Acidic pH stimulates the production of the angiogenic CXC chemokine, CXCL8 (interleukin-8), in human adult mesenchymal stem cells via the extracellular signal-regulated kinase, p38 mitogen-activated protein kinase, and NF-κB pathways

Journal of Cellular Biochemistry

Volumn 104, Issue 4, 2008, Pages 1378-1392

  Bischoff, David S ^a,b   Zhu, Jian Hua ^a   Makhijani, Nalini S ^a   Yamaguchi, Dean T ^a,b  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acidic extracellular pH; ELR+ CXC chemokines; Human mesenchymal stem cells; Osteoblastic differentiation

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALPHA CHEMOKINE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PHOSPHOLIPASE C; PYRROLIDINE DITHIOCARBAMATE; U 0124;

ACIDITY; ANAEROBIC METABOLISM; ARTICLE; BLOOD VESSEL INJURY; BONE REMODELING; CELL PH; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OXYGEN DIFFUSION; OXYGEN TENSION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACIDS; ADULT; BONE REGENERATION; CELL DIFFERENTIATION; CELLS, CULTURED; DURAPATITE; HUMANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-8; MESENCHYMAL STEM CELLS; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION;

EID: 46949088934     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21714     Document Type: Article

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