The nature of nurture: A genomewide association scan for family chaos

Behavior Genetics

Volumn 38, Issue 4, 2008, Pages 361-371

  Butcher, Lee M ^a   Plomin, Robert ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Community sample; Family chaos; GE correlation; Genomewide association; Microarrays

Indexed keywords

ARTICLE; BEHAVIOR GENETICS; COGNITION; GENE ENVIRONMENT CORRELATION; GENE FREQUENCY; GENETIC CORRELATION; GENOME ANALYSIS; GENOTYPE; HOME ENVIRONMENT; HUMAN; MICROARRAY ANALYSIS; QUALITY CONTROL; QUANTITATIVE TRAIT LOCUS; QUESTIONNAIRE; SINGLE NUCLEOTIDE POLYMORPHISM; TWINS;

ADULT; CHILD; COGNITION; CONFUSION; ENVIRONMENT; FAMILY; GENOME, HUMAN; HUMANS; INTERPERSONAL RELATIONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARENT-CHILD RELATIONS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 46149101207     PISSN: 00018244     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10519-008-9198-z     Document Type: Article

References (52)

1. Balding DJ (2006) A tutorial on statistical methods for population association studies. Nat Genet 7:781-791
2. Bell RQ (1968) A reiteration of the direction of effects in socialization. Psycholog Rev 75:81-95
3. Brohede J, Dunne R, McKay JD, Hannan GN (2006) PPC: an algorithm for accurate estimation of SNP allele frequencies in small equimolar pools of DNA using data from high density microarrays. Nucleic Acids Res 33:e142
4. Butcher LM, Meaburn E, Liu L, Hill L, Al-Chalabi A, Plomin R et al (2004) Genotyping pooled DNA on microarrays: A systematic genome screen of thousands of SNPs in large samples to detect QTLs for complex traits. Behav Genet 34:549-555
5. Butcher LM, Meaburn E, Dale PS, Sham P, Schalkwyk L, Craig IW et al (2005a) Association analysis of mild mental impairment using DNA pooling to screen 432 brain-expressed SNPs. Mol Psychiatry 10:384-392
6. Butcher LM, Meaburn E, Knight J, Sham PC, Schalkwyk LC, Craig IW et al (2005b) SNPs, microarrays, and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6,000 children. Hum Mol Genet 14:1315-1325
7. Butcher LM, Davis OSP, Craig IW, Plomin R (2007) Genomewide QTL association scan of general cognitive ability using pooled DNA and 500 K SNP microarrays. Genes, Brain and Behavior, (Epub ahead of print; doi: 10.1111/j.1601-183X.2007.00368.x)
8. Carlson CS, Eberle MA, Kruglyak L, Nickerson DA (2004) Mapping complex disease loci in whole-genome association studies. Nature 429:446-452
9. Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW et al (2002) Role of genotype in the cycle of violence in maltreated children. Science 297:851-854
10. Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, Harrington H et al (2003) Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301:386-389
11. Craig DW, Huentelman MJ, Hu-Lince D, Zismann VL, Kruer MC, Lee AM et al (2005) Identification of disease causing loci using an array-based genotyping approach on pooled DNA. BMC Genomics 6:138
12. Darvasi A, Soller M (1994) Selective DNA pooling for determination of linkage between a molecular marker and a quantitative trait locus. Genetics 138:1365-1373
13. Dawkins R (1982) The extended phenotype. WH Freeman, Oxford
14. Dawkins R (2004) Extended phenotype-but not too extended. A reply to Laland, Turner and Jjablonka. Biol Philos 19:377-396
15. Dick DM, Agrawal A, Schuckit MA, Bierut L, Hinrichs A, Fox L et al (2006) Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction. J Stud Alcohol 67:185-194
16. Dumas JE, Nissley J, Nordstrom A, Smith EP, Prinz RJ, Levine DW (2005) Home chaos: sociodemographic, parenting, interactional, and child correlates. J Clin Child Adolesc Psychol 34:93-104
17. Freeman B, Smith N, Curtis C, Huckett L, Mill J, Craig I (2003) DNA from buccal swabs recruited by mail: evaluation of storage effects on long-term stability and suitability for multiplex polymerase chain reaction genotyping. Behav Genet 33:67-72
18. Harlaar N, Butcher LM, Meaburn E, Craig IW, Plomin R (2005) A behavioural genomic analysis of DNA markers associated with general cognitive ability in 7-year-olds. J Child Psychol Psychiatry 46:1097-1107
19. Hirschhorn JN, Daly MJ (2005) Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 6:95-108
20. Jaffee SR, Price TS (2007) Gene-environment correlations: a review of the evidence and implications for prevention of mental illness. Mol Psychiatry 12:432-442
21. Kendler KS, Baker JH (2007) Genetic influences on measures of the environment: a systematic review. Psychol Med 37:615-626
22. Kendler KS, Eaves LJ (1986) Models for the joint effects of genotype and environment on liability to psychiatric illness. Am J Psychiatry 143:279-289
23. Kirov G, Nikolov I, Georgieva L, Moskvina V, Owen MJ, O'Donovan MC (2006) Pooled DNA genotyping on Affymetrix SNP genotyping arrays. BMC Genomics 7:27
24. Knight J, Sham P (2006) Design and analysis of association studies using pooled DNA from large twin samples. Behav Genet 36:665-677
25. Liu Q-R, Drgon T, Walther D, Johnson C, Poleskaya O, Hess J et al (2005) Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples. Proc Nat Acad Sci USA 102:11864-11869
26. Lucht M, Barnow S, Schroeder W, Grabe HJ, Finckh U, John U et al (2006) Negative perceived paternal parenting is associated with dopamine D2 receptor exon 8 and GABA(A) alpha 6 receptor variants: an explorative study. Am J Med Genet Part B Neuropsychiatr Genet 141:167-172
27. Matheny AP, Wachs TD, Ludwig JL, Phillips K (1995) Bringing order out of chaos: psychometric characteristics of the Confusion, Hubbub and Order Scale. J Appl Dev Psychol 16:429-444
28. Meaburn E, Butcher LM, Liu L, Fernandes C, Hansen V, Al-Chalabi A et al (2005) Genotyping DNA pools on microarrays: tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics 6:52
29. Meaburn E, Butcher LM, Schalkwyk LC, Craig IW, Plomin R (2006) Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans. Nucleic Acids Res 34:e27
30. Meaburn EL, Harlaar N, Craig IW, Schalkwyk LC, Plomin R (2007) Quantitative trait locus association scan of early reading disability and ability using pooled DNA and 100 K SNP microarrays in a sample of 5760 children. Molecular Psychiatry, Aug 7, (Epub ahead of print; doi:10.1038/sj.mp.4002063 )
31. Neale BM, Sham PC (2004) The future of association studies: gene-based analysis and replication. Am J Hum Genet 75:353-362
32. Newton-Cheh C, Hirschhorn JN (2005) Genetic association studies of complex traits: design and analysis issues. Mutat Res 573:54-59
33. Norton N, Williams NM, O'Donovan MC, Owen MJ (2004) DNA pooling as a tool for large-scale association studies in complex traits. Ann Med 36:146-152
34. Oliver B, Plomin R (2007) Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Res Hum Genet 10(1):96-105
35. Pe'er I, de Bakker PIW, Maller J, Yelensky R, Altshuler D, Daly MJ (2006) Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet 38:663-667
36. Pearson JV, Huentelman MJ, Halperin RF, Tembe WD, Melquist S, Homer N et al (2007) Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. Am J Hum Genet 80:126-139
37. Petrill SA, Pike A, Price TS, Plomin R (2004) Chaos in the home and socioeconomic status are associated with cognitive development in early childhood: environmental risks identified in a genetic design. Intelligence 32:445-460
38. Pike A, Iervolino A, Eley T, Price TS, Plomin R (2006) Environmental risk and young children's cognitive and behavioral development. Int J Behav Dev 30:55-66
39. Plomin R (1994) Genetics and experience: the interplay between nature and nurture. Sage Publications Inc, Thousand Oaks, California
40. Plomin R, Bergeman CS (1991) The nature of nurture: genetic influences on "environmental" measures. Behav Brain Sci 14:373-427
41. Plomin R, Davis OSP (2006) Gene-environment interactions and correlations in the development of cognitive abilities and disabilities. In: MacCabe J, O'Daly O, Murray RM, McGuffin P, Wright P (Eds) Beyond nature and nurture: genes, environment and their interplay in psychiatry. Thomson Publishing Services, Andover, UK, pp 35-45
42. Plomin R, DeFries JC, Loehlin JC (1977) Genotype-environment interaction and correlation in the analysis of human behaviour. Psycholog Bull 85:309-322
43. Purcell S, Cherny SS, Sham PC (2003) Genetic power calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 19:149-150
44. Rowe DC (1981) Environmental and genetic influences on dimensions of perceived parenting: a twin study. Dev Psychol 17:203-208
45. Rowe DC (1983) Biometrical genetic models of self-reported delinquent behavior: a twin study. Behav Genet 13:473-489
46. Simpson CL, Knight J, Butcher LM, Hansen VK, Meaburn E, Schalkwyk LC et al (2005) A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Res 33:e25
47. The International HapMap Consortium (2003) The International HapMap Project. Nature 426:789-796
48. The International HapMap Consortium (2005) A haplotype map of the human genome. Nat Genet 437:1299-1320
49. Thomas DC, Haile RW, Duggan D (2005) Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet 77:337-345
50. Tobler AR, Short S, Andersen MR, Paner TM, Briggs JC, Lambert SM et al (2005) The SNPlex genotyping system: a flexible and scalable platform for SNP genotyping. J Biomol Tech 16:398-406
51. Trouton A, Spinath FM, Plomin R (2002) Twins early development study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behaviour problems in childhood. Twin Res 5:444-448
52. Wang WY, Barratt BJ, Clayton DG, Todd JA (2005) Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 6:109-118