메뉴 건너뛰기




Volumn 45, Issue 1, 1996, Pages 1-14

Genetic analysis of NIDDM: The study of quantitative traits

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN RECEPTOR;

EID: 0030031579     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.1.1     Document Type: Review
Times cited : (98)

References (154)
  • 2
    • 0027409212 scopus 로고
    • Linkage analysis of "necessary" disease loci versus "susceptibility" loci
    • Greenberg DA: Linkage analysis of "necessary" disease loci versus "susceptibility" loci. Am J Hum Genet 52:135-143, 1993
    • (1993) Am J Hum Genet , vol.52 , pp. 135-143
    • Greenberg, D.A.1
  • 3
    • 0025094344 scopus 로고
    • Mapping genes in diabetes: Genetic epideiniological perspective
    • Rich SS: Mapping genes in diabetes: genetic epideiniological perspective Diabetes 39:1315-1319, 1990
    • (1990) Diabetes , vol.39 , pp. 1315-1319
    • Rich, S.S.1
  • 4
    • 0027273543 scopus 로고
    • Genetic determinants of type 2 diabetes mellitus: Lessons learned from family studies
    • Froguel P, Velho G, Passa PH, Cohen D Genetic determinants of type 2 diabetes mellitus: lessons learned from family studies Diabete & Metab 19:1-10, 1993
    • (1993) Diabete & Metab , vol.19 , pp. 1-10
    • Froguel, P.1    Velho, G.2    Passa, P.H.3    Cohen, D.4
  • 5
    • 0023680267 scopus 로고
    • Type 2 (non-insulin-dependent) diabetes mellitus: New genetics for old nightmares
    • O'Rahilly S, Wainscoat JS, Turner RC: Type 2 (non-insulin-dependent) diabetes mellitus: new genetics for old nightmares Diabetologia 31:407-414, 1988
    • (1988) Diabetologia , vol.31 , pp. 407-414
    • O'Rahilly, S.1    Wainscoat, J.S.2    Turner, R.C.3
  • 6
    • 0026849567 scopus 로고
    • Positional cloning. let's not call it reverse anymore
    • Collins FS. Positional cloning. let's not call it reverse anymore Nat Genet 1:3-6, 1992
    • (1992) Nat Genet , vol.1 , pp. 3-6
    • Collins, F.S.1
  • 7
    • 0026969347 scopus 로고
    • Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM)
    • Hamman RF: Genetic and environmental determinants of non-insulin-dependent diabetes mellitus (NIDDM). Diabetes Metab Rev 8:287-338, 1992
    • (1992) Diabetes Metab Rev , vol.8 , pp. 287-338
    • Hamman, R.F.1
  • 8
    • 0028229508 scopus 로고
    • Insulin resistance or insulin deficiency: Which is the primary cause of NIDDM?
    • Taylor SI, Accili D, Imai Y: Insulin resistance or insulin deficiency: which is the primary cause of NIDDM? Diabetes 43:735-740, 1994
    • (1994) Diabetes , vol.43 , pp. 735-740
    • Taylor, S.I.1    Accili, D.2    Imai, Y.3
  • 10
    • 0024834748 scopus 로고
    • Toward physiological understanding of glucose tolerance: Minimal-model approach
    • Bergman R: Toward physiological understanding of glucose tolerance: minimal-model approach. Diabetes 38:1512-1527, 1989
    • (1989) Diabetes , vol.38 , pp. 1512-1527
    • Bergman, R.1
  • 11
    • 0026638575 scopus 로고
    • Mapping diabetes-susceptibility genes: Lessons learned from search for DNA marker for maturity-onset diabetes of the young
    • Cox NJ, Xiang K-S, Fajans SS, Bell GI, Mapping diabetes-susceptibility genes: lessons learned from search for DNA marker for maturity-onset diabetes of the young. Diabetes 42:401-407, 1992
    • (1992) Diabetes , vol.42 , pp. 401-407
    • Cox, N.J.1    Xiang, K.-S.2    Fajans, S.S.3    Bell, G.I.4
  • 13
    • 0025820742 scopus 로고
    • Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus
    • Helmrich SP, Ragland DR, Leuiig RW, Paffenbarger RS Jr: Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus. N Engl J Med 325.147-152, 1991
    • (1991) N Engl J Med , vol.325 , pp. 147-152
    • Helmrich, S.P.1    Ragland, D.R.2    Leuiig, R.W.3    Paffenbarger Jr., R.S.4
  • 14
    • 0001795590 scopus 로고
    • Epidemiology and natural history of NIDDM: Non-obese and obese
    • Alberti KGMM, DeFronzo RA, Keen H, Zimmet P, Eds. New York, Wiley
    • Bennett PH, Bogardus C, Tuomilehto J, Zimmett P: Epidemiology and natural history of NIDDM: non-obese and obese. In International Textbook of Diabetes Mellitus. Alberti KGMM, DeFronzo RA, Keen H, Zimmet P, Eds. New York, Wiley, 1992, p 147-176
    • (1992) International Textbook of Diabetes Mellitus , pp. 147-176
    • Bennett, P.H.1    Bogardus, C.2    Tuomilehto, J.3    Zimmett, P.4
  • 15
    • 0024095149 scopus 로고
    • Gm and type 2 diabetes mellitus: An association in American Indians with genetic admixture
    • Knowler WC, Williams RC, Pettirt DJ, Steinberg AG: Gm and type 2 diabetes mellitus: an association in American Indians with genetic admixture. Am J Hum Genet 43:520-026, 1988
    • (1988) Am J Hum Genet , vol.43 , pp. 520-1026
    • Knowler, W.C.1    Williams, R.C.2    Pettirt, D.J.3    Steinberg, A.G.4
  • 16
    • 0022406686 scopus 로고
    • The Southall Diabetes Survey: Prevalence of diabetes in Asians and Europeans
    • Mather HM, Keen H: The Southall Diabetes Survey: prevalence of diabetes in Asians and Europeans. Br Med J 291:1081-1084, 1085
    • (1085) Br Med J , vol.291 , pp. 1081-1084
    • Mather, H.M.1    Keen, H.2
  • 17
    • 0028286694 scopus 로고
    • Fatty acid composition of erythrocytes and plasma triglyceride and cardiovascular risk in Asian diabetic patients
    • Peterson DB, Fisher K, Carter RD, Mann J: Fatty acid composition of erythrocytes and plasma triglyceride and cardiovascular risk in Asian diabetic patients. Lancet 343:1528-1530, 1994
    • (1994) Lancet , vol.343 , pp. 1528-1530
    • Peterson, D.B.1    Fisher, K.2    Carter, R.D.3    Mann, J.4
  • 18
    • 0026641354 scopus 로고
    • Concordance for type 1 (insulin-dependent) and type 2 non-insulin dependent diabetes mellilus in a population-based cohort of twins m Finland
    • Kaprio J, Tuomilehto J, Koskenvuo M, Romanov K, Reunanen A, Eriksson J, Stengard J, Kesaniemi YA: Concordance for type 1 (insulin-dependent) and type 2 (non-insulin dependent diabetes mellilus in a population-based cohort of twins m Finland Diabetologia 35:1060 - 1067, 1992
    • (1992) Diabetologia , vol.35 , pp. 1060-1067
    • Kaprio, J.1    Tuomilehto, J.2    Koskenvuo, M.3    Romanov, K.4    Reunanen, A.5    Eriksson, J.6    Stengard, J.7    Kesaniemi, Y.A.8
  • 21
    • 0015956449 scopus 로고
    • Studies on blood and urine glucose in Seminole Indians: Indications for segregation of a major gene
    • Elston RC, Namboodiri KK, Nino HV, Pollitzer WS: Studies on blood and urine glucose in Seminole Indians: indications for segregation of a major gene. Am J Hum Genet 26:13-34, 1974
    • (1974) Am J Hum Genet , vol.26 , pp. 13-34
    • Elston, R.C.1    Namboodiri, K.K.2    Nino, H.V.3    Pollitzer, W.S.4
  • 23
    • 0026526717 scopus 로고
    • Compound regressive models for family data
    • Bonney GE: Compound regressive models for family data. Human Heredily 42-28-41, 1992
    • (1992) Human Heredily , vol.42 , pp. 28-41
    • Bonney, G.E.1
  • 24
    • 0025019555 scopus 로고
    • Linkage strategies for genetically complex traits I. Multilocus models
    • Risch N: Linkage strategies for genetically complex traits I. Multilocus models. Am J of Hum Genet 46:222-228, 1990
    • (1990) Am J of Hum Genet , vol.46 , pp. 222-228
    • Risch, N.1
  • 25
    • 0027953703 scopus 로고
    • Insulin action, diabetogenes, and the cause of type II diabetes
    • Kahn CR, Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 43.1066-1084, 1994
    • (1994) Diabetes , vol.43 , pp. 1066-1084
    • Kahn, C.R.1
  • 27
    • 0024851989 scopus 로고
    • Disease associations chance, artifacts or susceptibility genes?
    • Cox NJ, Bell GI: Disease associations chance, artifacts or susceptibility genes? Diabetes 38:947-950, 1989
    • (1989) Diabetes , vol.38 , pp. 947-950
    • Cox, N.J.1    Bell, G.I.2
  • 28
    • 0027992091 scopus 로고
    • Comparison of statistics for candidate-gene association studies using cases and parents
    • Schaid DJ, Sommer SS: Comparison of statistics for candidate-gene association studies using cases and parents. Am J of Hum Genet 55 402-409, 1994
    • (1994) Am J of Hum Genet , vol.55 , pp. 402-409
    • Schaid, D.J.1    Sommer, S.S.2
  • 29
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman RC, McGinnis RE, Ewens WJ: Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet 52.506-516, 1993
    • (1993) Am J Hum Genet , vol.52 , pp. 506-516
    • Spielman, R.C.1    McGinnis, R.E.2    Ewens, W.J.3
  • 30
    • 0026494911 scopus 로고
    • A haplotype-based 'haplotype relative risk' approach to detecting allelic associations
    • Terwilliger JD, Ott J: A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered 42:337-340, 1992
    • (1992) Hum Hered , vol.42 , pp. 337-340
    • Terwilliger, J.D.1    Ott, J.2
  • 31
    • 0027521860 scopus 로고
    • The haplotype-relative-risk method for analysis of association in nuclear families
    • Knapp M, Seuchter SA, Baur MP: The haplotype-relative-risk method for analysis of association in nuclear families. Am J Hum Genet 52:1085-1093, 1993
    • (1993) Am J Hum Genet , vol.52 , pp. 1085-1093
    • Knapp, M.1    Seuchter, S.A.2    Baur, M.P.3
  • 32
    • 0027320812 scopus 로고
    • Associations of disease with genetic markers: Deja vu all over again
    • Kidd KK: Associations of disease with genetic markers: deja vu all over again. Am J Med Genet 48:71-73, 1993
    • (1993) Am J Med Genet , vol.48 , pp. 71-73
    • Kidd, K.K.1
  • 33
    • 0020599746 scopus 로고
    • Identification of a point mutation in the human insulin gene giving rise to a structurally abnormal insulin (insulin Chicago)
    • Krok SCM, Steiner DF, Rubenstein AH, Tager HS: Identification of a point mutation in the human insulin gene giving rise to a structurally abnormal insulin (insulin Chicago). Diabetes 32:872-875, 1983
    • (1983) Diabetes , vol.32 , pp. 872-875
    • Krok, S.C.M.1    Steiner, D.F.2    Rubenstein, A.H.3    Tager, H.S.4
  • 36
    • 0026849690 scopus 로고
    • Wallace DC Maternally transmitted diabetes and deafness associated with a 10.4kb mitochondrial DNA deletion
    • Ballinger SW, Schoffner JM, Hedaya EV, Trounce I, Polak MA, Koontz DA, Wallace DC Maternally transmitted diabetes and deafness associated with a 10.4kb mitochondrial DNA deletion. Nat Genet 1:308-371, 1992
    • (1992) Nat Genet , vol.1 , pp. 308-371
    • Ballinger, S.W.1    Schoffner, J.M.2    Hedaya, E.V.3    Trounce, I.4    Polak, M.A.5    Koontz, D.A.6
  • 38
    • 0028011772 scopus 로고
    • Maternal effect and familial aggregation in NIDDM
    • Thomas F, Balkan B, Vauzelle-Kervroedan F, Papoz L, Codiab-Inserm-Zeneca Study Group: Maternal effect and familial aggregation in NIDDM. Diabetes 43:63-67, 1994
    • (1994) Diabetes , vol.43 , pp. 63-67
    • Thomas, F.1    Balkan, B.2    Vauzelle-Kervroedan, F.3    Papoz, L.4
  • 40
    • 0003187513 scopus 로고
    • The genetic aspects of non-insukn-dependent diabetes mellitus
    • Leslie DG, Ed. New York, Wiley
    • McCarthy M, Hitman GA: The genetic aspects of non-insukn-dependent diabetes mellitus. In Causes of Diabetes. Leslie DG, Ed. New York, Wiley, 1992, p. 157-183
    • (1992) Causes of Diabetes , pp. 157-183
    • McCarthy, M.1    Hitman, G.A.2
  • 42
    • 0026032055 scopus 로고
    • Gene for non-insulin diabetes mellitus (maturityonset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q
    • Bell GI, Xiang K-S, Newman MV, Wu S-H, Wright LG, Fajans SS, Spielman RS, Cox NJ: Gene for non-insulin diabetes mellitus (maturityonset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q. Proc Natl Acad Sci USA 88:1484-1488, 1901
    • (1901) Proc Natl Acad Sci USA , vol.88 , pp. 1484-1488
    • Bell, G.I.1    Xiang, K.-S.2    Newman, M.V.3    Wu, S.-H.4    Wright, L.G.5    Fajans, S.S.6    Spielman, R.S.7    Cox, N.J.8
  • 44
    • 0026754672 scopus 로고
    • Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young
    • Velho G, Froguel P, Clement K, Pueyo ME, Rakotoambinina B, Zouali H, Passa P, Cohen D, Robert JJ. Primary pancreatic beta-cell secretory defect caused by mutations in glucokinase gene in kindreds of maturity onset diabetes of the young. Lancet 340:444-447, 1992
    • (1992) Lancet , vol.340 , pp. 444-447
    • Velho, G.1    Froguel, P.2    Clement, K.3    Pueyo, M.E.4    Rakotoambinina, B.5    Zouali, H.6    Passa, P.7    Cohen, D.8    Robert, J.J.9
  • 46
    • 0027157761 scopus 로고
    • Positive association in the absence of linkage suggests a minor role for the glucokinase gene in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus amongst South Indians
    • McCarthy MI, Hitchins M, Hitman GA, Cassell P, Hawrami K, Morton N, Mohan V, Ramachandran A, Snehalatha C, Vishwanathan M: Positive association in the absence of linkage suggests a minor role for the glucokinase gene in the pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus amongst South Indians. Diabetologia 36:633-641, 1993
    • (1993) Diabetologia , vol.36 , pp. 633-641
    • McCarthy, M.I.1    Hitchins, M.2    Hitman, G.A.3    Cassell, P.4    Hawrami, K.5    Morton, N.6    Mohan, V.7    Ramachandran, A.8    Snehalatha, C.9    Vishwanathan, M.10
  • 48
    • 0026710603 scopus 로고
    • Glucokinase gene is genetic marker for NIDDM in American blacks
    • Chiu KC, Province MA, Permutt MA: Glucokinase gene is genetic marker for NIDDM in American blacks. Diabetes 41:843-849, 1992
    • (1992) Diabetes , vol.41 , pp. 843-849
    • Chiu, K.C.1    Province, M.A.2    Permutt, M.A.3
  • 49
    • 0026681851 scopus 로고
    • A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles
    • Chiu KC, Province MA, Dowse GK, Zimmet PZ, Wagner G, Serjeantson S, Permutt MA: A genetic marker at the glucokinase gene locus for type 2 (non-insulin-dependent) diabetes mellitus in Mauritian Creoles. Diabetologia 35:632-638, 1992
    • (1992) Diabetologia , vol.35 , pp. 632-638
    • Chiu, K.C.1    Province, M.A.2    Dowse, G.K.3    Zimmet, P.Z.4    Wagner, G.5    Serjeantson, S.6    Permutt, M.A.7
  • 50
    • 0027170935 scopus 로고
    • Polymorphic microsatellite repeat markers at the glucokinase gene locus are positively associated with NIDDM in Japanese
    • Noda K, Matsutani A, Tanizawa Y, Neuman R, Kaneko T, Permutt MA, Kaku K: Polymorphic microsatellite repeat markers at the glucokinase gene locus are positively associated with NIDDM in Japanese. Diabetes 42:1147-1152, 1993
    • (1993) Diabetes , vol.42 , pp. 1147-1152
    • Noda, K.1    Matsutani, A.2    Tanizawa, Y.3    Neuman, R.4    Kaneko, T.5    Permutt, M.A.6    Kaku, K.7
  • 52
    • 0028215293 scopus 로고
    • Mutations in the glucokinase gene are not a major cause of late-onset type 2 (non-insulin-dependent) diabetes mellitus in Japanese patients
    • Nishi S, Hinata S, Matsukage T, Takeda J, Ichiyama A, Bell GI, Yoshimi T: Mutations in the glucokinase gene are not a major cause of late-onset type 2 (non-insulin-dependent) diabetes mellitus in Japanese patients. Diabetic Med 11:193-197, 1994
    • (1994) Diabetic Med , vol.11 , pp. 193-197
    • Nishi, S.1    Hinata, S.2    Matsukage, T.3    Takeda, J.4    Ichiyama, A.5    Bell, G.I.6    Yoshimi, T.7
  • 53
    • 0027390345 scopus 로고
    • Linkage analysis of the glucokinase locus in familial type 2 (non-insulin-dependent) diabetic pedigrees
    • Elbein S, Hotfman M, Chiu K, Tanizawa Y, Permutt MA: Linkage analysis of the glucokinase locus in familial type 2 (non-insulin-dependent) diabetic pedigrees Diabetologia 36:141-145, 1993
    • (1993) Diabetologia , vol.36 , pp. 141-145
    • Elbein, S.1    Hotfman, M.2    Chiu, K.3    Tanizawa, Y.4    Permutt, M.A.5
  • 56
    • 0028907339 scopus 로고
    • Positional cloning moves from perditional to traditional
    • Collins FS: Positional cloning moves from perditional to traditional. Nat Genet 9:347-350, 1995
    • (1995) Nat Genet , vol.9 , pp. 347-350
    • Collins, F.S.1
  • 57
    • 0028343233 scopus 로고
    • Automated construction of genetic linkage maps using an expert system (MultiMap): A human genome linkage map
    • Matise TC, Perlin M, Chakravarti A: Automated construction of genetic linkage maps using an expert system (MultiMap): a human genome linkage map Nat Genet 6:384-390, 1994
    • (1994) Nat Genet , vol.6 , pp. 384-390
    • Matise, T.C.1    Perlin, M.2    Chakravarti, A.3
  • 61
    • 0025828430 scopus 로고
    • A note on multiple testing procedures in linkage analysis
    • Risch N: A note on multiple testing procedures in linkage analysis. Am J Hum Genet 48:1058-1064, 1991
    • (1991) Am J Hum Genet , vol.48 , pp. 1058-1064
    • Risch, N.1
  • 62
    • 0027487931 scopus 로고
    • Gaussian models for genetic-linkage analysis using complete high-resolution maps of identity-by-descent
    • Feingold E, Brown PO, Siegmund D: Gaussian models for genetic-linkage analysis using complete high-resolution maps of identity-by-descent. Am J Hum Genet 53:234-251, 1993
    • (1993) Am J Hum Genet , vol.53 , pp. 234-251
    • Feingold, E.1    Brown, P.O.2    Siegmund, D.3
  • 63
    • 21344487467 scopus 로고
    • Markov processes for modelling and analyzing a new genetic mapping method
    • Feingold E: Markov processes for modelling and analyzing a new genetic mapping method. J Appl Prob 30:766-779, 1993
    • (1993) J Appl Prob , vol.30 , pp. 766-779
    • Feingold, E.1
  • 64
    • 0028090414 scopus 로고
    • Genetic dissection of complex traits
    • Lander ES, Schork NJ: Genetic dissection of complex traits. Science 265:2037-2048, 1994
    • (1994) Science , vol.265 , pp. 2037-2048
    • Lander, E.S.1    Schork, N.J.2
  • 65
    • 0022728801 scopus 로고
    • Effects of misspecifying genetic parameters in lod score analysis
    • Clerget-Darpoux F, Bonaiti-Pellie C, Hochez J: Effects of misspecifying genetic parameters in lod score analysis. Biometrics 42:393-399, 1986
    • (1986) Biometrics , vol.42 , pp. 393-399
    • Clerget-Darpoux, F.1    Bonaiti-Pellie, C.2    Hochez, J.3
  • 66
    • 0018150112 scopus 로고
    • The generalized sib pair IBD distribution: Its use in the detection of linkage
    • Suarez BK, Rice J, Reich T: The generalized sib pair IBD distribution: its use in the detection of linkage. Ann Hum Genet 42:87-94, 1978
    • (1978) Ann Hum Genet , vol.42 , pp. 87-94
    • Suarez, B.K.1    Rice, J.2    Reich, T.3
  • 67
    • 0025008677 scopus 로고
    • Linkage strategies for genetically complex traits. II, The power of affected relative pairs
    • Risch N. Linkage strategies for genetically complex traits. II, The power of affected relative pairs. Am J Hum Genet 46:229-241, 1900
    • (1900) Am J Hum Genet , vol.46 , pp. 229-241
    • Risch, N.1
  • 69
    • 0027529253 scopus 로고
    • Asymptotic properties of affected-sib-pair linkage analysis
    • Holmans P: Asymptotic properties of affected-sib-pair linkage analysis Am J Hum Genet 52:362-374, 1993
    • (1993) Am J Hum Genet , vol.52 , pp. 362-374
    • Holmans, P.1
  • 70
    • 0027171992 scopus 로고
    • Improved sib-pair linkage test for disease susceptibility loci
    • Faraway JJ: Improved sib-pair linkage test for disease susceptibility loci. Genet Epidemiol 10:225-233, 1993
    • (1993) Genet Epidemiol , vol.10 , pp. 225-233
    • Faraway, J.J.1
  • 71
    • 0025020461 scopus 로고
    • Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs
    • Risch N: Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet 46.242-253, 1990
    • (1990) Am J Hum Genet , vol.46 , pp. 242-253
    • Risch, N.1
  • 72
    • 0023894935 scopus 로고
    • The affected-pedigree-member method of linkage analysis
    • Weeks DE, Lange K: The affected-pedigree-member method of linkage analysis. Am J Hum Genet 42:315-326, 1988
    • (1988) Am J Hum Genet , vol.42 , pp. 315-326
    • Weeks, D.E.1    Lange, K.2
  • 73
    • 0026510552 scopus 로고
    • A multilocus extension of the affected-pedigree member method of linkage analysis
    • Weeks DE, Lange K A multilocus extension of the affected-pedigree member method of linkage analysis. Am J Hum Genet 50.859-808, 1992
    • (1992) Am J Hum Genet , vol.50 , pp. 859-1808
    • Weeks, D.E.1    Lange, K.2
  • 75
    • 0025245437 scopus 로고
    • Multipoint analysis of human quantitative genetic variation
    • Goldgar DE Multipoint analysis of human quantitative genetic variation Am J Hum Genet 47:957-967, 1990
    • (1990) Am J Hum Genet , vol.47 , pp. 957-967
    • Goldgar, D.E.1
  • 76
    • 0028947057 scopus 로고
    • Multipoint interval mapping of quantitative trait loci using sib pairs
    • Fulker DW, Cherney SS, Cardon LR: Multipoint interval mapping of quantitative trait loci using sib pairs. Am J Hum Genet 56:1224-1233, 1995
    • (1995) Am J Hum Genet , vol.56 , pp. 1224-1233
    • Fulker, D.W.1    Cherney, S.S.2    Cardon, L.R.3
  • 77
    • 0029046177 scopus 로고
    • Complete multi-point sib-pair analysis of qualitative and quantitative traits
    • Kruglyak L, Lander ES: Complete multi-point sib-pair analysis of qualitative and quantitative traits. Am J Hum Genet 57:439-454, 1995
    • (1995) Am J Hum Genet , vol.57 , pp. 439-454
    • Kruglyak, L.1    Lander, E.S.2
  • 78
    • 0026949420 scopus 로고
    • Linkage disequilibrium mapping in isolated founder populations, diastrophic dysplasia in Finland
    • Hastbacka J, Chapelle A, Katrila I, Sistonen P, Weaver A, Lander E: Linkage disequilibrium mapping in isolated founder populations, diastrophic dysplasia in Finland. Nat Genet 2.204-211, 1992
    • (1992) Nat Genet , vol.2 , pp. 204-211
    • Hastbacka, J.1    Chapelle, A.2    Katrila, I.3    Sistonen, P.4    Weaver, A.5    Lander, E.6
  • 79
    • 0023915850 scopus 로고
    • The detection of linkage disequilibrium between closely linked markers: RFLPs at the AJ-CIII apolipoprotein genes
    • Thompson EA, Deeb S, Walker D, Motulsky AG: The detection of linkage disequilibrium between closely linked markers: RFLPs at the AJ-CIII apolipoprotein genes. Am J Hum Genet 42:113-124, 1988
    • (1988) Am J Hum Genet , vol.42 , pp. 113-124
    • Thompson, E.A.1    Deeb, S.2    Walker, D.3    Motulsky, A.G.4
  • 80
    • 0028298036 scopus 로고
    • Maximum-likelihood estimation of gene location by linkage disequilibrium
    • Hill WG, Weir BS: Maximum-likelihood estimation of gene location by linkage disequilibrium. Am J Hum Genet 54:705-714, 1994
    • (1994) Am J Hum Genet , vol.54 , pp. 705-714
    • Hill, W.G.1    Weir, B.S.2
  • 81
    • 0028968329 scopus 로고
    • A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci
    • Terwilliger JD: A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more polymorphic marker loci. Am J Hum Genet 56:777-787, 1995
    • (1995) Am J Hum Genet , vol.56 , pp. 777-787
    • Terwilliger, J.D.1
  • 82
    • 0028141921 scopus 로고
    • Linkage disequilibrium patterns vary with chromosomal location: A case study from von Willebrand factor region
    • Watkins WS, Zenger R, O'Bnen E, Nyman D, Eriksson AW, Renlund M, Jorde LB: Linkage disequilibrium patterns vary with chromosomal location: a case study from von Willebrand factor region. Am J Hum Genet 55:348-355, 1994
    • (1994) Am J Hum Genet , vol.55 , pp. 348-355
    • Watkins, W.S.1    Zenger, R.2    O'Bnen, E.3    Nyman, D.4    Eriksson, A.W.5    Renlund, M.6    Jorde, L.B.7
  • 83
    • 0027989667 scopus 로고
    • Design and sample-size considerations in the detection of linkage disequilibrium with a disease locus
    • Olson JM, Wijsman EM: Design and sample-size considerations in the detection of linkage disequilibrium with a disease locus. Am J Hum Genet 55:574-580, 1994
    • (1994) Am J Hum Genet , vol.55 , pp. 574-580
    • Olson, J.M.1    Wijsman, E.M.2
  • 84
    • 0026724680 scopus 로고
    • Sensitivity of lod scores to changes in diagnostic status
    • Hodge SE, Greenberg DA: Sensitivity of lod scores to changes in diagnostic status. Am J Hum Genet 50:1053-1066, 1092
    • (1092) Am J Hum Genet , vol.50 , pp. 1053-1066
    • Hodge, S.E.1    Greenberg, D.A.2
  • 85
    • 0027370273 scopus 로고
    • Problems related to definitions and epidemiology of type 2 (non-insulin-dependent) diabetes mellitus: Studies throughout the world
    • Alberti KGMM: Problems related to definitions and epidemiology of type 2 (non-insulin-dependent) diabetes mellitus: studies throughout the world. Diabelologia 36:978-084, 1993
    • (1993) Diabelologia , vol.36 , pp. 978-1084
    • Alberti, K.G.M.M.1
  • 86
    • 13344292426 scopus 로고
    • WHO Exrpert Committee on Diabetes Mellitus. Second Report
    • Geneva, World Health Org.
    • World Health Organization: WHO Exrpert Committee on Diabetes Mellitus. Second Report. Geneva, World Health Org., 1980 (Tech. Rep. Ser., no. 64G)
    • (1980) Tech. Rep. Ser., No. 64G
  • 87
    • 0018602014 scopus 로고
    • Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance
    • National Diabetes Data Group: Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28:1039 - 1057, 1979
    • (1979) Diabetes , vol.28 , pp. 1039-1057
  • 88
    • 0028211642 scopus 로고
    • Fasting plasma glucose in screening for NIDDM in the US and Israel
    • Modan M, Harris MI: Fasting plasma glucose in screening for NIDDM in the US and Israel. Diabetes Care 17:436-439, 1994
    • (1994) Diabetes Care , vol.17 , pp. 436-439
    • Modan, M.1    Harris, M.I.2
  • 89
    • 0028204065 scopus 로고
    • Understanding oral glucose tolerance: Comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion
    • Phillips DIW, Clark PM, Hales CN, Osmond C: Understanding oral glucose tolerance: comparison of glucose or insulin measurements during the oral glucose tolerance test with specific measurements of insulin resistance and insulin secretion. Diabetic Med 11:286-292, 1994
    • (1994) Diabetic Med , vol.11 , pp. 286-292
    • Phillips, D.I.W.1    Clark, P.M.2    Hales, C.N.3    Osmond, C.4
  • 91
    • 0028947513 scopus 로고
    • Evidence for linkage between a region on chromosome 1p and the acute insulin response in Pima Indians
    • Thompson DB, Janssen RC, Ossowski VM, Prochazka M, Knowler WC, Bogardus C. Evidence for linkage between a region on chromosome 1p and the acute insulin response in Pima Indians. Diabetes 44:478-481, 1995
    • (1995) Diabetes , vol.44 , pp. 478-481
    • Thompson, D.B.1    Janssen, R.C.2    Ossowski, V.M.3    Prochazka, M.4    Knowler, W.C.5    Bogardus, C.6
  • 92
    • 0024215005 scopus 로고
    • Genetic analysis of glucose tolerance in inbred mouse strains: Evidence for polygenic control
    • Kaku K, Fiedorek FT Jr, Province M, Permutt MA: Genetic analysis of glucose tolerance in inbred mouse strains: evidence for polygenic control. Diabetes 37:707-713, 1088
    • (1088) Diabetes , vol.37 , pp. 707-713
    • Kaku, K.1    Fiedorek Jr., F.T.2    Province, M.3    Permutt, M.A.4
  • 93
    • 0019906750 scopus 로고
    • Estimating genetic and non-genetic components of variance for fasting glucose levels in pedigrees ascertained through non-insulin dependent diabetes
    • Beaty TH, Fajans SS: Estimating genetic and non-genetic components of variance for fasting glucose levels in pedigrees ascertained through non-insulin dependent diabetes. Ann Hum Genet 46:355-362, 1982
    • (1982) Ann Hum Genet , vol.46 , pp. 355-362
    • Beaty, T.H.1    Fajans, S.S.2
  • 94
    • 0023132190 scopus 로고
    • Partitioning the variability of fasting plasma glucose levels in pedigrees
    • Boehnke M, Moll PP, Kottke BA, Weidman WH: Partitioning the variability of fasting plasma glucose levels in pedigrees. Am J Epidemiol 125:679-689, 1987
    • (1987) Am J Epidemiol , vol.125 , pp. 679-689
    • Boehnke, M.1    Moll, P.P.2    Kottke, B.A.3    Weidman, W.H.4
  • 95
    • 0017165430 scopus 로고
    • Extensions to pedigree analysis. III. Variance components by the scoring method
    • Lange K, Westlake J, Spence MA: Extensions to pedigree analysis. III. Variance components by the scoring method. Ann Hum Genet 39:485-491, 1076
    • (1076) Ann Hum Genet , vol.39 , pp. 485-491
    • Lange, K.1    Westlake, J.2    Spence, M.A.3
  • 97
    • 0023239785 scopus 로고
    • Family resemblance for fasting blood glucose: The Jerusalem Lipid Research Clinic
    • Friedlander Y, Kark JD, Bar-On H: Family resemblance for fasting blood glucose: The Jerusalem Lipid Research Clinic. Clin Genet 32:222-234, 1987
    • (1987) Clin Genet , vol.32 , pp. 222-234
    • Friedlander, Y.1    Kark, J.D.2    Bar-On, H.3
  • 98
    • 0018520840 scopus 로고
    • Glucose clamp technique: A method for quantifying insulin secretion and reistance
    • De Fronzo RA, Tobin JD, Andreas R: Glucose clamp technique: a method for quantifying insulin secretion and reistance. Am J Physiol 237:E214-E223, 1979
    • (1979) Am J Physiol , vol.237
    • De Fronzo, R.A.1    Tobin, J.D.2    Andreas, R.3
  • 99
    • 0028567915 scopus 로고
    • Repeatability of insulin sensitivity and glucose effectiveness from the minimal model: Implications for study design
    • Steil GM, Murray J, Bergman RN, Buchanan TA: Repeatability of insulin sensitivity and glucose effectiveness from the minimal model: implications for study design. Diabetes 43 1365-1371, 1994
    • (1994) Diabetes , vol.43 , pp. 1365-1371
    • Steil, G.M.1    Murray, J.2    Bergman, R.N.3    Buchanan, T.A.4
  • 100
    • 0023120630 scopus 로고
    • Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycaemic glucose clamp
    • Bergman RN, Prager R, Volund A, Olefsky JM: Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycaemic glucose clamp J Clin Invest 79:790-800, 1987
    • (1987) J Clin Invest , vol.79 , pp. 790-800
    • Bergman, R.N.1    Prager, R.2    Volund, A.3    Olefsky, J.M.4
  • 101
    • 0022626715 scopus 로고
    • The insulin sensitivity index in nondiabetic man. correlation between clamp-derived and IVGTT-derived values
    • Beard JC, Bergman RN, Ward WK, Porte D Jr: The insulin sensitivity index in nondiabetic man. correlation between clamp-derived and IVGTT-derived values. Diabetes 35.362-369, 1986
    • (1986) Diabetes , vol.35 , pp. 362-369
    • Beard, J.C.1    Bergman, R.N.2    Ward, W.K.3    Porte Jr., D.4
  • 102
    • 0022388944 scopus 로고
    • Importance of glucose per se to intravenous glucose tolerance . comparison of the minimal-model prediction with direct measurements
    • Ader M, Pacini G, Yang YJ, Bergman RN: Importance of glucose per se to intravenous glucose tolerance . comparison of the minimal-model prediction with direct measurements. Diabetes 34.1092-1103, 1985
    • (1985) Diabetes , vol.34 , pp. 1092-1103
    • Ader, M.1    Pacini, G.2    Yang, Y.J.3    Bergman, R.N.4
  • 103
    • 0028304581 scopus 로고
    • Non-insulin-mediated glucose disappearance in subjects with IDDM: Discordance between experimental results and minimal model analysis
    • Quon MJ, Cochran C, Taylor SI, Eastman RC: Non-insulin-mediated glucose disappearance in subjects with IDDM: discordance between experimental results and minimal model analysis. Diabetes 43:890-896, 1994
    • (1994) Diabetes , vol.43 , pp. 890-896
    • Quon, M.J.1    Cochran, C.2    Taylor, S.I.3    Eastman, R.C.4
  • 105
    • 0026793446 scopus 로고
    • Role of glucose and insulin resistance in development of type 2 diabetes mellitus: Results of a 25-year follow-up study
    • Martin BC, Warram JH, Krowlewski AS, Bergman RN, Soeldner JS, Kahn CR: Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 340:925-929, 1992
    • (1992) Lancet , vol.340 , pp. 925-929
    • Martin, B.C.1    Warram, J.H.2    Krowlewski, A.S.3    Bergman, R.N.4    Soeldner, J.S.5    Kahn, C.R.6
  • 114
    • 0028316192 scopus 로고
    • Linkage analysis of acute insulin secretion with GLUT2 and glucokinase in Pima Indians and the identification of a missense mutation in GLUT2
    • Jansen RC, Bogardus C, Takeda J, Knowler WC, Thompson CB Linkage analysis of acute insulin secretion with GLUT2 and glucokinase in Pima Indians and the identification of a missense mutation in GLUT2. Diabetes 43:558-563. 1994
    • (1994) Diabetes , vol.43 , pp. 558-563
    • Jansen, R.C.1    Bogardus, C.2    Takeda, J.3    Knowler, W.C.4    Thompson, C.B.5
  • 117
    • 0023951171 scopus 로고
    • Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes
    • O'Rahilly S, Turner RC, Matthews DR: Impaired pulsatile secretion of insulin in relatives of patients with non-insulin-dependent diabetes. N Engl J Med 318:1225-1230, 1994
    • (1994) N Engl J Med , vol.318 , pp. 1225-1230
    • O'Rahilly, S.1    Turner, R.C.2    Matthews, D.R.3
  • 118
    • 0028339912 scopus 로고
    • Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM
    • Polonsky KS, Gumbiner B, Ostrega D, Griver K, Tager H, Henry RR: Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM Diabetes 43.871-877, 1994
    • (1994) Diabetes , vol.43 , pp. 871-877
    • Polonsky, K.S.1    Gumbiner, B.2    Ostrega, D.3    Griver, K.4    Tager, H.5    Henry, R.R.6
  • 119
    • 0024463227 scopus 로고
    • Hyperproinsulinaemia and amyloid in NIDDM. clues to etiology of islet β-cell dysfunction
    • Porte D Jr, Kahn SE: Hyperproinsulinaemia and amyloid in NIDDM. clues to etiology of islet β-cell dysfunction. Diabetes 38:1333-1336, 1989
    • (1989) Diabetes , vol.38 , pp. 1333-1336
    • Porte Jr., D.1    Kahn, S.E.2
  • 120
    • 0001077470 scopus 로고
    • The correlation between relatives on the supposition of Mendelian inheritance
    • Fisher RA: The correlation between relatives on the supposition of Mendelian inheritance. Trans R Soc Edinb 52:499-433, 1918
    • (1918) Trans R Soc Edinb , vol.52 , pp. 499-1433
    • Fisher, R.A.1
  • 121
    • 0027428494 scopus 로고
    • Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: Application in NOD mouse and human IDDM
    • Risch N, Ghosh S, Todd JA: Statistical evaluation of multiple-locus linkage data in experimental species and its relevance to human studies: application in NOD mouse and human IDDM. Am J Hum Genet 53 702-714, 1993
    • (1993) Am J Hum Genet , vol.53 , pp. 702-714
    • Risch, N.1    Ghosh, S.2    Todd, J.A.3
  • 123
    • 0017260120 scopus 로고
    • Application of the lod method to the detection of linkage between a quantitative trait and a qualitative marker: A simulation experiment
    • Lange K, Spence MA, Frank MB: Application of the lod method to the detection of linkage between a quantitative trait and a qualitative marker: a simulation experiment. Am J Hum Genet 28:167-172, 1976
    • (1976) Am J Hum Genet , vol.28 , pp. 167-172
    • Lange, K.1    Spence, M.A.2    Frank, M.B.3
  • 124
    • 0024508964 scopus 로고
    • Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps
    • Lander ES, Botstein D: Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121:185-199, 1989
    • (1989) Genetics , vol.121 , pp. 185-199
    • Lander, E.S.1    Botstein, D.2
  • 125
    • 0026047218 scopus 로고
    • Linkage analysis of quantitative traits. increased power by using selected samples
    • Carey G, Williamson J: Linkage analysis of quantitative traits. increased power by using selected samples. Am J Hum Genet 49:786-796, 1991
    • (1991) Am J Hum Genet , vol.49 , pp. 786-796
    • Carey, G.1    Williamson, J.2
  • 126
    • 33646942472 scopus 로고
    • A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
    • Haley CS, Knott SA: A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69.315-324, 1992
    • (1992) Heredity , vol.69 , pp. 315-324
    • Haley, C.S.1    Knott, S.A.2
  • 127
    • 0028224156 scopus 로고
    • Precision mapping of quantitative trait loci
    • Zeng Z-B: Precision mapping of quantitative trait loci. Genetics 136: 1457-1468, 1994
    • (1994) Genetics , vol.136 , pp. 1457-1468
    • Zeng, Z.-B.1
  • 128
    • 0027363428 scopus 로고
    • Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci
    • Zeng Z-B: Theoretical basis for separation of multiple linked gene effects in mapping quantitative trait loci. Proc Natl Acad Sci USA 90.10972-10970, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10972-110970
    • Zeng, Z.-B.1
  • 129
    • 0015309467 scopus 로고
    • The investigation of linkage between a quantitative trait and a marker locus
    • Haseman JK, Elston RC: The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19, 1972
    • (1972) Behav Genet , vol.2 , pp. 3-19
    • Haseman, J.K.1    Elston, R.C.2
  • 130
    • 0028236482 scopus 로고
    • A sib-pair approach to interval mapping of quantitative trait loci
    • Fulker DW, Cardon LR: A sib-pair approach to interval mapping of quantitative trait loci. Am J Hum Genet 54:1092-1103, 1994
    • (1994) Am J Hum Genet , vol.54 , pp. 1092-1103
    • Fulker, D.W.1    Cardon, L.R.2
  • 131
    • 0022649864 scopus 로고
    • The use of measured genotype information in the analysis of quantitative phenotypes in man
    • Boerwinkle E, Chakraborty R, Sing CF: The use of measured genotype information in the analysis of quantitative phenotypes in man. Ann Hum Genet 50:181-194, 1986
    • (1986) Ann Hum Genet , vol.50 , pp. 181-194
    • Boerwinkle, E.1    Chakraborty, R.2    Sing, C.F.3
  • 133
    • 0029061838 scopus 로고
    • Statistical methods for linkage analysis of complex traits from high resolution maps of identity-by-descent
    • Dupuis J, Brown PO, Siegmund D. Statistical methods for linkage analysis of complex traits from high resolution maps of identity-by-descent. Genetics 140:843-850, 1995
    • (1995) Genetics , vol.140 , pp. 843-850
    • Dupuis, J.1    Brown, P.O.2    Siegmund, D.3
  • 134
    • 0027430716 scopus 로고
    • Two-trait-locus linkage analysis: A powerful strategy for mapping complex genetic traits
    • Schork NJ, Boehnke M, Terwilliger JD, Ott J: Two-trait-locus linkage analysis: a powerful strategy for mapping complex genetic traits. Am J Hum Genet 53:1127-1136, 1993
    • (1993) Am J Hum Genet , vol.53 , pp. 1127-1136
    • Schork, N.J.1    Boehnke, M.2    Terwilliger, J.D.3    Ott, J.4
  • 135
    • 0028030120 scopus 로고
    • Two-locus disease models with two marker loci: The power of affected-sib-pair tests
    • Knapp M, Seuchter SA, Baur MP. Two-locus disease models with two marker loci: the power of affected-sib-pair tests. Am J Hum Genet 55:1030-1041, 1994
    • (1994) Am J Hum Genet , vol.55 , pp. 1030-1041
    • Knapp, M.1    Seuchter, S.A.2    Baur, M.P.3
  • 136
    • 0020519567 scopus 로고
    • Pedigree discriminant analysis: A method to identify monogenic segregation
    • Zlotnik LH, Elston RC, Namboodiri KK: Pedigree discriminant analysis: a method to identify monogenic segregation. Am J Med Genet 15:307-313, 1983
    • (1983) Am J Med Genet , vol.15 , pp. 307-313
    • Zlotnik, L.H.1    Elston, R.C.2    Namboodiri, K.K.3
  • 137
    • 0018941999 scopus 로고
    • Genetic analysis of von Willebrand's disease in two large pedigrees, a multivariate approach
    • Goldin LR, Elston RC, Graham JB, Miller CH Genetic analysis of von Willebrand's disease in two large pedigrees, a multivariate approach. Am J Med Genet 7:279-293, 1980
    • (1980) Am J Med Genet , vol.7 , pp. 279-293
    • Goldin, L.R.1    Elston, R.C.2    Graham, J.B.3    Miller, C.H.4
  • 138
    • 0016531626 scopus 로고
    • Study of the genetic transmission of hypercholesterolemia and hypertriglycendemia in a 195 member kindred
    • Elston RC, Namboodiri KK, Glueck CJ, Fallat R, Tsang R, Leuba V: Study of the genetic transmission of hypercholesterolemia and hypertriglycendemia in a 195 member kindred. Ann Hum Genet 39:67-83, 1975
    • (1975) Ann Hum Genet , vol.39 , pp. 67-83
    • Elston, R.C.1    Namboodiri, K.K.2    Glueck, C.J.3    Fallat, R.4    Tsang, R.5    Leuba, V.6
  • 139
    • 0020608018 scopus 로고
    • Extensions to pedigree analysis. IV. Covariance components models for multivariate traits
    • Lange K, Boehnke M: Extensions to pedigree analysis. IV. Covariance components models for multivariate traits. Am J Med Genet 14:513-524, 1983
    • (1983) Am J Med Genet , vol.14 , pp. 513-524
    • Lange, K.1    Boehnke, M.2
  • 140
    • 0025170498 scopus 로고
    • A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype
    • Amos CI, Elston RC, Bonney GE, Keats DJB, Berenson GS: A multivariate method for detecting genetic linkage, with application to a pedigree with an adverse lipoprotein phenotype. Am J Hum Genet 47:247-254, 1990
    • (1990) Am J Hum Genet , vol.47 , pp. 247-254
    • Amos, C.I.1    Elston, R.C.2    Bonney, G.E.3    Keats, D.J.B.4    Berenson, G.S.5
  • 142
    • 0025874033 scopus 로고
    • Strategies for the collection of sibling-pair data for genetic studies in type 2 (non-insulin-dependent) diabetes mellitus
    • Froguel P, Velho G, Cohen D, Passa P: Strategies for the collection of sibling-pair data for genetic studies in type 2 (non-insulin-dependent) diabetes mellitus (Letter). Diabetologia 34:685, 1991
    • (1991) Diabetologia , vol.34 , pp. 685
    • Froguel, P.1    Velho, G.2    Cohen, D.3    Passa, P.4
  • 143
    • 0026709919 scopus 로고
    • Do bilineal pedigrees represent a problem for linkage analysis? Basic principles and simulation results for single-gene diseases with no heterogeneity
    • Hodge SE: Do bilineal pedigrees represent a problem for linkage analysis? Basic principles and simulation results for single-gene diseases with no heterogeneity. Genet Epidemiol 9:191-206, 1992
    • (1992) Genet Epidemiol , vol.9 , pp. 191-206
    • Hodge, S.E.1
  • 144
    • 2142790963 scopus 로고
    • Genetic linkage in graded human characters
    • Penrose LS: Genetic linkage in graded human characters. Ann Eugenics 88.233-237, 1937
    • (1937) Ann Eugenics , vol.88 , pp. 233-237
    • Penrose, L.S.1
  • 145
    • 0016690548 scopus 로고
    • Quantitative linkage: A statistical procedure for its detection and estimation
    • Hill AP: Quantitative linkage: a statistical procedure for its detection and estimation. Ann Hum Genet 38:439-449, 1975
    • (1975) Ann Hum Genet , vol.38 , pp. 439-449
    • Hill, A.P.1
  • 146
    • 0016756644 scopus 로고
    • A non-parametric test for linkage with a quantitative character
    • Smith CAB: A non-parametric test for linkage with a quantitative character. Ann Hum Genet 38:451-460, 1975
    • (1975) Ann Hum Genet , vol.38 , pp. 451-460
    • Smith, C.A.B.1
  • 147
    • 0018875847 scopus 로고
    • Simplified formulas for detecting linkage with a quantitative character
    • Bener A, Loesch D, Smith CAB: Simplified formulas for detecting linkage with a quantitative character. Ann Hum Genet 43:249-254, 1980
    • (1980) Ann Hum Genet , vol.43 , pp. 249-254
    • Bener, A.1    Loesch, D.2    Smith, C.A.B.3
  • 148
    • 0020640573 scopus 로고
    • Linkage between a marker locus and a quantitative trait of sibs
    • Cockerham CC, Weir BS: Linkage between a marker locus and a quantitative trait of sibs. Am J Hum Genet 35:263-273, 1083
    • (1083) Am J Hum Genet , vol.35 , pp. 263-273
    • Cockerham, C.C.1    Weir, B.S.2
  • 150
    • 0023694035 scopus 로고
    • Combined linkage and segregation analysis using regressive models
    • Bonney GE, Lathrop GM, Lalouel J-M: Combined linkage and segregation analysis using regressive models. Am J Hum Genet 43:29-37, 1988
    • (1988) Am J Hum Genet , vol.43 , pp. 29-37
    • Bonney, G.E.1    Lathrop, G.M.2    Lalouel, J.-M.3
  • 151
    • 0026668039 scopus 로고
    • A Monte Carlo method for combined segregation and linkage analysis
    • Guo SW, Thompson EA: A Monte Carlo method for combined segregation and linkage analysis. Am J Hum Genet 51:1111-1126, 1992
    • (1992) Am J Hum Genet , vol.51 , pp. 1111-1126
    • Guo, S.W.1    Thompson, E.A.2
  • 152
    • 0028058128 scopus 로고
    • Robust variance components approach for assessing genetic linkage in pedigrees
    • Amos CI: Robust variance components approach for assessing genetic linkage in pedigrees Am J Hum Genet 54:535-543, 1994
    • (1994) Am J Hum Genet , vol.54 , pp. 535-543
    • Amos, C.I.1
  • 153
    • 0027362259 scopus 로고
    • Extended multipoint identity-by-descent analysis of human quantitative traits: Efficiency, power, and modelling considerations
    • Schork NJ: Extended multipoint identity-by-descent analysis of human quantitative traits: efficiency, power, and modelling considerations Am J Hum Genet 53:1306-1319, 1993
    • (1993) Am J Hum Genet , vol.53 , pp. 1306-1319
    • Schork, N.J.1
  • 154
    • 0029001682 scopus 로고
    • Extreme discordant sib pairs for mapping quantitative trait loci in humans
    • Risch N, Zhang H: Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 208:1584-1589, 1995
    • (1995) Science , vol.208 , pp. 1584-1589
    • Risch, N.1    Zhang, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.