Contribution of the MHC region to the familial risk of coeliac disease

Journal of Medical Genetics

Volumn 36, Issue 9, 1999, Pages 687-690

  Bevan, S ^a   Popat, S ^a   Braegger, C P ^b   Busch, A ^c   O'Donoghue, D ^d   Falth Magnusson, K ^e   Ferguson, A ^f   Godkin, A ^g   Hogberg, L ^h   Holmes, G ⁱ   Hosie, K B ^j   Howdle, P D ^k   Jenkins, H ^l   Jewell, D ^g   Johnston, S ^l   Kennedy, N P ^l   Kerr, G ^l   Kumar, P ^l   Logan, R F A ^l   Love, A H G ^l   Marsh, M ^l   Mulder, C J J ^l   Sjoberg, K ^l   Stenhammer, L ^h   Walker Smith, J ^l   Marossy, A M ^a   Houlston, R S ^a   more..

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^d ST VINCENT S UNIVERSITY HOSPITAL   (Ireland)

^e LINKÖPING UNIVERSITY   (Sweden)

^f WESTERN GENERAL HOSPITAL   (United Kingdom)

^g RADCLIFFE INFIRMARY   (United Kingdom)

^h Norrkoping Hospital   (Sweden)

ⁱ DERBYSHIRE ROYAL INFIRMARY   (United Kingdom)

^j NORTHERN GENERAL HOSPITAL   (United Kingdom)

^k ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^l NONE

more..

Author keywords

Coeliac disease; Familial risk; MHC

Indexed keywords

HLA DQ ANTIGEN;

ALLELE; ARTICLE; CELIAC DISEASE; FAMILIAL DISEASE; GENE LOCUS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; PREVALENCE; PRIORITY JOURNAL; PROBABILITY; RECURRENCE RISK; TWINS;

CELIAC DISEASE; FEMALE; HAPLOTYPES; HLA ANTIGENS; HUMANS; LOD SCORE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; RISK ASSESSMENT;

EID: 0032854079     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Marsh MN. Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ("celiac sprue"). Gastroenterology 1992;102:330-54.
2. Houlston RS, Ford D. Genetics of coeliac disease. Q J Med 1996;89:737-43.
3. Sollid LM, Thorsby E. HLA susceptibility genes in celiac disease: genetic mapping and role in pathogenesis. Gastroenterology 1993;105:910-22.
4. Kruglyak L, Lander ES. Complete multipoint sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 1995;57:439-54.
5. Risch N. Linkage stategies for genetically complex traits, IL The power of affected relative pairs. Am J Hum Genet 1990;46:229-41.
6. Mylotte M, Egan-Mitchell B, McCarthy CF, McNicholl B. Incidence of coeliac disease in the West of Ireland. BMJ 1973;i:703-5.
7. Logan RFA, Rifkind EA, Busuttil A, Gilmour HM, Ferguson A. Prevalence and "incidence" of celiac disease in Edinburgh and the Lothian region of Scotland, Gastroenterology 1986;90:334-42.
8. Midhagen G, Jarnerot G, Kraaz W. Adult coeliac disease within a defined geographic area in Sweden: a study of prevalence and associated diseases. Scand J Gastroenterol 1988;23:1000-4.
9. Greco L, Tozzi AE, Mayer M, Grimaldi M, Silano G, Auricchio S. Unchanging clinical picture of coeliac disease presentation in Campania, Italy. Eur J Pediatr 1989;148: 610-13.
10. Mann JG, Brown WR, Kern F Jr. The subtle and variable clinical expressions of gluten-induced enteropathy (adult celiac disease, nontropical sprue): an analysis of twenty-one cases. Am J Med 1970;48:357-66.
11. Logan RFA, Tucker G, Rifkind EA, Heading RC, Ferguson A. Changes in clinical features of coeliac disease in adults in Edinburgh and the Lothians 1960-79, BMJ 1983;286:95-7.
12. Grodzinsky E, Franzen L, Hed J, Strom M. High prevalence of coeliac disease in healthy adults revealed by antigliadin antibodies. Ann Allergy 1992;69:66-9.
13. Catassi C, Ratsch IM, Fabiani E, et al. Coeliac disease in year 2000: exploring the iceberg. Lancet 1994;343:200-3.
14. Falchuk ZM, Rogentine GM, Srober W. Predominence of histocompatability antigen HL-A8 in patients with gluten-sensitive enteropathy. J Clin Invest 1972;51:1602-6.
15. Asquit P. Family studies in celiac disease. In: Hekkens WTJ, Pena AS, eds. Celiac disease. Leiden: Krose, 1974:322-5.
16. Makintosh P, Asquit P. HLA and coeliac disease. Br Med Bull 1978;34:291-4.
17. Rosekrans PCM, Pena AS, Hekkens WTJM, De Vries RRP, Haex AJ. Coeliac disease. A family study in the Netherlands. In: McNicholl B, McCarthy CF, Fottrell PF, eds. Perspectives in coeliac disease. Lancaster: MTP Press, 1978:146-54.
18. Betuel H, Gebuhrer L, Descos L, Bertrand J, Freycon F, Lepetit JC, Celiac disease and its association with HLA markers. In: Terasaki PI, ed. Histocompatability testing. California: UCLA Tissue Typing Laboratory Publisher, 1980:668-72.
19. Polanco I, Biemond I, Van Leeuwen A, et al. Gluten sensitive enteropathy in Spain; genetic and environmental factors. In: McConnell RB, ed. The genetics of coeliac disease. Lancaster: MTP Press, 1986:211-31.
20. Orgad S, Avigad S, Jonas A, Mizrachi J, Gazit E. Immuno-genetics of childhood coeliac disease: the association with HLA DR3 and DR7 in unrelated patients and multiply affected families, Israel J Med Sci 1981;17:1041-4.
21. McKenna R, Stevens FM, McNicholl B, et al. Family and population studies of HLA and coeliac disease in the west of Ireland. Tissue Antigens 1983;22:175-81.
22. Mearin ML, Biemond I, Pena AS, et al. HLA-DR phenotypes in Spanish children: their contribution to the understanding of the genetics of the disease. Gut 1983;24: 532-7.
23. Scholtz S, Albert E. HLA and diseases: involvement of more than one HLA-linked determinant of disease susceptibility. Immunol Rev 1983;70:77-88.
24. Mearin ML, Bouquet J, Mourad N, et al. HLA-DR antigens and phenotypes in Dutch coeliac children and their families. Clin Genet 1985;27:45-50.
25. Caffrey C, Hitman GA, Niven MJ, et al. HLA-DP and celiac disease; family and population studies. Gut 1990;31:663-7.
26. Bolsover WJ, Hall MA, Vaughan RW, Welsh KI, Ciclitira PJ. A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype. Hum Immunol 1991;31:100-8.
27. Hernandez JL, Michalski JP, McCombs CC, McCarthy CF, Stevens FM, Elston RC. Evidence for a dominant gene mechanism underlying coeliac disease in the west of Ireland. Genet Epidemiol 1991;8:13-27.
28. Petronzelli F, Bonamico M, Ferrante P, et al. Genetic contribution of the HLA region to the familial clustering of coeliac disease. Ann Hum Genet 1997;61:307-17.
29. Greco L, Corazza G, Babron MC, et al. Genome search in celiac disease. Am J Hum Genet 1998;62:669-75.
30. Pena AS, Mann DL, Hague NE, et al. Genetic basis of glutensensitive enteropathy. Gastroenterology 1978;75:230-5.
31. Greenberg DA, Hodge SE, Rotter JI. Evidence for recessive and against dominant inheritance at the HLA-linked locus in coeliac disease. Am J Hum Genet 1982;34:263-77.