Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic β cell function

Kobe Journal of Medical Sciences

Volumn 54, Issue 2, 2008, Pages

  Matsuda, Tomokazu ^a   Kido, Yoshiaki ^a   Uchida, Tohru ^a   Kasuga, Masato ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Db db mice; Endoplasmic reticulum stress; Insulin signaling; Pancreatic cell failure; Type 2 diabetes

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ELONGATION FACTOR 2; INSULIN; LEPTIN RECEPTOR; PROTEIN C JUN; PROTEIN KINASE B; TUNICAMYCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CELL FUNCTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IN VITRO STUDY; INSULIN BLOOD LEVEL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INSULINOMA; MICE; MICE, KNOCKOUT; RECEPTORS, LEPTIN;

EID: 47849099867     PISSN: 00232513     EISSN: 18830498     Source Type: Journal    
DOI: None     Document Type: Article

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