Ion channels as important targets for antiepileptic drug design

Current Drug Targets

Volumn 5, Issue 7, 2004, Pages 589-602

  Yogeeswari, P ^a   Ragavendran, J Vaigunda ^a   Thirumurugan, R ^a   Saxena, A ^a   Sriram, D ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antiepileptic drugs; Calcium ion channel; Epilepsy; H channels; Potassium ion channel; Sodium ion channel; Voltage gated ion channels

Indexed keywords

2 HYDROXY 2 PHENYLNONANAMIDE; 4 AMINO N (2,6 DIMETHYLPHENYL)PHTHALIMIDE; 5 AMINOCARBONYL 10,11 DIHYDRO 5H DIBENZO[A,D]CYCLOHEPTEN 5,10 IMINE; AMELTOLIDE; AMPA RECEPTOR ANTAGONIST; ANTICONVULSIVE AGENT; BATRACHOTOXININ A 20ALPHA BENZOATE; BENZODIAZEPINE DERIVATIVE; BLOCKING AGENT; CARBAMAZEPINE; DIAZEPAM; DRUG METABOLITE; ETHOSUXIMIDE; FELBAMATE; FOSPHENYTOIN SODIUM; GUANIDINE DERIVATIVE; ION CHANNEL; LAMOTRIGINE; LIDOCAINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PIPERAZINE DERIVATIVE; PRODRUG; PYRAZINE DERIVATIVE; SODIUM CHANNEL BLOCKING AGENT; TOPIRAMATE; TRIAZINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VOLTAGE GATED SODIUM CHANNEL; ZONISAMIDE;

CELL MEMBRANE; CENTRAL NERVOUS SYSTEM DISEASE; CHANNEL GATING; DISEASE MODEL; DRUG DESIGN; DRUG EFFICACY; DRUG MECHANISM; DRUG RESEARCH; DRUG STRUCTURE; DRUG TARGETING; DRUG USE; ELECTRIC CONDUCTIVITY; ELECTRIC POTENTIAL; EPILEPSY; EPILEPTOGENESIS; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; HEREDITY; HUMAN; NERVE CELL EXCITABILITY; NERVE CONDUCTION; NERVOUS SYSTEM FUNCTION; NEUROPATHIC PAIN; NONHUMAN; PATHOLOGY; REGULATORY MECHANISM; REVIEW; SEIZURE; SIDE EFFECT; STRUCTURE ACTIVITY RELATION;

ANTICONVULSANTS; CALCIUM CHANNELS; CHEMISTRY, PHARMACEUTICAL; EPILEPSY; HUMANS; ION CHANNELS; POTASSIUM CHANNELS; SODIUM CHANNELS;

EID: 4544375063     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450043345227     Document Type: Review

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