메뉴 건너뛰기




Volumn 26, Issue 7, 2008, Pages 708-717

Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARγ

Author keywords

FOH; GGOH; GW9662; HCT116 cells; HT 29 cells; PPAR

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; CASPASE 3; FARNESOL; GERANYLGERANIOL; ISOPRENALINE; ISOPRENOID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN BCL XL; SURVIVIN;

EID: 48249118758     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900801898656     Document Type: Article
Times cited : (28)

References (36)
  • 1
    • 0025060806 scopus 로고
    • Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma
    • Moertel, C.G.; Fleming, T.R.; Macdonald, J.S.; et al. Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma. N Engl J Med 1990, 22, 352-358.
    • (1990) N Engl J Med , vol.22 , pp. 352-358
    • Moertel, C.G.1    Fleming, T.R.2    Macdonald, J.S.3
  • 2
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • De Gramont, A.; Figer, A.; Seymour, M.; et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000, 18, 2938-2947.
    • (2000) J Clin Oncol , vol.18 , pp. 2938-2947
    • De Gramont, A.1    Figer, A.2    Seymour, M.3
  • 3
    • 34447345960 scopus 로고    scopus 로고
    • Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft
    • Tin, M.M.; Cho, C.H.; Chan, K.; James, A.E.; Ko, J.K. Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft. Carcinogen 2007, 28, 1347-1355.
    • (2007) Carcinogen , vol.28 , pp. 1347-1355
    • Tin, M.M.1    Cho, C.H.2    Chan, K.3    James, A.E.4    Ko, J.K.5
  • 4
    • 33847069296 scopus 로고    scopus 로고
    • Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene
    • Ko, J.K.; Leung, W.C.; Ho, W.K.; Chiu, P. Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene. Eur J Pharmacol 2007, 559, 1-13.
    • (2007) Eur J Pharmacol , vol.559 , pp. 1-13
    • Ko, J.K.1    Leung, W.C.2    Ho, W.K.3    Chiu, P.4
  • 5
    • 0030846307 scopus 로고    scopus 로고
    • Creating isoprenoid diversity
    • Sacchettini, J.C.; Poulter, C.D.. Creating isoprenoid diversity. Science. 1997, 277, 1788-1789.
    • (1997) Science , vol.277 , pp. 1788-1789
    • Sacchettini, J.C.1    Poulter, C.D.2
  • 6
    • 0032851111 scopus 로고    scopus 로고
    • Sterols and isoprenoids: Signaling molecules derived from the cholesterol biosynthetic pathway
    • Edwards, P.A.; Ericsson J. Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Ann Rev Biochem 1999, 68, 157-185.
    • (1999) Ann Rev Biochem , vol.68 , pp. 157-185
    • Edwards, P.A.1    Ericsson, J.2
  • 7
    • 0028128625 scopus 로고
    • Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: Effect of phosphatidylcholine
    • Haug, J.S., Goldner, C.M.; Yazlovitskaya, E.M.; Voziyan, P.A.; Melnykovych, G. Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: effect of phosphatidylcholine. Biochim Biophys Acta 1994, 1223, 133-140.
    • (1994) Biochim Biophys Acta , vol.1223 , pp. 133-140
    • Haug, J.S.1    Goldner, C.M.2    Yazlovitskaya, E.M.3    Voziyan, P.A.4    Melnykovych, G.5
  • 9
    • 0030598825 scopus 로고    scopus 로고
    • Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells
    • Miquel, K.; Pradines, A.; Favre, G. Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells. Biochem Biophys Res Commun 1996, 225, 869-876.
    • (1996) Biochem Biophys Res Commun , vol.225 , pp. 869-876
    • Miquel, K.1    Pradines, A.2    Favre, G.3
  • 10
    • 0031589963 scopus 로고    scopus 로고
    • Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells
    • Masuda, Y.; Nakaya, M.; Nakajo, S.; Nakaya, K. Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells. Biochem Biophys Res Commun 1997, 234, 641-645.
    • (1997) Biochem Biophys Res Commun , vol.234 , pp. 641-645
    • Masuda, Y.1    Nakaya, M.2    Nakajo, S.3    Nakaya, K.4
  • 11
    • 0034792075 scopus 로고    scopus 로고
    • Geranylgeraniol, an intermediate product in mevalonate pathway, induces apoptotic cell death in human hepatoma cells: Death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression
    • Takeda, Y.; Nakao, K.; Nakata, K.; et al. Geranylgeraniol, an intermediate product in mevalonate pathway, induces apoptotic cell death in human hepatoma cells: death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression. Jpn J Cancer Res 2001, 92, 918-925.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 918-925
    • Takeda, Y.1    Nakao, K.2    Nakata, K.3
  • 12
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann, I.; Green, S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347, 645-650.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 13
    • 0034678088 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Insight into multiple cellular functions
    • Escher, P.; Wahli, W. Peroxisome proliferator-activated receptors: insight into multiple cellular functions. Mutat Res 2000, 448, 121-138.
    • (2000) Mutat Res , vol.448 , pp. 121-138
    • Escher, P.1    Wahli, W.2
  • 14
    • 0033849091 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors in tumorigenesis: Targets of tumour promotion and treatment
    • Roberts-Thomson, S.J. Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment. Immunol Cell Biol 2000, 78, 436-441.
    • (2000) Immunol Cell Biol , vol.78 , pp. 436-441
    • Roberts-Thomson, S.J.1
  • 15
    • 0036077277 scopus 로고    scopus 로고
    • Controversy: PPARgamma as a target for treatment of colorectal cancer
    • Gupta, R.A.; Dubois, R.N. Controversy: PPARgamma as a target for treatment of colorectal cancer. Am J Physiol Gastrointest Liver Physiol 2002, 283, G266-G269.
    • (2002) Am J Physiol Gastrointest Liver Physiol , vol.283
    • Gupta, R.A.1    Dubois, R.N.2
  • 16
    • 0033741281 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists
    • Sato, H.; Ishihara, S.; Kawashima, K.; et al. Expression of peroxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPARgamma agonists. Br J Cancer 2000, 83, 1394-1400.
    • (2000) Br J Cancer , vol.83 , pp. 1394-1400
    • Sato, H.1    Ishihara, S.2    Kawashima, K.3
  • 17
    • 13944280963 scopus 로고    scopus 로고
    • Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma
    • Shiau, C.W.; Yang, C.C.; Kulp, S.K. et al. Thiazolidenediones mediate apoptosis in prostate cancer cells in part through inhibition of Bcl-xL/Bcl-2 functions independently of PPARgamma. Cancer Res 2005, 65, 1561-1569.
    • (2005) Cancer Res , vol.65 , pp. 1561-1569
    • Shiau, C.W.1    Yang, C.C.2    Kulp, S.K.3
  • 18
    • 1542305504 scopus 로고    scopus 로고
    • Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma
    • Perez-Ortiz, J.M.; Tranque, P.; Vaquero, C.F.; et al. Glitazones differentially regulate primary astrocyte and glioma cell survival. Involvement of reactive oxygen species and peroxisome proliferator-activated receptor-gamma. J Biol Chem 2004, 279, 8976-8985.
    • (2004) J Biol Chem , vol.279 , pp. 8976-8985
    • Perez-Ortiz, J.M.1    Tranque, P.2    Vaquero, C.F.3
  • 19
    • 0036847134 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells
    • Clay, C.E.; Monjazeb, A.; Thorburn, J.; Chilton, F.H. High KP. 15-Deoxy-delta 12,14-prostaglandin J2-induced apoptosis does not require PPARgamma in breast cancer cells. J Lipid Res 2002, 43, 1818-1828.
    • (2002) J Lipid Res , vol.43 , pp. 1818-1828
    • Clay, C.E.1    Monjazeb, A.2    Thorburn, J.3    Chilton, F.H.4    High, K.P.5
  • 20
    • 18344374193 scopus 로고    scopus 로고
    • Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes
    • Takahashi, N.; Kawada, T.; Goto, T.; et al. Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes. FEBS Lett 2002, 514, 315-322.
    • (2002) FEBS Lett , vol.514 , pp. 315-322
    • Takahashi, N.1    Kawada, T.2    Goto, T.3
  • 21
    • 0028245326 scopus 로고
    • A rapid colorimetric assay of killer toxin activity in yeast
    • Hodgson, V.J.; Walker, G.M.; Button, D. A rapid colorimetric assay of killer toxin activity in yeast. FEMS Microbiol Lett 1994, 120, 201-205.
    • (1994) FEMS Microbiol Lett , vol.120 , pp. 201-205
    • Hodgson, V.J.1    Walker, G.M.2    Button, D.3
  • 22
    • 0027214910 scopus 로고
    • Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression
    • Marcus, S.L.; Miyata, K.S.; Zhang, B.; Subramani, S.; Rachubinski, R.A.; Capone, J.P. Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression. Proc Natl Acad Sci USA 1993, 90, 5723-5727.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5723-5727
    • Marcus, S.L.1    Miyata, K.S.2    Zhang, B.3    Subramani, S.4    Rachubinski, R.A.5    Capone, J.P.6
  • 23
    • 0036449793 scopus 로고    scopus 로고
    • Current status of the molecular mechanisms of anticancer drug-induced apoptosis
    • Kim, R.; Tanabe, K.; Uchida, Y.; Emi, M.; Inoue, H.; Toge, T. Current status of the molecular mechanisms of anticancer drug-induced apoptosis, Cancer Chemother Pharmacol 2002, 50, 343-352.
    • (2002) Cancer Chemother Pharmacol , vol.50 , pp. 343-352
    • Kim, R.1    Tanabe, K.2    Uchida, Y.3    Emi, M.4    Inoue, H.5    Toge, T.6
  • 24
    • 1542357606 scopus 로고    scopus 로고
    • Apoptosis pathways in cancer and cancer therapy
    • Debatin, K.M. Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother 2004, 53, 153-159.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 153-159
    • Debatin, K.M.1
  • 25
    • 9244251125 scopus 로고    scopus 로고
    • Cell-cycle checkpoints and cancer
    • Kastan, M.B.; Bartek, J. Cell-cycle checkpoints and cancer. Nature 2004, 432, 316-323.
    • (2004) Nature , vol.432 , pp. 316-323
    • Kastan, M.B.1    Bartek, J.2
  • 26
    • 0033026714 scopus 로고    scopus 로고
    • Mechanisms of apoptosis avoidance in cancer
    • Reed, J.C.; Mechanisms of apoptosis avoidance in cancer. Curr Opin Oncol 1999, 11, 68-75
    • (1999) Curr Opin Oncol , vol.11 , pp. 68-75
    • Reed, J.C.1
  • 27
    • 34249948005 scopus 로고    scopus 로고
    • Present concepts and future outlook: Function of peroxisome proliferator-activated receptors (PPARs) for pathogenesis, progression, and therapy of cancer
    • Sertznig, P.; Seifert, M., Tilgen, W., Reichrath, J. Present concepts and future outlook: Function of peroxisome proliferator-activated receptors (PPARs) for pathogenesis, progression, and therapy of cancer. J Cell Physiol 2007, 212, 1-12.
    • (2007) J Cell Physiol , vol.212 , pp. 1-12
    • Sertznig, P.1    Seifert, M.2    Tilgen, W.3    Reichrath, J.4
  • 28
    • 0037235020 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and cancers
    • Koeffler, H.P. Peroxisome proliferator-activated receptor gamma and cancers. Clin Cancer Res 2003, 9, 1-9.
    • (2003) Clin Cancer Res , vol.9 , pp. 1-9
    • Koeffler, H.P.1
  • 29
    • 0037134255 scopus 로고    scopus 로고
    • Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer
    • Chen, G.G.; Lee, J.F.; Wang, S.H.; Chan, U.P.; Ip, P.C.; Lau, W.Y. Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer. Life Sci 2002, 70, 2631-2646.
    • (2002) Life Sci , vol.70 , pp. 2631-2646
    • Chen, G.G.1    Lee, J.F.2    Wang, S.H.3    Chan, U.P.4    Ip, P.C.5    Lau, W.Y.6
  • 30
    • 0031694577 scopus 로고    scopus 로고
    • Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice
    • Lefebvre, A.M.; Chen, I.; Desreumaux, P.; et al. Activation of the peroxisome proliferator-activated receptor gamma promotes the development of colon tumors in C57BL/6J-APCMin/+ mice. Nat Med 1998, 4, 1053-1057.
    • (1998) Nat Med , vol.4 , pp. 1053-1057
    • Lefebvre, A.M.1    Chen, I.2    Desreumaux, P.3
  • 32
    • 0037458680 scopus 로고    scopus 로고
    • Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its antitumorigenic activity
    • Baek, S.J.; Wilson, L.C.; His, L.C.; Eling, T.E. Troglitazone, a peroxisome proliferator-activated receptor gamma (PPAR gamma) ligand, selectively induces the early growth response-1 gene independently of PPAR gamma. A novel mechanism for its antitumorigenic activity. J Biol Chem 2003, 278, 5845-53
    • (2003) J Biol Chem , vol.278 , pp. 5845-5853
    • Baek, S.J.1    Wilson, L.C.2    His, L.C.3    Eling, T.E.4
  • 33
    • 0034967914 scopus 로고    scopus 로고
    • Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells
    • Carnesecchi, S.; Schneider, Y.; Ceraline, J.; et al. Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells. J Pharmacol Exp Ther 2001, 298, 197-200.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 197-200
    • Carnesecchi, S.1    Schneider, Y.2    Ceraline, J.3
  • 34
    • 0030950694 scopus 로고    scopus 로고
    • Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo
    • He, L.; Mo, H.; Hadisusilo, S.; Qureshi, A.A.; Elson, C.E. Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo. J Nutr 1997, 127, 668-674.
    • (1997) J Nutr , vol.127 , pp. 668-674
    • He, L.1    Mo, H.2    Hadisusilo, S.3    Qureshi, A.A.4    Elson, C.E.5
  • 35
    • 0034847431 scopus 로고    scopus 로고
    • Prospects for prevention and treatment of cancer with selective PPARγ modulators (SPARMs)
    • Sporn, M.B.; Suh, N.; Mangelsdorf, D.J. Prospects for prevention and treatment of cancer with selective PPARγ modulators (SPARMs). Trends Mol Med 2001, 7, 395-400.
    • (2001) Trends Mol Med , vol.7 , pp. 395-400
    • Sporn, M.B.1    Suh, N.2    Mangelsdorf, D.J.3
  • 36
    • 7944225005 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ-dependent and -independent growth inhibition of gastrointestinal tumor cells
    • Rumi, M.A.K; Ishihara, S., Kadowaki, Y.; et al. Peroxisome proliferator-activated receptor γ-dependent and -independent growth inhibition of gastrointestinal tumor cells. Genes Cells 2004, 9, 1113-1123.
    • (2004) Genes Cells , vol.9 , pp. 1113-1123
    • Rumi, M.A.K.1    Ishihara, S.2    Kadowaki, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.