Aggregation of liposomes induced by the toxic peptides Alzheimer's Aβs, human amylin and prion (106-126): Facilitation by membrane-bound GM1 ganglioside

Peptides

Volumn 25, Issue 2, 2004, Pages 217-232

  Kurganov, Boris ^a   Doh, Michael ^b   Arispe, Nelson ^b  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

Author keywords

A ; Amylin; Beta amyloid; Liposome aggregation; Membrane interaction; Phosphatidylserine; Prion; Toxic peptides

Indexed keywords

AMYLIN; AMYLOID BETA PROTEIN[1-42]; GANGLIOSIDE GM1; LIPOSOME; PHOSPHOLIPID; PRION PROTEIN[106-126]; TOXIC SUBSTANCE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; COMPLEX FORMATION; CONCENTRATION RESPONSE; KINETICS; LIPID MEMBRANE; MEMBRANE BINDING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; OPTICAL DENSITY; PHASE SEPARATION; PRION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; REDUCTION KINETICS;

AMYLOID; AMYLOID BETA-PROTEIN; ANIMALS; G(M1) GANGLIOSIDE; HUMANS; LIPIDS; LIPOSOMES; PHOSPHATIDYLSERINES; PRIONS;

EID: 1942420641     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2004.01.001     Document Type: Article

References (59)

1. Ariga T., Kobayashi K., Hasegawa A., Kiso M., Miyatake T. Characterization of high-affinity binding between gangliosides and amyloid beta-protein. Arch. Biochem. Biophys. 388(2):2001;225-230.
2. Arispe N., Doh M. Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AβP(1-40) and (1-42) peptides. FASEB J. 16:2002;1526-1536.
3. Arispe N., Doh M., De Maio A. Lipid interactions differentiates the constitutive and stress-induced heat shock proteins Hsc70 and Hsp70. Cell Stress Chaperones. 7(4):2002;330-338.
4. Arispe N., Rojas E., Pollard H.B. Alzheimer disease amyloid β-protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. Proc. Natl. Acad. Sci. U.S.A. 90:1993;567-571.
5. Arispe N., Rojas E., Pollard H.B. Giant multilevel cation channels formed by Alzheimer disease amyloid β-protein [AβP-(1-40)] in bilayer membranes. Proc. Natl. Acad. Sci. U.S.A. 90:1993;10573-10577.
6. Barrow C.J., Yasuda A., Kenny P.T.M., Zagorski M.G. Solution conformations and aggregational properties of synthetic amyloid β-peptides of Alzheimer's disease. Analysis of circular dichroism spectra. J. Mol. Biol. 225:1992;1075-1093.
7. Bhathia R., Lin H., Lal R. Fresh and globular amyloid β protein induces rapid cellular degeneration. A possible implication for calcium-uptake via AβP-channel. FASEB J. 14(9):2000;1233-1243.
8. Blackwood R.A., Ernst J.D. Characterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins. Biochem. J. 266(1):1990;195-200.
9. Burdick D., Soreghan B., Kwon M., Kosmoski J., Knauer M., Henschen A.et al. Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs. J. Biol. Chem. 267:1992;546-554.
10. 2+/GTP sensor in exocytotic secretion. Proc. Natl. Acad. Sci. U.S.A. 93:1996;10797-10802.
11. Choo-Smith L.P., Garzon-Rodriguez W., Glabe C.G., Surewicz W.K. Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles. J. Biol. Chem. 272(37):1997;22987-22990.
12. M1-containing membranes. FEBS Lett. 402:1997;95-98.
13. De Gioia L., Selvaggini C., Ghibaudi E., Diomede L., Bugiani O., Forlini G.et al. Conformational polymorphism of the amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein. J. Biol. Chem. 269:1994;7859-7862.
14. de la Fuente M., Parra A.V. Vesicle aggregation by annexin I: role of a secondary membrane binding site. Biochemistry. 34(33):1995;10393-10399.
15. Dore S., Kar S., Quirion R. Insulin-like growth factor I protects and rescues hippocampal neurons against β-amyloid- and human amylin-induced toxicity. Proc. Natl. Acad. Sci. U.S.A. 94:1997;4772-4777.
16. Durrell S.R., Guy H.R., Arispe N., Rojas E., Pollard H.B. Theoretical models of the ion channel structure of amyloid-β-protein. Biophys. J. 67:1994;2137-2145.
17. Felgner P.L., Freire E., Barenholz Y., Thompson T.E. Asymmetric incorporation of trisialoganglioside into dipalmitoylphosphatidylcholine vesicles. Biochemistry. 20(8):1981;2168-2172.
18. Ghanta J., Shen C.-L., Kiessling L.L., Murphy R.M. A strategy for designing inhibitors of β-amyloid toxicity. J. Biol. Chem. 271(47):1996;29525-29528.
19. 2+-regulated phospholipid- and actin-binding proteins isolated from lung and placenta. J. Cell Biol. 104(3):1987;503-511.
20. Goldsbury C.S., Cooper G.J., Goldie K.N., Muller S.A., Saafi E.L., Gruijters W.T.et al. Polymorphic fibrillar assembly of human amylin. J. Struct. Biol. 119(1):1997;17-27.
21. Goldsbury C., Goldie K., Pellaud J., Seelig J., Frey P., Muller S.A.et al. Amyloid fibril formation from full-length and fragments of amylin. J. Struct. Biol. 130(2/3):2000;352-362.
22. Goldsbury C., Kistler J., Aebi U., Arvinte T., Cooper G.J. Watching amyloid fibrils grow by time-lapse atomic force microscopy. J. Mol. Biol. 285:1999;33-39.
23. Hartley D.M., Walsh D.M., Ye C.P., Diehl T., Vasquez S., Vassilev P.M.et al. Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19(20):1999;8876-8884.
24. Hong K., Duzgunes N., Papahadjopoulos D. Role of synexin in membrane fusion. Enhancement of calcium-dependent fusion of phospholipid vesicles. J. Biol. Chem. 256:1981;3641-3644.
25. Janson J., Soeller W.C., Roche P.C., Nelson R.T., Torchia A.J., Kreutter D.K.et al. Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide. Proc. Natl Acad. Sci. U.S.A. 93:1996;7283-7288.
26. Kakio A., Nishimoto S., Yanagisawa K., Kozutsumi Y., Matsuzaki K. Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid. J. Biol. Chem. 276:2001;24985-24990.
27. Kakio A., Nishimoto S., Yanagisawa K., Kozutsumi Y., Matsuzaki K. Interactions of amyloid β-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid. Biochemistry. 41:2002;7385-7390.
28. Kakio A., Nishimoto S., Kozutsumi Y., Matsuzaki K. Formation of a membrane-active form of amyloid β-protein in raft-like model membranes. Biochem. Biophys. Res. Commun. 301:2003;514-518.
29. 2+-sensitive cation-selective channels across excited membrane patches from hypothalamic neurons. Biophys. J. 73:1997;67-75.
30. Kawahara M., Arispe N., Kuroda Y., Rojas E. Alzheimer's β-amyloid, human amylin and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line. J. Biol. Chem. 275:2000;14077-14083.
31. Kourie J.I., Culverson A. Prion peptide fragment PrP[106-126] forms distinct cation channel types. J. Neurosci. Res. 62(1):2000;120-133.
32. Kourie J.I., Shorthouse A.A. Properties of cytotoxic peptide-formed ion channels. Am. J. Physiol. Cell Physiol. 278(6):2000;C1063-C1087.
33. Kourie J.I., Farrelly P.V., Henry C.L. Channel activity of deamidated isoforms of prion protein fragment 106-126 in planar lipid bilayers. J. Neurosci. Res. 66(2):2001;214-220.
34. Kurganov B.I., Rafikova E.R., Dobrov E.N. Kinetics of thermal aggregation of tobacco mosaic virus coat protein. Biochemistry (Mosc.). 67(5):2002;525-533.
35. Lee G., Pollard H.B. Highly sensitive and stable phosphatidylserine liposome aggregation assay for annexins. Anal. Biochem. 252:1997;160-164.
36. Lee G., Pollard H.B., Arispe N. Annexin 5 and apolipoprotein E2 protect against Alzheimer's amyloid β peptide cytotoxicity by competitive inhibition at a common phosphatidylserine interaction site. Peptides. 23:2002;1249-1263.
37. 2+ sensitive channels in reconstituted lipid vesicles. Biochemistry. 38:1999;11189-11196.
38. Lorenzo A., Razzaboni B., Weir G.C., Yankner B.A. Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus. Nature. 368:1994;756-760.
39. May P.C., Boggs L.N., Fuson K.S. Neurotoxicity of human amylin in rat primary hippocampal cultures: similarity to Alzheimer's disease amyloid-β neurotoxicity. J. Neurochem. 61:1993;2330-2333.
40. Mirzabekov T.A., Lin M.-C., Kagan B.L. Pore formation by the cytotoxic islet amyloid peptide amylin. J. Biol. Chem. 271:1996;1988-1992.
41. Pike C.J., Overman M.J., Cotman C.W. Amino-terminal deletions enhance aggregation of amyloid peptides in vitro. J. Biol. Chem. 270(41):1995;23895- 23898.
42. Pike C.J., Walencewicz A.J., Glabe C.G., Cottman C.W. In vitro aging of β-amyloid protein causes peptide aggregation and neurotoxicity. Brain Res. 563:1991;311-314.
43. Prusiner S.B., Scott M.R., DeArmond S.J., Cohen F.E. Prion protein biology. Cell. 93:1998;337-348.
44. Roher A.E., Ball M.J., Bhave S.V., Wakade A.R. β-Amyloid from Alzheimer disease brains inhibits sprouting and survival of sympathetic neurons. Biochem. Biophys. Res. Commun. 174:1991;572-579.
45. Rumora L., Hadzija M., Barisic K., Maysinger D., Grubiic T.Z. Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases. Biol. Chem. 383(11):2002;1751-1758.
46. Saafi E.L., Konarkowska B., Zhang S., Kistler J., Cooper G.J.S. Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet β-cells. Cell Biol. Int. 25:2001;339-350.
47. Schubert D., Behl C., Lesley R., Brack A., Dargusch R., Sagara Y.et al. Amyloid peptides are toxic via a common oxidative mechanism. Proc. Natl. Acad. Sci. U.S.A. 92:1995;1989-1993.
48. Schwingshackl A., Blasko I., Steiner E., Pozzilli P., Cavallo M.G., Berger P.et al. Sex steroids do not prevent amylin-induced apoptosis in human cells. Exp. Cell Res. 241:1998;265-268.
49. Simmons L.K., May P.C., Tomaselli K.J., Rydel R.E., Fuson K.S., Brigham E.F.et al. Secondary structure of β-amyloid peptide correlates with toxicity in vitro. Soc. Neurosci. Abstr. 19:1993;397.
50. Soeller W.C., Janson J., Hart S.E., Parker J.C., Carty M.D., Stevenson R.W.et al. Islet amyloid-associated diabetes in obese a(vy)/a mice expressing human islet amyloid polypeptide. Diabetes. 47:1998;743-750.
51. Soto C., Kindy M.S., Baumann M., Frangione B. Inhibition of Alzheimer's amyloidosis by peptides that prevent β-sheet conformation. Biochem. Biophys. Res. Commun. 226:1996;672-680.
52. Stege G.J.J., Renkawek P.S.G., Overkamp P., Verschuure A.F., van Rijk A., Reijnen-Aalberts W.C.et al. The molecular chaperone αB-crystallin enhances amyloid β neurotoxicity. Biochem. Biophys. Res. Commun. 262:1999;152-156.
53. Terzi E., Holzemann G., Seelig J. Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes. J. Mol. Biol. 252(5):1995;633-642.
54. Tjernberg L.O., Näslund J., Lindqvist F., Johansson J., Karlström A.R., Thyberg J.et al. Arrest of β-amyloid fibril formation by a pentapeptide ligand. J. Biol. Chem. 271(15):1996;8545-8548.
55. Wang K., Kurganov B.I. Kinetics of heat- and acidification-induced aggregation of firefly luciferase. Biophys. Chem. 106(2):2003;97-109.
56. Yankner B.A., Duffy L.K., Kirschner D.A. Neurotrophic and neurotoxic effects of amyloid β protein: reversal by tachykinin neuropeptides. Science. 250:1990;279-282.
57. WAF1/CIP1. FEBS Lett. 455:1999;315-320.
58. Zhang S., Liu J., MacGibbon G., Dragunow M., Cooper G.J. Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J. Mol. Biol. 324(2):2002;271-285.
59. Zhu Y.J., Lin H., Lal R. Fresh and nonfibrillar amyloid β protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AβP-channel-mediated cellular toxicity. FASEB J. 14(9):2000;1244-1254.