Cutting edge: CTLs rapidly capture membrane fragments from target cells in a TCR signaling-dependent manner

Journal of Immunology

Volumn 166, Issue 6, 2001, Pages 3645-3649

  Hudrisier, D ^a   Riond, J ^a   Mazarguil, H ^a   Gairin, J E ^a   Joly, E ^a  

^a CHU PURPAN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; CELL SURFACE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; INTERNALIZATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

EID: 0035869425     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.6.3645     Document Type: Article

References (19)

1. Serial triggering of many T-cell receptors by a few peptide-MHC complexes
2. TCR-mediated internalization of peptide-MHC complexes acquired by T cells
3. T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells
4. Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new Vα family
5. Genetically encoded and post-translationally modified forms of a major histocompatibility complex class I-restricted antigen beating a glycosylation motif are independently processed and co-presented to cytotoxic T lymphocytes
6. b: Application to the design of high-affinity, allele-specific peptides
7. + CTL clones is determined by the frequency of serial TCR engagement
8. b cytotoxic T lymphocytes
9. Class II MHC/peptide complexes are released from APC and are acquired by T cell responders during specific antigen recognition
10. + T cells
11. CD8 modulation of T-cell antigen receptor-ligand interactions on living cytotoxic T lymphocytes
12. Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers
13. Kinetics and extent of protein tyrosine kinase activation in individual T cells upon antigenic stimulation
14. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy
15. The dynamics of T cell receptor signaling: Complex orchestration and the key roles of tempo and cooperation
16. + CTLs
17. The bride of sevenless and sevenless interaction; internalization of a transmembrane ligand
18. Patrilocal cell-cell interactions: Sevenless captures its bride
19. + T lymphocytes naturally infected with human T cell lymphotropic virus type I