-
1
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin C.-H., Miyazono K., ten Dijke P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature. 390:1997;465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
2
-
-
0031685620
-
TGF-β signal transduction
-
Massagué J. TGF-β signal transduction. Annu. Rev. Biochem. 67:1998;753-791.
-
(1998)
Annu. Rev. Biochem.
, vol.67
, pp. 753-791
-
-
Massagué, J.1
-
4
-
-
0027946689
-
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage
-
Katagiri T., Yamaguchi A., Komaki M., Abe E., Takahashi N., Ikeda T., Rosen V., Wozney J.M., Fujisawa-Sehara A., Suda T. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J. Cell. Biol. 127:1994;1755-1766.
-
(1994)
J. Cell. Biol.
, vol.127
, pp. 1755-1766
-
-
Katagiri, T.1
Yamaguchi, A.2
Komaki, M.3
Abe, E.4
Takahashi, N.5
Ikeda, T.6
Rosen, V.7
Wozney, J.M.8
Fujisawa-Sehara, A.9
Suda, T.10
-
5
-
-
0032479303
-
Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA
-
Takeda K., Ichijo H., Fujii M., Mochida Y., Saitoh M., Nishitoh H., Sampath T.K., Miyazono K. Identification of a novel bone morphogenetic protein-responsive gene that may function as a noncoding RNA. J. Biol. Chem. 273:1998;17,079-17,085.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17079-17085
-
-
Takeda, K.1
Ichijo, H.2
Fujii, M.3
Mochida, Y.4
Saitoh, M.5
Nishitoh, H.6
Sampath, T.K.7
Miyazono, K.8
-
6
-
-
0032754669
-
Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation
-
Ebisawa T., Tada K., Kitajima I., Tojo A., Samapth T.K., Kawabata M., Miyazono K., Imamura T. Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation. J. Cell. Sci. 112:1999;3519-3527.
-
(1999)
J. Cell. Sci.
, vol.112
, pp. 3519-3527
-
-
Ebisawa, T.1
Tada, K.2
Kitajima, I.3
Tojo, A.4
Samapth, T.K.5
Kawabata, M.6
Miyazono, K.7
Imamura, T.8
-
7
-
-
0032718990
-
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblastic and chondroblastic differentiation
-
Fujii M, Takeda K, Imamura T, Sampath TK, Enomoto S, Kawabata M, Kato M, Ichijo H, Miyazono K. Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblastic and chondroblastic differentiation. Mol Biol Cell 1999;10:3801-13
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3801-3813
-
-
Fujii, M.1
Takeda, K.2
Imamura, T.3
Sampath, T.K.4
Enomoto, S.5
Kawabata, M.6
Kato, M.7
Ichijo, H.8
Miyazono, K.9
-
9
-
-
0028332818
-
Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
-
ten Dijke P., Yamashita H., Sampath T.K., Reddi A.H., Estevez M., Riddle D.L., Ichijo H., Heldin C.-H., Miyazono K. Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J. Biol. Chem. 269:1994;16,985-16,988.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16985-16988
-
-
Ten Dijke, P.1
Yamashita, H.2
Sampath, T.K.3
Reddi, A.H.4
Estevez, M.5
Riddle, D.L.6
Ichijo, H.7
Heldin, C.-H.8
Miyazono, K.9
-
10
-
-
0032475884
-
Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
-
Macías-Silva M., Hoodless P.A., Tang S.J., Buchwald M., Wrana J.L. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J. Biol. Chem. 273:1998;25,628-25,636.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25628-25636
-
-
MacÍas-Silva, M.1
Hoodless, P.A.2
Tang, S.J.3
Buchwald, M.4
Wrana, J.L.5
-
11
-
-
0032582672
-
Transforming growth factor β1 induces nuclear export of inhibitory Smad7
-
Itoh S., Landström M., Hermansson A., Itoh F., Heldin C.-H., Heldin N.-E., ten Dijke P. Transforming growth factor β1 induces nuclear export of inhibitory Smad7. J. Biol. Chem. 273:1998;29,195-29,201.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29195-29201
-
-
Itoh, S.1
Landström, M.2
Hermansson, A.3
Itoh, F.4
Heldin, C.-H.5
Heldin, N.-E.6
Ten Dijke, P.7
-
12
-
-
0029875398
-
Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: Differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
-
Shukunami C., Shigeno C., Atsumi T., Ishizeki K., Suzuki F., Hiraki Y. Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. J. Cell. Biol. 133:1996;457-468.
-
(1996)
J. Cell. Biol.
, vol.133
, pp. 457-468
-
-
Shukunami, C.1
Shigeno, C.2
Atsumi, T.3
Ishizeki, K.4
Suzuki, F.5
Hiraki, Y.6
-
13
-
-
0027360838
-
Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria
-
Asahina I., Sampath T.K., Nishimura I., Hauschka P.V. Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria. J. Cell. Biol. 123:1993;921-933.
-
(1993)
J. Cell. Biol.
, vol.123
, pp. 921-933
-
-
Asahina, I.1
Sampath, T.K.2
Nishimura, I.3
Hauschka, P.V.4
-
14
-
-
0033178337
-
P38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells
-
Nakamura K., Shirai T., Morishita S., Uchida S., Saeki-Miura K., Makishima F. p38 mitogen-activated protein kinase functionally contributes to chondrogenesis induced by growth/differentiation factor-5 in ATDC5 cells. Exp. Cell. Res. 250:1999;351-363.
-
(1999)
Exp. Cell. Res.
, vol.250
, pp. 351-363
-
-
Nakamura, K.1
Shirai, T.2
Morishita, S.3
Uchida, S.4
Saeki-Miura, K.5
Makishima, F.6
-
15
-
-
0032719815
-
Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice
-
Nakao A., Fujii M., Matsumura R., Kumano K., Saito Y., Miyazono K., Iwamoto I. Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice. J. Clin. Invest. 104:1999;5-11.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 5-11
-
-
Nakao, A.1
Fujii, M.2
Matsumura, R.3
Kumano, K.4
Saito, Y.5
Miyazono, K.6
Iwamoto, I.7
-
16
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel L., Le Dai J., Buckhaults P., Zhou S., Kinzler K.W., Vogelstein B., Kern S.E. Human Smad3 and Smad4 are sequence-specific transcription activators. Mol. Cell. 1:1998;611-617.
-
(1998)
Mol. Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Le Dai, J.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
Vogelstein, B.6
Kern, S.E.7
-
17
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler S., Itoh S., Vivien D., ten Dijke P., Huet S., Gauthier J.M. Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:1998;3091-3100.
-
(1998)
EMBO J.
, vol.17
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
18
-
-
0032516862
-
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer
-
Jonk L.J.C., Itoh S., Heldin C.-H., ten Dijke P., Kruijer W. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer. J. Biol. Chem. 273:1998;21,145-21,152.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21145-21152
-
-
Jonk, L.J.C.1
Itoh, S.2
Heldin, C.-H.3
Ten Dijke, P.4
Kruijer, W.5
-
19
-
-
0031889595
-
Characterization of MADH2/Smad2 gene, a human Mad homolog responsible for transforming growth factor-β And activin signal transduction pathway
-
Takenoshita S., Mogi A., Nagashima M., Yang K., Yagi K., Hanyu A., Nagamachi Y., Miyazono K., Hagiwara K. Characterization of MADH2/Smad2 gene, a human Mad homolog responsible for transforming growth factor-β and activin signal transduction pathway. Genomics. 48:1998;1-11.
-
(1998)
Genomics
, vol.48
, pp. 1-11
-
-
Takenoshita, S.1
Mogi, A.2
Nagashima, M.3
Yang, K.4
Yagi, K.5
Hanyu, A.6
Nagamachi, Y.7
Miyazono, K.8
Hagiwara, K.9
-
20
-
-
0033534573
-
Alternatively-spliced variant of Smad2 lacking exon 3: Comparison with wild-type Smad2 and Smad3
-
Yagi K., Goto D., Hamamoto T., Takenoshita S., Kato M., Miyazono K. Alternatively-spliced variant of Smad2 lacking exon 3: comparison with wild-type Smad2 and Smad3. J. Biol. Chem. 274:1999;703-709.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 703-709
-
-
Yagi, K.1
Goto, D.2
Hamamoto, T.3
Takenoshita, S.4
Kato, M.5
Miyazono, K.6
-
21
-
-
0033602186
-
A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3
-
Dennler S., Huet S., Gauthier J.M. A short amino-acid sequence in MH1 domain is responsible for functional differences between Smad2 and Smad3. Oncogene. 18:1999;1643-1648.
-
(1999)
Oncogene
, vol.18
, pp. 1643-1648
-
-
Dennler, S.1
Huet, S.2
Gauthier, J.M.3
-
22
-
-
0032110463
-
Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST2
-
Labbé E., Silvestri C., Hoodless P.A., Wrana J.L., Attisano L. Smad2 and Smad3 positively and negatively regulate TGFβ-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell. 2:1998;109-120.
-
(1998)
Mol. Cell
, vol.2
, pp. 109-120
-
-
Labbé, E.1
Silvestri, C.2
Hoodless, P.A.3
Wrana, J.L.4
Attisano, L.5
-
23
-
-
0033605129
-
Convergence of transforming growth factor-β And vitamin D signaling pathways on Smad transcriptional coactivators
-
Yanagisawa J., Yanagi Y., Masuhiro Y., Suzawa M., Toriyabe T., Kashiwagi K., Watanabe M., Kawabata M., Miyazono K., Kato S. Convergence of transforming growth factor-β and vitamin D signaling pathways on Smad transcriptional coactivators. Science. 283:1999;1317-1321.
-
(1999)
Science
, vol.283
, pp. 1317-1321
-
-
Yanagisawa, J.1
Yanagi, Y.2
Masuhiro, Y.3
Suzawa, M.4
Toriyabe, T.5
Kashiwagi, K.6
Watanabe, M.7
Kawabata, M.8
Miyazono, K.9
Kato, S.10
-
24
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori T., Yagi H., Nomura S., Yamaguchi A., Sasaki K., Deguchi K., et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 89:1997;755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
-
25
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto F., Thornell A.P., Crompton T., Denzel A., Gilmour K.C., Rosewell I.R., et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 89:1997;765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
-
26
-
-
0030061554
-
AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
-
Okuda T., van Deursen J., Hiebert S.W., Grosveld G., Downing J.R. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 84:1996;321-330.
-
(1996)
Cell
, vol.84
, pp. 321-330
-
-
Okuda, T.1
Van Deursen, J.2
Hiebert, S.W.3
Grosveld, G.4
Downing, J.R.5
-
27
-
-
0032534230
-
CBFα3 (AML2) is induced by TGF-β1 to bind and activate the mouse germline Ig α promoter
-
Shi M.J., Stavnezer J. CBFα3 (AML2) is induced by TGF-β1 to bind and activate the mouse germline Ig α promoter. J. Immunol. 161:1998;6751-6760.
-
(1998)
J. Immunol.
, vol.161
, pp. 6751-6760
-
-
Shi, M.J.1
Stavnezer, J.2
-
28
-
-
0039844411
-
Interaction and functional cooperation of PEBP2/CBF with Smads: Synergistic induction of the immunoglobulin germline Cα promoter
-
Hanai J.-i, Chen L.F., Kanno T., Ohtani-Fujita N., Kim W.Y., Guo W.-H., et al. Interaction and functional cooperation of PEBP2/CBF with Smads: synergistic induction of the immunoglobulin germline Cα promoter. J. Biol. Chem. 274:1999;31,577-31,582.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31577-31582
-
-
Hanai, J.-i.1
Chen, L.F.2
Kanno, T.3
Ohtani-Fujita, N.4
Kim, W.Y.5
Guo, W.-H.6
-
29
-
-
0034603004
-
Smad and AML proteins synergistically confer TGFβ1 responsiveness of human germ-line IgA genes
-
in press
-
Pardali E, Xie X-Q, Itoh S, Konstantinos A, Panagiotis T, Heldin C-H, Ten Dijke P, Grundström T, Sideras P. Smad and AML proteins synergistically confer TGFβ1 responsiveness of human germ-line IgA genes. J Biol Chem (in press), 2000
-
(2000)
J Biol Chem
-
-
Pardali, E.1
Xie, X.-Q.2
Itoh, S.3
Konstantinos, A.4
Panagiotis, T.5
Heldin, C.-H.6
Ten Dijke, P.7
Grundström, T.8
Sideras, P.9
-
30
-
-
0031741487
-
Role of p300, a transcriptional coactivator, in signalling of TGF-β
-
Nishihara A., Hanai J.-i, Okamoto N., Yanagisawa J., Kato S., Miyazono K., Kawabata M. Role of p300, a transcriptional coactivator, in signalling of TGF-β Gene Cells. 3:1998;613-623.
-
(1998)
Gene Cells
, vol.3
, pp. 613-623
-
-
Nishihara, A.1
Hanai, J.-i.2
Okamoto, N.3
Yanagisawa, J.4
Kato, S.5
Miyazono, K.6
Kawabata, M.7
-
31
-
-
0032528236
-
The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation
-
Feng X.-H., Zhang Y., Wu R.Y., Derynck R. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for Smad3 in TGF-β-induced transcriptional activation. Genes Dev. 12:1998;2153-2163.
-
(1998)
Genes Dev.
, vol.12
, pp. 2153-2163
-
-
Feng, X.-H.1
Zhang, Y.2
Wu, R.Y.3
Derynck, R.4
-
32
-
-
0032527756
-
TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300
-
Janknecht R., Wells N.J., Hunter T. TGF-β-stimulated cooperation of Smad proteins with the coactivators CBP/p300. Genes Dev. 12:1998;2114-2119.
-
(1998)
Genes Dev.
, vol.12
, pp. 2114-2119
-
-
Janknecht, R.1
Wells, N.J.2
Hunter, T.3
-
33
-
-
0032483493
-
Physical and functional interaction of Smads and p300/CBP
-
Pouponnot C., Jayaraman L., Massagué J. Physical and functional interaction of Smads and p300/CBP. J. Biol. Chem. 273:1998;22,865-22,868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 22865-22868
-
-
Pouponnot, C.1
Jayaraman, L.2
Massagué, J.3
-
34
-
-
0031773264
-
TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
-
Shen X., Hu P.P., Liberati N.T., Datto M.B., Frederick J.P., Wang X.-F. TGF-β-induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein. Mol. Biol. Cell. 9:1998;3309-3319.
-
(1998)
Mol. Biol. Cell.
, vol.9
, pp. 3309-3319
-
-
Shen, X.1
Hu, P.P.2
Liberati, N.T.3
Datto, M.B.4
Frederick, J.P.5
Wang, X.-F.6
-
35
-
-
0033214670
-
E1A inhibits transforming growth factor-β signaling through binding to Smad proteins
-
Nishihara A., Hanai J.-i, Imamura T., Miyazono K., Kawabata M. E1A inhibits transforming growth factor-β signaling through binding to Smad proteins. J. Biol. Chem. 274:1999;28,716-28,723.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28716-28723
-
-
Nishihara, A.1
Hanai, J.-i.2
Imamura, T.3
Miyazono, K.4
Kawabata, M.5
-
36
-
-
0033574767
-
Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300
-
Nakashima K., Yanagisawa M., Arakawa H., Kimura N., Hisatsune T., Kawabata M., Miyazono K., Taga T. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science. 284:1999;479-482.
-
(1999)
Science
, vol.284
, pp. 479-482
-
-
Nakashima, K.1
Yanagisawa, M.2
Arakawa, H.3
Kimura, N.4
Hisatsune, T.5
Kawabata, M.6
Miyazono, K.7
Taga, T.8
-
38
-
-
0033557497
-
Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor
-
Nomura T., Khan M.M., Kaul S.C., Dong H.-D., Wadhwa R., Colmenares C., Kohno I., Ishii I. Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor. Genes Dev. 13:1999;412-423.
-
(1999)
Genes Dev.
, vol.13
, pp. 412-423
-
-
Nomura, T.1
Khan, M.M.2
Kaul, S.C.3
Dong, H.-D.4
Wadhwa, R.5
Colmenares, C.6
Kohno, I.7
Ishii, I.8
-
39
-
-
0033521032
-
c-Ski acts as a transcriptional co-repressor in TGF-β signaling through interaction with Smads
-
Akiyoshi S, Inoue H, Hanai J-i, Kusanagi K, Nemoto N, Miyazono K, Kawabata M. c-Ski acts as a transcriptional co-repressor in TGF-β signaling through interaction with Smads. J Biol Chem 1999;274:35269-77
-
(1999)
J Biol Chem
, vol.274
, pp. 35269-35277
-
-
Akiyoshi, S.1
Inoue, H.2
Hanai, J.-I.3
Kusanagi, K.4
Nemoto, N.5
Miyazono, K.6
Kawabata, M.7
-
40
-
-
0033200361
-
The Ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling
-
Luo K., Stroschein S.L., Wang W., Chen D., Martens E., Zhou S., Zhou Q. The Ski oncoprotein interacts with the Smad proteins to repress TGF-β signaling. Genes Dev. 13:1999;2196-2206.
-
(1999)
Genes Dev.
, vol.13
, pp. 2196-2206
-
-
Luo, K.1
Stroschein, S.L.2
Wang, W.3
Chen, D.4
Martens, E.5
Zhou, S.6
Zhou, Q.7
-
41
-
-
0033213606
-
Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling
-
Sun Y., Liu X., Eaton E.N., Lane W.S., Lodish H.F., Weinberg R.A. Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling. Mol. Cell. 4:1999;499-509.
-
(1999)
Mol. Cell
, vol.4
, pp. 499-509
-
-
Sun, Y.1
Liu, X.2
Eaton, E.N.3
Lane, W.S.4
Lodish, H.F.5
Weinberg, R.A.6
-
42
-
-
0033595704
-
Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein
-
Stroschein S.L., Wang W., Zhou S., Zhou Q., Luo K. Negative feedback regulation of TGF-β signaling by the SnoN oncoprotein. Science. 286:1999;771-774.
-
(1999)
Science
, vol.286
, pp. 771-774
-
-
Stroschein, S.L.1
Wang, W.2
Zhou, S.3
Zhou, Q.4
Luo, K.5
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