메뉴 건너뛰기




Volumn 153, Issue 2, 2008, Pages 162-173

Translational mini-review series on the immunogenetics of gut disease: Immunogenetics of coeliac disease

Author keywords

Autoimmune; Coeliac; Genetics; Genome wide association; Immunogenetics

Indexed keywords

EPITOPE; GLUTEN; HLA B8 ANTIGEN; HLA DQ2 ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR3 ANTIGEN; HLA DR5 ANTIGEN; HLA DR7 ANTIGEN; INTERLEUKIN 12P35; INTERLEUKIN 2; INTERLEUKIN 21;

EID: 47249136580     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03704.x     Document Type: Short Survey
Times cited : (47)

References (118)
  • 1
    • 33745493934 scopus 로고    scopus 로고
    • Recent advances in coeliac disease
    • van Heel DA, West J. Recent advances in coeliac disease. Gut 2006 55:1037 46.
    • (2006) Gut , vol.55 , pp. 1037-46
    • Van Heel, D.A.1    West, J.2
  • 2
    • 34347324029 scopus 로고    scopus 로고
    • A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
    • van Heel DA, Franke L, Hunt KA et al. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet 2007 39:827 9.
    • (2007) Nat Genet , vol.39 , pp. 827-9
    • Van Heel, D.A.1    Franke, L.2    Hunt, K.A.3
  • 3
    • 41349103493 scopus 로고    scopus 로고
    • Newly identified genetic risk variants for celiac disease related to the immune response
    • Hunt KA, Zhernakova A, Turner G et al. Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 2008.
    • (2008) Nat Genet
    • Hunt, K.A.1    Zhernakova, A.2    Turner, G.3
  • 4
    • 0038121812 scopus 로고    scopus 로고
    • Seroprevalence, correlates, and characteristics of undetected coeliac disease in England
    • West J, Logan RF, Hill PG et al. Seroprevalence, correlates, and characteristics of undetected coeliac disease in England. Gut 2003 52:960 5.
    • (2003) Gut , vol.52 , pp. 960-5
    • West, J.1    Logan, R.F.2    Hill, P.G.3
  • 5
    • 4444332757 scopus 로고    scopus 로고
    • The global village of celiac disease
    • Accomando S, Cataldo F. The global village of celiac disease. Dig Liver Dis 2004 36:492 8.
    • (2004) Dig Liver Dis , vol.36 , pp. 492-8
    • Accomando, S.1    Cataldo, F.2
  • 6
    • 0042632870 scopus 로고    scopus 로고
    • Biopsy-defined adult celiac disease in Asian-Canadians
    • Freeman HJ. Biopsy-defined adult celiac disease in Asian-Canadians. Can J Gastroenterol 2003 17:433 6.
    • (2003) Can J Gastroenterol , vol.17 , pp. 433-6
    • Freeman, H.J.1
  • 7
    • 0028044937 scopus 로고
    • Celiac disease in two sisters with a mother from Cape Verde Island, Africa: A clinical and genetic study
    • Bonamico M, Mariani P, Triglione P et al. Celiac disease in two sisters with a mother from Cape Verde Island, Africa: a clinical and genetic study. J Pediatr Gastroenterol Nutr 1994 18:96 9.
    • (1994) J Pediatr Gastroenterol Nutr , vol.18 , pp. 96-9
    • Bonamico, M.1    Mariani, P.2    Triglione, P.3
  • 8
    • 0037429081 scopus 로고    scopus 로고
    • Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: A large multicenter study
    • Fasano A, Berti I, Gerarduzzi T et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med 2003 163:286 92.
    • (2003) Arch Intern Med , vol.163 , pp. 286-92
    • Fasano, A.1    Berti, I.2    Gerarduzzi, T.3
  • 9
    • 0036667785 scopus 로고    scopus 로고
    • Consumption of wheat foodstuffs not a risk for celiac disease occurrence in Burkina Faso
    • Cataldo F, Lio D, Simpore J, Musumeci S. Consumption of wheat foodstuffs not a risk for celiac disease occurrence in Burkina Faso. J Pediatr Gastroenterol Nutr 2002 35:233 4.
    • (2002) J Pediatr Gastroenterol Nutr , vol.35 , pp. 233-4
    • Cataldo, F.1    Lio, D.2    Simpore, J.3    Musumeci, S.4
  • 10
    • 0035724782 scopus 로고    scopus 로고
    • The distribution of DQ genes in the Saharawi population provides only a partial explanation for the high celiac disease prevalence
    • Catassi C, Doloretta Macis M, Ratsch IM, De Virgiliis S, Cucca F. The distribution of DQ genes in the Saharawi population provides only a partial explanation for the high celiac disease prevalence. Tissue Antigens 2001 58:402 6.
    • (2001) Tissue Antigens , vol.58 , pp. 402-6
    • Catassi, C.1    Doloretta MacIs, M.2    Ratsch, I.M.3    De Virgiliis, S.4    Cucca, F.5
  • 11
    • 0035109676 scopus 로고    scopus 로고
    • Current approaches to diagnosis and treatment of celiac disease: An evolving spectrum
    • Fasano A, Catassi C. Current approaches to diagnosis and treatment of celiac disease: an evolving spectrum. Gastroenterology 2001 120:636 51.
    • (2001) Gastroenterology , vol.120 , pp. 636-51
    • Fasano, A.1    Catassi, C.2
  • 12
    • 0029011530 scopus 로고
    • Striking differences in the incidence of childhood celiac disease between Denmark and Sweden: A plausible explanation
    • Weile B, Cavell B, Nivenius K, Krasilnikoff PA. Striking differences in the incidence of childhood celiac disease between Denmark and Sweden: a plausible explanation. J Pediatr Gastroenterol Nutr 1995 21:64 8.
    • (1995) J Pediatr Gastroenterol Nutr , vol.21 , pp. 64-8
    • Weile, B.1    Cavell, B.2    Nivenius, K.3    Krasilnikoff, P.A.4
  • 13
    • 0031906953 scopus 로고    scopus 로고
    • Low cereal intake in Estonian infants: The possible explanation for the low frequency of coeliac disease in Estonia
    • Mitt K, Uibo O. Low cereal intake in Estonian infants: the possible explanation for the low frequency of coeliac disease in Estonia. Eur J Clin Nutr 1998 52:85 8.
    • (1998) Eur J Clin Nutr , vol.52 , pp. 85-8
    • Mitt, K.1    Uibo, O.2
  • 14
    • 35448995656 scopus 로고    scopus 로고
    • Increasing prevalence of coeliac disease over time
    • Lohi S, Mustalahti K, Kaukinen K et al. Increasing prevalence of coeliac disease over time. Aliment Pharmacol Ther 2007 26:1217 25.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 1217-25
    • Lohi, S.1    Mustalahti, K.2    Kaukinen, K.3
  • 15
    • 0034635768 scopus 로고    scopus 로고
    • Variation and trends in incidence of childhood diabetes in Europe
    • EURODIAB ACE Study Group.
    • EURODIAB ACE Study Group. Variation and trends in incidence of childhood diabetes in Europe. Lancet 2000 355:873 6.
    • (2000) Lancet , vol.355 , pp. 873-6
  • 17
    • 34547697884 scopus 로고    scopus 로고
    • Tissue transglutaminase and the stress response
    • Ientile R, Caccamo D, Griffin M. Tissue transglutaminase and the stress response. Amino Acids 2007 33:385 94.
    • (2007) Amino Acids , vol.33 , pp. 385-94
    • Ientile, R.1    Caccamo, D.2    Griffin, M.3
  • 19
    • 19944412520 scopus 로고    scopus 로고
    • The Swedish epidemic of coeliac disease explored using an epidemiological approach - Some lessons to be learnt
    • Ivarsson A. The Swedish epidemic of coeliac disease explored using an epidemiological approach - some lessons to be learnt. Best Pract Res 2005 19:425 40.
    • (2005) Best Pract Res , vol.19 , pp. 425-40
    • Ivarsson, A.1
  • 20
    • 0036177436 scopus 로고    scopus 로고
    • Coeliac disease is associated with intrauterine growth and neonatal infections
    • Sandberg-Bennich S, Dahlquist G, Kallen B. Coeliac disease is associated with intrauterine growth and neonatal infections. Acta Paediatr 2002 91:30 3.
    • (2002) Acta Paediatr , vol.91 , pp. 30-3
    • Sandberg-Bennich, S.1    Dahlquist, G.2    Kallen, B.3
  • 21
    • 33749175937 scopus 로고    scopus 로고
    • Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: A longitudinal study
    • Stene LC, Honeyman MC, Hoffenberg EJ et al. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol 2006 101:2333 40.
    • (2006) Am J Gastroenterol , vol.101 , pp. 2333-40
    • Stene, L.C.1    Honeyman, M.C.2    Hoffenberg, E.J.3
  • 22
    • 34948825770 scopus 로고    scopus 로고
    • Long-term follow-up of 61 coeliac patients diagnosed in childhood: Evolution toward latency is possible on a normal diet
    • Matysiak-Budnik T, Malamut G, de Serre NP et al. Long-term follow-up of 61 coeliac patients diagnosed in childhood: evolution toward latency is possible on a normal diet. Gut 2007 56:1379 86.
    • (2007) Gut , vol.56 , pp. 1379-86
    • Matysiak-Budnik, T.1    Malamut, G.2    De Serre, N.P.3
  • 23
    • 34548128782 scopus 로고    scopus 로고
    • Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study
    • Simell S, Hoppu S, Hekkala A et al. Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study. Am J Gastroenterol 2007 102:2026 35.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2026-35
    • Simell, S.1    Hoppu, S.2    Hekkala, A.3
  • 24
    • 0036109726 scopus 로고    scopus 로고
    • The first large population based twin study of coeliac disease
    • Greco L, Romino R, Coto I et al. The first large population based twin study of coeliac disease. Gut 2002 50:624 8.
    • (2002) Gut , vol.50 , pp. 624-8
    • Greco, L.1    Romino, R.2    Coto, I.3
  • 25
    • 0030660433 scopus 로고    scopus 로고
    • Genetic contribution of the HLA region to the familial clustering of coeliac disease
    • Petronzelli F, Bonamico M, Ferrante P et al. Genetic contribution of the HLA region to the familial clustering of coeliac disease. Ann Hum Genet 1997 61:307 17.
    • (1997) Ann Hum Genet , vol.61 , pp. 307-17
    • Petronzelli, F.1    Bonamico, M.2    Ferrante, P.3
  • 26
    • 0032854079 scopus 로고    scopus 로고
    • Contribution of the MHC region to the familial risk of coeliac disease
    • Bevan S, Popat S, Braegger CP et al. Contribution of the MHC region to the familial risk of coeliac disease. J Med Genet 1999 36:687 90.
    • (1999) J Med Genet , vol.36 , pp. 687-90
    • Bevan, S.1    Popat, S.2    Braegger, C.P.3
  • 27
    • 0023135007 scopus 로고
    • Assessing the role of HLA-linked and unlinked determinants of disease
    • Risch N. Assessing the role of HLA-linked and unlinked determinants of disease. Am J Hum Genet 1987 40:1 14.
    • (1987) Am J Hum Genet , vol.40 , pp. 1-14
    • Risch, N.1
  • 28
    • 36348953115 scopus 로고    scopus 로고
    • Estimating risks of common complex diseases across genetic and environmental factors: The example of Crohn disease
    • Lewis CM, Whitwell SC, Forbes A, Sanderson J, Mathew CG, Marteau TM. Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease. J Med Genet 2007 44:689 94.
    • (2007) J Med Genet , vol.44 , pp. 689-94
    • Lewis, C.M.1    Whitwell, S.C.2    Forbes, A.3    Sanderson, J.4    Mathew, C.G.5    Marteau, T.M.6
  • 29
    • 0037246882 scopus 로고    scopus 로고
    • IMGT/HLA and IMGT/MHC: Sequence databases for the study of the major histocompatibility complex
    • Robinson J, Waller MJ, Parham P et al. IMGT/HLA and IMGT/MHC: sequence databases for the study of the major histocompatibility complex. Nucleic Acids Res 2003 31:311 14.
    • (2003) Nucleic Acids Res , vol.31 , pp. 311-14
    • Robinson, J.1    Waller, M.J.2    Parham, P.3
  • 30
    • 0015352157 scopus 로고
    • Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathy
    • Falchuk ZM, Rogentine GN, Strober W. Predominance of histocompatibility antigen HL-A8 in patients with gluten-sensitive enteropathy. J Clin Invest 1972 51:1602 5.
    • (1972) J Clin Invest , vol.51 , pp. 1602-5
    • Falchuk, Z.M.1    Rogentine, G.N.2    Strober, W.3
  • 32
    • 0032902704 scopus 로고    scopus 로고
    • The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases
    • Price P, Witt C, Allcock R et al. The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases. Immunol Rev 1999 167:257 74.
    • (1999) Immunol Rev , vol.167 , pp. 257-74
    • Price, P.1    Witt, C.2    Allcock, R.3
  • 33
    • 0020599662 scopus 로고
    • Evidence that celiac disease is primarily associated with a DC locus allelic specificity
    • Tosi R, Vismara D, Tanigaki N et al. Evidence that celiac disease is primarily associated with a DC locus allelic specificity. Clin Immunol Immunopathol 1983 28:395 404.
    • (1983) Clin Immunol Immunopathol , vol.28 , pp. 395-404
    • Tosi, R.1    Vismara, D.2    Tanigaki, N.3
  • 35
    • 0142091358 scopus 로고    scopus 로고
    • The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses
    • Vader W, Stepniak D, Kooy Y et al. The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses. Proc Natl Acad Sci USA 2003 100:12390 5.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12390-5
    • Vader, W.1    Stepniak, D.2    Kooy, Y.3
  • 36
    • 0034121187 scopus 로고    scopus 로고
    • Molecular basis of celiac disease
    • Sollid LM. Molecular basis of celiac disease. Annu Rev Immunol 2000 18:53 81.
    • (2000) Annu Rev Immunol , vol.18 , pp. 53-81
    • Sollid, L.M.1
  • 37
    • 0036702792 scopus 로고    scopus 로고
    • HLA in coeliac disease families: A novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried
    • Louka AS, Nilsson S, Olsson M et al. HLA in coeliac disease families: a novel test of risk modification by the 'other' haplotype when at least one DQA1*05-DQB1*02 haplotype is carried. Tissue Antigens 2002 60:147 54.
    • (2002) Tissue Antigens , vol.60 , pp. 147-54
    • Louka, A.S.1    Nilsson, S.2    Olsson, M.3
  • 38
    • 3242748997 scopus 로고    scopus 로고
    • Defining the contribution of the HLA region to cis DQ2-positive coeliac disease patients
    • van Belzen MJ, Koeleman BP, Crusius JB et al. Defining the contribution of the HLA region to cis DQ2-positive coeliac disease patients. Genes Immun 2004 5:215 20.
    • (2004) Genes Immun , vol.5 , pp. 215-20
    • Van Belzen, M.J.1    Koeleman, B.P.2    Crusius, J.B.3
  • 39
    • 0024492512 scopus 로고
    • Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer
    • Sollid LM, Markussen G, Ek J, Gjerde H, Vartdal F, Thorsby E. Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med 1989 169:345 50.
    • (1989) J Exp Med , vol.169 , pp. 345-50
    • Sollid, L.M.1    Markussen, G.2    Ek, J.3    Gjerde, H.4    Vartdal, F.5    Thorsby, E.6
  • 40
    • 0027096778 scopus 로고
    • HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non DR3 or non-DR5/7
    • Spurkland A, Sollid LM, Polanco I, Vartdal F, Thorsby E. HLA-DR and -DQ genotypes of celiac disease patients serologically typed to be non DR3 or non-DR5/7. Hum Immunol 1992 35:188 92.
    • (1992) Hum Immunol , vol.35 , pp. 188-92
    • Spurkland, A.1    Sollid, L.M.2    Polanco, I.3    Vartdal, F.4    Thorsby, E.5
  • 41
    • 0037381091 scopus 로고    scopus 로고
    • HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: Results from the European Genetics Cluster on Celiac Disease
    • Karell K, Louka AS, Moodie SJ et al. HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease. Hum Immunol 2003 64:469 77.
    • (2003) Hum Immunol , vol.64 , pp. 469-77
    • Karell, K.1    Louka, A.S.2    Moodie, S.J.3
  • 42
    • 0037880603 scopus 로고    scopus 로고
    • HLA in coeliac disease: Unravelling the complex genetics of a complex disorder
    • Louka AS, Sollid LM. HLA in coeliac disease: unravelling the complex genetics of a complex disorder. Tissue Antigens 2003 61:105 17.
    • (2003) Tissue Antigens , vol.61 , pp. 105-17
    • Louka, A.S.1    Sollid, L.M.2
  • 43
    • 0037371211 scopus 로고    scopus 로고
    • A collaborative European search for non-DQA1*05-DQB1*02 celiac disease loci on HLA-DR3 haplotypes: Analysis of transmission from homozygous parents
    • Louka AS, Moodie SJ, Karell K et al. A collaborative European search for non-DQA1*05-DQB1*02 celiac disease loci on HLA-DR3 haplotypes: analysis of transmission from homozygous parents. Hum Immunol 2003 64:350 8.
    • (2003) Hum Immunol , vol.64 , pp. 350-8
    • Louka, A.S.1    Moodie, S.J.2    Karell, K.3
  • 44
    • 0034744360 scopus 로고    scopus 로고
    • Existence of a genetic risk factor on chromosome 5q in Italian coeliac disease families
    • Greco L, Babron MC, Corazza GR et al. Existence of a genetic risk factor on chromosome 5q in Italian coeliac disease families. Ann Hum Genet 2001 65:35 41.
    • (2001) Ann Hum Genet , vol.65 , pp. 35-41
    • Greco, L.1    Babron, M.C.2    Corazza, G.R.3
  • 46
    • 0141817736 scopus 로고    scopus 로고
    • A major non-HLA locus in celiac disease maps to chromosome 19
    • Van Belzen MJ, Meijer JW, Sandkuijl LA et al. A major non-HLA locus in celiac disease maps to chromosome 19. Gastroenterology 2003 125:1032 41.
    • (2003) Gastroenterology , vol.125 , pp. 1032-41
    • Van Belzen, M.J.1    Meijer, J.W.2    Sandkuijl, L.A.3
  • 47
    • 0031825969 scopus 로고    scopus 로고
    • CTLA-4 gene polymorphism is associated with predisposition to coeliac disease
    • Djilali-Saiah I, Schmitz J, Harfouch-Hammoud E CTLA-4 gene polymorphism is associated with predisposition to coeliac disease. Gut 1998 43:187 9.
    • (1998) Gut , vol.43 , pp. 187-9
    • Djilali-Saiah, I.1    Schmitz, J.2    Harfouch-Hammoud, E.3
  • 48
    • 28444452580 scopus 로고    scopus 로고
    • Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
    • Monsuur AJ, de Bakker PI, Alizadeh BZ et al. Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet 2005 37:1341 4.
    • (2005) Nat Genet , vol.37 , pp. 1341-4
    • Monsuur, A.J.1    De Bakker, P.I.2    Alizadeh, B.Z.3
  • 49
    • 33646574535 scopus 로고    scopus 로고
    • Lack of association of MYO9B genetic variants with coeliac disease in a British cohort
    • Hunt KA, Monsuur AJ, McArdle WL et al. Lack of association of MYO9B genetic variants with coeliac disease in a British cohort. Gut 2006 55:969 72.
    • (2006) Gut , vol.55 , pp. 969-72
    • Hunt, K.A.1    Monsuur, A.J.2    McArdle, W.L.3
  • 50
    • 33646552094 scopus 로고    scopus 로고
    • Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort
    • Amundsen SS, Monsuur AJ, Wapenaar MC et al. Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort. Hum Immunol 2006 67:341 5.
    • (2006) Hum Immunol , vol.67 , pp. 341-5
    • Amundsen, S.S.1    Monsuur, A.J.2    Wapenaar, M.C.3
  • 51
    • 34250365731 scopus 로고    scopus 로고
    • MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population
    • Sanchez E, Alizadeh BZ, Valdigem G et al. MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population. Hum Immunol 2007 68:610 15.
    • (2007) Hum Immunol , vol.68 , pp. 610-15
    • Sanchez, E.1    Alizadeh, B.Z.2    Valdigem, G.3
  • 52
    • 0019468245 scopus 로고
    • The timing of histological damage following a single challenge with gluten in treated coeliac disease
    • Anand BS, Piris J, Jerrome DW, Offord RE, Truelove SC. The timing of histological damage following a single challenge with gluten in treated coeliac disease. Q J Med 1981 50:83 94.
    • (1981) Q J Med , vol.50 , pp. 83-94
    • Anand, B.S.1    Piris, J.2    Jerrome, D.W.3    Offord, R.E.4    Truelove, S.C.5
  • 53
    • 0031660029 scopus 로고    scopus 로고
    • Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease
    • Nilsen EM, Jahnsen FL, Lundin KE et al. Gluten induces an intestinal cytokine response strongly dominated by interferon gamma in patients with celiac disease. Gastroenterology 1998 115:551 63.
    • (1998) Gastroenterology , vol.115 , pp. 551-63
    • Nilsen, E.M.1    Jahnsen, F.L.2    Lundin, K.E.3
  • 54
    • 3242713016 scopus 로고    scopus 로고
    • Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa
    • Monteleone I, Monteleone G, Vecchio Blanco DG et al. Regulation of the T helper cell type 1 transcription factor T-bet in coeliac disease mucosa. Gut 2004 53:1090 5.
    • (2004) Gut , vol.53 , pp. 1090-5
    • Monteleone, I.1    Monteleone, G.2    Vecchio Blanco, D.G.3
  • 55
    • 34848853541 scopus 로고    scopus 로고
    • Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease
    • Di Sabatino A, Pickard KM, Gordon JN et al. Evidence for the role of interferon-alfa production by dendritic cells in the Th1 response in celiac disease. Gastroenterology 2007 133:1175 87.
    • (2007) Gastroenterology , vol.133 , pp. 1175-87
    • Di Sabatino, A.1    Pickard, K.M.2    Gordon, J.N.3
  • 56
    • 0036155753 scopus 로고    scopus 로고
    • Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease
    • Salvati VM, MacDonald TT, Bajaj-Elliott M et al. Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease. Gut 2002 50:186 90.
    • (2002) Gut , vol.50 , pp. 186-90
    • Salvati, V.M.1    MacDonald, T.T.2    Bajaj-Elliott, M.3
  • 57
    • 0035063548 scopus 로고    scopus 로고
    • Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease
    • Monteleone G, Pender SL, Alstead E et al. Role of interferon alpha in promoting T helper cell type 1 responses in the small intestine in coeliac disease. Gut 2001 48:425 9.
    • (2001) Gut , vol.48 , pp. 425-9
    • Monteleone, G.1    Pender, S.L.2    Alstead, E.3
  • 58
    • 33750877346 scopus 로고    scopus 로고
    • Interleukin 18 maintains a long-standing inflammation in coeliac disease patients
    • Leon AJ, Garrote JA, Blanco-Quiros A et al. Interleukin 18 maintains a long-standing inflammation in coeliac disease patients. Clin Exp Immunol 2006 146:479 85.
    • (2006) Clin Exp Immunol , vol.146 , pp. 479-85
    • Leon, A.J.1    Garrote, J.A.2    Blanco-Quiros, A.3
  • 59
    • 33744540439 scopus 로고    scopus 로고
    • A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells
    • Raki M, Tollefsen S, Molberg O, Lundin KE, Sollid LM, Jahnsen FL. A unique dendritic cell subset accumulates in the celiac lesion and efficiently activates gluten-reactive T cells. Gastroenterology 2006 131:428 38.
    • (2006) Gastroenterology , vol.131 , pp. 428-38
    • Raki, M.1    Tollefsen, S.2    Molberg, O.3    Lundin, K.E.4    Sollid, L.M.5    Jahnsen, F.L.6
  • 60
    • 0027319208 scopus 로고
    • Gliadin-specific, HLA-DQ (alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients
    • Lundin KE, Scott H, Hansen T et al. Gliadin-specific, HLA-DQ (alpha 1*0501,beta 1*0201) restricted T cells isolated from the small intestinal mucosa of celiac disease patients. J Exp Med 1993 178:187 96.
    • (1993) J Exp Med , vol.178 , pp. 187-96
    • Lundin, K.E.1    Scott, H.2    Hansen, T.3
  • 61
    • 0028556659 scopus 로고
    • T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8
    • Lundin KE, Scott H, Fausa O, Thorsby E, Sollid LM. T cells from the small intestinal mucosa of a DR4, DQ7/DR4, DQ8 celiac disease patient preferentially recognize gliadin when presented by DQ8. Hum Immunol 1994 41:285 91.
    • (1994) Hum Immunol , vol.41 , pp. 285-91
    • Lundin, K.E.1    Scott, H.2    Fausa, O.3    Thorsby, E.4    Sollid, L.M.5
  • 62
    • 0034695893 scopus 로고    scopus 로고
    • The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase
    • Arentz-Hansen H, Korner R, Molberg O et al. The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase. J Exp Med 2000 191:603 12.
    • (2000) J Exp Med , vol.191 , pp. 603-12
    • Arentz-Hansen, H.1    Korner, R.2    Molberg, O.3
  • 63
    • 0034066695 scopus 로고    scopus 로고
    • In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope
    • Anderson RP, Degano P, Godkin AJ, Jewell DP, Hill AV. In vivo antigen challenge in celiac disease identifies a single transglutaminase-modified peptide as the dominant A-gliadin T-cell epitope. Nat Med 2000 6:337 42.
    • (2000) Nat Med , vol.6 , pp. 337-42
    • Anderson, R.P.1    Degano, P.2    Godkin, A.J.3    Jewell, D.P.4    Hill, A.V.5
  • 64
    • 23944522279 scopus 로고    scopus 로고
    • T cells in peripheral blood after gluten challenge in coeliac disease
    • Anderson RP, van Heel DA, Tye-Din JA et al. T cells in peripheral blood after gluten challenge in coeliac disease. Gut 2005 54:1217 23.
    • (2005) Gut , vol.54 , pp. 1217-23
    • Anderson, R.P.1    Van Heel, D.A.2    Tye-Din, J.A.3
  • 65
    • 0036724918 scopus 로고    scopus 로고
    • Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues
    • Arentz-Hansen H, McAdam SN, Molberg O et al. Celiac lesion T cells recognize epitopes that cluster in regions of gliadins rich in proline residues. Gastroenterology 2002 123:803 9.
    • (2002) Gastroenterology , vol.123 , pp. 803-9
    • Arentz-Hansen, H.1    McAdam, S.N.2    Molberg, O.3
  • 66
    • 0036082955 scopus 로고    scopus 로고
    • The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides
    • Vader W, Kooy Y, Van Veelen P et al. The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides. Gastroenterology 2002 122:1729 37.
    • (2002) Gastroenterology , vol.122 , pp. 1729-37
    • Vader, W.1    Kooy, Y.2    Van Veelen, P.3
  • 67
    • 2142764316 scopus 로고    scopus 로고
    • Identification of a gliadin T-cell epitope in coeliac disease: General importance of gliadin deamidation for intestinal T-cell recognition
    • Sjostrom H, Lundin KE, Molberg O et al. Identification of a gliadin T-cell epitope in coeliac disease: general importance of gliadin deamidation for intestinal T-cell recognition. Scand J Immunol 1998 48:111 15.
    • (1998) Scand J Immunol , vol.48 , pp. 111-15
    • Sjostrom, H.1    Lundin, K.E.2    Molberg, O.3
  • 68
    • 33746694192 scopus 로고    scopus 로고
    • HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease
    • Tollefsen S, Arentz-Hansen H, Fleckenstein B et al. HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease. J Clin Invest 2006 116:2226 36.
    • (2006) J Clin Invest , vol.116 , pp. 2226-36
    • Tollefsen, S.1    Arentz-Hansen, H.2    Fleckenstein, B.3
  • 69
    • 10244264710 scopus 로고    scopus 로고
    • The peptide binding motif of the disease associated HLA-DQ (alpha 1*0501, beta 1*0201) molecule
    • Vartdal F, Johansen BH, Friede T et al. The peptide binding motif of the disease associated HLA-DQ (alpha 1*0501, beta 1*0201) molecule. Eur J Immunol 1996 26:2764 72.
    • (1996) Eur J Immunol , vol.26 , pp. 2764-72
    • Vartdal, F.1    Johansen, B.H.2    Friede, T.3
  • 71
    • 0030968736 scopus 로고    scopus 로고
    • Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2)
    • Godkin A, Friede T, Davenport M et al. Use of eluted peptide sequence data to identify the binding characteristics of peptides to the insulin-dependent diabetes susceptibility allele HLA-DQ8 (DQ 3.2). Int Immunol 1997 9:905 11.
    • (1997) Int Immunol , vol.9 , pp. 905-11
    • Godkin, A.1    Friede, T.2    Davenport, M.3
  • 72
    • 1642447710 scopus 로고    scopus 로고
    • Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease
    • Kim CY, Quarsten H, Bergseng E, Khosla C, Sollid LM. Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease. Proc Natl Acad Sci USA 2004 101:4175 9.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4175-9
    • Kim, C.Y.1    Quarsten, H.2    Bergseng, E.3    Khosla, C.4    Sollid, L.M.5
  • 73
    • 0032528813 scopus 로고    scopus 로고
    • Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity
    • van de Wal Y, Kooy Y, van Veelen P et al. Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. J Immunol 1998 161:1585 8.
    • (1998) J Immunol , vol.161 , pp. 1585-8
    • Van De Wal, Y.1    Kooy, Y.2    Van Veelen, P.3
  • 74
    • 0030838044 scopus 로고    scopus 로고
    • Identification of tissue transglutaminase as the autoantigen of celiac disease
    • Dieterich W, Ehnis T, Bauer M et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med 1997 3:797 801.
    • (1997) Nat Med , vol.3 , pp. 797-801
    • Dieterich, W.1    Ehnis, T.2    Bauer, M.3
  • 75
    • 0031779478 scopus 로고    scopus 로고
    • Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    • Molberg O, McAdam SN, Korner R et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat Med 1998 4:713 17.
    • (1998) Nat Med , vol.4 , pp. 713-17
    • Molberg, O.1    McAdam, S.N.2    Korner, R.3
  • 76
    • 0037072829 scopus 로고    scopus 로고
    • Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
    • Fleckenstein B, Molberg O, Qiao SW et al. Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process. J Biol Chem 2002 277:34109 16.
    • (2002) J Biol Chem , vol.277 , pp. 34109-16
    • Fleckenstein, B.1    Molberg, O.2    Qiao, S.W.3
  • 77
    • 33749002571 scopus 로고    scopus 로고
    • In celiac disease, a subset of autoantibodies against transglutaminase binds Toll-like receptor 4 and induces activation of monocytes
    • Zanoni G, Navone R, Lunardi C et al. In celiac disease, a subset of autoantibodies against transglutaminase binds Toll-like receptor 4 and induces activation of monocytes. PLoS Med 2006 3:e358.
    • (2006) PLoS Med , vol.3
    • Zanoni, G.1    Navone, R.2    Lunardi, C.3
  • 79
    • 2342426804 scopus 로고    scopus 로고
    • In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies
    • Korponay-Szabo IR, Halttunen T, Szalai Z et al. In vivo targeting of intestinal and extraintestinal transglutaminase 2 by coeliac autoantibodies. Gut 2004 53:641 8.
    • (2004) Gut , vol.53 , pp. 641-8
    • Korponay-Szabo, I.R.1    Halttunen, T.2    Szalai, Z.3
  • 80
    • 33646177232 scopus 로고    scopus 로고
    • Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxia
    • Hadjivassiliou M, Maki M, Sanders DS et al. Autoantibody targeting of brain and intestinal transglutaminase in gluten ataxia. Neurology 2006 66:373 7.
    • (2006) Neurology , vol.66 , pp. 373-7
    • Hadjivassiliou, M.1    Maki, M.2    Sanders, D.S.3
  • 81
    • 0036784254 scopus 로고    scopus 로고
    • Intestinal digestive resistance of immunodominant gliadin peptides
    • G1003.
    • Hausch F, Shan L, Santiago NA, Gray GM, Khosla C. Intestinal digestive resistance of immunodominant gliadin peptides. Am J Physiol 2002 283:G996 G1003.
    • (2002) Am J Physiol , vol.283
    • Hausch, F.1    Shan, L.2    Santiago, N.A.3    Gray, G.M.4    Khosla, C.5
  • 82
    • 0028300097 scopus 로고
    • Wheat peptide challenge in coeliac disease
    • Sturgess R, Day P, Ellis HJ et al. Wheat peptide challenge in coeliac disease. Lancet 1994 343:758 61.
    • (1994) Lancet , vol.343 , pp. 758-61
    • Sturgess, R.1    Day, P.2    Ellis, H.J.3
  • 83
    • 0344234245 scopus 로고    scopus 로고
    • Coeliac disease: In vivo toxicity of the putative immunodominant epitope
    • Fraser JS, Engel W, Ellis HJ et al. Coeliac disease: in vivo toxicity of the putative immunodominant epitope. Gut 2003 52:1698 702.
    • (2003) Gut , vol.52 , pp. 1698-702
    • Fraser, J.S.1    Engel, W.2    Ellis, H.J.3
  • 84
    • 0029963596 scopus 로고    scopus 로고
    • Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients
    • Maiuri L, Picarelli A, Boirivant M et al. Definition of the initial immunologic modifications upon in vitro gliadin challenge in the small intestine of celiac patients. Gastroenterology 1996 110:1368 78.
    • (1996) Gastroenterology , vol.110 , pp. 1368-78
    • Maiuri, L.1    Picarelli, A.2    Boirivant, M.3
  • 85
    • 0038501062 scopus 로고    scopus 로고
    • Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease
    • Maiuri L, Ciacci C, Ricciardelli I et al. Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease. Lancet 2003 362:30 7.
    • (2003) Lancet , vol.362 , pp. 30-7
    • Maiuri, L.1    Ciacci, C.2    Ricciardelli, I.3
  • 86
    • 33645118120 scopus 로고    scopus 로고
    • Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease
    • Di Sabatino A, Ciccocioppo R, Cupelli F et al. Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease. Gut 2006 55:469 77.
    • (2006) Gut , vol.55 , pp. 469-77
    • Di Sabatino, A.1    Ciccocioppo, R.2    Cupelli, F.3
  • 87
    • 0042324649 scopus 로고    scopus 로고
    • Interleukin 15: A key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease
    • Mention JJ, Ben Ahmed M, Begue B et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology 2003 125:730 45.
    • (2003) Gastroenterology , vol.125 , pp. 730-45
    • Mention, J.J.1    Ben Ahmed, M.2    Begue, B.3
  • 88
    • 0034058876 scopus 로고    scopus 로고
    • Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease
    • Jabri B, de Serre NP, Cellier C et al. Selective expansion of intraepithelial lymphocytes expressing the HLA-E-specific natural killer receptor CD94 in celiac disease. Gastroenterology 2000 118:867 79.
    • (2000) Gastroenterology , vol.118 , pp. 867-79
    • Jabri, B.1    De Serre, N.P.2    Cellier, C.3
  • 89
    • 33646675580 scopus 로고    scopus 로고
    • Reprogramming of CTLs into natural killer-like cells in celiac disease
    • Meresse B, Curran SA, Ciszewski C et al. Reprogramming of CTLs into natural killer-like cells in celiac disease. J Exp Med 2006 203:1343 55.
    • (2006) J Exp Med , vol.203 , pp. 1343-55
    • Meresse, B.1    Curran, S.A.2    Ciszewski, C.3
  • 90
    • 4444251461 scopus 로고    scopus 로고
    • A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease
    • Hue S, Mention JJ, Monteiro RC et al. A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease. Immunity 2004 21:367 77.
    • (2004) Immunity , vol.21 , pp. 367-77
    • Hue, S.1    Mention, J.J.2    Monteiro, R.C.3
  • 91
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev 2005 6:95 108.
    • (2005) Nat Rev , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 92
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007 447:661 78.
    • (2007) Nature , vol.447 , pp. 661-78
  • 93
    • 38749145596 scopus 로고    scopus 로고
    • Shifting paradigm of association studies: Value of rare single-nucleotide polymorphisms
    • Gorlov IP, Gorlova OY, Sunyaev SR, Spitz MR, Amos CI. Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms. Am J Hum Genet 2008 82:100 12.
    • (2008) Am J Hum Genet , vol.82 , pp. 100-12
    • Gorlov, I.P.1    Gorlova, O.Y.2    Sunyaev, S.R.3    Spitz, M.R.4    Amos, C.I.5
  • 94
    • 35348988679 scopus 로고    scopus 로고
    • Paired-end mapping reveals extensive structural variation in the human genome
    • Korbel JO, Urban AE, Affourtit JP et al. Paired-end mapping reveals extensive structural variation in the human genome. Science 2007 318:420 6.
    • (2007) Science , vol.318 , pp. 420-6
    • Korbel, J.O.1    Urban, A.E.2    Affourtit, J.P.3
  • 95
    • 35948991932 scopus 로고    scopus 로고
    • Copy number variants and common disorders: Filling the gaps and exploring complexity in genome-wide association studies
    • Estivill X, Armengol L. Copy number variants and common disorders: filling the gaps and exploring complexity in genome-wide association studies. PLoS Genet 2007 3:1787 99.
    • (2007) PLoS Genet , vol.3 , pp. 1787-99
    • Estivill, X.1    Armengol, L.2
  • 96
    • 33746547247 scopus 로고    scopus 로고
    • The biology of interleukin-2 and interleukin-15: Implications for cancer therapy and vaccine design
    • Waldmann TA. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev 2006 6:595 601.
    • (2006) Nat Rev , vol.6 , pp. 595-601
    • Waldmann, T.A.1
  • 97
    • 0029863903 scopus 로고    scopus 로고
    • Fas and the art of lymphocyte maintenance
    • Lenardo MJ. Fas and the art of lymphocyte maintenance. J Exp Med 1996 183:721 4.
    • (1996) J Exp Med , vol.183 , pp. 721-4
    • Lenardo, M.J.1
  • 98
  • 99
    • 27544483288 scopus 로고    scopus 로고
    • Fueling regulation: IL-2 keeps CD4+ Treg cells fit
    • Maloy KJ, Powrie F. Fueling regulation: IL-2 keeps CD4+ Treg cells fit. Nat Immunol 2005 6:1071 2.
    • (2005) Nat Immunol , vol.6 , pp. 1071-2
    • Maloy, K.J.1    Powrie, F.2
  • 100
    • 33847246293 scopus 로고    scopus 로고
    • Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
    • Yamanouchi J, Rainbow D, Serra P et al. Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity. Nat Genet 2007 39:329 37.
    • (2007) Nat Genet , vol.39 , pp. 329-37
    • Yamanouchi, J.1    Rainbow, D.2    Serra, P.3
  • 101
    • 41549086943 scopus 로고    scopus 로고
    • Interleukin-21 contributes to the mucosal T helper cell type 1 response in celiac disease
    • online early.
    • Fina D, Sarra M, Caruso R et al. Interleukin-21 contributes to the mucosal T helper cell type 1 response in celiac disease. Gut 2007 online early.
    • (2007) Gut
    • Fina, D.1    Sarra, M.2    Caruso, R.3
  • 102
    • 25444434157 scopus 로고    scopus 로고
    • Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
    • Leonard WJ, Spolski R. Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation. Nat Rev 2005 5:688 98.
    • (2005) Nat Rev , vol.5 , pp. 688-98
    • Leonard, W.J.1    Spolski, R.2
  • 103
    • 37249006192 scopus 로고    scopus 로고
    • New links to the pathogenesis of Crohn disease provided by genome-wide association scans
    • Mathew CG. New links to the pathogenesis of Crohn disease provided by genome-wide association scans. Nat Rev Genet 2007 9:9 14.
    • (2007) Nat Rev Genet , vol.9 , pp. 9-14
    • Mathew, C.G.1
  • 104
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • Todd JA, Walker NM, Cooper JD et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007 39:857 64.
    • (2007) Nat Genet , vol.39 , pp. 857-64
    • Todd, J.A.1    Walker, N.M.2    Cooper, J.D.3
  • 105
    • 0142061069 scopus 로고    scopus 로고
    • The inter-relatedness and interdependence of mouse T cell receptor gammadelta+ and alphabeta+ cells
    • Pennington DJ, Silva-Santos B, Shires J et al. The inter-relatedness and interdependence of mouse T cell receptor gammadelta+ and alphabeta+ cells. Nat Immunol 2003 4:991 8.
    • (2003) Nat Immunol , vol.4 , pp. 991-8
    • Pennington, D.J.1    Silva-Santos, B.2    Shires, J.3
  • 106
    • 15244342101 scopus 로고    scopus 로고
    • Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles
    • Han SB, Moratz C, Huang NN et al. Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles. Immunity 2005 22:343 54.
    • (2005) Immunity , vol.22 , pp. 343-54
    • Han, S.B.1    Moratz, C.2    Huang, N.N.3
  • 107
    • 0034658354 scopus 로고    scopus 로고
    • Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation
    • Li Y, He X, Schembri-King J, Jakes S, Hayashi J. Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation. J Immunol 2000 164:5199 206.
    • (2000) J Immunol , vol.164 , pp. 5199-206
    • Li, Y.1    He, X.2    Schembri-King, J.3    Jakes, S.4    Hayashi, J.5
  • 108
    • 0037124306 scopus 로고    scopus 로고
    • Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice
    • Velazquez L, Cheng AM, Fleming HE et al. Cytokine signaling and hematopoietic homeostasis are disrupted in Lnk-deficient mice. J Exp Med 2002 195:1599 611.
    • (2002) J Exp Med , vol.195 , pp. 1599-611
    • Velazquez, L.1    Cheng, A.M.2    Fleming, H.E.3
  • 109
    • 38549092474 scopus 로고    scopus 로고
    • Membrane recognition by phospholipid-binding domains
    • Lemmon MA. Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol 2008 9:99 111.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 99-111
    • Lemmon, M.A.1
  • 110
    • 19944434293 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase: Cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling
    • Lindvall JM, Blomberg KE, Valiaho J et al. Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling. Immunol Rev 2005 203:200 15.
    • (2005) Immunol Rev , vol.203 , pp. 200-15
    • Lindvall, J.M.1    Blomberg, K.E.2    Valiaho, J.3
  • 111
    • 34547172596 scopus 로고    scopus 로고
    • A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
    • Carpten JD, Faber AL, Horn C et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature 2007 448:439 44.
    • (2007) Nature , vol.448 , pp. 439-44
    • Carpten, J.D.1    Faber, A.L.2    Horn, C.3
  • 112
    • 2642552976 scopus 로고    scopus 로고
    • T lymphocyte activation gene identification by coregulated expression on DNA microarrays
    • Mao M, Biery MC, Kobayashi SV et al. T lymphocyte activation gene identification by coregulated expression on DNA microarrays. Genomics 2004 83:989 99.
    • (2004) Genomics , vol.83 , pp. 989-99
    • Mao, M.1    Biery, M.C.2    Kobayashi, S.V.3
  • 114
    • 36749054721 scopus 로고    scopus 로고
    • Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases
    • Zhernakova A, Alizadeh BZ, Bevova M et al. Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases. Am J Hum Genet 2007 81:1284 8.
    • (2007) Am J Hum Genet , vol.81 , pp. 1284-8
    • Zhernakova, A.1    Alizadeh, B.Z.2    Bevova, M.3
  • 115
    • 43249083380 scopus 로고    scopus 로고
    • A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci
    • Liu Y, Helms C, Liao W et al. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet 2008 4:e1000041.
    • (2008) PLoS Genet , vol.4
    • Liu, Y.1    Helms, C.2    Liao, W.3
  • 116
    • 34547674870 scopus 로고    scopus 로고
    • Rotavirus infections and development of type 1 diabetes: An evasive conundrum
    • Ballotti S, de Martino M. Rotavirus infections and development of type 1 diabetes: an evasive conundrum. J Pediatr Gastroenterol Nutr 2007 45:147 56.
    • (2007) J Pediatr Gastroenterol Nutr , vol.45 , pp. 147-56
    • Ballotti, S.1    De Martino, M.2
  • 117
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn JN, Klannemark M et al. The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 2000 26:76 80.
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3
  • 118
    • 17844410419 scopus 로고    scopus 로고
    • Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: Population-based studies and meta-analyses
    • van Dam RM, Hoebee B, Seidell JC, Schaap MM, de Bruin TW, Feskens EJ. Common variants in the ATP-sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population-based studies and meta-analyses. Diabet Med 2005 22:590 8.
    • (2005) Diabet Med , vol.22 , pp. 590-8
    • Van Dam, R.M.1    Hoebee, B.2    Seidell, J.C.3    Schaap, M.M.4    De Bruin, T.W.5    Feskens, E.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.