Rhodopsin: Structural basis of molecular physiology

Physiological Reviews

Volumn 81, Issue 4, 2001, Pages 1659-1688

  Menon, Santosh T ^a   Han, May ^a   Sakmar, Thomas P ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; RHODOPSIN; TRANSDUCIN; VISUAL PIGMENT;

COLOR VISION; CRYSTAL STRUCTURE; HUMAN; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SPECTROSCOPY; VISUAL SYSTEM;

EID: 0034784920     PISSN: 00319333     EISSN: None     Source Type: Journal    
DOI: 10.1152/physrev.2001.81.4.1659     Document Type: Review

References (269)

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107. Chromophore structural changes in rhodopsin from nanoseconds to microseconds following pigment photolysis
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155. The amino terminus of the fourth cytoplasmic loop of rhodopsin modulates rhodopsin-transducin interaction
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157. Phosphorylation sites in bovine rhodopsin
158. Structural and functional rescue of murine rod photoreceptors by human rhodopsin transgene
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160. Absorption spectra of human cone pigments
161. Absorption spectra of the hybrid pigments responsible for anomalous color vision
162. Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand
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180. Spectral tuning of pigments underlying red-green color vision
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182. Interaction between photoactivated rhodopsin and the C-terminal peptide of transducin alpha-subunit studied by FTIR spectroscopy
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184. Structural and enzymatic aspects of rhodopsin phosphorylation
185. X-ray diffraction analysis of three-dimensional crystals of bovine rhodopsin obtained from mixed micelles
186. Highly selective separation of rhodopsin from bovine rod outer segment membranes using combination of divalent cation and alkyl(thio)glucoside
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188. The ligand-binding domain of rhodopsin and other G protein-linked receptors
189. Design, chemical synthesis, and expression of genes for the three human color vision pigments
190. The carboxyl terminus of bovine rhodopsin is not required for G protein activation
191. Resonance Raman spectroscopy of rhodopsin in retinal disk membranes
192. Rhodopsin and bacteriorhodopsin: Structure-function relationships
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194. Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin
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203. Sequence alignment of the G-protein coupled receptor superfamily
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205. Polyenes and vision
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207. Activating mutations of rhodopsin and other G protein-coupled receptors
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210. Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin
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214. Constitutively active mutants of rhodopsin
215. The role of hormone receptors and GTP-regulatory proteins in membrane transduction
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219. Assays for activation of opsin by all-trans-retinal
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222. Properties and photoactivity of rhodopsin mutants
223. Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin
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225. Projection structure of rhodopsin
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229. Defects in G protein-coupled signal transduction in human disease
230. Structure and function of G protein-coupled receptors
231. A diffusible factor from normal retinal cells promotes rod photoreceptor survival in an in vitro model of retinitis pigmentosa
232. Tertiary interactions between the fifth and sixth transmembrane segments of rhodopsin
233. G protein-coupled receptor activation: Analysis of a highly constrained, "straitjacketed" rhodopsin
234. Visual excitation and recovery
235. Electron diffraction analysis of structural changes in the photocycle of bacteriorhodopsin
236. Molecular mechanism of vectorial proton translocation by bacteriorhodopsin
237. Protein conformational changes in the bacteriorhodopsin photocycle
238. Time-resolved rhodopsin activation currents in a unicellular expression system
239. Rhodopsin mutations in autosomal dominant retinitis pigmentosa
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241. Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa
242. Transducin activation by the bovine opsin apoprotein
243. Evidence for multiple, biochemically distinguishable states in the G protein-coupled receptor, rhodopsin
244. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
245. C-terminal peptides of rhodopsin. Determination of the optimum sequence for recognition of retinal transducin
246. A pathologic study of degeneration of the rod and cone populations of the rhodopsin Pro347Leu transgenic pigs
247. Arrangement of rhodopsin transmembrane alpha-helices
248. Selective stabilization of the high affinity binding conformation of glucagon receptor by the long splice variant of Galpha(s)
249. 13C-labeling and 1-D rotational resonance MAS NMR
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251. The molecular basis of visual excitation
252. Expression of a mutant opsin gene increases the susceptibility of the retina to light damage
253. Vibrationally coherent photochemistry in the femtosecond primary event of vision
254. A locus control region adjacent to the human red and green visual pigment genes
255. --binding site in the human red and green color vision pigments
256. Altered cAMP levels in retinas from transgenic mice expressing a rhodopsin mutant
257. Effects of carboxyl-terminal truncation on the stability and G protein-coupling activity of bovine rhodopsin
258. Opsin localization and rhodopsin photochemistry in a transgenic mouse model of retinitis pigmentosa
259. Distinct roles of the second and the third cytoplasmic loops of bovine rhodopsin in G protein activation
260. Thermal activation of the visual transduction mechanism in retinal rods
261. Pre-lumirhodopsin and the bleaching of visual pigments
262. State-dependent disulfide cross-linking in rhodopsin
263. Tertiary interactions between transmembrane segments 3 and 5 near the cytoplasmic side of rhodopsin
264. The location of the chromophore in rhodopsin: A photoaffinity study
265. Effect of carboxylic acid side chains on the absorption maximum of visual pigments
266. Transducin activation by rhodopsin without a covalent bond to the 11-cis-retinal chromophore
267. Characterization of the mutant visual pigment responsible for congenital night blindness: A biochemical and Fourier-transfom infrared spectroscopy study