Oxidative generation of guanine radicals by carbonate radicals and their reactions with nitrogen dioxide to form site specific 5-guanidino-4-nitroimidazole lesions in oligodeoxynucleotides

Chemical Research in Toxicology

Volumn 16, Issue 8, 2003, Pages 966-973

  Joffe, Avrum ^a   Mock, Steven ^a   Yun, Byeong Hwa ^a   Kolbanovskiy, Alexander ^a   Geacintov, Nicholas E ^a   Shafirovich, Vladimir ^a  

^a NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',3',5' TRI O ACETYLGUANOSINE; 5 GUANIDINO 4 NITROIMIDAZOLE; CARBONIC ACID; GUANINE DERIVATIVE; GUANOSINE DERIVATIVE; IMIDAZOLE DERIVATIVE; NITROGEN DIOXIDE; OLIGODEOXYNUCLEOTIDE DERIVATIVE; RADICAL; SULFATE; UNCLASSIFIED DRUG;

ARTICLE; CODON; DNA SEQUENCE; EXON; GENE MUTATION; GENE SEQUENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MODEL; OXIDATION; PHOTOCHEMISTRY; SYNTHESIS; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

ACETALDEHYDE; CARBONATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA ADDUCTS; FREE RADICALS; GUANINE; NITROGEN DIOXIDE; NITROIMIDAZOLES; NUCLEIC ACID CONFORMATION; OLIGONUCLEOTIDES; OXIDATION-REDUCTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0041360606     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx025578w     Document Type: Article

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