-
1
-
-
0842281498
-
Aurora kinases link chromosome segregation and cell division to cancer susceptibility
-
Meraldi P, Honda R, Nigg EA. Aurora kinases link chromosome segregation and cell division to cancer susceptibility. Curr Opin Genet Dev 2004; 14: 29-36.
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 29-36
-
-
Meraldi, P.1
Honda, R.2
Nigg, E.A.3
-
2
-
-
0032716628
-
Aurora/Iplp-related kinases, a new oncogenic family of mitotic serine-threonine kinases
-
Giet R, Prigent C. Aurora/Iplp-related kinases, a new oncogenic family of mitotic serine-threonine kinases. J Cell Sci 1999; 112: 3591-3601.
-
(1999)
J Cell Sci
, vol.112
, pp. 3591-3601
-
-
Giet, R.1
Prigent, C.2
-
3
-
-
0034742120
-
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells
-
Sun M, Wang G, Paciga JE, Feldman RI, Yuan ZQ, Ma XL et al. AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol 2001; 159: 431-437.
-
(2001)
Am J Pathol
, vol.159
, pp. 431-437
-
-
Sun, M.1
Wang, G.2
Paciga, J.E.3
Feldman, R.I.4
Yuan, Z.Q.5
Ma, X.L.6
-
4
-
-
0036894571
-
Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft
-
Bar-Shira A, Pinthus JH, Rozovsky U, Goldstein M, Sellers WR, Yaron Y et al. Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft. Cancer Res 2002; 62: 6803-6807.
-
(2002)
Cancer Res
, vol.62
, pp. 6803-6807
-
-
Bar-Shira, A.1
Pinthus, J.H.2
Rozovsky, U.3
Goldstein, M.4
Sellers, W.R.5
Yaron, Y.6
-
5
-
-
33744911634
-
Targeting Aurora kinases for the treatment of prostate cancer
-
Lee EC, Frolov A, Li R, Ayala G, Greenberg NM. Targeting Aurora kinases for the treatment of prostate cancer. Cancer Res 2006; 66: 4996-5002.
-
(2006)
Cancer Res
, vol.66
, pp. 4996-5002
-
-
Lee, E.C.1
Frolov, A.2
Li, R.3
Ayala, G.4
Greenberg, N.M.5
-
6
-
-
33947728303
-
Effect of Aurora A on biological phenotypes of prostate cancer cells
-
Zhao FY, Qu Y, Zhang L, Mu DZ, Huang X, Wei DP. Effect of Aurora A on biological phenotypes of prostate cancer cells. Sichuan Da Xue Xue Bao Yi Xue Ban 2007; 38: 302-305.
-
(2007)
Sichuan Da Xue Xue Bao Yi Xue Ban
, vol.38
, pp. 302-305
-
-
Zhao, F.Y.1
Qu, Y.2
Zhang, L.3
Mu, D.Z.4
Huang, X.5
Wei, D.P.6
-
7
-
-
34247277243
-
DNAzymes as potential therapeutic molecules
-
Isaka Y. DNAzymes as potential therapeutic molecules. Curr Opin Mol Ther 2007; 9: 132-136.
-
(2007)
Curr Opin Mol Ther
, vol.9
, pp. 132-136
-
-
Isaka, Y.1
-
8
-
-
0344442416
-
RNA cleaving '10-23' DNAzymes with enhanced stability and activity
-
Schubert S, Gul DC, Grunert HP, Zeichhardt H, Erdmann VA, Kurreck J. RNA cleaving '10-23' DNAzymes with enhanced stability and activity. Nucleic Acids Res 2003; 31: 5982-5992.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5982-5992
-
-
Schubert, S.1
Gul, D.C.2
Grunert, H.P.3
Zeichhardt, H.4
Erdmann, V.A.5
Kurreck, J.6
-
9
-
-
10044261960
-
Ribozyme and deoxyribozyme strategies for medical applications
-
Sclhubert S, Kurreck J. Ribozyme and deoxyribozyme strategies for medical applications. Curr Drug Targets 2004; 5: 667-681.
-
(2004)
Curr Drug Targets
, vol.5
, pp. 667-681
-
-
Sclhubert, S.1
Kurreck, J.2
-
10
-
-
0035997959
-
DNAzymes: Cutting a path to a new class of therapeutics
-
Khachigian LM. DNAzymes: cutting a path to a new class of therapeutics. Curr Opin Mol Ther 2002; 4: 119-121.
-
(2002)
Curr Opin Mol Ther
, vol.4
, pp. 119-121
-
-
Khachigian, L.M.1
-
11
-
-
0038742950
-
Circadian telomerase activity and DNA synthesis for timing peptide administration
-
Qu Y, Wang Z, Huang X, Wan C, Yang CL, Liu B et al. Circadian telomerase activity and DNA synthesis for timing peptide administration. Peptides 2003; 24: 363-369.
-
(2003)
Peptides
, vol.24
, pp. 363-369
-
-
Qu, Y.1
Wang, Z.2
Huang, X.3
Wan, C.4
Yang, C.L.5
Liu, B.6
-
12
-
-
0141429171
-
Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells
-
Hirota T, Kunitoku N, Sasayama T, Marumoto T, Zhang D, Nitta M et al. Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells. Cell 2003; 114: 585-598.
-
(2003)
Cell
, vol.114
, pp. 585-598
-
-
Hirota, T.1
Kunitoku, N.2
Sasayama, T.3
Marumoto, T.4
Zhang, D.5
Nitta, M.6
-
13
-
-
1842816662
-
Aurora A, meiosis and mitosis
-
Crane R, Gadea B, Littlepage L, Wu H, Ruderman JV. Aurora A, meiosis and mitosis. Biol Cell 2004; 96: 215-229.
-
(2004)
Biol Cell
, vol.96
, pp. 215-229
-
-
Crane, R.1
Gadea, B.2
Littlepage, L.3
Wu, H.4
Ruderman, J.V.5
-
15
-
-
10344236486
-
Aurora-kinase inhibitors as anticancer agents
-
Keen N, Taylor S. Aurora-kinase inhibitors as anticancer agents. Nat Rev Cancer 2004; 4: 927-936.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 927-936
-
-
Keen, N.1
Taylor, S.2
-
16
-
-
0037048279
-
On the role of Aurora A in centrosome function
-
Dutertre S, Descamps S, Prigent C. On the role of Aurora A in centrosome function. Oncogene 2002; 21: 6175-6183.
-
(2002)
Oncogene
, vol.21
, pp. 6175-6183
-
-
Dutertre, S.1
Descamps, S.2
Prigent, C.3
-
17
-
-
0035839605
-
pEg2 Aurora-A kinase, histone H3 phosphorylation, and chromosome assembly in xenopus egg extract
-
Scrittori L, Hans F, Angelov D, Charra M, Prigent C, Dimitrov S. pEg2 Aurora-A kinase, histone H3 phosphorylation, and chromosome assembly in xenopus egg extract. J Biol Chem 2001; 276: 30002-30010.
-
(2001)
J Biol Chem
, vol.276
, pp. 30002-30010
-
-
Scrittori, L.1
Hans, F.2
Angelov, D.3
Charra, M.4
Prigent, C.5
Dimitrov, S.6
-
18
-
-
0036565678
-
N-Methyl-Daspartate recepter signaling results in Aurora kinase-catalyzed CPEB phosphorylation and CaMKII mRNA polyadenylation at synapses
-
Huang YS, Jung MY, Sarkissian M, Richter JD. N-Methyl-Daspartate recepter signaling results in Aurora kinase-catalyzed CPEB phosphorylation and CaMKII mRNA polyadenylation at synapses. EMBO J 2002; 21: 2139-2148.
-
(2002)
EMBO J
, vol.21
, pp. 2139-2148
-
-
Huang, Y.S.1
Jung, M.Y.2
Sarkissian, M.3
Richter, J.D.4
-
19
-
-
0037017398
-
Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules
-
Giet R, McLean D, Descamps S, Lee MJ, Raff JW, Prigent C et al. Drosophila Aurora A kinase is required to localize D-TACC to centrosomes and to regulate astral microtubules. J Cell Biol 2002; 156: 437-451.
-
(2002)
J Cell Biol
, vol.156
, pp. 437-451
-
-
Giet, R.1
McLean, D.2
Descamps, S.3
Lee, M.J.4
Raff, J.W.5
Prigent, C.6
-
20
-
-
0037462726
-
Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes
-
Gastro A, Mandart E, Lorca T, Galas S. Involvement of Aurora A kinase during meiosis I-II transition in Xenopus oocytes. J Biol Chem 2003; 278: 2236-2241.
-
(2003)
J Biol Chem
, vol.278
, pp. 2236-2241
-
-
Gastro, A.1
Mandart, E.2
Lorca, T.3
Galas, S.4
-
21
-
-
0037135979
-
Human TPX2 is required for targeting Aurora-A kinase to the spindle
-
Kufer TA, Sillje HH, Korner R, Gruss OJ, Meraldi P, Nigg EA. Human TPX2 is required for targeting Aurora-A kinase to the spindle. J Cell Biol 2002; 158: 617-623.
-
(2002)
J Cell Biol
, vol.158
, pp. 617-623
-
-
Kufer, T.A.1
Sillje, H.H.2
Korner, R.3
Gruss, O.J.4
Meraldi, P.5
Nigg, E.A.6
-
22
-
-
25444470823
-
CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage
-
Cazales M, Schmitt E, Montembault E, Dozier C, Prigent C, Ducommun B. CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage. Cell Cycle 2005; 4: 1233-1238.
-
(2005)
Cell Cycle
, vol.4
, pp. 1233-1238
-
-
Cazales, M.1
Schmitt, E.2
Montembault, E.3
Dozier, C.4
Prigent, C.5
Ducommun, B.6
-
23
-
-
1642556824
-
Aurora A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells
-
Yang H, Ou CC, Feldman RI, Nicosia SV, Kruk PA, Cheng JQ. Aurora A kinase regulates telomerase activity through c-Myc in human ovarian and breast epithelial cells. Cancer Res 2004; 64: 463-467.
-
(2004)
Cancer Res
, vol.64
, pp. 463-467
-
-
Yang, H.1
Ou, C.C.2
Feldman, R.I.3
Nicosia, S.V.4
Kruk, P.A.5
Cheng, J.Q.6
-
24
-
-
0038701811
-
Telomerase inhibition as cancer therapy
-
Saretzki G. Telomerase inhibition as cancer therapy. Cancer Lett 2003; 194: 209-219.
-
(2003)
Cancer Lett
, vol.194
, pp. 209-219
-
-
Saretzki, G.1
-
25
-
-
20144373746
-
194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening
-
194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening. J Biol Chem 2005; 280: 9013-9022.
-
(2005)
J Biol Chem
, vol.280
, pp. 9013-9022
-
-
Wu, J.C.1
Chen, T.Y.2
Yu, C.T.3
Tsai, S.J.4
Hsu, J.M.5
Tang, M.J.6
-
26
-
-
35948938922
-
Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells
-
Guan Z, Wang XR, Zhu XF, Huang XF, Xu J, Wang LH et al. Aurora-A, a negative prognostic marker, increases migration and decreases radiosensitivity in cancer cells. Cancer Res 2007; 67: 10436-10444.
-
(2007)
Cancer Res
, vol.67
, pp. 10436-10444
-
-
Guan, Z.1
Wang, X.R.2
Zhu, X.F.3
Huang, X.F.4
Xu, J.5
Wang, L.H.6
-
27
-
-
0032408639
-
Identification and characterization of STK12/Aik2: A human gene related to Aurora of Drosophila and yeast IPL1
-
Kimura M, Matsuda Y, Yoshioka T, Sumi N, Okano Y. Identification and characterization of STK12/Aik2: a human gene related to Aurora of Drosophila and yeast IPL1. Cytogenet Cell Genet 1998; 82: 147-152.
-
(1998)
Cytogenet Cell Genet
, vol.82
, pp. 147-152
-
-
Kimura, M.1
Matsuda, Y.2
Yoshioka, T.3
Sumi, N.4
Okano, Y.5
-
28
-
-
2342639645
-
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo
-
Harrington EA, Bebbington D, Moore J, Rasmussen RK, Ajose-Adeogun AO, Nakayama T et al. VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat Med 2004; 10: 262-267.
-
(2004)
Nat Med
, vol.10
, pp. 262-267
-
-
Harrington, E.A.1
Bebbington, D.2
Moore, J.3
Rasmussen, R.K.4
Ajose-Adeogun, A.O.5
Nakayama, T.6
-
29
-
-
34247259822
-
Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase
-
Manfredi MG, Ecsedy JA, Meetze KA, Balani SK, Burenkova O, Chen W et al. Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase. Proc Natl Acad Sci USA 2007; 104: 4106-4111.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4106-4111
-
-
Manfredi, M.G.1
Ecsedy, J.A.2
Meetze, K.A.3
Balani, S.K.4
Burenkova, O.5
Chen, W.6
-
30
-
-
16844366286
-
RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells
-
Hata T, Furukawa T, Sunamura M, Egawa S, Motoi F, Ohmura N et al. RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells. Cancer Res 2005; 65: 2899-2905.
-
(2005)
Cancer Res
, vol.65
, pp. 2899-2905
-
-
Hata, T.1
Furukawa, T.2
Sunamura, M.3
Egawa, S.4
Motoi, F.5
Ohmura, N.6
-
31
-
-
32344450506
-
Preclinical anticancer activity of DNA-based cleavage molecules
-
Dass CR. Preclinical anticancer activity of DNA-based cleavage molecules. Drug Dev Ind Pharm 2006; 32: 1-5.
-
(2006)
Drug Dev Ind Pharm
, vol.32
, pp. 1-5
-
-
Dass, C.R.1
|