Differential expression of RNA and protein of the three pore-forming subunits of the amiloride-sensitive epithelial sodium channel in taste buds of the rat

Journal of Histochemistry and Cytochemistry

Volumn 47, Issue 1, 1999, Pages 51-64

  Kretz, Oliver ^a   Barbry, Pascal ^b   Bock, Rudolf ^a   Lindemann, Bernd ^a,c  

^a SAARLAND UNIVERSITY   (Germany)

^b CNRS   (France)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Amiloride; ENaC; Immunohistochemistry; RT PCR; Taste

Indexed keywords

AMILORIDE; SODIUM CHANNEL;

ALPHA CHAIN; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; BINDING SITE; CHANNEL GATING; EPITHELIUM CELL; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TASTE BUD;

ANIMALIA; EUKARYOTA;

EID: 0032929132     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215549904700106     Document Type: Article

References (80)

1. + channel subunits. Am J Physiol 271:C605-611
2. Avenet P, Lindemann B (1991) Noninvasive recording of receptor cell action potentials and sustained currents from single taste buds maintained in the tongue: the response to mucosal NaCl and amiloride. J Membr Biol 124:33-41
3. Avenet P, Lindemann B (1988) Amiloride-blockahle sodium currents in isolated taste receptor cells. J Membrane Biol 105:245-255
4. + absorption. Am J Physiol 273:0571-585
5. Béhé P, DeSimone JA, Avenet P, Lindemann B (1990) Membrane currents in taste cells of the rat fungiform papilla: evidence for two types of Ca currents and inhibition of K currents by saccharin. J Gen Physiol 96:1061-1084
6. 2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat. J Physiol 490:325-336
7. Bonifacino JS, Suzuki CK, Lippincott-Schwartz J, Weissman AM, Klausner RD (1989) Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly. J Cell Biol 109:73-83
8. Boudreau JC, Sivakumar L, Do LT, White TD, Oravec J, Hoang NK (1985) Neurophysiology of geniculate ganglion (facial nerve) taste systems: species comparisons. Chem Senses 10:89-127
9. Boughter JDJ, Pumplin DW, Yu C, Christy RC, Smith DV (1997) Differential expression of alpha-gustducin in the taste bud populations of the rat and hamster. J Neurosci 17:2852-2858
10. Brown D, Sorscher EJ, Ausiello A, Benos DJ (1989) Immunocytochemical localization of Na ' channels in rat kidney medulla. AmJ Physiol 256:F366-369
11. Brown D, Stow JL (1996) Protein trafficking and polarity in kidney epithelium: from cell biology to physiology. Physiol Rev 76:245-297
12. Canessa CM, Horisberger J-D, Rossier BC (1993) Epithelial sodium channel related to proteins involved in neurodegeneration. Nature 361:467-470
13. + channel is made of three homologous subunits. Nature 36 7:463-467
14. Chassande O, Renard S, Barhry P, Lazdunski M (1994) The human gene for diamine oxidase, an amiloride binding protein. J Biol Chem 269:14484-14489
15. Chraibi A, Vallet V, Firsov D, Hess SK, Horisberger J-D (1998) Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus Oocytes. J Gen Physiol 111:127-138
16. Contreras RJ, Kosten T, Prank MK (1984) Activity in salt taste fibers: peripheral mechanism for media ting changes in salt intake. Chem Senses 8:275-288
17. Doolin RE, Gilbertson TA (1996) Distribution and characterization of functional amiloride-sensitive sodium channels in rat tongue. J Gen Physiol 107:545-554
18. Due C, Harman N, Canessa CM, Bonvalet J-P, Rossier BC (1994) Cell-specific expression of epithelial sodium channel a, b, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry. J Cell Biol 127:1907-1921
19. Farman N (1997) Renal expression of rENaC: tissue specificity and regulation. Physiologist 40:A-9
20. + channel along rat respiratory tract. Am J Physiol 272:C131-141
21. Firsov D, Gautschi I, Merillat AM, Rossier BC, Schild L (1998) The heterotetrameric architecture of the epithelial sodium channel (ENaC). EMBO J 17:344-352
22. Formaker BK, Hill DL (1991) Lack of amiloride sensitivity in SHR and WKY glossopharyngeal taste responses to NaCl. Physiol Behav 50:765-769
23. Frank ME, Bieber SL, Smith DV (1988) The organization of taste sensibilities in hamster chorda tympani nerve fibers. J Gen Physiol 91:861-896
24. + channels: function, structure, and regulation. Physiol Rev 77:359-396
25. Gilbertson TA, Avenet P, Kinnamon SC, Roper SD (1992) Proton currents through amiloride-sensitive Na channels in hamster taste cells: role in acid transduction. J Gen Physiol 100:803-824
26. + channels in isolated hamster taste cells: enhancement by vasopressin and cAMP. Neuron 10:9 31-942
27. Heck GL, Mierson S, DeSimone JA (1984) Salt taste transduction occurs through anamiloride-sensitive sodium transport pathway. Science 223:403-405
28. Hettinger TP, Frank ME (1990) Specificity of amiloride inhibition of hamster taste responses. Brain Res 513:24-34
29. Höfer D, Püschel B, Drenckhahn D (1996) Taste receptor-like cells in the rat gut identified by expression of a-gustducin. Proc Natl Acad Sci USA 93:6631-6634
30. Hosley MA, Hughes SE, Mortori LL, Oakley B (1987) A sensitive period for the neural induction of taste buds. J Neurosci 7:2075-2080
31. Klausner RD (1989) Architectural editing: determining the fate of newly synthesized membrane proteins. New Biologist 1:3-8
32. Klausner RD, Sitia R (1990) Protein degradation in the endoplasmic reticulum. Cell 62:611-614
33. + channel. J Biol Chem 266:3907-3915
34. Kosari F, Sheng S, Li J, Mak DO, Foskett JK, Kleyman TR (1998) Suhunit stoichiometry of the epithelial sodium channel. J Biol Chem 273:13469-13474
35. Li XJ, Blackshaw S, Snyder SH (1994) Expression and localization of amiloride-sensitive sodium channels indicate a role for non-taste cells in taste perception. Proc Natl Acad Sci US A 91:1814-1818
36. Li XJ, Xu RH, Guggino WB, Snyder SH (1995) Alternatively spliced forms of the alpha subunit of the epithelial sodium channel: distinct sites for amiloride binding and channel pore. Mol Pharmacol 47:11.33-1140
37. + channel subunits in rat taste cells. Chem Senses 22:735
38. + salt. J Comp Neurol
39. Lin C, Musch M, Meo P, Zebrowitz J, Chang E, Kleyman TR (1994) Anti-idiotypic antibodies to delineate epitope specificity of anti-amiloride antibodies. Am J Physiol 267:C821-826
40. Lin C, Worrell RT, Kieber-Emmons T, Canessa CM, Rossier BC, Eaton DC, Kleyman TR (1994b) Mutagenesis of a putative amiloride-binding site of the epithelial Na channel. J Am Soc Nephrol 5:291
41. Lindemann B (1996) Taste reception. Physiol Rev 76:719-766
42. Lindemann B (1997) Sodium taste. Curr Opin Nephrol Hyperten 6:425-429
43. Lindemann B, Barbry P, Kretz O, Bock R (1998) Occurrence of ENaC subunit mRNA and immunocytochemistry of the channel subunits in taste buds of the rat vallate papilla. Ann NY Acad Sci 855:116-127
44. Lingueglia E, Champigny G, Lazdunski M, Barbry P (1995) Cloning of the amiloride-sensitive FMRFamide pepride-gated sodium channel. Nature 378:730-733
45. + channel are differently regulated by aldosterone. J Biol Chem 269:13736-13739
46. + channel - a new channel type with homologies to Caenorhabditis elegans degenerins. FEBS Eett 318:95-99
47. Lippincott-Schwartz J, Bonifacino JS, Yuan EC, Klausner RD (1988) Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell 54:209-220
48. Loo DDF, Lewis SA, Ifshin MS, Diamond JM (1983) Turnover, membrane insertion, and degradation of sodium channels in rabbit urinary bladder. Science 221:1288-1290
49. May A, Puoti A, Gaeggeler H-P, Horisberger J-D, Rossier B (1997) Early effect of aldosteroneon the rate of synthesis of the epithelial sodium channel alpha subunit in A6 renal cells. J Am Soc Nephrol 8:1813-1822
50. McLaughlin SK, McKinnon PJ, Margolskee RF (1992) Gustducin is a taste-cell-specific G protein closely related to the transducins. Nature 357:563-569
51. Menco BPM, Cunningham AM, Qasba P, Levy N, Reed RR (1997) Putative odour receptors localize in cilia of olfactory receptor cells in rat and mouse: a freeze-substitution ultrastructural study. J Neurocytol 26:297-312
52. Miyamoto T, Miyazaki T, Okada Y, Sato T (1996) Whole-cell recording from non-dissociated taste cells in mouse taste bud. J Neurosci Methods 64:245-252
53. Ninomiya Y, Funakoshi M (1988) Amiloride inhibition of responses of rat single chorda tympani fibers to chemical and electrical tongue stimulations. Brain Res 451:319-325
54. Norgren R, Nishijo H, Travers SP (1989) Taste responses from the entire gustatory apparatus. Ann NY Acad Sci 575:246-264
55. Novotny WF, Chassande O, Baker M, Lazdunski M, Barbry P (1994) Diamine oxidase is the amiloride-binding protein and is inhibited by amiloride analogues. J Biol Chem 269:9921-9925
56. + channel. J Biol Chem 269:12981-12986
57. + channel in colon, lung and kidney. Pflugers Arch 430:299-307
58. Simon SA, Holland VF, Benos DJ, Zamphighi GA (1993) Transcellular and paracellular pathways in lingual epithelia and their influence in taste transduction. Microsc Res Tech 26:196-208
59. Sorscher EJ, Accavitti MA, Keeton D, Steadman E, Frizzell RA, Benos DJ (1988) Antibodies against purified epithelial sodium channel protein from bovine renal papilla. Am J Physiol 255: C835-843
60. Spector AC, Guagliardo NA, St. John SJ (1996) Amiloride disrupts NaCL vs. KCl discrimination performance: implications for salt taste coding in rats. J Neurosci 16:8115-8122
61. + channel (ENaC) by ubiquitination. EMBO J 16:6325-6336
62. Stewart RE, Lasiter PS, Benos DJ, Hill DL (1995) Immunohistochemical correlates of peripheral gustatory sensitivity to sodium and amiloride. Acta Anat 153:310-319
63. Striem BJ, Nairn M, Lindemann B (1991) Generation of cyclic AMP in taste buds of the rat circumvallate papilla in response to sucrose. Cell Physiol Biochem 1:46-54
64. a14 in taste cells of the rat. Jpn J Oral Biol 38:150
65. Takami S, Getchell TV, McLaughlin SK, Margolskee RF, Getchell ML (1994) Human taste cells express the G protein alpha-gustducin and neuron-specific enolase. Mole Brain Res 22:193-203
66. Thomas CP, Doggett NA, Fisher R, Stokes JB (1996) Genomic organization and the 5′-flanking region of the gamma subunit of the human amiloride-sensitive epithelial sodium channel. J Biol Chem 271:26062-26066
67. Tousson A, Alley CD, Sorscher EJ, Brinkley BR, Benos DJ (1989) Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia. J Cell Sci 93:349-362
68. Valentijn JA, Fyfe GK, Canessa CM (in press) Biosynthesis and processing of epithelial sodium channels in Xenopus oocytes. J Biol Chem
69. Vallet V, Chraibin A, Gaegeler H-P, Horisberger J-D, Rossier BC (1997) An epithelial serineprotease activates the amiloride-sensitive sodium channel. Nature 389:607-610
70. Voilley N, Bassilana F, Mignon C, Merscher S, Mattel M-G, Carle GF, Lazdunski M, Barbry P (1995) Cloning, chromosomal localization, and physical linkage of the β and g subunits of (SCNN1B and SCNN1G) of the human epithelial amiloride-sensitive sodium channel. Genomics 28:560-565
71. +channel: from primary structure to function. Comp Biochem Physiol [A] 118:193-200
72. Waldmann R, Champigny G, Bassilana F, Heurteaux C, Lazdunski M (1997) A proton-gated cation channel involved in acid-sensing. Nature 386:173-177
73. + channel. J Biol Chem 270:27411-27414
74. + channel function. J Biol Chem 270:11735-11737
75. Waldmann R, Champigny G, Voilley N, Lauritzen I, Lazdunski M (1996) The mammalian degenerin MDEG, an amiloride-sensitive cation channel activated by mutations causing neurodegeneration in Caenorhabditis elegans. J Biol Chem 271:10433-10436
76. Ward CL, Omura S, Kopito R (1995) Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83:121-127
77. + conductance in rat proximal tubule. Pflugers Arch 434:173-178
78. Ye Q, Heck GL, DeSimone JD (1991) The an ion paradox in sodium taste reception: resolution by voltage-clamp studies. Science 254:724-726
79. + salts: implications for the functional organization of taste receptor cells. J Neurophysiol 70: 167-178
80. + salts in the rat: implications for gustatory transduction. J Gen Physiol 104:885-907