-
1
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterization of complementary DNA
-
Riordan JR, Rommens JM, Kerem B, et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245: 1066-1073 (1989).
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
Rommens, J.M.2
Kerem, B.3
-
2
-
-
20444366909
-
The gallbladder and biliary tract in cystic fibrosis
-
Curry MP, Hegarty JE. The gallbladder and biliary tract in cystic fibrosis. Curr Gastroenterol Rep 7(2): 147-53 (2005).
-
(2005)
Curr Gastroenterol Rep
, vol.7
, Issue.2
, pp. 147-153
-
-
Curry, M.P.1
Hegarty, J.E.2
-
3
-
-
0022413731
-
A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7
-
Knowlton RG, Cohen-Haguenauer O, Van Cong N, et al. A polymorphic DNA marker linked to cystic fibrosis is located on chromosome 7. Nature 318: 380-382 (1985).
-
(1985)
Nature
, vol.318
, pp. 380-382
-
-
Knowlton, R.G.1
Cohen-Haguenauer, O.2
Van Cong, N.3
-
4
-
-
0022361686
-
A closely linked genetic marker for cystic fibrosis
-
White R, Woodward S, Leppert M et al. A closely linked genetic marker for cystic fibrosis. Nature 318: 382-384 (1985).
-
(1985)
Nature
, vol.318
, pp. 382-384
-
-
White, R.1
Woodward, S.2
Leppert, M.3
-
5
-
-
0022385943
-
Localization of cystic fibrosis locus to human chromosome 7cen-q22
-
Wainwright BJ, Scambler PJ, Schmodtke J, et al. Localization of cystic fibrosis locus to human chromosome 7cen-q22. Nature 318: 384-385 (1985).
-
(1985)
Nature
, vol.318
, pp. 384-385
-
-
Wainwright, B.J.1
Scambler, P.J.2
Schmodtke, J.3
-
6
-
-
0024423668
-
Identification of the cystic fibrosis gene: Genetic analysis
-
Kerem B, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: Genetic analysis. Science 245:1073-1079 (1989).
-
(1989)
Science
, vol.245
, pp. 1073-1079
-
-
Kerem, B.1
Rommens, J.M.2
Buchanan, J.A.3
-
7
-
-
27544434744
-
Developmental paradigm for early features of cystic fibrosis
-
Larson JE, Cohen JC. Developmental paradigm for early features of cystic fibrosis. Pediatr Pulmonol 40(5): 371-377 (2005).
-
(2005)
Pediatr Pulmonol
, vol.40
, Issue.5
, pp. 371-377
-
-
Larson, J.E.1
Cohen, J.C.2
-
8
-
-
0032433707
-
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
-
Matsui H, Grubb BR, Tarran R, et al. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease. Cell 95: 1005-1015 (1998).
-
(1998)
Cell
, vol.95
, pp. 1005-1015
-
-
Matsui, H.1
Grubb, B.R.2
Tarran, R.3
-
9
-
-
0028920643
-
Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface
-
Imundo L, Barasch J, Prince A, Al-Awqati Q. Cystic fibrosis epithelial cells have a receptor for pathogenic bacteria on their apical surface. Proc Natl Acad Sci USA 92: 3019-3023 (1995).
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3019-3023
-
-
Imundo, L.1
Barasch, J.2
Prince, A.3
Al-Awqati, Q.4
-
10
-
-
0026523829
-
Cystic fibrosis: Molecular biology and therapeutic implications
-
Collins FS. Cystic fibrosis: molecular biology and therapeutic implications. Science 256(5058): 774-779 (1992).
-
(1992)
Science
, vol.256
, Issue.5058
, pp. 774-779
-
-
Collins, F.S.1
-
11
-
-
0026918861
-
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis
-
Johnson L, Olsen J, Sarkadi B, et al. Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis. Nat Genet 2: 21-5 (1992).
-
(1992)
Nat Genet
, vol.2
, pp. 21-25
-
-
Johnson, L.1
Olsen, J.2
Sarkadi, B.3
-
12
-
-
0036846329
-
Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis
-
Ramalho AS, Beck S, Meyer M, et al. Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis. Am J Respir Cell Mol Biol 5: 619-27 (2002).
-
(2002)
Am J Respir Cell Mol Biol
, vol.5
, pp. 619-627
-
-
Ramalho, A.S.1
Beck, S.2
Meyer, M.3
-
13
-
-
0036354946
-
Gene therapy for inherited lung disorders: An insight into pulmonary defence
-
Vadolas J, Williamson R, Ioannou PA. Gene therapy for inherited lung disorders: an insight into pulmonary defence. Pulmon Pharmacol Therapeut 15: 61-72 (2002).
-
(2002)
Pulmon Pharmacol Therapeut
, vol.15
, pp. 61-72
-
-
Vadolas, J.1
Williamson, R.2
Ioannou, P.A.3
-
14
-
-
4644359324
-
CFTR transgene expression in primary DeltaF508 epithelial cell cultures from human nasal polyps following gene transfer with cationic phosphonolipids
-
Montier T, Delépine P, Marianowski R, et al. CFTR transgene expression in primary DeltaF508 epithelial cell cultures from human nasal polyps following gene transfer with cationic phosphonolipids. Mol Biotechnol 26(3): 193-206 (2004).
-
(2004)
Mol Biotechnol
, vol.26
, Issue.3
, pp. 193-206
-
-
Montier, T.1
Delépine, P.2
Marianowski, R.3
-
15
-
-
34250222751
-
Genomic context vectors and artificial chromosomes for cystic fibrosis gene therapy
-
Conese M, Boyd AC, Di Gioia S, et al. Genomic context vectors and artificial chromosomes for cystic fibrosis gene therapy. Curr Gene Ther 7(3): 175-187 (2007).
-
(2007)
Curr Gene Ther
, vol.7
, Issue.3
, pp. 175-187
-
-
Conese, M.1
Boyd, A.C.2
Di Gioia, S.3
-
16
-
-
0347812926
-
The status of gene therapy for cystic fibrosis
-
Weiss DJ, Pilewski JM. The status of gene therapy for cystic fibrosis. Semin Respir Crit Care Med 24(6): 749-70 (2003).
-
(2003)
Semin Respir Crit Care Med
, vol.24
, Issue.6
, pp. 749-770
-
-
Weiss, D.J.1
Pilewski, J.M.2
-
17
-
-
33646191190
-
Gene therapy for cystic fibrosis airway disease- is clinical success imminent?
-
Anson DS, Smith GJ, Parsons DW. Gene therapy for cystic fibrosis airway disease- is clinical success imminent? Curr Gene Ther 6(2): 161-179 (2006).
-
(2006)
Curr Gene Ther
, vol.6
, Issue.2
, pp. 161-179
-
-
Anson, D.S.1
Smith, G.J.2
Parsons, D.W.3
-
18
-
-
26944472870
-
Physical and biological barriers to viral vector-mediated delivery of genes to the airway epithelium
-
Pickles RJ. Physical and biological barriers to viral vector-mediated delivery of genes to the airway epithelium. Proc Am Thorac Soc 1(4): 302-308 (2004).
-
(2004)
Proc Am Thorac Soc
, vol.1
, Issue.4
, pp. 302-308
-
-
Pickles, R.J.1
-
19
-
-
0028318416
-
Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats
-
Zabner J, Petersen DM, Puga AP, et al. Safety and efficacy of repetitive adenovirus-mediated transfer of CFTR cDNA to airway epithelia of primates and cotton rats. Nat Genet 6: 75-83 (1994).
-
(1994)
Nat Genet
, vol.6
, pp. 75-83
-
-
Zabner, J.1
Petersen, D.M.2
Puga, A.P.3
-
20
-
-
0025094612
-
Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer
-
Drumm ML, Pope HA, Cliff WH, et al. Correction of the cystic fibrosis defect in vitro by retrovirus-mediated gene transfer. Cell 62: 1227-1233 (1990).
-
(1990)
Cell
, vol.62
, pp. 1227-1233
-
-
Drumm, M.L.1
Pope, H.A.2
Cliff, W.H.3
-
21
-
-
0025155528
-
Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells
-
Rich DP, Anderson MP, Gregory RJ, et al. Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells. Nature 347: 358-363 (1990).
-
(1990)
Nature
, vol.347
, pp. 358-363
-
-
Rich, D.P.1
Anderson, M.P.2
Gregory, R.J.3
-
22
-
-
0027361622
-
Noninvasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice
-
Alton EW, Middleton PG, Caplen NJ, et al. Noninvasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice. Nat Genet 5: 135-142 (1993).
-
(1993)
Nat Genet
, vol.5
, pp. 135-142
-
-
Alton, E.W.1
Middleton, P.G.2
Caplen, N.J.3
-
23
-
-
0028913411
-
Liposomemediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
-
Caplen NJ, Alton EW, Middleton PG, et al. Liposomemediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1: 39-46 (1995).
-
(1995)
Nat Med
, vol.1
, pp. 39-46
-
-
Caplen, N.J.1
Alton, E.W.2
Middleton, P.G.3
-
24
-
-
0028245537
-
Cationic liposomes for direct gene transfer in therapy of cancer and other diseases
-
Farhood H, Gao X, Son K, et al. Cationic liposomes for direct gene transfer in therapy of cancer and other diseases. Ann N Y Acad Sci 716: 23-34 (1994).
-
(1994)
Ann N Y Acad Sci
, vol.716
, pp. 23-34
-
-
Farhood, H.1
Gao, X.2
Son, K.3
-
25
-
-
0033808419
-
Human coronavirus 229E infects polarized airway epithelia from the apical surface
-
Wang G, Deering C, Macke M, et al. Human coronavirus 229E infects polarized airway epithelia from the apical surface. J Virol 74(19): 9234-9239 (2000).
-
(2000)
J Virol
, vol.74
, Issue.19
, pp. 9234-9239
-
-
Wang, G.1
Deering, C.2
Macke, M.3
-
26
-
-
0036094947
-
Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology
-
Zhang L, Peeples ME, Boucher RC, et al. Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology. J Virol 76(11): 5654-66 (2002).
-
(2002)
J Virol
, vol.76
, Issue.11
, pp. 5654-5666
-
-
Zhang, L.1
Peeples, M.E.2
Boucher, R.C.3
-
27
-
-
33748860863
-
-
Kolb M, Martin G, Medina M, et al. Gene therapy for pulmonary diseases. Chest 130: 879-884 (2006).
-
Kolb M, Martin G, Medina M, et al. Gene therapy for pulmonary diseases. Chest 130: 879-884 (2006).
-
-
-
-
28
-
-
33748539369
-
Current prospects for gene therapy of cystic fibrosis
-
Ziady AG, Davis PB. Current prospects for gene therapy of cystic fibrosis. Curr Opin Pharmacol 6(5): 515-521 (2006).
-
(2006)
Curr Opin Pharmacol
, vol.6
, Issue.5
, pp. 515-521
-
-
Ziady, A.G.1
Davis, P.B.2
-
29
-
-
36749023425
-
Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function?
-
Lassance RM, Pássaro CP, Martini SV, et al. Does the use of recombinant AAV2 in pulmonary gene therapy damage lung function? Respir Physiol Neurobiol 160(1): 91-98 (2008).
-
(2008)
Respir Physiol Neurobiol
, vol.160
, Issue.1
, pp. 91-98
-
-
Lassance, R.M.1
Pássaro, C.P.2
Martini, S.V.3
-
31
-
-
0027484584
-
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector
-
Flotte TP, Afione SA, Conrad C, et al. Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proc Natl Acad Sci USA 90(22): 10613-10617 (1993).
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.22
, pp. 10613-10617
-
-
Flotte, T.P.1
Afione, S.A.2
Conrad, C.3
-
32
-
-
0026873533
-
Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer
-
Olsen JC, Johnson LG, Stutts MJ, et al. Correction of the apical membrane chloride permeability defect in polarized cystic fibrosis airway epithelia following retroviral-mediated gene transfer. Hum Gene Ther 3(3): 253-266 (1992).
-
(1992)
Hum Gene Ther
, vol.3
, Issue.3
, pp. 253-266
-
-
Olsen, J.C.1
Johnson, L.G.2
Stutts, M.J.3
-
33
-
-
10744227749
-
Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis trans-membrane regulator gene transfer to the lungs of patients with cystic fibrosis: A multicenter, double-blind, placebo-controlled trial
-
Moss RB, Rodman D, Spencer LT, et al. Repeated adeno-associated virus serotype 2 aerosol-mediated cystic fibrosis trans-membrane regulator gene transfer to the lungs of patients with cystic fibrosis: a multicenter, double-blind, placebo-controlled trial. Chest 125(2): 509-521 (2004).
-
(2004)
Chest
, vol.125
, Issue.2
, pp. 509-521
-
-
Moss, R.B.1
Rodman, D.2
Spencer, L.T.3
-
34
-
-
34548512049
-
Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: A randomized placebo-controlled phase 2B trial
-
Moss RB, Milla C, Colombo J, et al. Repeated aerosolized AAV-CFTR for treatment of cystic fibrosis: a randomized placebo-controlled phase 2B trial. Hum Gene Ther 18(8): 726-32 (2007).
-
(2007)
Hum Gene Ther
, vol.18
, Issue.8
, pp. 726-732
-
-
Moss, R.B.1
Milla, C.2
Colombo, J.3
-
35
-
-
0034992340
-
Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors
-
Halbert CL, Allen JM, Miller AD. Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors. J Virol 75(14): 6615-6624 (2001).
-
(2001)
J Virol
, vol.75
, Issue.14
, pp. 6615-6624
-
-
Halbert, C.L.1
Allen, J.M.2
Miller, A.D.3
-
36
-
-
17144401470
-
Novel molecular approaches to cystic fibrosis gene therapy
-
Lee TW, Matthews DA, Blair GE. Novel molecular approaches to cystic fibrosis gene therapy. Biochem J 387(Pt 1): 1-15 (2005).
-
(2005)
Biochem J
, vol.387
, Issue.PART 1
, pp. 1-15
-
-
Lee, T.W.1
Matthews, D.A.2
Blair, G.E.3
-
37
-
-
0029145960
-
Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and beta-galactosidase
-
van Ginkel FW, Liu C, Simecka JW, et al. Intratracheal gene delivery with adenoviral vector induces elevated systemic IgG and mucosal IgA antibodies to adenovirus and beta-galactosidase. Hum Gene Ther 6(7): 895-903 (1995).
-
(1995)
Hum Gene Ther
, vol.6
, Issue.7
, pp. 895-903
-
-
van Ginkel, F.W.1
Liu, C.2
Simecka, J.W.3
-
38
-
-
0031570890
-
Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene
-
van Ginkel FW, McGhee JR, Liu C, et al. Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene. J Immunol 159(2): 685-693 (1997).
-
(1997)
J Immunol
, vol.159
, Issue.2
, pp. 685-693
-
-
van Ginkel, F.W.1
McGhee, J.R.2
Liu, C.3
-
39
-
-
0035033758
-
Stealth adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung
-
Croyle MA, Chirmule N, Zhang Y, Wilson JM. "Stealth" adenoviruses blunt cell-mediated and humoral immune responses against the virus and allow for significant gene expression upon readministration in the lung. J Virol 75(10): 4792-4801 (2001).
-
(2001)
J Virol
, vol.75
, Issue.10
, pp. 4792-4801
-
-
Croyle, M.A.1
Chirmule, N.2
Zhang, Y.3
Wilson, J.M.4
-
40
-
-
0034756451
-
Expanding AAV packaging capacity with trans-splicing or overlapping vectors: A quantitative comparison
-
Duan D, Yue Y, Engelhardt JF. Expanding AAV packaging capacity with trans-splicing or overlapping vectors: a quantitative comparison. Mol Ther 4(4): 383-391 (2001).
-
(2001)
Mol Ther
, vol.4
, Issue.4
, pp. 383-391
-
-
Duan, D.1
Yue, Y.2
Engelhardt, J.F.3
-
41
-
-
27144509758
-
Current development of adeno-associated viral vectors
-
Romano G. Current development of adeno-associated viral vectors. Drug News Perspect 18(5): 311-316 (2005).
-
(2005)
Drug News Perspect
, vol.18
, Issue.5
, pp. 311-316
-
-
Romano, G.1
-
42
-
-
22544484533
-
Enhancing rAAV vector expression in the lung
-
Virella-Lowell I, Zusman B, Foust K, et al. Enhancing rAAV vector expression in the lung. J Gene Med 7(7): 842-50 (2005).
-
(2005)
J Gene Med
, vol.7
, Issue.7
, pp. 842-850
-
-
Virella-Lowell, I.1
Zusman, B.2
Foust, K.3
-
43
-
-
20044381100
-
A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia
-
Ostedgaard LS, Rokhlina T, Karp PH, et al. A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia. Proc Natl Acad Sci USA 102(8): 2952-2957 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.8
, pp. 2952-2957
-
-
Ostedgaard, L.S.1
Rokhlina, T.2
Karp, P.H.3
-
44
-
-
34548730279
-
Sendai virus-mediated CFTR gene transfer to the airway epithelium
-
Ferrari S, Griesenbach U, Iida A, et al. Sendai virus-mediated CFTR gene transfer to the airway epithelium. Gene Ther 14(19): 1371-1379 (2007).
-
(2007)
Gene Ther
, vol.14
, Issue.19
, pp. 1371-1379
-
-
Ferrari, S.1
Griesenbach, U.2
Iida, A.3
-
45
-
-
37149014804
-
Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector
-
Sinn PL, Goreham-Voss JD, Arias AC, et al. Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector. Hum Gene Ther 18(12): 1244-1252 (2007).
-
(2007)
Hum Gene Ther
, vol.18
, Issue.12
, pp. 1244-1252
-
-
Sinn, P.L.1
Goreham-Voss, J.D.2
Arias, A.C.3
-
46
-
-
34247876190
-
Vectors for airway gene delivery
-
Davis PB, Cooper MJ. Vectors for airway gene delivery. AAPS J 9(1): E11-E17 (2007).
-
(2007)
AAPS
, vol.J 9
, Issue.1
-
-
Davis, P.B.1
Cooper, M.J.2
-
47
-
-
0035885441
-
Human α-defensin-1 (HNP-1) inhibits adenoviral infection in vitro
-
Bastian A, Schaefer H. Human α-defensin-1 (HNP-1) inhibits adenoviral infection in vitro. Regulat Peptides 101: 157-161 (2001).
-
(2001)
Regulat Peptides
, vol.101
, pp. 157-161
-
-
Bastian, A.1
Schaefer, H.2
-
48
-
-
13144283616
-
An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene
-
Morsy MA, Gu M, Motzel S, et al. An adenoviral vector deleted for all viral coding sequences results in enhanced safety and extended expression of a leptin transgene. Proc Natl Acad Sci USA 95(14): 7866-7871 (1998).
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.14
, pp. 7866-7871
-
-
Morsy, M.A.1
Gu, M.2
Motzel, S.3
-
49
-
-
2542532276
-
Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation
-
Cormet-Boyaka E, Jablonsky M, Naren AP, et al. Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation. Proc Natl Acad Sci USA 101(21): 8221-8226 (2004).
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.21
, pp. 8221-8226
-
-
Cormet-Boyaka, E.1
Jablonsky, M.2
Naren, A.P.3
-
50
-
-
5644224818
-
Non-viral vectors in cystic fibrosis gene therapy: Progress and challenges
-
Montier T, Delépine P, Pichon C, et al. Non-viral vectors in cystic fibrosis gene therapy: progress and challenges. Trends Biotechnol 22(11):586-92 (2004).
-
(2004)
Trends Biotechnol
, vol.22
, Issue.11
, pp. 586-592
-
-
Montier, T.1
Delépine, P.2
Pichon, C.3
-
51
-
-
0036314791
-
Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction
-
Giangreco A, Reynolds SD, Stripp BR. Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction. Am J Pathol 161: 173-182 (2002).
-
(2002)
Am J Pathol
, vol.161
, pp. 173-182
-
-
Giangreco, A.1
Reynolds, S.D.2
Stripp, B.R.3
-
52
-
-
20444397431
-
Identification of bronchioalveolar stem cells in normal lung and lung cancer
-
Kim CF, Jackson EL, Woolfenden AE, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121: 823-835 (2005).
-
(2005)
Cell
, vol.121
, pp. 823-835
-
-
Kim, C.F.1
Jackson, E.L.2
Woolfenden, A.E.3
-
53
-
-
19944427214
-
Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: Potential therapy for cystic fibrosis
-
Wang G, Bunnell BA, Painter RG, et al. Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis. Proc Natl Acad Sci USA 102(1): 186-191 (2005).
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.1
, pp. 186-191
-
-
Wang, G.1
Bunnell, B.A.2
Painter, R.G.3
-
55
-
-
33746030309
-
Stem cells and cystic fibrosis
-
Conese M, Rejman J. Stem cells and cystic fibrosis. J Cystic Fibrosis 5: 141-143 (2006).
-
(2006)
J Cystic Fibrosis
, vol.5
, pp. 141-143
-
-
Conese, M.1
Rejman, J.2
-
56
-
-
34848821636
-
New pulmonary therapies for cystic fibrosis
-
Ratjen F. New pulmonary therapies for cystic fibrosis. Curr Opin Pulm Med 13(6): 541-546 (2007).
-
(2007)
Curr Opin Pulm Med
, vol.13
, Issue.6
, pp. 541-546
-
-
Ratjen, F.1
-
57
-
-
38949104082
-
How not to be seen: Immune-evasion strategies in gene therapy
-
Zaldumbide A, Hoeben RC. How not to be seen: immune-evasion strategies in gene therapy. Gene Ther 15(4): 239-246 (2008).
-
(2008)
Gene Ther
, vol.15
, Issue.4
, pp. 239-246
-
-
Zaldumbide, A.1
Hoeben, R.C.2
-
58
-
-
0006422025
-
The innate immune response of the respiratory epithelium
-
Diamond G, Legarda D, Ryan LK. The innate immune response of the respiratory epithelium. Immunol Rev 173: 27-38 (2000).
-
(2000)
Immunol Rev
, vol.173
, pp. 27-38
-
-
Diamond, G.1
Legarda, D.2
Ryan, L.K.3
-
59
-
-
0033067894
-
The toll-receptor family and control of innate immunity
-
Kopp EB, Medzhitov R. The toll-receptor family and control of innate immunity. Curr Opin Immunol 11: 13-18 (1999).
-
(1999)
Curr Opin Immunol
, vol.11
, pp. 13-18
-
-
Kopp, E.B.1
Medzhitov, R.2
-
60
-
-
46049120813
-
Toll-like receptors, transduction-effector pathways and disease diversity - evidence of an immunobiological paradigm explaining all human illness?
-
in press
-
Atkinson TJ. Toll-like receptors, transduction-effector pathways and disease diversity - evidence of an immunobiological paradigm explaining all human illness? Int Rev Immunol (2008) (in press).
-
(2008)
Int Rev Immunol
-
-
Atkinson, T.J.1
-
61
-
-
33846259390
-
Role of Ca2+ in responses of airway epithelia to Pseudomonas aeruginosa, flagellin, ATP, and thapsigargin
-
Fu Z, Bettega K, Carroll S, et al. Role of Ca2+ in responses of airway epithelia to Pseudomonas aeruginosa, flagellin, ATP, and thapsigargin. Am J Physiol Lung Cell Mol Physiol 292(1): L353-64 (2007).
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
, Issue.1
-
-
Fu, Z.1
Bettega, K.2
Carroll, S.3
-
62
-
-
2942544512
-
Toll-like receptors in normal and cystic fibrosis airway epithelial cells
-
Muir A, Soong G, Sokol S, et al. Toll-like receptors in normal and cystic fibrosis airway epithelial cells. Am J Respir Cell Mol Biol 30(6): 777-783 (2004).
-
(2004)
Am J Respir Cell Mol Biol
, vol.30
, Issue.6
, pp. 777-783
-
-
Muir, A.1
Soong, G.2
Sokol, S.3
-
63
-
-
33646237805
-
Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatoryresponse toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells
-
Shuto T, Furuta T, Oba M, et al. Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatoryresponse toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells. FASEB J 20(6): 782-784 (2006).
-
(2006)
FASEB J
, vol.20
, Issue.6
, pp. 782-784
-
-
Shuto, T.1
Furuta, T.2
Oba, M.3
-
64
-
-
12444322678
-
TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells
-
Greene CM, Carroll TP, Smith SG, et al. TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol 174(3): 1638-1646 (2005).
-
(2005)
J Immunol
, vol.174
, Issue.3
, pp. 1638-1646
-
-
Greene, C.M.1
Carroll, T.P.2
Smith, S.G.3
-
65
-
-
16344389339
-
Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis
-
Hauber HP, Tulic MK, Tsicopoulos A, et al. Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis. Can Respir J 12(1): 13-18 (2005).
-
(2005)
Can Respir J
, vol.12
, Issue.1
, pp. 13-18
-
-
Hauber, H.P.1
Tulic, M.K.2
Tsicopoulos, A.3
-
66
-
-
34347247718
-
Lentivirus vector-mediated gene transfer to the developing bronchiolar airway epithelium in the fetal lamb
-
Yu ZY, McKay K, van Asperen P, et al. Lentivirus vector-mediated gene transfer to the developing bronchiolar airway epithelium in the fetal lamb. J Gene Med 9(6):429-439 (2007).
-
(2007)
J Gene Med
, vol.9
, Issue.6
, pp. 429-439
-
-
Yu, Z.Y.1
McKay, K.2
van Asperen, P.3
-
67
-
-
33750010667
-
Gene therapy for cystic fibrosis lung disease: Current status and future perspectives
-
Rosenecker J, Huth S, Rudolph C. Gene therapy for cystic fibrosis lung disease: current status and future perspectives. Curr Opin Mol Ther 8(5): 439-445 (2006).
-
(2006)
Curr Opin Mol Ther
, vol.8
, Issue.5
, pp. 439-445
-
-
Rosenecker, J.1
Huth, S.2
Rudolph, C.3
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