Homo- and Heterooligomeric SNARE Complexes Studied by Site-directed Spin Labeling

Journal of Biological Chemistry

Volumn 276, Issue 16, 2001, Pages 13169-13177

  Margittai, Martin ^a   Fasshauer, Dirk ^a   Pabst, Stefan ^a   Jahn, Reinhard ^a   Langen, Ralf ^b  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; COMPLEXATION; CONFORMATIONS; CRYSTAL STRUCTURE; NEUROLOGY;

HETEROOLIGOMERIC COMPLEXES;

PROTEINS;

OLIGOMER; SNARE PROTEIN; SYNAPTOBREVIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; SYNTAXIN; SYNTAXIN 1; UNCLASSIFIED DRUG; CYSTEINE; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; NERVE PROTEIN; PEPTIDE FRAGMENT; VESICULAR TRANSPORT PROTEIN;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; MEMBRANE FUSION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SPECTROSCOPY; SPIN LABELING; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ELECTRON SPIN RESONANCE; GENE DELETION; MACROMOLECULE; METABOLISM; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

HOMO;

AMINO ACID SUBSTITUTION; ANTIGENS, SURFACE; BINDING SITES; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; MACROMOLECULAR SUBSTANCES; MEMBRANE FUSION; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; NERVE TISSUE PROTEINS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; R-SNARE PROTEINS; SEQUENCE DELETION; SNARE PROTEINS; SPIN LABELS; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25; SYNTAXIN 1; VESICULAR TRANSPORT PROTEINS;

EID: 0035918302     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010653200     Document Type: Article

References (48)

1. Rothman, J. E. (1994) Nature 372, 55-63
2. Jahn, R., and Südhof, T. C. (1999) Annu. Rev. Biochem. 68, 863-911
3. Hughson, F. M. (1999) Curr. Biol. 9, R49-R52
4. Brünger, A. T. (2000) Curr. Opin. Neurobiol. 10, 293-302
5. Lin, R. C., and Scheller, R. H. (2000) Annu. Rev. Cell Dev. Biol. 16, 19-49
6. Söllner, T., Whiteheart, S. W., Brunner, M., Erdjument-Bromage, H., Geromanos, S., Tempst, P., and Rothman, J. E. (1993) Nature 362, 318-324
7. Söllner, T., Bennett, M. K., Whiteheart, S. W., Scheller, R. H., and Rothman, J. E. (1993) Cell 75, 409-418
8. Hanson, P. I., Heuser, J. E., and Jahn, R. (1997) Curr. Opin. Neurobiol. 7, 310-315
9. Terrian, D. M., and White, M. K. (1997) Eur J. Cell Biol. 73, 198-204
10. Weimbs, T., Low, S. H., Chapin, S. J., Mostov, K. E., Bucher, P., and Hofmann, K. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3046-3051
11. Weimbs, T., Mostov, K., Low, S. H., and Hofmann, K. (1998) Trends Cell Biol. 8, 260-262
12. Hayashi, T., McMahon, H., Yamasaki, S., Binz, T., Hata, Y., Südhof, T. C., and Niemann, H. (1994) EMBO J. 13, 5051-5061
13. Pevsner, J., Hsu, S. C., Braun, J. E., Calakos, N., Ting, A. E., Bennett, M. K., and Scheller, R. H. (1994) Neuron 13, 353-361
14. Hayashi, T., Yamasaki, S., Nauenburg, S., Binz, T., and Niemann, H. (1995) EMBO J. 14, 2317-2325
15. Calakos, N., Bennett, M. K., Peterson, K. E., and Scheller, R. H. (1994) Science 263, 1146-1149
16. Kee, Y., Lin, R. C., Hsu, S. C., and Scheller, R. H. (1995) Neuron 14, 991-998
17. Chapman, E. R., An, S., Barton, N., and Jahn, R. (1994) J. Biol. Chem. 269, 27427-27432
18. Zhong, P., Chen, Y. A., Tam, D., Chung, D., Scheller, R. H., and Miljanich, G. P. (1997) Biochemistry 36, 4317-4326
19. Poirier, M. A., Hao, J. C., Malkus, P. N., Chan, C., Moore, M. F., King, D. S., and Bennett, M. K. (1998) J. Biol. Chem. 273, 11370-11377
20. Hao, J. C., Salem, N., Peng, X. R., Kelly, R. B., and Bennett, M. K. (1997) J. Neurosci. 17, 1596-1603
21. Fasshauer, D., Eliason, W. K., Brünger, A. T., and Jahn, R. (1998) Biochemistry 37, 10354-10362
22. Sutton, R. B., Fasshauer, D., Jahn, R., and Brünger, A. T. (1998) Nature 395, 347-353
23. Fasshauer, D., Sutton, R. B., Brünger, A. T., and Jahn, R. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15781-15786
24. Fernandez, I., Ubach, J., Dulubova, I., Zhang, X., Südhof, T. C., and Rizo, J. (1998) Cell 94, 841-849
25. Lerman, J. C., Robblee, J., Fairman, R., and Hughson, F. M. (2000) Biochemistry 39, 8470-8479
26. Misura, K. M., Scheller, R. H., and Weis, W. I. (2000) Nature 404, 355-362
27. Hanson, P. I., Otto, H., Barton, N., and Jahn, R. (1995) J. Biol. Chem. 270, 16955-16961
28. Dulubova, I., Sugita, S., Hill, S., Hosaka, M., Fernandez, I., Südhof T. C., and Rizo, J. (1999) EMBO J. 18, 4372-4382
29. Fasshauer, D., Otto, H., Eliason, W. K., Jahn, R., and Brünger, A. T. (1997) J. Biol. Chem. 272, 28036-28041
30. Fasshauer, D., Bruns, D., Shen, B., Jahn, R., and Brünger, A. T. (1997) J. Biol. Chem. 272, 4582-4590
31. Hazzard, J., Südhof, T. C., and Rizo, J. (1999) J. Biomol. NMR 14, 203-207
32. Hanson, M. A., and Stevens, R. C. (2000) Nat. Struct. Biol. 7, 687-692
33. Xu, T., Rammner, B., Margittai, M., Artalejo, A. R., Neher, E., and Jahn, R. (1999) Cell 99, 713-722
34. Hubbell, W. L., Cafiso, D. S., and Altenbach, C. (2000) Nat. Struct. Biol. 7, 735-739
35. Hubbell, W. L., McHaourab, H. S., Altenbach, C., and Lietzow, M. A. (1996) Structure 4, 779-783
36. Hubbell, W. L., Gross, A., Langen, R., and Lietzow, M. A. (1998) Curr. Opin. Struct. Biol. 8, 649-656
37. Feix, J. B., and Klug, C. S. (1998) in Biological Magnetic Resonance Vol. 14, Spin Labeling: The Next Millenium (Berliner, L. J., ed) pp. 251-281, Plenum Press, New York
38. McHaourab, H. S., Lietzow, M. A., Hideg, K., and Hubbell, W. L. (1996) Biochemistry 35, 7692-7704
39. Langen, R., Oh, K. J., Cascio, D., and Hubbell, W. L. (2000) Biochemistry 39, 8396-8405
40. Rabenstein, M. D., and Shin, Y. K. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8239-8243
41. Farrens, D. L., Altenbach, C., Yang, K., Hubbell, W. L., and Khorana, H. G. (1996) Science 274, 768-770
42. Poirier, M. A., Xiao, W., Macosko, J. C., Chan, C., Shin, Y. K., and Bennett, M. K. (1998) Nat. Struct. Biol. 5, 765-769
43. Fasshauer, D., Antonin, W., Margittai, M., Pabst, S., and Jahn, R. (1999) J. Biol. Chem. 274, 15440-15446
44. Higuchi, R. (1990) in PCR Protocols: A Guide to Methods and Applications (Innis, M. A., Gelfand, D. H., Sinisky, J. J., and White, T. J., eds) pp. 177-183, Academic Press, New York
45. Rice, L. M., Brennwald, P., and Brünger, A. T. (1997) FEBS Lett. 415, 49-55
46. Nicholson, K. L., Munson, M., Miller, R. B., Filip, T. J., Fairman, R., and Hughson, F. M. (1998) Nat. Struct. Biol. 5, 793-802
47. Antonin, W., Holroyd, C., Fasshauer, D., Pabst, S., Fischer von Mollard, G., and Jahn, R. (2000) EMBO J. 19, 6453-6464
48. Fiebig, K. M., Rice, L. M., Pollock, E., and Brünger, A. T. (1999) Nat. Struct. Biol. 6, 117-123