Characterization of synthetic oligonucleotides containing biologically important modified bases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Analytical Biochemistry

Volumn 379, Issue 2, 2008, Pages 196-207

  Cui, Zhengfang ^a   Theruvathu, Jacob A ^a   Farrel, Alvin ^a   Burdzy, Artur ^a   Sowers, Lawrence C ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Base analogs; Isotope cluster; MALDI TOF; Oxidative damage; Synthetic oligonucleotides

Indexed keywords

CHEMICAL ANALYSIS; DESORPTION; INDUCTIVELY COUPLED PLASMA; ISOTOPES; MASS SPECTROMETRY; PURIFICATION; SUBSTRATES;

BASE ANALOGS; INTERPRETATION OF EXPERIMENTS; MALDI-TOF; MATRIX-ASSISTED LASER DESORPTION/IONIZATION-TIME-OF-FLIGHT MASS SPECTROMETRY; METHOD OF CHARACTERIZATIONS; MODIFIED OLIGONUCLEOTIDES; OLIGONUCLEOTIDE SYNTHESIS; OXIDATIVE DAMAGE;

OLIGONUCLEOTIDES;

ISOTOPE; OLIGONUCLEOTIDE;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL REACTION; DNA HELIX; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; PURIFICATION; SYNTHESIS; THERMODYNAMICS;

EID: 45849102049     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.04.031     Document Type: Article

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