Small molecule activator of the human epithelial sodium channel

Journal of Biological Chemistry

Volumn 283, Issue 18, 2008, Pages 11981-11994

  Lu, Min ^a   Echeverri, Fernando ^a   Kalabat, Dalia ^a   Laita, Bianca ^a   Dahan, David S ^a   Smith, Raymond D ^a   Xu, Hong ^a   Staszewski, Lena ^a   Yamamoto, Jeff ^a   Ling, Jing ^a   Hwang, Nancy ^a   Kimmich, Rachel ^a   Li, Peter ^a   Patron, Erika ^a   Keung, Walter ^a   Patron, Andrew ^a   Moyer, Bryan D ^a  

^a Senomyx   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; SODIUM;

DOSE-DEPENDENT MANNER; EPITHELIAL MEMBRANES; EPITHELIAL SODIUM CHANNELS; EXTRACELLULAR DOMAINS; HETEROLOGOUS CELLS; NEONATAL RESPIRATORY DISTRESS SYNDROMES; SMALL MOLECULE ACTIVATION; SMALL MOLECULES;

MOLECULES;

AMILORIDE; EPITHELIAL SODIUM CHANNEL; FURIN; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYPOTENSION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PSEUDOHYPOALDOSTERONISM; RESPIRATORY DISTRESS SYNDROME; ANIMAL; CELL LINE; CHANNEL GATING; CHEMISTRY; DRUG EFFECT; EXTRACELLULAR SPACE; FEMALE; METABOLISM; MOLECULAR LIBRARY; MOUSE; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; XENOPUS;

AMILORIDE; ANIMALS; CELL LINE; EPITHELIAL SODIUM CHANNEL; EXTRACELLULAR SPACE; FEMALE; FURIN; HUMANS; ION CHANNEL GATING; MICE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; PSEUDOHYPOALDOSTERONISM; SMALL MOLECULE LIBRARIES; XENOPUS;

EID: 45549085339     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M708001200     Document Type: Article

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