Structural changes of the prion protein in lipid membranes leading to aggregation and fibrillization

Biochemistry

Volumn 42, Issue 11, 2003, Pages 3295-3304

  Kazlauskaite, Jurate ^a   Sanghera, Narinder ^a,c,d   Sylvester, Ian ^a,c,d   Vénien Bryan, Catherine ^b   Pinheiro, Teresa J T ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Accentus plc   (United Kingdom)

^d INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMORPHOUS MATERIALS; BIOLOGICAL MEMBRANES; CHOLESTEROL; LIPIDS;

PRION PROTEIN;

PROTEINS;

CHOLESTEROL; CHOLINE DERIVATIVE; DIPALMITOYLPHOSPHATIDYLCHOLINE; OLEOYLPALMITOYLLECITHIN; PRION PROTEIN; PROTEIN SUBUNIT; SPHINGOMYELIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CHEMICAL COMPOSITION; LIPID BILAYER; LIPID MEMBRANE; MEMBRANE BINDING; MEMBRANE MODEL; MEMBRANE VESICLE; MOLECULAR STABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE;

ANIMALS; CRICETINAE; MEMBRANE LIPIDS; MESOCRICETUS; MICROSCOPY, ELECTRON; PROTEIN CONFORMATION; PROTEIN FOLDING; PRPC PROTEINS; RECOMBINANT PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 0037465821     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026872q     Document Type: Article

References (53)

1. Prusiner, S. B. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 13363-13383.
2. Caughey, B. W., Dong, A., Bhat, K. S., Ernst, D., Hayes, S. F., and Caughey, W. S. (1991) Biochemistry 30, 7672-7680.
3. Pan, K. M., Baldwin, M. A., Nguyen, J., Gasset, M., Servban, A., Groth, D., Mehlhorn, I., Huang, Z., Fletterick, R. J., Cohen, F. E., and Prusiner, S. B. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 10962-10966.
4. Caughey, B., Raymond, G. J., Callahan, M. A., Wong, C., Baron, G. S., and Xiong, L.-W. (2001) Adv. Protein Chem. 57, 139-169.
5. Zhang, H., Stöckel, J., Mehlhorn, I., Groth, D., Baldwin, M. A., Prusiner, S. B., James, T. L., and Cohen, F. E. (1997) Biochemistry 36, 3543-3553.
6. Lu, B.-Y., and Chang, J.-Y. (2001) Biochemistry 40, 13390-13396.
7. Swietnicki, W., Morillas, M., Chen, S. G., Gambetti, P., and Surewicz, W. K. (2000) Biochemistry 39, 424-431.
8. Baskakov, I. V., Legname, G., Baldwin, M. A., Prusiner, S. B., and Cohen, F. E. (2002) J. Biol. Chem. 277, 21140-21148.
9. Jackson, G. S., Hosszu, L. L. P., Power, A., Hill, A. F., Kenney, J., Saibil, H., Craven, C. J., Waltho, J. P., Clarke, A. R., and Collinge, J. (1999) Science 283, 1935-1937.
10. Morillas, M., Vanik, D. L., and Surewicz, W. K. (2001) Biochemistry 40, 6982-6987.
11. Jansen K., Schafer, O., Birkmann, E., Post, K., Serban, H., Prusiner, S. B., and Riesner, D. (2001) Biol. Chem. 382, 683-691.
12. Gabizon, R., McKinley, M. P., and Prusiner, S. B. (1987) Proc. Natl. Acad. Sci. U.S.A. 84, 4017-4021.
13. Stahl, N., Borchelt, D. R., and Prusiner, S. B. (1990) Biochemistry 29, 5405-5412.
14. Safar, J., Ceroni, M., Gajdusek, D. C., and Gibbs, C. J. (1991) J. Infect. Dis. 163, 488-494.
15. Lehmann, S., and Harris, D. A. (1995) J. Biol. Chem. 270, 24589-24597.
16. Hay, B., Prusiner, S. B., and Lingappa, V. R. (1987) Biochemistry 26, 8110-8115.
17. Stahl, N., Borchelt, D. R., Hsiao, K., and Prusiner, S. B. (1987) Cell 51, 229-240.
18. Vey, M., Pilkuhn, S., Wille, H., Nixon, R., DeArmond, S. J., Smart, E. J., Anderson, R. G. W., Taraboulos, A., and Prusiner, S. B. (1996) Proc. Natl.ny Acad. Sci. U.S.A. 93, 14945-14949.
19. Naslavsky, N., Stein, R., Yanai, A., Friedlander, G., and Taraboulos, A. (1997) J. Biol. Chem. 272, 6324-6331.
20. Caughey, B., and Raymond, G. J. (1991) J. Biol. Chem. 266, 18217-18224.
21. Taraboulos, A., Scott, M., Semenov, A., Avraham, D., Laszlo, L., and Prusiner, S. B. (1995) J. Cell Biol. 129, 121-132.
22. Baron, G. S., Wehrly, K., Dorward, D. W., Chesebro, B., and Caughey, B. (2002) EMBO J. 21, 1031-1040.
23. Caughey, B. (1991) Sem. Virol. 2, 189-196.
24. Shyng, S.-L., Huber, M. T., and Harris, D. A. (1993) J. Biol. Chem. 268, 15922-15928.
25. DeArmond, S. J., and Prusiner, S. B. (1995) Am. J. Pathol. 146, 785-811.
26. Sanghera, N., and Pinheiro, T. J. T. (2002) J. Mol. Biol. 315, 1241-1256.
27. Mehlhorn, I., Groth, D., Stockel, J., Moffat, B., Reilly, D., Yansura, D., Willett, W. C., Baldwin, M., Fletterick, R., Cohen, F. E., Vandlen, R., Henner, D., and Prusiner, S. B. (1996) Biochemistry 35, 5528-5537.
28. Gill, S. C., and Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
29. Rankin, S. E., Watts, A., and Pinheiro, T. J. T. (1998) Biochemistry 37, 12588-12595.
30. Fringeli, U. P., and Günthard, H. H. (1981) Mol. Biol. Biochem. Biophys. 31, 270-332.
31. Goormaghtigh, E., Cabiaux, V., and Ruysschaert, J.-M. (1990) Eur. J. Biochem. 193, 409-420.
32. Raussens, V., Ruysschaert, J.-M., and Goormaghtigh, E. (1997) J. Biol. Chem. 272, 262-270.
33. Cabiaux, V., Brasseur, R., Wattiez, R., Falmagne, P., Ruysschaert, J.-M., and Goormaghtigh, E. (1989) J. Biol. Chem. 264, 4928-4938.
34. Defrise-Quertain, F., Cabiuax, V., Vandenbranden, M., Wattiez, R., Falmagne, P., and Ruysschaert, J.-M. (1989) Biochemistry 28, 3406-3413.
35. Butko, P., Huang, F., Pusztai-Carey, M., and Surewicz, W. K. (1996) Biochemistry 35, 11355-11360.
36. Vogt, T. C. B., and Bechinger, B. (1999) J. Mol. Biol. 274, 29115-29121.
37. James, T. L., Liu, H., Ulyanov, N. B., Farr-Jones, S., Zhang, H., Donne, D. G., Kaneko, K., Groth, D., Mehlhorn, I., Prusiner, S. B., and Cohen, F. E. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 10086-10091.
38. Schroeder, R., London, E., and Brown, D. (1994) Proc. Natl. Acad. Sci. U.S.A. 91, 12130-12134.
39. Swietnicki, W., Petersen, R. B., Gambetti, P., and Surewicz, W. K. (1997) Biol. Chem. 272, 27517-27520.
40. White, S. H., and Wimley, W. C. (1994) Curr. Opin. Struct. Biol. 4, 79-86.
41. Forloni, G., Angeretti, N., Chiesa, R., Monzani, E., Salmona, M., Bugiani, O., and Tagliavini, F. (1993) Nature 362, 543-546.
42. Brown, D. R., Schmidt, B., and Kretzschmar, H. A. (1996) Nature 380, 345-347.
43. Brown, D. R., Schulz-Schaeffer, W. J., Schmidt, B., and Kretzschmar, H. A. (1997) Exp. Neurol. 146, 104-112.
44. Pillot, T., Lins, L., Goethals, M., Vanloo, B., Baert, J., Vandekerckhove, J., Rosseneu, M., and Brasseur, R. (1997) J. Mol. Biol. 274, 381-393.
45. Lin, M.-C., Mirzabekov, T., and Kagan, B. L. (1997) J. Biol. Chem. 272, 44-47.
46. Brandner, S., Isenmann, S., Raeber, A., Fischer, M., Sailer, A., Kobayashi, Y., Marino, S., Weissmann, C., and Aguzzi, A. (1996) Nature 379, 339-343.
47. Caughey, B. (2001) Trends Biochem. Sci. 26, 235-242.
48. Borchelt, D. R., Taraboulos, A., and Prusiner, S. B. (1992) J. Biol. Chem. 267, 16188-16199.
49. Prats, M., Teissié, J., and Toccane, J. F. (1986) Nature 322, 756-758.
50. Hornemann, S., and Glockshuber, R. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 6010-6014.
51. Turk, E., Teplow, D. B., Hood, L. E., and Prusiner S. B. (1988) Eur. J. Biochem. 176, 21-30.
52. Welker, E., Raymond, L. D., Scheraga, H. A., and Caughey, B. (2002) J. Biol. Chem. 277, 33477-33481.
53. Harper, J. D., Wong, S. S., Lieber, C. M., and Lansbury, P. T. (1999) Biochemistry 38, 8972-8980.