New synthesis of 5-carboxy-2′-deoxyuridine and its incorporation into synthetic oligonucleotides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1073-1075

  Guerniou, V ^a   Gasparutto, D ^a,b   Sauvaigo, S ^a   Favier, A ^a   Cadet, J ^a  

^a Lab Lesions des Acides Nucleiques   (France)

^b CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXY 2' DEOXYURIDINE; DEOXYURIDINE DERIVATIVE; MENADIONE; OLIGONUCLEOTIDE; PHOSPHORAMIDIC ACID DERIVATIVE; THYMIDINE; TRIFLURIDINE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; CONFERENCE PAPER; HYDROLYSIS; NUCLEOTIDE METABOLISM; OXIDATION; PHOTOSENSITIZATION; SOLID; SYNTHESIS;

AMIDES; DEOXYURIDINE; HYDROLYSIS; INDICATORS AND REAGENTS; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHORIC ACIDS;

EID: 0141708092     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120022739     Document Type: Conference Paper

References (3)

1. Berthod, T.; Cadet, J.; Molko, D. 5-Carboxy-2′-deoxyuridine, a new photooxidation product of thymidine. J. Photochem. Photobiol. 1997, 104, 97-104.
2. Berthod, T.; Pétillot, Y.; Guy, A.; Cadet, J.; Molko, D. Synthesis of oligonucleotides containing 5-carboxy-2′-deoxyuridine at defined sites. J. Org. Chem. 1996, 61, 6075-6078.
3. Jones, M.F. The stability of trifluorothymidine: Hydrolysis in buffered aqueous solutions. J. Pharm. Pharmacol. 1981, 33 (5), 274-278.