RNA cleaving '10-23' DNAzymes with enhanced stability and activity

Nucleic Acids Research

Volumn 31, Issue 20, 2003, Pages 5982-5992

  Schubert, Steffen ^a   Gül, Deniz C ^a   Grunert, Hans Peter ^a   Zeichhardt, Heinz ^a   Erdmann, Volker A ^a   Kurreck, Jens ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBOZYME; ENDONUCLEASE; NUCLEASE; NUCLEOTIDE; PHOSPHOROTHIOIC ACID; RNA DERIVATIVE; THYMIDINE; VIRUS RNA;

5' UNTRANSLATED REGION; ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL MODIFICATION; CONTROLLED STUDY; DNA MODIFICATION; DRUG ACTIVITY; DRUG DESIGN; DRUG FORMULATION; DRUG SPECIFICITY; DRUG STABILITY; DRUG STRUCTURE; DRUG TARGETING; ENZYMATIC DEGRADATION; HUMAN RHINOVIRUS; IN VIVO STUDY; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RNA CLEAVAGE; RNA SEQUENCE;

ASPERGILLUS NUCLEASE S1; BINDING SITES; CATALYTIC DOMAIN; DNA, CATALYTIC; DNA, SINGLE-STRANDED; ENZYME STABILITY; HUMANS; KINETICS; MUTATION; NUCLEIC ACID DENATURATION; OLIGORIBONUCLEOTIDES; RHINOVIRUS; RNA, VIRAL; SUBSTRATE SPECIFICITY; TEMPERATURE;

HUMAN RHINOVIRUS 14; HUMAN RHINOVIRUS SP.; RHINOVIRUS; RNA VIRUSES;

EID: 0344442416     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg791     Document Type: Article

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