Mechanism of the regulation of type IB phosphoinositide 3OH-kinase by G-protein βγ subunits

Biochemical Journal

Volumn 362, Issue 3, 2002, Pages 725-731

  Krugmann, Sonja ^a   Cooper, Matthew A ^a   Williams, Dudley H ^a   Hawkins, Phillip T ^a   Stephens, Len R ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

Heterotrimeric G protein; Neutrophil; PI3K; PtdIns(3,4,5)P3, signal transduction

Indexed keywords

CELL MEMBRANES; COMPOSITION; ENZYMES; PROTEINS; SEDIMENTATION;

CYTOSOL;

BIOCHEMISTRY;

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN BETAGAMMA SUBUNIT; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOINOSITIDE 3 HYDROXYKINASE 1B; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN COS7; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SUBSTRATE; INTRACELLULAR TRANSPORT; LEPIDOPTERA; LIPID ANALYSIS; LIPID COMPOSITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SEDIMENTATION; SOLUBILITY; SURFACE PLASMON RESONANCE; TRANSPORT KINETICS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DIMERIZATION; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HETEROTRIMERIC GTP-BINDING PROTEINS; KINETICS; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SPODOPTERA; SURFACE PLASMON RESONANCE; TRANSFECTION;

ANIMALIA; LEPIDOPTERA;

EID: 0037086679     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3620725     Document Type: Article

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