메뉴 건너뛰기




Volumn 3, Issue , 2006, Pages

Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; TRANSACTIVATOR PROTEIN; VIRUS DNA;

EID: 33751247662     PISSN: 17424690     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-3-82     Document Type: Article
Times cited : (30)

References (38)
  • 1
    • 0029652922 scopus 로고
    • Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells
    • Almond N, Kent K, Cranage M, Rud E, Clarke B, Stott EJ: Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells. Lancet 1995, 345:1342-1344.
    • (1995) Lancet , vol.345 , pp. 1342-1344
    • Almond, N.1    Kent, K.2    Cranage, M.3    Rud, E.4    Clarke, B.5    Stott, E.J.6
  • 2
    • 0345742598 scopus 로고    scopus 로고
    • Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus
    • Blancou P, Chenciner N, Ho Tsong FR, Monceaux V, Cumont MC, Guetard D, Hurtrel B, Wain-Hobson S: Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus. J Virol 2004, 78:1080-1092.
    • (2004) J Virol , vol.78 , pp. 1080-1092
    • Blancou, P.1    Chenciner, N.2    Ho Tsong, F.R.3    Monceaux, V.4    Cumont, M.C.5    Guetard, D.6    Hurtrel, B.7    Wain-Hobson, S.8
  • 4
    • 0029951823 scopus 로고    scopus 로고
    • Vaccine protection by a triple deletion mutant of simian immunodeficiency virus
    • Wyand MS, Manson KH, Garcia-Moll M, Montefiori D, Desrosiers RC: Vaccine protection by a triple deletion mutant of simian immunodeficiency virus. J Virol 1996, 70:3724-3733.
    • (1996) J Virol , vol.70 , pp. 3724-3733
    • Wyand, M.S.1    Manson, K.H.2    Garcia-Moll, M.3    Montefiori, D.4    Desrosiers, R.C.5
  • 6
    • 0028944667 scopus 로고
    • Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques
    • Baba TW, Jeong YS, Pennick D, Bronson R, Greene MF, Ruprecht RM: Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques. Science 1995, 267:1820-1825.
    • (1995) Science , vol.267 , pp. 1820-1825
    • Baba, T.W.1    Jeong, Y.S.2    Pennick, D.3    Bronson, R.4    Greene, M.F.5    Ruprecht, R.M.6
  • 8
    • 0032932711 scopus 로고    scopus 로고
    • Genetic instability of live, attenuated human immunodeficiency virus type 1 vaccine strains
    • Berkhout B, Verhoef K, van Wamel JL, Back NK: Genetic instability of live, attenuated human immunodeficiency virus type 1 vaccine strains. J Virol 1999, 73:1138-1145.
    • (1999) J Virol , vol.73 , pp. 1138-1145
    • Berkhout, B.1    Verhoef, K.2    van Wamel, J.L.3    Back, N.K.4
  • 9
    • 0037227694 scopus 로고    scopus 로고
    • A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication
    • Chakrabarti LA, Metzner KJ, Ivanovic T, Cheng H, Louis-Virelizier J, Connor RI, Cheng-Mayer C: A truncated form of Nef selected during pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replication. J Virol 2003, 77:1245-1256.
    • (2003) J Virol , vol.77 , pp. 1245-1256
    • Chakrabarti, L.A.1    Metzner, K.J.2    Ivanovic, T.3    Cheng, H.4    Louis-Virelizier, J.5    Connor, R.I.6    Cheng-Mayer, C.7
  • 10
    • 0037196601 scopus 로고    scopus 로고
    • Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus
    • Berkhout B, Marzio G, Verhoef K: Control over HIV-1 replication by an antibiotic; a novel vaccination strategy with a drug-dependent virus. Virus Res 2002, 82:103-108.
    • (2002) Virus Res , vol.82 , pp. 103-108
    • Berkhout, B.1    Marzio, G.2    Verhoef, K.3
  • 11
    • 4043072810 scopus 로고    scopus 로고
    • A conditionally replicating virus as a novel approach toward an HIV vaccine
    • Das AT, Verhoef K, Berkhout B: A conditionally replicating virus as a novel approach toward an HIV vaccine. Methods Enzymol 2004, 388:359-379.
    • (2004) Methods Enzymol , vol.388 , pp. 359-379
    • Das, A.T.1    Verhoef, K.2    Berkhout, B.3
  • 12
    • 0035163747 scopus 로고    scopus 로고
    • Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat
    • Verhoef K, Marzio G, Hillen W, Bujard H, Berkhout B: Strict control of human immunodeficiency virus type 1 replication by a genetic switch: Tet for Tat. J Virol 2001, 75:979-987.
    • (2001) J Virol , vol.75 , pp. 979-987
    • Verhoef, K.1    Marzio, G.2    Hillen, W.3    Bujard, H.4    Berkhout, B.5
  • 13
    • 0035943707 scopus 로고    scopus 로고
    • Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine
    • Smith SM, Khoroshev M, Marx PA, Orenstein J, Jeang KT: Constitutively dead, conditionally live HIV-1 genomes. Ex vivo implications for a live virus vaccine. J Biol Chem 2001, 276:32184-32190.
    • (2001) J Biol Chem , vol.276 , pp. 32184-32190
    • Smith, S.M.1    Khoroshev, M.2    Marx, P.A.3    Orenstein, J.4    Jeang, K.T.5
  • 14
    • 0037992815 scopus 로고    scopus 로고
    • Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine
    • Das AT, Zhou X, Vink M, Klaver B, Berkhout B: Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine. Expert Rev Vaccines 2002, 1:293-301.
    • (2002) Expert Rev Vaccines , vol.1 , pp. 293-301
    • Das, A.T.1    Zhou, X.2    Vink, M.3    Klaver, B.4    Berkhout, B.5
  • 15
    • 0034581163 scopus 로고    scopus 로고
    • Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
    • Baron U, Bujard H: Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances. Methods Enzymol 2000, 327:401-421.
    • (2000) Methods Enzymol , vol.327 , pp. 401-421
    • Baron, U.1    Bujard, H.2
  • 17
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
    • Urlinger S, Baron U, Thellmann M, Hasan MT, Bujard H, Hillen W: Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 2000, 97:7963-7968.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3    Hasan, M.T.4    Bujard, H.5    Hillen, W.6
  • 18
    • 4544259896 scopus 로고    scopus 로고
    • Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1
    • Kiselyeva Y, Ito Y, Lima RG, Grivel JC, Das AT, Berkhout B, Margolis LB: Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1. Virology 2004, 328:1-6.
    • (2004) Virology , vol.328 , pp. 1-6
    • Kiselyeva, Y.1    Ito, Y.2    Lima, R.G.3    Grivel, J.C.4    Das, A.T.5    Berkhout, B.6    Margolis, L.B.7
  • 19
    • 2442475398 scopus 로고    scopus 로고
    • Viral evolution as a tool to improve the tetracycline-regulated gene expression system
    • Das AT, Zhou X, Vink M, Klaver B, Verhoef K, Marzio G, Berkhout B: Viral evolution as a tool to improve the tetracycline-regulated gene expression system. J Biol Chem 2004, 279:18776-18782.
    • (2004) J Biol Chem , vol.279 , pp. 18776-18782
    • Das, A.T.1    Zhou, X.2    Vink, M.3    Klaver, B.4    Verhoef, K.5    Marzio, G.6    Berkhout, B.7
  • 20
    • 0036191195 scopus 로고    scopus 로고
    • Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription
    • Marzio G, Vink M, Verhoef K, de Ronde A, Berkhout B: Efficient human immunodeficiency virus replication requires a fine-tuned level of transcription. J Virol 2002, 76:3084-3088.
    • (2002) J Virol , vol.76 , pp. 3084-3088
    • Marzio, G.1    Vink, M.2    Verhoef, K.3    de Ronde, A.4    Berkhout, B.5
  • 21
    • 0035932984 scopus 로고    scopus 로고
    • In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies
    • Marzio G, Verhoef K, Vink M, Berkhout B: In vitro evolution of a highly replicating, doxycycline-dependent HIV for applications in vaccine studies. Proc Natl Acad Sci USA 2001, 98:6342-6347.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 6342-6347
    • Marzio, G.1    Verhoef, K.2    Vink, M.3    Berkhout, B.4
  • 22
    • 33748854037 scopus 로고    scopus 로고
    • Optimization of the Tet-On system for regulated gene expression through viral evolution
    • Zhou X, Vink M, Klaver B, Berkhout B, Das AT: Optimization of the Tet-On system for regulated gene expression through viral evolution. Gene Ther 2006, 13:1382-1390.
    • (2006) Gene Ther , vol.13 , pp. 1382-1390
    • Zhou, X.1    Vink, M.2    Klaver, B.3    Berkhout, B.4    Das, A.T.5
  • 23
    • 33745190519 scopus 로고    scopus 로고
    • The genetic stability of a conditional-live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution
    • Zhou X, Vink M, Klaver B, Verhoef K, Marzio G, Das AT, Berkhout B: The genetic stability of a conditional-live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution. J Biol Chem 2006, 281:17084-17091.
    • (2006) J Biol Chem , vol.281 , pp. 17084-17091
    • Zhou, X.1    Vink, M.2    Klaver, B.3    Verhoef, K.4    Marzio, G.5    Das, A.T.6    Berkhout, B.7
  • 24
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M, Bujard H: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992, 89:5547-5551.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 25
    • 0030797223 scopus 로고    scopus 로고
    • Tetracycline-controlled transcription in eukaryotes: Novel transactivators with graded transactivation potential
    • Baron U, Gossen M, Bujard H: Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential. Nucleic Acids Res 1997, 25:2723-2729.
    • (1997) Nucleic Acids Res , vol.25 , pp. 2723-2729
    • Baron, U.1    Gossen, M.2    Bujard, H.3
  • 26
    • 0035815637 scopus 로고    scopus 로고
    • HIV-1 RNA editing, hypermutation, and error-prone reverse transcription
    • Berkhout B, Das AT, Beerens N: HIV-1 RNA editing, hypermutation, and error-prone reverse transcription. Science 2001, 292:7.
    • (2001) Science , vol.292 , pp. 7
    • Berkhout, B.1    Das, A.T.2    Beerens, N.3
  • 27
    • 4444298202 scopus 로고    scopus 로고
    • APOBEC3G versus reverse transcriptase in the generation of HIV-1 drug-resistance mutations
    • Berkhout B, de Ronde A: APOBEC3G versus reverse transcriptase in the generation of HIV-1 drug-resistance mutations. AIDS 2004, 18:1861-1863.
    • (2004) AIDS , vol.18 , pp. 1861-1863
    • Berkhout, B.1    de Ronde, A.2
  • 28
    • 0030896362 scopus 로고    scopus 로고
    • Initial appearance of the 18411e variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase
    • Keulen W, Back NK, van Wijk A, Boucher CA, Berkhout B: Initial appearance of the 18411e variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase. J Virol 1997, 71:3346-3350.
    • (1997) J Virol , vol.71 , pp. 3346-3350
    • Keulen, W.1    Back, N.K.2    van Wijk, A.3    Boucher, C.A.4    Berkhout, B.5
  • 29
    • 0029885139 scopus 로고    scopus 로고
    • Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins
    • Keulen W, Boucher C, Berkhout B: Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins. Antiviral Res 1996, 31:45-57.
    • (1996) Antiviral Res , vol.31 , pp. 45-57
    • Keulen, W.1    Boucher, C.2    Berkhout, B.3
  • 30
    • 0034087676 scopus 로고    scopus 로고
    • Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system
    • Orth P, Schnappinger D, Hillen W, Saenger W, Hinrichs W: Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat Struct Biol 2000, 7:215-219.
    • (2000) Nat Struct Biol , vol.7 , pp. 215-219
    • Orth, P.1    Schnappinger, D.2    Hillen, W.3    Saenger, W.4    Hinrichs, W.5
  • 32
    • 17144375314 scopus 로고    scopus 로고
    • Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: Towards a new virotherapy approach
    • Jeeninga RE, Van der Linden B, Jan B, Van den Berg H, Berkhout B: Construction of a minimal HIV-1 variant that selectively replicates in leukemic derived T-cell lines: towards a new virotherapy approach. Cancer Res 2005, 65:3347-3355.
    • (2005) Cancer Res , vol.65 , pp. 3347-3355
    • Jeeninga, R.E.1    Van der Linden, B.2    Jan, B.3    Van den Berg, H.4    Berkhout, B.5
  • 33
    • 33749601616 scopus 로고    scopus 로고
    • Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias
    • Jeeninga RE, Jan B, Van den Berg H, Berkhout B: Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias. Retrovirology 2006, 3:64.
    • (2006) Retrovirology , vol.3 , pp. 64
    • Jeeninga, R.E.1    Jan, B.2    Van den Berg, H.3    Berkhout, B.4
  • 34
    • 7644236011 scopus 로고    scopus 로고
    • Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor
    • Baldwin CE, Sanders RW, Deng Y, Jurriaans S, Lange JM, Lu M, Berkhout B: Emergence of a drug-dependent human immunodeficiency virus type 1 variant during therapy with the T20 fusion inhibitor. J Virol 2004, 78:12428-12437.
    • (2004) J Virol , vol.78 , pp. 12428-12437
    • Baldwin, C.E.1    Sanders, R.W.2    Deng, Y.3    Jurriaans, S.4    Lange, J.M.5    Lu, M.6    Berkhout, B.7
  • 35
    • 14744272158 scopus 로고    scopus 로고
    • Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry
    • Das AT, Baldwin CE, Vink M, Berkhout B: Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry. J Virol 2005, 79:3855-3858.
    • (2005) J Virol , vol.79 , pp. 3855-3858
    • Das, A.T.1    Baldwin, C.E.2    Vink, M.3    Berkhout, B.4
  • 36
    • 0026318224 scopus 로고
    • Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-ILAI, HIV-IMAL, and HIV-IELI
    • Peden K, Emerman M, Montagnier L: Changes in growth properties on passage in tissue culture of viruses derived from infectious molecular clones of HIV-ILAI, HIV-IMAL, and HIV-IELI. Virology 1991, 185:661-672.
    • (1991) Virology , vol.185 , pp. 661-672
    • Peden, K.1    Emerman, M.2    Montagnier, L.3
  • 37
    • 84883842434 scopus 로고
    • Long-term cultivation of hypodiploid human tumor cells
    • Auersperg N: Long-term cultivation of hypodiploid human tumor cells. J Natl Cancer Inst 1964, 32:135-163.
    • (1964) J Natl Cancer Inst , vol.32 , pp. 135-163
    • Auersperg, N.1
  • 38
    • 30644466345 scopus 로고    scopus 로고
    • Factor correction as a tool to eliminate between-session variation in replicate experiments: Application to molecular biology and retrovirology
    • Ruijter JM, Thygesen HH, Schoneveld OJ, Das AT, Berkhout B, Lamers WH: Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology. Retrovirology 2006, 3:2.
    • (2006) Retrovirology , vol.3 , pp. 2
    • Ruijter, J.M.1    Thygesen, H.H.2    Schoneveld, O.J.3    Das, A.T.4    Berkhout, B.5    Lamers, W.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.