Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing

European Journal of Immunology

Volumn 34, Issue 9, 2004, Pages 2459-2470

  Su, Michael Wei Chih ^a   Pyarajan, Saiju ^a,d   Chang, Jin Hong ^a   Yu, Chao Lan ^a   Jin, Yong Jiu ^a,d   Stierhof, York Dieter ^b   Walden, Peter ^c   Burakoff, Steven J ^a,d  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antigens peptides epitopes; CTL; Cytotoxicity; Signal transduction

Indexed keywords

CD8 ANTIGEN; CYTOKINE; FAS ANTIGEN; FAS LIGAND; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OVALBUMIN; PEPTIDE; PERFORIN; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; DNA BINDING PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR PROTEIN; PORE FORMING CYTOTOXIC PROTEIN; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CELL KILLING; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; ELECTRON MICROSCOPY; GENETIC TRANSCRIPTION AND TRANSLATION; INCUBATION TIME; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; BIOSYNTHESIS; CYTOTOXICITY; ENZYME ACTIVATION; EXOCYTOSIS; HUMAN; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

CYTOTOXICITY, IMMUNOLOGIC; DNA-BINDING PROTEINS; ENZYME ACTIVATION; EXOCYTOSIS; HUMANS; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHOSPHORYLATION; PORE FORMING CYTOTOXIC PROTEINS; T-LYMPHOCYTES, CYTOTOXIC; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4644257445     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425096     Document Type: Article

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