Delayed wound healing in CXCR 2 knockout mice

Journal of Investigative Dermatology

Volumn 115, Issue 2, 2000, Pages 234-244

  Devalaraja, Radhika M ^a   Nanney, Lillian B ^a   Qian, Qinghua ^a   Du, Jianguo ^a   Yu, Yingchun ^a   Devalaraja, Madhav N ^a   Richmond, Ann ^a,b,c  

^a Department of Cell Biology ^*  (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DEPARTMENT OF VETERANS AFFAIRS   (United States)

Author keywords

Angiogenesis; Chemokine; CXCR2; Keratinocyte; Neutrophils; Wound healing

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; KERATINOCYTE; KNOCKOUT MOUSE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; WOUND HEALING IMPAIRMENT;

EID: 0033883014     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.00034.x     Document Type: Article

References (50)

1. Augmented inflammatory response and altered wound healing in cathepsin G-deficient mice
2. The CXC, chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine induced angiogenic activity
3. Suppression of keratinocyte growth factor expression by glucocorticoids in vitro and during wound healing
4. Expression of the beta 6 integrin subunit in development, neoplasia and tissue repair suggests a role in epithelial remodeling
5. Expression of vascular permeability factor (Vascular Endothelial Growth Factor) by epidermal keratinocytes during wound healing
6. Neutrophil and B-cell expansion in mice that lack the murine IL-8 receptor homolog
7. Distinctive integrin expression in the newly forming epidermis during wound healing in humans
8. Classification of alpha2-macroglobulin-cytokine interactions based on affinity of noncovalent association in solution under apparent equilibrium conditions
9. Differential effects of neutrophil activating peptide I/IL-8 and its homologues on leukocyte adhesion and phagocytosis
10. Multiple chemotactic factors: Fine control or redundancy?
11. MIP 1-α as critical macrophage chemoattractant in murine wound repair
12. Chemokines IL-8, GRO-α MCP-1, IP-10 and Mig are sequentially and differentially expressed during phase-specific infiltration of leukocyte subsets in human wound healing
13. Chemokine and inflammatory cytokine changes during chronic wound healing
14. Transforming Growth Factors β1, β2, and β3 and their receptors are differentially regulated during and impaired wound healing
15. Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation
16. Monocyte chemoattractant protein-1 mRNA expression in the human bum wounds
17. Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration
18. Keratinocytes in human wounds express αvβ6 integrin
19. Angiogenic growth factors: Their effects and potential in soft tissue wound healing
20. Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice
21. Chrome inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1
22. The CXC receptor 2 is overexpressed in psoriatic epidermis
23. Chemokine binding and activities mediated by the mouse IL-8 receptor
24. The role of macrophage in wound repair
25. Delayed wound healing and disorganized neovascularization in transgenic mice expressing the IP-10 chemokine
26. Appearance of heparin-binding EGF-like growth factor in wound fluid as a response to injury
27. Wound healing - Aiming for perfect skin regeneration
28. Actin-based cell motility and cell locomotion
29. Epidermal and dermal effects of epidermal growth factor during wound repair
30. Biochemical and physiological aspects of wound healing
31. Distributiom of melanoma growth stimulatory activity or growth regulated gene and the interleukin-8 receptor B in human wound repair
32. Wound macrophages express TGF-alpha and other growth factors m vivo: Analysis by mRNA phenotyping
33. Role of melanocyte growth stimulatory activity on keratinocyte function in wound healing
34. Differential regulation of pro-inflammatory cytokines during wound healing in normal and glucocorticoid-treated mice
35. Differential expression of chemokines in patients with localized and diffused cutaneous American leishmaniasis
36. Assessment of differential cytokine effects on angiogenesis using an in vivo model of cutaneous wound repair
37. Cell biology of wound healing
38. Selective attraction of monocytes and lymphocytes of the memory phenotype by cytokine RANTES
39. Neutralisation of TGF-β 2 or exogenous addition of TGF-β 3 to cutaneous rat wounds reduces scarring
40. Neutrophilia in mice that lack the routine IL-8 receptor homulog
41. Localization of mRNAs representing collagenase and TIMP in sections of healing human burn wounds
42. Immunolocalization of collagenase and TIMP in healing human burn wounds
43. Preferential migration of activated CD4+ and CD8+ Tcells in response to MIP-1α and MIP-1β
44. The murine homulog of the interleukin-8 receptor CXCR model of acute urate crystal induced gouty sinovitis
45. Chemokine networks in vivo: Involvement of CXC and CC chemokines in neutrophil extravasation in vivo in response to TNF-α
46. Myeloperoxidase as a biomarker of skin irritation and inflammation
47. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1α and MIP-1β on human monocytes
48. Role of MIP-2 in neutrophil migration and tissue injury in the Herpes Simplex Virus-1-infected cornea
49. Human monocyte chemoattractant protein-1 (MCP-1). Full length cDNA cloning, expression in mitogen stimulated blood mononuclear leukocytes and sequence similarity to mouse competence gene JE
50. Dimethyl sulfoxide-induced enhancement of 1,12-dimerhyl benz(o)anthracene metabolism and DNA binding in differentiating mouse epidermal cell cultures