus 로고
    • Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine
    • 10.1074/jbc.M101604200 11397795
    • Smith SM Khoroshev M Marx PA Orenstein J Jeang KT Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine J Biol Chem 2001, 276:32184-32190. 10.1074/jbc.M101604200 11397795
    • (2001) J Biol Chem , vol.276 , pp. 32184-32190
    • Smith, S.M.1    Khoroshev, M.2    Marx, P.A.3    Orenstein, J.4    Jeang, K.T.5
  • 13
    • 0037196601 scopus 로고    scopus 로고
    • Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus
    • 10.1016/S0168-1702(01)00399-9 11885936
    • Berkhout B Marzio G Verhoef K Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus Virus Res 2002, 82:103-108. 10.1016/S0168-1702(01)00399-9 11885936
    • (2002) Virus Res , vol.82 , pp. 103-108
    • Berkhout, B.1    Marzio, G.2    Verhoef, K.3
  • 14
    • 0037992815 scopus 로고    scopus 로고
    • Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine
    • 10.1586/14760584.1.3.293 12901570
    • Das AT Zhou X Vink M Klaver B Berkhout B Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine Expert Rev Vaccines 2002, 1:293-301. 10.1586/14760584.1.3.293 12901570
    • (2002) Expert Rev Vaccines , vol.1 , pp. 293-301
    • Das, A.T.1    Zhou, X.2    Vink, M.3    Klaver, B.4    Berkhout, B.5
  • 15
    • 4043072810 scopus 로고    scopus 로고
    • A conditionally replicating virus as a novel approach toward an HIV vaccine
    • 15289083
    • Das AT Verhoef K Berkhout B A conditionally replicating virus as a novel approach toward an HIV vaccine Methods Enzymol 2004, 388:359-379. 15289083
    • (2004) Methods Enzymol , vol.388 , pp. 359-379
    • Das, A.T.1    Verhoef, K.2    Berkhout, B.3
  • 16
    • 0034581163 scopus 로고    scopus 로고
    • Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
    • 11044999
    • Baron U Bujard H Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances Methods Enzymol 2000, 327:401-421. 11044999.
    • (2000) Methods Enzymol , vol.327 , pp. 401-421
    • Baron, U.1    Bujard, H.2
  • 17
    • 0035932984 scopus 로고    scopus 로고
    • In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
    • 33470 11353837 10.1073/pnas.111031498
    • Marzio G Verhoef K Vink M Berkhout B In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies Proc Natl Acad Sci USA 2001, 98:6342-6347. 33470 11353837 10.1073/pnas.111031498
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6342-6347
    • Marzio, G.1    Verhoef, K.2    Vink, M.3    Berkhout, B.4
  • 18
    • 0036191195 scopus 로고    scopus 로고
    • Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription
    • 135974 11861878 10.1128/JVI.76.6.3084-3088.2002
    • Marzio G Vink M Verhoef K de Ronde A Berkhout B Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription J Virol 2002, 76:3084-3088. 135974 11861878 10.1128/ JVI.76.6.3084-3088.2002
    • (2002) J Virol , vol.76 , pp. 3084-3088
    • Marzio, G.1    Vink, M.2    Verhoef, K.3    de Ronde, A.4    Berkhout, B.5
  • 19
    • 2442475398 scopus 로고    scopus 로고
    • Viral evolution as a tool to improve the tetracycline-regulated gene expression system
    • 10.1074/jbc.M313895200 14761948
    • Das AT Zhou X Vink M Klaver B Verhoef K Marzio G Berkhout B Viral evolution as a tool to improve the tetracycline-regulated gene expression system J Biol Chem 2004, 279:18776-18782. 10.1074/ jbc.M313895200 14761948
    • (2004) J Biol Chem , vol.279 , pp. 18776-18782
    • Das, A.T.1    Zhou, X.2    Vink, M.3    Klaver, B.4    Verhoef, K.5    Marzio, G.6    Berkhout, B.7
  • 20
    • 33745190519 scopus 로고    scopus 로고
    • The genetic stability of a conditional-live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution
    • 10.1074/jbc.M513400200 16627480
    • Zhou X Vink M Klaver B Verhoef K Marzio G Das AT Berkhout B The genetic stability of a conditional-live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution J Biol Chem 2006, 281:17084-17091. 10.1074/jbc.M513400200 16627480
    • (2006) J Biol Chem , vol.281 , pp. 17084-17091
    • Zhou, X.1    Vink, M.2    Klaver, B.3    Verhoef, K.4    Marzio, G.5    Das, A.T.6    Berkhout, B.7
  • 21
    • 33748854037 scopus 로고    scopus 로고
    • Optimization of the Tet-On system for regulated gene expression through viral evolution
    • 10.1038/sj.gt.3302780 16724096
    • Zhou X Vink M Klaver B Berkhout B Das AT Optimization of the Tet-On system for regulated gene expression through viral evolution Gene Ther 2006, 13:1382-1390. 10.1038/sj.gt.3302780 16724096
    • (2006) Gene Ther , vol.13 , pp. 1382-1390
    • Zhou, X.1    Vink, M.2    Klaver, B.3    Berkhout, B.4    Das, A.T.5
  • 22
    • 33751247662 scopus 로고    scopus 로고
    • Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control
    • 1637113 17094796 10.1186/1742-4690-3-82
    • Zhou X Vink M Berkhout B Das AT Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control Retrovirology 2006, 3:82. 1637113 17094796 10.1186/ 1742-4690-3-82
    • (2006) Retrovirology , vol.3 , pp. 82
    • Zhou, X.1    Vink, M.2    Berkhout, B.3    Das, A.T.4
  • 23
    • 4544259896 scopus 로고    scopus 로고
    • Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1
    • 10.1016/j.virol.2004.07.014 15380352
    • Kiselyeva Y Ito Y Lima RG Grivel JC Das AT Berkhout B Margolis LB Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1 Virol 2004, 328:1-6. 10.1016/ j.virol.2004.07.014 15380352
    • (2004) Virol , vol.328 , pp. 1-6
    • Kiselyeva, Y.1    Ito, Y.2    Lima, R.G.3    Grivel, J.C.4    Das, A.T.5    Berkhout, B.6    Margolis, L.B.7
  • 24
    • 14744272158 scopus 로고    scopus 로고
    • Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry
    • 1075741 15731280 10.1128/JVI.79.6.3855-3858.2005
    • Das AT Baldwin CE Vink M Berkhout B Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry J Virol 2005, 79:3855-3858. 1075741 15731280 10.1128/JVI.79.6.3855-3858.2005
    • (2005) J Virol , vol.79 , pp. 3855-3858
    • Das, A.T.1    Baldwin, C.E.2    Vink, M.3    Berkhout, B.4
  • 25
    • 35148900993 scopus 로고    scopus 로고
    • Construction of a doxycycline-dependent simian immunodeficiency virus reveals a non-transcriptional function of Tat in viral replication
    • 2045552 17670816 10.1128/JVI.01354-07
    • Das AT Klaver B Harwig A Vink M Ooms M Centlivre M Berkhout B Construction of a doxycycline-dependent simian immunodeficiency virus reveals a non-transcriptional function of Tat in viral replication J Virol 2007, 81:11159-11169. 2045552 17670816 10.1128/JVI.01354-07
    • (2007) J Virol , vol.81 , pp. 11159-11169
    • Das, A.T.1    Klaver, B.2    Harwig, A.3    Vink, M.4    Ooms, M.5    Centlivre, M.6    Berkhout, B.7
  • 26
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • 10.1006/jmbi.1999.2700 10329189
    • Mathews DH Sabina J Zuker M Turner DH Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure J Mol Biol 1999, 288:911-940. 10.1006/jmbi.1999.2700 10329189
    • (1999) J Mol Biol , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 27
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • 169194 12824337 10.1093/nar/gkg595
    • Zuker M Mfold web server for nucleic acid folding and hybridization prediction Nucleic Acids Res 2003, 31:3406-3415. 169194 12824337 10.1093/ nar/gkg595
    • (2003) Nucleic Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 28
    • 33745157219 scopus 로고    scopus 로고
    • New, extended hairpin form of the TAR-2 RNA domain points to the structural polymorphism at the 5′ end of the HIV-2 leader RNA
    • 1474061 16738137 10.1093/nar/gkl373
    • Pachulska-Wieczorek K Purzycka KJ Adamiak RW New, extended hairpin form of the TAR-2 RNA domain points to the structural polymorphism at the 5′ end of the HIV-2 leader RNA Nucleic Acids Res 2006, 34:2984-2997. 1474061 16738137 10.1093/nar/gkl373
    • (2006) Nucleic Acids Res , vol.34 , pp. 2984-2997
    • Pachulska-Wieczorek, K.1    Purzycka, K.J.2    Adamiak, R.W.3
  • 29
    • 0026093989 scopus 로고
    • Detailed mutational analysis of TAR RNA: Critical spacing between the bulge and loop recognition domains
    • 329115 1956776 10.1093/nar/19.22.6169
    • Berkhout B Jeang KT Detailed mutational analysis of TAR RNA: Critical spacing between the bulge and loop recognition domains Nucleic Acids Res 1991, 19:6169-6176. 329115 1956776 10.1093/nar/19.22.6169
    • (1991) Nucleic Acids Res , vol.19 , pp. 6169-6176
    • Berkhout, B.1    Jeang, K.T.2
  • 30
    • 0035038089 scopus 로고    scopus 로고
    • Two alternating structures for the HIV-1 leader RNA
    • 1370064 11214176 10.1017/S1355838201001881
    • Huthoff H Berkhout B Two alternating structures for the HIV-1 leader RNA RNA 2001, 7:143-157. 1370064 11214176 10.1017/S1355838201001881
    • (2001) RNA , vol.7 , pp. 143-157
    • Huthoff, H.1    Berkhout, B.2
  • 31
    • 0037205458 scopus 로고    scopus 로고
    • In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes
    • 10.1074/jbc.M200950200 11896057
    • Berkhout B Ooms M Beerens N Huthoff H Southern E Verhoef K In vitro evidence that the untranslated leader of the HIV-1 genome is an RNA checkpoint that regulates multiple functions through conformational changes J Biol Chem 2002, 277:19967-19975. 10.1074/jbc.M200950200 11896057
    • (2002) J Biol Chem , vol.277 , pp. 19967-19975
    • Berkhout, B.1    Ooms, M.2    Beerens, N.3    Huthoff, H.4    Southern, E.5    Verhoef, K.6
  • 32
    • 4544337311 scopus 로고    scopus 로고
    • A riboswitch regulates RNA dimerization and packaging in human immunodeficiency virus type 1 virions
    • 516375 15367648 10.1128/JVI.78.19.10814-10819.2004
    • Ooms M Huthoff H Russell R Liang C Berkhout B A riboswitch regulates RNA dimerization and packaging in human immunodeficiency virus type 1 virions J Virol 2004, 78:10814-10819. 516375 15367648 10.1128/ JVI.78.19.10814-10819.2004
    • (2004) J Virol , vol.78 , pp. 10814-10819
    • Ooms, M.1    Huthoff, H.2    Russell, R.3    Liang, C.4    Berkhout, B.5
  • 33
    • 21744452846 scopus 로고    scopus 로고
    • The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation
    • 10.1021/bi0502588
    • Abbink TEM Ooms M Haasnoot PCJ Berkhout B The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation Biochem 2005, 44;9058-9066. 10.1021/bi0502588
    • (2005) Biochem , vol.44 , pp. 9058-9066
    • Abbink, T.E.M.1    Ooms, M.2    Haasnoot, P.C.J.3    Berkhout, B.4
  • 34
    • 34447261637 scopus 로고    scopus 로고
    • The TAR hairpin of human immunodeficiency virus type-1 can be deleted when not required for Tat-mediated activation of transcription
    • 1933349 17494072 10.1128/JVI.00392-07
    • Das AT Harwig A Vrolijk MM Berkhout B The TAR hairpin of human immunodeficiency virus type-1 can be deleted when not required for Tat-mediated activation of transcription J Virol 2007, 81:7742-7748. 1933349 17494072 10.1128/JVI.00392-07
    • (2007) J Virol , vol.81 , pp. 7742-7748
    • Das, A.T.1    Harwig, A.2    Vrolijk, M.M.3    Berkhout, B.4
  • 35
    • 48149098589 scopus 로고    scopus 로고
    • Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA
    • Advance Access published June 27 18586822
    • Vrolijk MM Ooms M Harwig A Das AT Berkhout B Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA Nucleic Acids Res 2008 Advance Access published June 27 18586822
    • (2008) Nucleic Acids Res
    • Vrolijk, M.M.1    Ooms, M.2    Harwig, A.3    Das, A.T.4    Berkhout, B.5
  • 36
    • 0025222481 scopus 로고
    • The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus
    • 2078405
    • Regier DA Desrosiers RC The complete nucleotide sequence of a pathogenic molecular clone of simian immunodeficiency virus AIDS Res Hum Retroviruses 1990, 6:1221-1231. 2078405
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 1221-1231
    • Regier, D.A.1    Desrosiers, R.C.2
  • 37
    • 0033803425 scopus 로고    scopus 로고
    • Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus
    • 102079 10982327 10.1128/JVI.74.19.8854-8860.2000
    • Guan Y Whitney JB Diallo K Wainberg MA Leader sequences downstream of the primer binding site are important for efficient replication of simian immunodeficiency virus J Virol 2000, 74:8854-8860. 102079 10982327 10.1128/JVI.74.19.8854-8860.2000
    • (2000) J Virol , vol.74 , pp. 8854-8860
    • Guan, Y.1    Whitney, J.B.2    Diallo, K.3    Wainberg, M.A.4
  • 38
    • 84883842434 scopus 로고
    • Long-term cultivation of hypodiploid human tumor cells
    • 14114965
    • Auersperg N Long-term cultivation of hypodiploid human tumor cells J Nat Cancer Inst 1964, 32:135-163. 14114965
    • (1964) J Nat Cancer Inst , vol.32 , pp. 135-163
    • Auersperg, N.1
  • 39
    • 0029063578 scopus 로고
    • Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1
    • 189087 7745720
    • Lusso P Cocchi F Balotta C Markham PD Louie A Farci P Pal R Gallo RC Reitz MS Jr. Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1 J Virol 1995, 69:3712-3720. 189087 7745720
    • (1995) J Virol , vol.69 , pp. 3712-3720
    • Lusso, P.1    Cocchi, F.2    Balotta, C.3    Markham, P.D.4    Louie, A.5    Farci, P.6    Pal, R.7    Gallo, R.C.8    Reitz Jr., M.S.9
  • 42
    • 23844524271 scopus 로고    scopus 로고
    • Highly sensitive SIV plasma viral load assay: Practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS
    • 10.1111/j.1600-0684.2005.00128.x 16128925
    • Cline AN Bess JW Piatak M Jr. Lifson JD Highly sensitive SIV plasma viral load assay: Practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS J Med Primatol 2005, 34:303-312. 10.1111/j.1600-0684.2005.00128.x 16128925
    • (2005) J Med Primatol , vol.34 , pp. 303-312
    • Cline, A.N.1    Bess, J.W.2    Piatak Jr., M.3    Lifson, J.D.4
  • 43
    • 0032427481 scopus 로고    scopus 로고
    • Adaptation of the fluorogenic 5′-nuclease chemistry to a PCR-based reverse transcriptase assay
    • Maudru T Peden KW Adaptation of the fluorogenic 5′-nuclease chemistry to a PCR-based reverse transcriptase assay Biotechn 1998, 25:972-975.
    • (1998) Biotechn , vol.25 , pp. 972-975
    • Maudru, T.1    Peden, K.W.2
  • 44
    • 30644466345 scopus 로고    scopus 로고
    • Factor correction as a tool to eliminate between-session variation in replicate experiments: Application to molecular biology and retrovirology
    • 1360091 16398928 10.1186/1742-4690-3-2
    • Ruijter JM Thygesen HH Schoneveld OJ Das AT Berkhout B Lamers WH Factor correction as a tool to eliminate between-session variation in replicate experiments: Application to molecular biology and retrovirology Retrovirology 2006, 3:1-8. 1360091 16398928 10.1186/1742-4690-3-2
    • (2006) Retrovirology , vol.3 , pp. 1-8
    • Ruijter, J.M.1    Thygesen, H.H.2    Schoneveld, O.J.3    Das, A.T.4    Berkhout, B.5    Lamers, W.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.