Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: Pathogenesis of diabetes in a mouse model

Diabetologia

Volumn 42, Issue 4, 1999, Pages 427-434

  Hoppener J W M ^a,c   Oosterwijk, C ^a   Nieuwenhuis, M G ^a   Posthuma, G ^a   Thijssen, J H H ^a   Vroom, Th M ^a   Ahren B ^b   Lips, C J M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b LUND UNIVERSITY   (Sweden)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Amylin; Diabetogenic factor; IAPP; Insulin insufficiency; Insulin resistance; Islet amyloid; Ob ob mice; Transgenic mice

Indexed keywords

AMYLIN; AMYLOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; IMMUNOHISTOCHEMISTRY; INSULIN DEFICIENCY; INSULIN RELEASE; INSULIN RESISTANCE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AMYLOID; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, OBESE; MICE, TRANSGENIC; POINT MUTATION;

EID: 0141780910     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051175     Document Type: Article

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