Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector

Human Gene Therapy

Volumn 18, Issue 12, 2007, Pages 1244-1252

  Sinn, Patrick L ^a   Goreham Voss, Jessica D ^a   Arias, Ariadna C ^a   Hickey, Melissa A ^a   Maury, Wendy ^a   Chikkanna Gowda, C P ^a   McCray Jr , Paul B ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; GAG PROTEIN; LENTIVIRUS VECTOR; LUCIFERASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMICAL MODIFICATION; CODON; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG MECHANISM; FELINE IMMUNODEFICIENCY VIRUS; FEMALE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PROTEIN EXPRESSION; RETICULOENDOTHELIOSIS VIRUS; SPLEEN NECROSIS VIRUS U5; TRANSGENE;

ANIMALS; BACULOVIRIDAE; CODON, INITIATOR; FACTOR VIII; GENE EXPRESSION; GENE PRODUCTS, GAG; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; HEPATOCYTES; HUMANS; IMMUNODEFICIENCY VIRUS, FELINE; LENTIVIRUS; LUCIFERASES; MICE; MUTATION; RNA SPLICE SITES; TRAGER DUCK SPLEEN NECROSIS VIRUS; TRANSDUCTION, GENETIC;

AUTOGRAPHA CALIFORNICA; FELINE IMMUNODEFICIENCY VIRUS; LENTIVIRUS; MURINAE; SPLEEN NECROSIS VIRUS;

EID: 37149014804     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2006.127     Document Type: Article

References (29)

1. ARYA, S.K., ZAMANI, M., and KUNDRA, P. (1998). Human immunodeficiency virus type 2 lentivirus vectors for gene transfer: Expression and potential for helper virus-free packaging. Hum. Gene Ther. 9, 1371-1380.
2. DELENDA, C. (2004). Lentiviral vectors: Optimization of packaging, transduction and gene expression. J. Gene Med. 6(Suppl. 1), S125-S138.
3. FOLLENZI, A., AILLES, L.E., BAKOVIC, S., GEUNA, M., and NALDINI, L. (2000). Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat. Genet. 25, 217-222.
4. HARPER, S.Q., STABER, P.D., BECK, C.R., FINEBERG, S.K., STEIN, C., OCHOA, D., and DAVIDSON, B.L. (2006). Optimization of feline immunodeficiency virus vectors for RNA interference. J. Virol. 80, 9371-9380.
5. JOHNSTON, J.C., GASMI, M., LIM, L.E., ELDER, J.H., YEE, J.-K., JOLLY, D.J., CAMPBELL, K.P., DAVIDSON, B.L., and SAUTER, S.L. (1999). Minimum requirements for efficient transduction of dividing and nondividing cells by feline immunodeficiency virus vectors. J. Virol. 73, 4991-5000.
6. KANG, Y., STEIN, C.S., HETH, J.A., SINN, P.L., PENISTEN, A.K., STABER, P.D., RATLIFF, K.L., SHEN, H., BARKER, C.K., MARTINS, I., SHARKEY, C.M., SANDERS, D.A., MCCRAY, P.B., Jr., and DAVIDSON, B.L. (2002). In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River virus glycoproteins. J. Virol. 76, 9378-9388.
7. KANG, Y., XIA, L., TRAN, D.T., STEIN, C.S., HICKEY, M., DAVIDSON, B.L., and MCCRAY, P.B., Jr. (2005). Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood 106, 1552-1558.
8. KANG, Y., MORESSI, C.J., SCHEETZ, T.E., XIE, L., TRAN, D.T., CASAVANT, T.L., AK, P., BENHAM, C.J., DAVIDSON, B.L., and MCCRAY, P.B., Jr. (2006). Integration site choice of a feline immunodeficiency virus vector. J. Virol. 80, 8820-8823.
9. KEMLER, I., BARRAZA, R., and POESCHLA, E.M. (2002). Mapping the encapsidation determinants of feline immunodeficiency virus. J. Virol. 76, 11889-11903.
10. KEMLER, I., AZMI, I., and POESCHLA, E.M. (2004). The critical role of proximal gag sequences in feline immunodeficiency virus genome encapsidation. Virology 327, 111-120.
11. KLIMATCHEVA, E., ROSENBLATT, J.D., and PLANELLES, V. (1999). Lentiviral vectors and gene therapy. Front. Biosci. 4, D481-D496.
12. LOGAN, A.C., NIGHTINGALE, S.J., HAAS, D.L., CHO, G.J., PEPPER, K.A., and KOHN, D.B. (2004). Factors influencing the titer and infectivity of lentiviral vectors. Hum. Gene Ther. 15, 976-988.
13. MIAO, H.Z., SIRACHAINAN, N., PALMER, L., KUCAB, P., CUNNINGHAM, M.A., KAUFMAN, R.J., and PIPE, S.W. (2004). Bioengineering of coagulation factor VIII for improved secretion. Blood 103, 3412-3419.
14. MIYAZAWA, T., KAWAGUCHI, Y., KOHMOTO, M., TOMONAGA, K., and MIKAMI, T. (1994). Comparative functional analysis of the various lentivirus long terminal repeats in human colon carcinoma cell line (SW480 cells) and feline renal cell line (CRFK cells). J. Vet. Med. Sci. 56, 895-899.
15. O'ROURKE, J.P., NEWBOUND, G.C., KOHN, D.B., OLSEN, J.C., and BUNNELL, B.A. (2002). Comparison of gene transfer efficiencies and gene expression levels achieved with equine infectious anemia virus- and human immunodeficiency virus type 1-derived lentivirus vectors. J. Virol. 76, 1510-1515.
16. REED-INDERBITZIN, E., and MAURY, W. (2003). Cellular specificity of HIV-1 replication can be controlled by LTR sequences. Virology 314, 680-695.
17. ROBERTS, T.M., and BORIS-LAWRIE, K. (2003). Primary sequence and secondary structure motifs in spleen necrosis virus RU5 confer translational utilization of unspliced human immunodeficiency virus type 1 reporter RNA. J. Virol. 77, 11973-11984.
18. SASTRY, L., XU, Y., COOPER, R., POLLOK, K., and CORNETTA, K. (2004). Evaluation of plasmid DNA removal from lentiviral vectors by Benzonase treatment. Hum. Gene Ther. 15, 221-226.
19. SHERIDAN, P.L., BODNER, M., LYNN, A., PHUONG, T.K., DEPOLO, N.J., DE LA VEGA, D.J., Jr., O'DEA, J., NGUYEN, K., MCCORMACK, J.E., DRIVER, D.A., TOWNSEND, K., IBANEZ, C.E., SAJJADI, N.C., GREENGARD, J.S., MOORE, M.D., RESPESS, J., CHANG, S.M., DUBENSKY, T.W., Jr., JOLLY, D.J., and SAUTER, S.L. (2000). Generation of retroviral packaging and producer cell lines for large-scale vector production and clinical application: Improved safety and high titer. Mol. Ther. 2, 262-275.
20. SINN, P.L., and SIGMUND, C.D. (1999). Human renin mRNA stability is increased in response to cAMP in Calu-6 cells. Hypertension 33, 900-905.
21. SINN, P.L., HICKEY, M.A., STABER, P.D., DYLLA, D.E., JEFFERS, S.A., DAVIDSON, B.L., SANDERS, D.A., and MCCRAY, P.B., Jr. (2003). Lentivirus pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independent of folate receptor-α. J. Virol. 77, 5902-5910.
22. SINN, P.L., BURNIGHT, E.R., HICKEY, M.A., BLISSARD, G.W., and MCCRAY, P.B., Jr. (2005a). Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer. J. Virol. 79, 12818-12827.
23. SINN, P.L., SHAH, A., DONOVAN, M., and MCCRAY, P.B., Jr. (2005b). Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors. Am. J. Respir. Cell Mol. Biol. 32, 404-410.
24. SMITH, R.A., REMINGTON, K.M., PRESTON, B.D., SCHINAZI, R.F., and NORTH, T.W. (1998). A novel point mutation at position 156 of reverse transcriptase from feline immunodeficiency virus confers resistance to the combination of (-)-β-2′,3′-dideoxy-3′-thiacytidine and 3′-azido-3′-deoxythymidine. J. Virol. 72, 2335-2340.
25. WHITWAM, T., PERETZ, M., and POESCHLA, E. (2001). Identification of a central DNA flap in feline immunodeficiency virus. J. Virol. 75, 9407-9414.
26. YILMAZ, A., FERNANDEZ, S., LAIRMORE, M.D., and BORIS-LAWRIE, K. (2006). Coordinate enhancement of transgene transcription and translation in a lentiviral vector. Retrovirology 3, 13.
27. ZENNOU, V., PETIT, C., GUETARD, D., NERHBASS, U., MONTAGNIER, L., and CHARNEAU, P. (2000). HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 101, 173-185.
28. ZUFFEREY, R., DULL, T., MANDEL, R.J., BUKOVSKY, A., QUIROZ, D., NALDINI, L., and TRONO, D. (1998). Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J. Virol. 72, 9873-9880.
29. ZUFFEREY, R., DONELLO, J.E., TRONO, D., and HOPE, T.J. (1999). Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol. 73, 2886-2892.