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Volumn 28, Issue SUPP. 3, 2008, Pages

Transforming growth factor β1 induces epithelial-mesenchymal transition by activating the JNK-SMAD3 pathway in rat peritoneal mesothelial cells

Author keywords

c Jun N terminal kinase; EMT; Epithelial mesenchymal transition; JNK; Peritoneal fibrosis; Peritoneal mesothelial cells; Signal transduction; Smad; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COLLAGEN TYPE 1; MESSENGER RNA; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN;

EID: 48749112189     PISSN: 08968608     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (65)

References (34)
  • 1
    • 0035651809 scopus 로고    scopus 로고
    • Peritoneal dialysis in the 21st century: An analysis of current problems and future developments
    • Gokal R. Peritoneal dialysis in the 21st century: an analysis of current problems and future developments. J Am Soc Nephrol 2002; 13(Suppl 1):S104-16.
    • (2002) J Am Soc Nephrol , vol.13 , Issue.SUPPL. 1
    • Gokal, R.1
  • 3
    • 0037377675 scopus 로고    scopus 로고
    • Myofibrobtastic conversion of mesothelial cells
    • Yang AH, Chen JY, Lin JK. Myofibrobtastic conversion of mesothelial cells. Kidney Int 2003; 63:1530-9.
    • (2003) Kidney Int , vol.63 , pp. 1530-1539
    • Yang, A.H.1    Chen, J.Y.2    Lin, J.K.3
  • 5
    • 24644487312 scopus 로고    scopus 로고
    • TGF-β and epithelial-to-mesenchymal transitions
    • Zavadil J, Böttinger EP. TGF-β and epithelial-to-mesenchymal transitions. Oncogene 2005; 24:5764-74.
    • (2005) Oncogene , vol.24 , pp. 5764-5774
    • Zavadil, J.1    Böttinger, E.P.2
  • 6
    • 16844377902 scopus 로고    scopus 로고
    • Cytokines and growth factors involved in peritoneal fibrosis of peritoneal dialysis patients
    • Oh KH, Margetts PJ. Cytokines and growth factors involved in peritoneal fibrosis of peritoneal dialysis patients. Int J Artif Organs 2005; 28:129-34.
    • (2005) Int J Artif Organs , vol.28 , pp. 129-134
    • Oh, K.H.1    Margetts, P.J.2
  • 7
    • 0034030142 scopus 로고    scopus 로고
    • TGF-beta signaling by Smad proteins
    • Miyazono K. TGF-beta signaling by Smad proteins. Cytokine Growth Factor Rev 2000; 11:15-22.
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 15-22
    • Miyazono, K.1
  • 8
    • 18244401140 scopus 로고    scopus 로고
    • Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury
    • Tahashi Y, Matsuzaki K, Date M, Yoshida K, Furukawa F, Sugano Y, et al. Differential regulation of TGF-beta signal in hepatic stellate cells between acute and chronic rat liver injury. Hepatology 2002; 35:49-61.
    • (2002) Hepatology , vol.35 , pp. 49-61
    • Tahashi, Y.1    Matsuzaki, K.2    Date, M.3    Yoshida, K.4    Furukawa, F.5    Sugano, Y.6
  • 9
    • 0037498439 scopus 로고    scopus 로고
    • Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
    • Lan HY, Nu W, Tomita N, Huang XR, Li JH, Zhu HJ, et al. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol 2003; 14:1535-48.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1535-1548
    • Lan, H.Y.1    Nu, W.2    Tomita, N.3    Huang, X.R.4    Li, J.H.5    Zhu, H.J.6
  • 10
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-β signaling from cell membrane to the nucleus
    • Shi Y, Massague J. Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 2003; 113:685-700.
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 11
    • 0033104505 scopus 로고    scopus 로고
    • TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase dependent, Smad4-independent pathway
    • Hocevar BA, Brown TL, Howe PH. TGF-β induces fibronectin synthesis through a c-Jun N-terminal kinase dependent, Smad4-independent pathway. EMBOJ 1999; 18:1345-56.
    • (1999) EMBOJ , vol.18 , pp. 1345-1356
    • Hocevar, B.A.1    Brown, T.L.2    Howe, P.H.3
  • 13
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 2000; 103:239-52.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 14
    • 0028229012 scopus 로고
    • The stress-activated protein kinase subfamily of c-Jun kinase
    • Kyriakis JM. The stress-activated protein kinase subfamily of c-Jun kinase. Nature 1994; 369:156-60.
    • (1994) Nature , vol.369 , pp. 156-160
    • Kyriakis, J.M.1
  • 15
    • 0033601179 scopus 로고    scopus 로고
    • interdependent SMAD and JNK signaling in transforming growth factor-beta mediated transcription
    • Engel ME, McDonnell MA, Law BK, Moses HL. interdependent SMAD and JNK signaling in transforming growth factor-beta mediated transcription. J Biol Chem 1999; 274:37413-20.
    • (1999) J Biol Chem , vol.274 , pp. 37413-37420
    • Engel, M.E.1    McDonnell, M.A.2    Law, B.K.3    Moses, H.L.4
  • 16
    • 6044261233 scopus 로고    scopus 로고
    • TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorytation at the Unker regions
    • Mori S, Matsuzaki K, Yoshida K, Furukawa F, Tahashi Y, Yamagata H, et al. TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorytation at the Unker regions. Oncogene 2004; 23:7416-29.
    • (2004) Oncogene , vol.23 , pp. 7416-7429
    • Mori, S.1    Matsuzaki, K.2    Yoshida, K.3    Furukawa, F.4    Tahashi, Y.5    Yamagata, H.6
  • 17
    • 20244376914 scopus 로고    scopus 로고
    • Transforming growth factor-beta and platelet-derived growth factor signatvia c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury
    • Yoshida K, Matsuzaki K, Mori S, Tahashi Y, Yamagata H, Furukawa F, et al. Transforming growth factor-beta and platelet-derived growth factor signatvia c-Jun N-terminal kinase-dependent Smad2/3 phosphorylation in rat hepatic stellate cells after acute liver injury. Am J Pathol 2005; 166:1029-39.
    • (2005) Am J Pathol , vol.166 , pp. 1029-1039
    • Yoshida, K.1    Matsuzaki, K.2    Mori, S.3    Tahashi, Y.4    Yamagata, H.5    Furukawa, F.6
  • 18
    • 33846441237 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: Its potential role in peritoneal cavity local defense
    • Zhang YF, Yang X, Zhang YJ, Sun YL, Zou XL, Kong OY, et al. Peroxisome proliferator-activated receptor-gamma is expressed by rat peritoneal mesothelial cells: its potential role in peritoneal cavity local defense. Am S Nephrol 2006; 26:602-11.
    • (2006) Am S Nephrol , vol.26 , pp. 602-611
    • Zhang, Y.F.1    Yang, X.2    Zhang, Y.J.3    Sun, Y.L.4    Zou, X.L.5    Kong, O.Y.6
  • 19
    • 0036786834 scopus 로고    scopus 로고
    • TGF-β signaling in renal disease
    • Bottinger EP, Bitzer M. TGF-β signaling in renal disease. J Am Soc Nephrol 2002; 13:2600-10.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2600-2610
    • Bottinger, E.P.1    Bitzer, M.2
  • 20
    • 24644476507 scopus 로고    scopus 로고
    • Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: Implications for carcino-genesis
    • Javelaud D, Mauviel A. Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: implications for carcino-genesis. Oncogene 2005; 24:5742-50.
    • (2005) Oncogene , vol.24 , pp. 5742-5750
    • Javelaud, D.1    Mauviel, A.2
  • 21
    • 0031059867 scopus 로고    scopus 로고
    • Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor beta in the negative growth control of breast cancer cells
    • Frey RS, Mulder KM. Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor beta in the negative growth control of breast cancer cells. Cancer Res 1997; 57:628-33.
    • (1997) Cancer Res , vol.57 , pp. 628-633
    • Frey, R.S.1    Mulder, K.M.2
  • 22
    • 0028061674 scopus 로고
    • Signal transduction by tumor necrosis factor mediated by JNK protein kinases
    • Sluss HK, Barrett T, Derijard B, Davis RJ. Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol 1994; 14:8376-84.
    • (1994) Mol Cell Biol , vol.14 , pp. 8376-8384
    • Sluss, H.K.1    Barrett, T.2    Derijard, B.3    Davis, R.J.4
  • 23
    • 0029885419 scopus 로고    scopus 로고
    • Selective interaction of JNK protein kinase isoforms with transcription factors
    • Gupta S, Barrett T, Whitmarsh AJ, Cavanagh J, Sluss HK, Derijard B, et al. Selective interaction of JNK protein kinase isoforms with transcription factors. EMBOJ 1996; 15:2760-70.
    • (1996) EMBOJ , vol.15 , pp. 2760-2770
    • Gupta, S.1    Barrett, T.2    Whitmarsh, A.J.3    Cavanagh, J.4    Sluss, H.K.5    Derijard, B.6
  • 24
    • 0031035582 scopus 로고    scopus 로고
    • Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling
    • Atfi A, Djelloul S, Chastre E, Davis R, Gespach C. Evidence for a role of Rho-like GTPases and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) in transforming growth factor β-mediated signaling. J Biol Chem 1997; 272:1429-32.
    • (1997) J Biol Chem , vol.272 , pp. 1429-1432
    • Atfi, A.1    Djelloul, S.2    Chastre, E.3    Davis, R.4    Gespach, C.5
  • 25
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003; 425:577-84.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 26
    • 19944429743 scopus 로고    scopus 로고
    • Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH2-terminal kinase during human colorectal carcino-genesis
    • Yamagata H, Matsuzaki K, Mori S, Yoshida K, Tahashi Y, Furukawa F, et al. Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH2-terminal kinase during human colorectal carcino-genesis. Cancer Res 2005; 65:157-65.
    • (2005) Cancer Res , vol.65 , pp. 157-165
    • Yamagata, H.1    Matsuzaki, K.2    Mori, S.3    Yoshida, K.4    Tahashi, Y.5    Furukawa, F.6
  • 28
    • 0141953270 scopus 로고    scopus 로고
    • A JNK-dependent pathway is required for TNF alpha-induced apoptosis
    • Deng Y, Ren X, Yang L, Lin Y, Wu X. A JNK-dependent pathway is required for TNF alpha-induced apoptosis. Cell 2003; 115:61-70.
    • (2003) Cell , vol.115 , pp. 61-70
    • Deng, Y.1    Ren, X.2    Yang, L.3    Lin, Y.4    Wu, X.5
  • 29
    • 16844387124 scopus 로고    scopus 로고
    • Role of JNK activation in apoptosis: A double-edged sword
    • Liu J, Lin A. Role of JNK activation in apoptosis: a double-edged sword. Cell Res 2005; 15:36-42.
    • (2005) Cell Res , vol.15 , pp. 36-42
    • Liu, J.1    Lin, A.2
  • 30
    • 33846689276 scopus 로고    scopus 로고
    • A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis
    • Ma FY, Flanc RS, Tesch GH, Han Y, Atkins RC, Bennett BL, et al. A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis. J Am Soc Nephrol 2007; 18:472-84.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 472-484
    • Ma, F.Y.1    Flanc, R.S.2    Tesch, G.H.3    Han, Y.4    Atkins, R.C.5    Bennett, B.L.6
  • 31
    • 0037636775 scopus 로고    scopus 로고
    • 2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts
    • 2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts. Am J Respir Cell Mol Biol 2003; 28:754-61.
    • (2003) Am J Respir Cell Mol Biol , vol.28 , pp. 754-761
    • Utsugi, M.1    Dobashi, K.2    Ishizuka, T.3    Masubuchi, K.4    Shimizu, Y.5    Nakazawa, T.6
  • 32
    • 0042704734 scopus 로고    scopus 로고
    • Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells
    • Hayashida T, de Casestecker M, Schnaper HW. Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells. FASEB J 2003; 17:1576-8.
    • (2003) FASEB J , vol.17 , pp. 1576-1578
    • Hayashida, T.1    de Casestecker, M.2    Schnaper, H.W.3
  • 33
    • 20544437490 scopus 로고    scopus 로고
    • Role of reactive oxygen species in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
    • Rhyu DY, Yang Y, Ha H, Lee GT, Song JS, Uh ST, et al. Role of reactive oxygen species in TGF-β1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 2005; 16:667-75.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 667-675
    • Rhyu, D.Y.1    Yang, Y.2    Ha, H.3    Lee, G.T.4    Song, J.S.5    Uh, S.T.6
  • 34
    • 0141866937 scopus 로고    scopus 로고
    • p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts
    • Furukawa F, Matsuzaki K, Mori S, Tahashi Y, Yoshida K, Sugano Y, et al. p38 MAPK mediates fibrogenic signal through Smad3 phosphorylation in rat myofibroblasts. Hepatology 2003; 38:879-89.
    • (2003) Hepatology , vol.38 , pp. 879-889
    • Furukawa, F.1    Matsuzaki, K.2    Mori, S.3    Tahashi, Y.4    Yoshida, K.5    Sugano, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.