Active intestinal secretion of new quinolone antimicrobials and the partial contribution of P-glycoprotein

Journal of Pharmacy and Pharmacology

Volumn 53, Issue 5, 2001, Pages 699-709

  Naruhashi, Kazumasa ^a   Tamai, Ikumi ^a,b   Inoue, Natsuko ^a   Muraoka, Hiromi ^a   Sai, Yoshimichi ^a,b   Suzuki, Nagao ^a   Tsuji, Akira ^a,b  

^a KANAZAWA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 ACETAMIDO 4' ISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; 4 AMINOHIPPURIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; CYCLOSPORIN A; GENISTEIN; GLYCOPROTEIN P; GREPAFLOXACIN; LEVOFLOXACIN; PROBENECID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISPOSITION; DRUG INHIBITION; DRUG TRANSPORT; DUODENUM MUCOSA; HUMAN; HUMAN CELL; ILEUM MUCOSA; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; INTESTINE SECRETION; JEJUNUM MUCOSA; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTI-INFECTIVE AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL LINE; FLUOROQUINOLONES; HUMANS; INTESTINAL ABSORPTION; MALE; MICE; P-GLYCOPROTEIN; P-GLYCOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035023064     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357011775820     Document Type: Article

References (23)

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