5-Chloro-2'-deoxyuridine cytotoxicity results from base excision repair of uracil subsequent to thymidylate synthase inhibition

Mutation Research - DNA Repair

Volumn 459, Issue 2, 2000, Pages 161-169

  Brandon, Mark L ^a,b   Mi, Li Jun ^a,b   Chaung, Wenren ^a,b   Teebor, George ^a,b   Boorstein, Robert J ^a,b  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b Kaplan Cancer Center   (United States)

Author keywords

5 Chloro 2' deoxyuridine; DNA base excision repair; Thymidylate synthase; Uracil DNA glycosylase; V79 cells

Indexed keywords

5 CHLORODEOXYCYTIDINE; DNA GLYCOSYLTRANSFERASE; SINGLE STRANDED DNA; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE; URACIL;

ANIMAL CELL; ARTICLE; CELL STRAIN V 79; CHO CELL; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVITY; EXCISION REPAIR; FLOW CYTOMETRY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; BASE PAIRING; CELL LINE; CRICETINAE; CRICETULUS; DEOXYURIDINE; DNA; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; N-GLYCOSYL HYDROLASES; PENTOXYL; THYMIDYLATE SYNTHASE; URACIL;

CRICETINAE; CRICETULUS GRISEUS; ZIZIPHUS MAURITIANA;

EID: 0034689142     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00061-0     Document Type: Article

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