Gating motions in voltage-gated potassium channels revealed by coarse-grained molecular dynamics simulations

Journal of Physical Chemistry B

Volumn 112, Issue 11, 2008, Pages 3277-3282

  Treptow, Werner ^a,c   Marrink, Siewert J ^b   Tarek, Mounir ^c,d  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c NANCY UNIVERSITÉ   (France)

^d UNIVERSITÉ DE LORRAINE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALI METALS; CELL MEMBRANES; DYNAMICS; MECHANISMS; MODEL STRUCTURES; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; MOLECULES; NANOFLUIDICS; POTASSIUM; QUANTUM CHEMISTRY;

ACTIVATION MECHANISMS; AMERICAN CHEMICAL SOCIETY (ACS); CHANNEL GATING; CLOSED FORM; CLOSED STRUCTURES; COARSE-GRAINED MOLECULAR DYNAMICS SIMULATIONS; CONFORMATIONAL CHANGES; FORCE FIELD (FF); GATING MECHANISMS; LATERAL DISPLACEMENT (LD); MEMBRANE POTENTIALS; MOLECULAR DYNAMICS SIMULATIONS (MDS); MOLECULAR LEVELS; OPEN VOLTAGE; PROPERTY (S); STRUCTURAL MODEL (SM); TETRAMERIZATION; TRANSMEMBRANE (TM) PROTEINS; UPWARD MOTION; VOLTAGE GATED POTASSIUM CHANNELS; VOLTAGE SENSORS;

CRYSTAL STRUCTURE;

KV CHANNEL INTERACTING PROTEIN; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CHEMISTRY; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; TIME;

COMPUTER SIMULATION; ELECTROPHYSIOLOGY; ION CHANNEL GATING; KV CHANNEL-INTERACTING PROTEINS; MEMBRANE POTENTIALS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; TIME FACTORS;

EID: 45949109759     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp709675e     Document Type: Article

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