Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons

European Journal of Neuroscience

Volumn 9, Issue 3, 1997, Pages 605-616

  Antonio Lamas, J ^a   Selyanko, A A ^a   Brown, D A ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Ionic currents; Linopirdine; M channels; M currents; Potassium currents; Sympathetic ganglia

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; CALCIUM; CHLORIDE ION; LINOPIRDINE; NEUROTRANSMITTER; NOOTROPIC AGENT; POTASSIUM ION;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN CORTEX; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPOLARIZATION; HIPPOCAMPUS; HYPERPOLARIZATION; MEMBRANE CURRENT; NERVE CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SUPERIOR CERVICAL GANGLION; SYMPATHETIC NERVE CELL;

ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GANGLIA, SYMPATHETIC; INDOLES; ION CHANNELS; POTASSIUM CHANNELS; PYRIDINES; RATS;

EID: 0030959835     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01637.x     Document Type: Article

References (3)

1. Adams, P. R. and Brown, D. A. (1975) Actions of γ-aminobutyric acid on sympathetic ganglion cells. J. Physiol. (Lond.), 250, 85-120.
2. Adams, P. R., Brown, D. A. and Constant!, A. (1982a) M-currents and other potassium currents in bullfrog sympathetic neurones. J. Physiol. (Lond.), 330, 537-572.
3. Adams, P. R., Brown, D. A. and Constanti, A. (1982b) Pharmacological inhibition of the M-current. J. Physiol, 332, 223-262.